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SEM analysis indicated no perceptible difference in the surface characteristics of the miniplates at all time intervals. The stapling device performed well in all cases except when the bovine aorta was too thick for the staples (two cases) or when there was a missed branch at the anastomotic site (one case). Lipid nanoparticles enhance the absorption of cyclosporine A through the gastrointestinal barrier: In vitro and in vivo studies. Incidence of antibodies to adenovirus-associated viruses in patients with tumours or other diseases. It is assumed that, in a negative emotional state, the goal to overcome this negative mood state takes precedence over the goal to succeed in a nonemotional task.

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The effect of a selective estrogen receptor modulator on the progression of spontaneous autoimmune disease in MRL lpr/lpr mice. In the United States, individuals recruited into randomized controlled trials of substance use disorder treatments appear to be very different from individuals receiving treatment in usual care settings. After training, within group comparisons showed that the training groups rated less pain, and in the strength training group ratings of pain at worst differed from the non-training group. The use of immunohistochemistry (IHC) in routinely processed celloidin-embedded human temporal bone section has created a fruitful field in understanding the pathogenesis and pathophysiology of the human inner ear at a molecular level since the early 1990s when the antigen retrieval (AR) technique was developed.

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The search for selective ganglion blocking drugs for therapeutic use. These regulatory mechanisms coordinate to play essential roles in silencing of pluripotency genes and activating key neurodevelopmental genes during cell fate commitment at DNA, histone, chromatin, and RNA levels. Appreciable amounts of the cytokine were produced by lipopolysaccharide (LPS)-stimulated PBMC. It is important to detect patients at high risk for acute exacerbation.

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We evaluated age-related changes in nitric oxide (NO) production in the brains of EL mice, a strain highly susceptible to seizures. Positional cloning of a sequence from the breakpoint of chromosome 9 commonly associated with the loss of cytoadherence. Multivariable analysis and stepwise logistic regression were carried out to evaluate whether the FIGO 2000 scoring system could be simplified. Although DNA-binding proteins are usually thought to find their target sites by one-dimensional pathways, three-dimensional routes may be more common than previously anticipated.

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It is suggested that the increase in closing volume during pregnancy might result in abnormalities of distribution of ventilation sufficient to explain the maternal blood gas disturbances of pregnancy. In order to find a form of therapy which is disease-specific, low-risk and with a high success rate, long-term controlled studies on large groups of patients need to be performed. Geographical genetic variation in the gene encoding VP3 from the Alberta isolate of epizootic hemorrhagic disease virus. A simple method of the determination of lactate in biological fluids

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We find, as many others have reported, that even very coarse stereopsis declines dramatically with age. Impact of 27-hydroxylase (CYP27A1) and 27-hydroxycholesterol in breast cancer. Genes that were queried in at least three studies and assessed to be expressed in at least three studies were considered definitively expressed genes of the human TM.

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Selective inhibition by alcohol and cortisol of natural killer cell activity of lymphocytes from cord blood. In normal kidneys, PN-1 mRNA was detected primarily in glomeruli, most likely in mesangial cells. Sonographic measurement of renal size in normal Indian children. Finally, we evaluate evidence regarding the contribution of HPV to the physiological and pathophysiological processes involved in the transition from fetal to neonatal life, pulmonary gas exchange, high-altitude pulmonary edema, and pulmonary hypertension. After the beneficial demonstration of peripheral opioid receptors in joint synovia, intra-articular opioid injections were used for pain treatment.

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These fossils demonstrate that macroscelideans underwent a significant radiation in the Early Tertiary of Africa. The concentration of Na and Zn in aqueous humor decreased as compared to the values for normal healthy persons. We conclude that the course of epilepsy due to NC in childhood cannot be based exclusively on the number or stage of the parasites. A characteristic finding was amelioration of parkinsonian symptoms after sleep in all patients. There was no other explanation for the difference in biological activity than the criteria of selection.

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Incorporating FEV1 and RV/TLC into the GOLD-COPD or LLN-based definition brings both definitions closer to expert panel diagnosis of COPD, and to daily clinical practice. A Successful Case of Treatment of Colonic Metastasis and Peritoneal Recurrence of Type 4 Gastric Cancer by Using Colectomy and Chemotherapy Effects of mechanical stimulation on cell cycle duration in rat gingival fibroblast progenitor cells. To compare, in a retrospective observational cohort study, the efficacy, tolerability and safety of propiverine and oxybutynin in children with urge incontinence (UI) due to overactive bladder. A proton magnetic resonance spectral editing technique is presented that uses PRESS excitation to achieve spatially localized measurements of brain gamma-aminobutyric acid (GABA).

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nov., a soil bacterium that is able to degrade azo dyes of the Orange II type. Seven sets of plasma concentration-time data were fitted to both a conventional biexponential equation and a gamma equation. Primary hippocampal neurons were prepared from fetal Sprague-Dawley rats, eliminating glia cells by addition of cytosine beta-D-arabinofuranoside at day 2 in vitro (DIV2). Did Carvedilol Really Have More Severe Adverse Events than Propranolol in Cirrhotic Patients?

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This special case joins the other 102 cases which have already been described in the international literature. Sorption behavior of a synthetic antioxidant, polycyclic musk, and an organophosphate insecticide in wastewater sludge. The deduced sequence of Rubisco LSMT did not exhibit regions of significant homology with other protein methyltransferases. As with bacterial communities, protist community structure was consistently different in the surface microlayer when compared with subsurface water. Here, also RP-A and Ku cluster in foci as seen through immunofluorescence.

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This has prevented further realization of the promise of cell transplantation as a platform technology. Transcoccigeal colpopexy with polyprolylene mesh with helper orifices for the treatment of posterior vaginal wall prolapse: anatomical and functional results Measles virus hemagglutinin mediates monocyte aggregation and increased adherence to measles-infected endothelial cells.

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All measured parameters varied significantly, but the amount of Hb per unit area of erythrocytes did not change over the nestling development of P. Borderline personality disorder in adolescents: evidence in support of the Childhood Interview for DSM-IV Borderline Personality Disorder in a sample of adolescent inpatients.

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Truncated binary data occurs when a group of individuals, who each have a binary response, are observed only if one or more of the individuals has a positive response. Electron-microscopic investigations of neuron subpopulations in paraventricular nuclei of rat hypothalamus demonstrated ultrastructural positive changes due to exposure of the stressed animals to impulse electric current (IEC).

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Whether it will be possible to improve treatment success by targeting these constituent processes more directly remains unexplored. Furthermore, increases in NAD(P)H amplitude, whether mediated by interferon-gamma or by an oscillating electric field, signals increased production of reactive oxygen metabolites. The relationships between the radionuclide alveolar integrity study and the pulmonary function test.

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MRI is helpful in diagnosing the trichilemmal cyst and useful in distinguishing cystic tumors on the median scalp from a cranial malformation, meningo- or encephalocele. Effect of hypocapnic anexemia on hypotensive action of histamine and acetylcholine It is also possible to measure the efficacy of topical preparations (cosmetics or drugs) designed for treating the various cutaneous aging marks. It is generally agreed that the goal of therapy in this syndrome is the consistent elevation of gastric pH levels above a certain value, often set at 4, in order to prevent the underlying mucosal damage from progressing to bleeding.

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The water transport mechanisms recently proposed by various researchers suggest that membranes composed of graphene oxide laminates could be regarded as an assembly of many tiny carbon nanotubes stacked together with attached functional groups as spacers. These results suggest that BMPR-IB mediates certain signals for GDF-5 after forming the heteromeric complex with BMPR-II or ActR-II. The distribution of the boron-10 compound, Na2 10B12H11SH, which is now in clinical use for boron neutron capture therapy for brain tumors, was studied topographically and quantitatively in rats using neutron-induced alpha-autoradiography. Intellectual impairment in children exposed to polychlorinated biphenyls in utero. Antitumor and antinociceptive approaches to control cancer pain.

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Patients undergoing TAVI with concomitant PD and/or TA require careful consideration to avoid the risk of APCs. Time-on-task effects were not only linear, but also of higher order and started after less than 1 min. Enhanced IPC by activation of pertussis toxin-sensitive and -insensitive G protein-coupled purinoceptors. This behavior of chick connexin-56 may explain previous observations of the unusual physiology of lens fiber gap junctions.

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Mice responded to these stimuli by making a nose-poke toward a computer monitor that was equipped with a touchscreen attachment for detecting responses. The gallbladder length, anteroposterior diameter, and transverse diameter have a linear relationship with gestational age between 15 weeks and 30 weeks of gestation, after which a plateau is observed. Perforation of the colon in the immunocompromised patient is a catastrophic and usually fatal event.

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The aspartate:2-oxoglutarate aminotransferase from the protozoon Trichomonas vaginalis exists as a mixture of sub-forms of identical Mr and amino acid composition, and of similar catalytic properties. Roentgenology and tuberculosis in the early part of XXth century The purpose of this study was to test whether exogenous growth factors influence the types of cells produced by progenitors at the retinal margin. Early morning reduction in ischemic threshold in patients with unstable angina and significant coronary disease. Inactivation of the p53 tumor suppressor gene via a novel Alu rearrangement.

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The results revealed six predominant IgE-binding bands, some of which appear in all the cultivars examined. Sudden incapacitations can affect a pilot and even a whole crew during a flight, preventing them from performing their task in complete safety. The improved possibility of an early diagnosis of ectopic pregnancy by use of serial quantitative beta-subunit human chorionic gonadotropin hormone levels together with transvaginal ultrasound has opened up options for conservative treatment.

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The effects of these ubiquinones on potentials measured in hypoxia were suppressed when the slices were incubated with a barbiturate solution. Somatostatin at concentrations of 10(-5) M and 10(-4) M significantly stimulated PGE2 and 6-keto-PGF1 alpha production by rat gastric epithelial cells but was not able to prevent damage induced by sodium taurocholate and indomethacin to rat gastric cells in monolayer culture.

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A logic model approach was used to frame program planning leading to the design of two low-cost interventions. The authors studied the effects of immunosuppressive peptide cyclosporin A (CsA) on cell fusion efficiency in cells persistently infected with measles virus (448-PI-Vero cells). Treatment of deficiency manifestations after early castration for cancer Dynamic curvature strongly affects wall shear rates in a coronary artery bifurcation model.

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Twenty-eight somatotrophinomas were placed into cell culture, and the in vitro effects of the PKC activator 12-O-tetradecanoylphorbol 13-acetate (TPA) and the PKC inhibitor staurosporine on basal and GH-releasing hormone (GHRH)-stimulated GH secretion were examined. The segment of vein (10 cm) proximal to the sapheno-femoral junction was studied. To prevent prosthetic joint infection, we previously reported the features of silver oxide-containing hydroxyapatite (Ag-HA), which was prepared by mixing silver (a metal with antimicrobial activity) with HA. We present a case of bilateral permanent visual field defect in a 30-year-old man after a massive hemorrhage caused by large vessel injury during a right nephrectomy.

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This is a longitudinal one-group design pilot study of a five-session ostomy self-care curriculum based on the Chronic Care Model to improve HRQOL and self-management for cancer survivors with ostomies. An infusion of lactate improved myocardial oxidative metabolism following ischemia and cardioplegia. In addition to causing DNA lesions, NO can directly interact with proteins by nitrosylation and nitosation reactions. Land cover change during a period of extensive landscape restoration in Ningxia Hui Autonomous Region, China. As there is substantive evidence for cross-organ sensitization in the pelvis can lead to co-morbidity of genitourinary and gastrointestinal dysfunctions, we also include how sympathetic dysfunction may play a role in a number of co-morbid chronic pain syndromes.

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We examined LTP following intra- or extracellular application of an NO scavenger, an inhibitor of NO synthase, and a membrane-impermeant NO donor that releases NO only upon photolysis with UV light. Using sequential iteration, the Bayesian formula is applicable to the calculation of a posteriori probabilities after multiple tests have been performed.

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Minimum referral data for clinical decision making and outcome criteria are defined. The cyclin dependent kinase inhibitor 2A (CDKN2A or P16) gene was cloned in this region and identified as a tumour suppressor gene. MAPK pathway was significantly up in late EECs, indicating drugs targeting this canonical pathway might be useful for treating advanced EECs.

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Endothelium-dependent relaxation in response to adenosine diphosphate is impaired under poor runoff conditions in the canine femoral artery. Circumcision status was self-reported, and the accuracy of the data was confirmed by physical examination at three study sites. melanogaster, all homoeo-box genes characterized to date are involved in major aspects of embryogenesis. Amyloids go genomic: insights regarding the sequence determinants of prion formation from genome-wide studies.

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To gain insight into the drug mode of action, we investigated here the effects of GKB per se on functional and signaling activities in human polymorphonuclear leukocytes (PMN). Asbestos lung fibre concentrations in South African chrysotile mine workers.

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Lower annual hospital volume of HD IL2 is associated with worse outcomes. The effect of the components of Bordetella pertussis lipopolysaccharides on Rauscher virus-induced leukosis in mice FKBP5 Messenger RNA Increases After Adolescence in Human Dorsolateral Prefrontal Cortex.

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Depending on the dosage, sodium salicylate repeatedly increased the corticosterone-binding function of Type III glucocorticoid receptors. Hypoplastic right ventricle with eosinophilic endomyocarditis and patent foramen ovale.

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From our investigations we conclude that there is no direct effect of streptococcal erythrogenic toxins on neopterin production by monocytic cells. Morphometric analysis of noninvasively assessed bone biopsies: comparison of high-resolution computed tomography and histologic sections.

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Here, we report that treatment with 100-microM baicalein caused an almost complete inhibition of cell proliferation after 5 days of incubation. Testing with low strain rate at 37 degrees C accentuated the differences between these two materials and the zinc phosphate cement. This study included 22 patients in whom the thyroid was incidentally exposed to therapeutic doses of radiation.

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Vaccinia virus (VV) protein A39R has amino acid similarity to the extracellular domain of a glycosylphosphatidylinositol-linked cell surface semaphorin (SEMA7A/CDw108) that has an immunological expression profile and binding properties, thereby implicating A39R as an immunomodulator. This chapter describes the development and evolution of the interview and offers guidelines for operationalization of substance abuse and dependence criteria. The additional finding that the activity of the two mutants is fully restored upon association with the regulatory beta subunit, in conjunction with the observation that synthetic peptides reproducing the N-terminal segment (1-30) and the activation loop (175-201) of CK2alpha counteract the functional effects of the C-terminal domain of the beta subunit, is consistent with a mechanism of activation of CK2 where the N-terminal domain of alpha and the C-terminal domain of beta play interchangeable roles.

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The optimal clinical reading measurement recommended for the ear lobe TcPCO(2) measurement ranges between minute 12 and 14. Thrombosis and coagulation are novel mechanisms recently associated with cancer. Dextrans had no effect on fracture healing whereas heparin induced an increased chondroid reaction in the callus.