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The latter pathway can bypass primase deficiencies by allowing retrograde DNA synthesis without Okazaki pieces. Validity and reliability of the Persian version of spatial hearing questionnaire. New trails in transplantation: how to exploit the potential of sirolimus in clinical transplantation. Phase II study of concurrent transarterial chemoembolization and sorafenib in patients with unresectable hepatocellular carcinoma.

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Transcriptome analysis revealed that expression of T3SS genes, including master regulator ExsA, was defective in a fis::Tn mutant. The mixture of all these compounds produced during the lactic acid fermentation in suitable proportions is what gives butter its characteristic flavor. Performance of the model was tested by evaluating accuracy of mortality predictions obtained from pre-ICU PRISM scores in a separate validation set of patients. The effect of heat on the nutritive value of milk proteins as influenced by water and fat. Particular emphasis is given to the presentation of the diseases as they may appear after use in a biowarfare scenario.

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The cell corpse material is strongly acidified soon after engulfment and persists in the phagocytic cell for several hours. Insulin action measured in cultured fibroblasts was similar in NC and PCOS cells. Furthermore, there is conflicting evidence concerning the role played by yeast, pseudohyphal, and hyphal forms of C. Tube tamponade: potential pitfall in angiography of arterial hemorrhage associated with percutaneous drainage catheters.

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Twenty patients with chronic duodenal ulcer (duodenal ulcer group) and 20 age-matched normal adults (N group). Symptomatology of pure invagination of the small intestine with special reference to a case of malignant carcinoid of the jejunum The incidence of thyroid abnormalities in adults irradiated for lymphoma. Effects of TA-0910 (1-methyl-(S)-4,5-dihydroorotyl-L-histidyl-L-prolinamide), a new thyrotropin releasing hormone (TRH) analog, on spinal reflex potentials and flexor reflexes were compared with those of TRH in C1-spinal rats.

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Host membrane trafficking for conveyance of intracellular oral pathogens. 4 Atropine (1 micrograms/kg) diminished the secretory responses to methacholine as much as clonidine (10 micrograms/kg). Experimentally produced pulmonary vascular changes: their relationship to similar changes found in congenital and acquired heart disease. There was a differential distribution of ANP and endothelin-1 (ET-1), with a higher ANP concentration in cell extracts and a higher ET-1 concentration in cell culture media. These gross and microscopic findings, as well as the peripheral eosinophilia and clinical response while oral steroids were administered, are all characteristics of the recently described entity called eosinophilic fasciitis.

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Laminar closure rates in patients with cervical myelopathies treated with either open-door laminoplasty with reattachment of spinous processes and extensor musculature or Hirabayashi open-door laminoplasty: a case-control study. Our study suggests that PA is effective for pain reduction and functional improvement in patients with chronic radicular pain caused by LFSS. The side chain of the residue (B) is then replaced by a suitable conformer of a residue that is electrostatically complementary to the residue (A) to enhance local interactions and hence the stability of the protein.

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No delayed procedure-related complication was seen during the survival period of our patients. KRAS mutations in colorectal cancer primary tumors predict resistance to anti-Epidermal Growth Factor Receptor (EGFR) monoclonal antibody therapy in patients with metastatic colorectal cancer, and thus represent a true indicator of EGFR pathway activation status.

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In the group with orthostatic hypotension, compression improved the symptoms without correcting the blood pressure readings. Follow-up results of surgery of acquired heart valve diseases and their improvement

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The sniff nasal inspiratory pressure (SNIP) was measured through a plug occluding one nostril during sniffs performed through the contralateral nostril. Uncloned pools of NIH 3T3 cells producing the pRB binding target E2F-1, E2F-2, or E2F-3 grew in semisolid medium.

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The second lesion manifested definitely low signals on both T1- and proton density-weighted images, implying a cystic lesion. Moreover, the outcome of the MC57 and MM4.17 epitopes localization experiments, obtained through the use of phage-displayed peptide libraries, represent an additional challenge to the classical 12-transmembrane domain model of P-glycoprotein, since they agree with the novel topography of the molecule (10-transmembrane domain), which was recently proposed on the basis of biochemical and expression studies. Since very viscous fluids are usually non-Newtonian, an extension of the theory to include non-Newtonian effects is needed.

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Seroprevalence of Helicobacter pylori in residents of a hospital for people with severe learning difficulties. These results contribute to a better knowledge of fasting, subfeeding, and refeeding processes in birds and can be added to a recent study about fasting in gulls.

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The authors characterized clinical, laboratory, and pathologic features of the disease and sought linkage to previously recognized ataxia loci. Mechanisms of differential radioresistance of mammalian cells cultured in vitro The article presents a brief description of the sources for the study of the history of malaria in Italy that are held at the Rockefeller Archive Center. We have used high-pressure freezing techniques to study exocytosis in rat anterior pituitary cells. Pyrimidinylimidazole inhibitors of CSBP/p38 kinase demonstrating decreased inhibition of hepatic cytochrome P450 enzymes.

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Four individuals had had multiple episodes of infection, 3 had only incidental infections, and 14 never had any serious infection. During surgery, an intestinal granulomatous inflammation was observed adhered to the hernial sac. The randomized SECURITY (Second-Generation Drug-Eluting Stent Implantation Followed by Six- Versus Twelve-Month Dual Antiplatelet Therapy) trial showed the non-inferiority of 6 vs. Critical issues in setting micronutrient recommendations for pregnant women: an insight.

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Most importantly, adult RGC depend completely upon the presence of a preformed layer of neonatal cortical astrocytes, whereas RGC from neonatal retinae are supported by indigenous retinal glia which spread and proliferate to form a monolayer of cells upon which RGC regrow processes. Premature rabbits, delivered at 28 days of gestation, were treated intratracheally with antioxidant-surfactant liposomes, surfactant liposomes without antioxidant enzymes, or air placebo at birth and exposed to hyperoxia for 24 h. A single PO dose of dexamethasone can be effectively and safely used for the outpatient treatment of moderate croup. Immunological functions of hyaluronan and its receptors in the lymphatics.

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In the present study we demonstrate for the first time the existence of a visual peripersonal space centred on the face in humans. An evaluation of the results of media and educational campaigns designed to shorten the time taken by patients with acute myocardial infarction to decide to go to hospital. Many leaders in our specialty worldwide have directly or indirectly trained in Toronto. They are divided into three subtypes (alpha, beta or delta, and gamma) and are involved in lipid and glucose homeostasis and in the control of inflammation. African-Americans have a higher prevalence of heart failure than whites, present with heart failure at younger ages, and heart failure in them is less likely to be due to coronary heart disease.

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We have used electron microscopy and single-particle image analysis to examine T7 gp4, and have determined that the primase active site is located on the outside of the hexameric ring, and therefore provide direct structural support for this model. However, their combination in such a small, biologically interacting sea exacerbates the overall deterioration. Regional and chronological differences of urogenital cancer deaths in Japan The lipid bilayer of the myelin membrane of the central nervous system (CNS) and the peripheral nervous system (PNS) contains the oligodendrocyte- and Schwann cell-specific glycosphingolipids galactocerebrosides (GalC) and GalC-derived sulfatides (sGalC).

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Integrated genome-scale analysis of the transcriptional regulatory landscape in a blood stem/progenitor cell model. The results suggest that the two binding sites with a similar triple-helical conformation have distinctive ways of interacting with heparin, which must relate to small differences in the consensus sequence (GRKGR vs GKRGK) and in the surrounding basic residues. An atomistic approach to conduction between nanoelectrodes through a single molecule.

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The least-squares method is frequently used to calculate the slope and intercept of the best line through a set of data points. Both immunocytochemical and live imaging analyses showed that newly formed microtubules predominated at the distal end of axons and dendrites, suggesting a common mechanism that incorporates increased microtubule polymerization at growing process tips. A 17-year-old woman developed a unilateral facial paralysis with vesicles in the left ear and in the throat. Surgical correction of total anomalous pulmonary venous drainage in infancy can be performed at low risk with good results.

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Detection of silent ischemia adds to the prognostic value of coronary anatomy and left ventricular function in predicting outcome in unstable angina patients. A twin registry study of familial and individual risk factors for trauma exposure and posttraumatic stress disorder. Analogues of glucose labeled with 123 iodine in positions 1, 2 or 3 have been synthesized.

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The greatest histologic improvement was observed in the group treated with the combination of RC-160 and D-Trp-6-LH-RH. Gender governs the relationship between exercise intensity and growth hormone release in young adults. A series of cFMS-transfected HL-60 sublines with progressively higher cell surface FMS expression was derived by flow cytometric cell sorting.

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The different physicochemical properties of the lipids found in biological membranes allow antimicrobial peptides to discriminate between bacterial and mammalian cell membranes. We discuss the analysis of small RNAs and the integration of RNA-seq with other functional genomics techniques. The use of longer lists either eliminated (Experiment 1) or greatly reduced (Experiment 2) the NOLAP advantage. Finally, expression of a dominant-negative form of nNOS prevents both RC-160-induced p27 up-regulation and cell proliferation inhibition. In vitro binding studies with two hypericum perforatum extracts--hyperforin, hypericin and biapigenin--on 5-HT6, 5-HT7, GABA(A)/benzodiazepine, sigma, NPY-Y1/Y2 receptors and dopamine transporters.

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Mattoni, NUS Corporation) on the Biosatellite II mission significant effects of space flight were found on both growth rate and the induction of prophage. Nevertheless, free astaxanthin levels appear insufficient to balance the amounts of the esterified form, scored at the end of the endotrophic period. Vascular structures were supposed to be the invaded native mesenteric vessels within the infiltrating inflammatory mass lesions. However, the presence of these cells is not a sufficient parameter to predict growing metastases in the majority of patients, suggesting that epithelial cells in the BM of breast cancer patients at the time of surgery have limited metastatic potential.

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Because the response rate to the survey was low, these findings may not be completely representative of the targeted group of physicians. Incidence of thigh pain after uncemented total hip arthroplasty as a function of femoral stem size.

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The parasite is now widespread in urban and suburban areas in central Europe. Cervical spine fractures in the elderly: morbidity and mortality after operative treatment. Quantitative trait locus analysis for pod- and kernel-related traits in the cultivated peanut (Arachis hypogaea L.). Tumor dissemination after radiofrequency ablation of hepatocellular carcinoma.

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Protein substrate polyacrylamide gel electrophoresis revealed several bands with proteolytic activity at apparent molecular masses of 200, 100, and 50 kDa. Met receptor tyrosine kinase: enhanced signaling through adapter proteins. By revealing the neural markers of the concreteness effect, our study contributes to the understanding of the neurogenesis of verbal semantic knowledge impairments and the incidence of these impairments in clinical populations. Neoadjuvant therapy primarily consists of either chemotherapy, radiation therapy, or a combination of the two.

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Our studies suggest that 14-3-3 binding to HDAC5 is required for CaMK-dependent disruption of MEF2-HDAC complexes and nuclear export of HDAC5, and implicate 14-3-3 as a signal-dependent regulator of muscle cell differentiation. To evaluate health-related quality of life (HRQL) and medication satisfaction after switching from a stable dose of oral extended-release methylphenidate (ER-MPH) to methylphenidate transdermal system (MTS) via a dose-transition schedule in children with attention-deficit/hyperactivity disorder (ADHD).

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Northern blot analysis with the TCR gamma cDNA probe revealed 1.9-kb transcripts in the thymus, spleen, and a gamma delta T-cell line, but not in B or alpha beta T-cell lines. Cortical projection topography of the human splenium: hemispheric asymmetry and individual differences. She continued to have intermittent symptoms of chest pain, back pain, and shortness of breath for the next 1.5 months.

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Report of the Commission of Revision of the Bertillon Classification of Causes of Death. Caries experience and the mineral content of plaque in a primitive population in New Guinea. Clinical application of transorotracheal tube tracheal insufflation of oxygen in patients undergoing simple video-assisted thoracoscopic surgery. A significant inhibition of prolactin (PRL) secretion was observed for both drugs within 12 h after treatment, and the inhibitory effects of CG and BC were antagonized by sulpiride or haloperidol.

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Erectile dysfunction--the effect of sending a questionnaire to patients on consultations with their family doctor. Investigation of the effect of naringenin on oxidative stress-related alterations in testis of hydrogen peroxide-administered rats. The TMP gene was found to be highly expressed in brain tumor cells but not in normal brain. Importantly, RIP recruitment to DAI is inhibited by the RHIM-containing murine cytomegalovirus (MCMV) protein M45.

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EV71 virus-like particle (VLP) was produced in yeast expression system by the co-expression of four EV71 structural proteins VP1-VP4. alpha1,2-Fucosylated and beta-N-acetylgalactosaminylated prostate-specific antigen as an efficient marker of prostatic cancer.

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Some ICP genes have been used for bioengineered crop protection, resulting in transgenic crop plants with excellent insect protection. Analogs of farnesyl diphosphate alter CaaX substrate specificity and reactions rates of protein farnesyltransferase. Analysis of surgical complications after 397 hepatic transplantations. A case of surgically treated hypertrophic obstructive cardiomyopathy suffering from angina pectoris during hemodialysis We present two studies exploring the dimensionality of these sources within the context of career-relevant mathematics activities.

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Study of the number of roots and canals in Senegalese first permanent mandibular molars. While several mechanisms were proposed to account for these effects, limited information exists regarding GC actions in sensory areas of the spinal cord. Massive ovarian edema can be managed conservatively and blood flow in the pedicle of the ovary is detected by color and pulsed wave Doppler examination.

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The treatment of tuberculous patients with electroshock therapy. Medical services have long been an integral part of the military and warfare. The antiserum demonstrated not only immunocytochemical reaction with some other arthropod species, but also stained many areas of the rat CNS, certain islet cells of the pancreas, and some anterior pituitary cells.

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As for the protocol of temperature, we decided that rapid change was the large temperature gradient of more than 0.5 degree C/min, and slow change was the small gradient of less than 0.3 degree C/min. Midterm ultrasound biomicroscopy findings in eyes with successful viscocanalostomy. Effects of left recurrent laryngeal neurectomy, prosthetic laryngoplasty, and subtotal arytenoidectomy on upper airway pressure during maximal exertion. A case of chronic bromvalerylurea intoxication with episodic neurological manifestations such as optic neuropathy ophthalmoplegia and ataxia

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Randomized prospective comparison of fertilization in sibling oocytes. Identification of an arginine vasopressin-like diuretic hormone from Locusta migratoria. Deficiencies of Cu, Se, vitamin E and Co in cattle reduce the ability of isolated neutrophils to kill yeast and/or bacteria. Acute traumatic haemorrhagic shock and transfusion: the French army policy

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Improvement of the results of organ transplantation in France during the past decade. Effect of thiol oxidation and thiol export from erythrocytes on determination of redox status of homocysteine and other thiols in plasma from healthy subjects and patients with cerebral infarction. Thus, at low shear rates and high specific surface conditions, the degree of hemolysis was found to be minimal while particulate-matter formation was high. We previously demonstrated MORF/cMORF pretargeting of human islets and betalox 5 cells (a human beta cell line) transplanted subcutaneously in mice with the anti-human islet antibody, HPi1. The amino acid contents of strains bearing the different constructs were analyzed both under repression and induction conditions.

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Subsequently it was found that the mold elaborated a substance, now designated helenine, which is therapeutically effective against Columbia SK encephalomyelitis virus infections in mice. The complex consists of three invariable components--Cul1, Skp1, Rbx1 and F-box protein, which determines the substrate specificity.

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Aim of the study was the evaluation of the fracture pattern and the benefit of cross-sectional imaging in classification of Triplane-fractures. As a means of circumventing this technical difficulty, we have developed an organ culture of the mouse cochlea and here we describe the receptor potentials generated by the hair cells in response to direct displacement of their stereocilia. This work has broad implications, as roughly one-third of the US population will sustain a mild TBI during their lifetime.

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Maternal exposure to caffeine induces also long-term consequences on sleep, locomotion, learning abilities, emotivity, and anxiety in rat offspring, whereas in humans, more studies are needed to ascertain long-term behavioral effects of caffeine ingestion by pregnant mothers. High velocity sedimentation in sucrose gradient demonstrated that Pub1 was preferentially associated with heavy polysomes enriched with terminating ribosomes.