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The use of central venous catheters in paediatric oncology--a cautionary tale. Our major T cell thyroiditogenic epitope contains a T4 residue which accounts for over half the molecular weight of the peptide. In Experiment 1, subjects grasped large targets in the presence of both large and small 3-D distractors and their corresponding 2-D photographs. Effects of tunicamycin on growth hormone binding in rat adipocytes.

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The persistent expression of the Dfd protein requires an endogenous copy of the Dfd gene, and we show that the expression of the endogenous copy can be induced by hsDfd expression. Cryoablation and liver resection for noncolorectal liver metastases. Economic evaluation of HIV testing among intravenous drug users. The role of the autonomic nervous system in the regulation of thyroid activity

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Also, miR398 up-regulation is inversely correlated with the down-regulation of copper superoxide dismutase, CSD1, during water deficit. During saline infusion, all parameters remained unchanged for 90 min. Larger forms of gynecomastia with significant ptosis pose a challenge to the plastic surgeon with respect to relocation of the nipples on the chest wall. Clinical success (resolution of diarrhea within 24 hr) and bacteriological success (cessation of excretion of Vibrio cholerae by day 3). Similarly, condiments like coriander, black cumin, turmeric, garlic, and ginger are recognized for constituents like linalool, thymoquinones, curcumin, allicin, and geranial respectively.

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It is important to remember that PCA will continue to develop in the future and new techniques are being devised. The results indicate that a variety of different neural rhythms are involved in the perception of long-range apparent motion. Borrelia japonica in nature: genotypic identification of spirochetes isolated from Japanese small mammals.

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Telomerase genes hTR and hTRT in 50 cases of mammary hyperplasia (the cases included 6 benign hyperplasia, 9 mild atypical hyperplasia, 12 medium atypical hyperplasia, 23 severe atypical hyperplasia) and 26 cases of breast carcinoma were detected by in situ hybridization. dUTPase from the retrovirus equine infectious anemia virus: high-level expression in Escherichia coli and purification. Many articles have evaluated the success rates of fixed prostheses supported by osseointegrated implants, indicating high rates of success for prostheses 5-10 years in function. Mitochondria as a target of cadmium nephrotoxicity: induction of swelling and cytochrome C release. In this study we introduced the transmembrane domain of diphtheria toxin into a DNA-polycation conjugate complex in an effort to increase gene transfer by membrane perturbation.

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Serum level of phosphate is regulated by the kidney, especially proximal tubule. Interindividual variability in catalytic activity and immunoreactivity of three major human liver cytochrome P450 isozymes. The prosthesis valves were replaced at each changeover and were assessed for wet weight of removable biofilm, yeast numbers in removable biofilm, valve leakage, and valve damage.

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The evidence for an effect of melatonin on breast cancer in experimental animals is strong, but the evidence in humans is scant and difficult to gather. Atomic structure and specificity of bacterial periplasmic receptors for active transport and chemotaxis: variation of common themes. However, we show that 1,25-(OH)2D3 treatment of primary osteoblasts abolishes the binding of OSF2, an osteoblast-specific activator of transcription that binds to OSE2, a critical osteoblast-specific cis-acting element present in OG1 and OG2 promoters. Reactivation of hepatitis B virus replication accompanied by acute hepatitis in patients receiving highly active antiretroviral therapy. Fourteen athletes aged 17-33 (mean 23) were treated non-operatively.

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Many aspects of the RSV life cycle have been studied, but the mechanisms that drive RSV assembly at the cell surface are not well understood. Diagnostic and therapeutic laparoscopy of the nonpalpable testis. Belief in hexing or root work is still alive today and should be inquired about in patients with unusual symptoms and an appropriate cultural background.

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Multiconjugate adaptive optics (MCAO) is a technique for correcting turbulence-induced phase distortions in three dimensions instead of two, thereby greatly expanding the corrected field of view of an adaptive optics system. Four-year outcome data for 400 laparoscopic cholecystectomy patients: recognition of persistent symptoms.

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Effect of physical activity on exo- and endogenous hyperlipemias However, such treatment is currently available to few primary care patients. In a level 1 university trauma center, an explorative randomized controlled study was performed to compare soft tissue damage and functional outcome after antegrade femoral nailing through a trochanteric fossa (also known as piriform fossa) entry point to a greater trochanter entry point in patients with a femoral shaft fracture. Staffing decisions should be made on the basis of more precise information about treatment requirements, not just staffing ratios.

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Angiotensin converting enzyme gene polymorphism predicts blood pressure response to angiotensin II receptor type 1 antagonist treatment in hypertensive patients. We report Stimulated Emission Depletion (STED) imaging of green fluorescent nanodiamonds containing Nitrogen-acancy-Nitrogen (NVN) centers with a resolution of 70 nm using a commercial microscope.

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Identification of Mac-2-binding protein as a putative marker of neuroendocrine tumors from the analysis of cell line secretomes. Granulocyte phagocytosis was directly induced by FcgammaRI and FcgammaRII but not by FcgammaRIIIb. The present study demonstrated a relationship between wakefulness-promoting cytokines and objectively measured EEG vigilance as an indicator for brain arousal. SAP, the gene that is altered or absent in the X-linked lymphoproliferative syndrome (XLP), encodes a small protein that comprises a single SH2 domain and binds to the cell-surface protein SLAM which is present on activated or memory T and B cells. Our data suggest that the local microenvironment of distinct brain regions is critical to determine virus permissiveness.

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Does memory constrain utilization of top-down information in spoken word recognition? This modified alpha2-macroglobulin maintains its ability to bind to the alpha2-macroglobulin receptor, and was shown to introduce a luciferase reporter gene plasmid into HepG2 human hepatoma cells in vitro. To evaluate the efficacy of low-energy selective laser trabeculoplasty (SLT) in patients with primary open-angle glaucoma (POAG) and ocular hypertension (OHT) following up to one year.

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Here, five HCMV genes were studied to investigate the existence of recombination events in clinical strains ex vivo. The dilatation of the arteries induced by these agents was inhibited by the H1-antagonist chlorpheniramine, but not by the H2-antagonist cimetidine. A treatment which has a simple regimen with fewer injections, and/or the need for less planning, and that causes weight loss or less weight gain, compared with other treatments, will have a positive impact on HRQoL. It had no significant effect on effective refractory period and electrical threshold for excitation, but decreased contractile force.

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Spatial maps representing the likelihood of tumor infiltration and future early recurrence were compared with regions of recurrence on postresection follow-up studies with pathology confirmation. MxA is a reliable marker of IFNalpha release and its level was significantly enhanced in SIDS reflecting the release of IFNalpha in response to viral infection. Combination of stromal-derived factor-1alpha and vascular endothelial growth factor gene-modified endothelial progenitor cells is more effective for ischemic neovascularization.

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We identified only a few in the caudal part of the DMV and no TH-IR cells at all in its rostral portion. Tiapamil, a new calcium antagonist, was evaluated for its antihypertensive and metabolic effects in a long-term (58 weeks) drug trial in 20 adult outpatient mild to moderately hypertensive subjects. The intrarenal arterial infusion of SNP, in a dose (1 mu g/kg/min) that does not affect renal hemodynamics and urine formation at the basal level, significantly attenuated the RNS-induced decreases in UF, UNa V and FENa. Experiments also showed that the droplet size and the spray monodispersity were independent of the electrode configuration, as long as the electrospray was operated at the onset voltage condition, that is defined as the minimum voltage at which the cone-jet mode was established.

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Occurrence and sequence complexity of polyadenylated RNA in squid axoplasm. We report the clinical features of 7 cases of coagulase-negative staphylococcal native valve endocarditis (CNS-NVE) seen at 1 institution with a large cardiovascular referral base over a 10-month period. A protein of similar electrophoretic mobility was detected from the isolated fimbrial antigen. An impedance camera for spatially specific measurements of the thorax.

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We estimate a series of discrete-time logit models with duration dependence to obtain transition probabilities among Medicaid, privately insured, and uninsured spells. The 2-D apoB profile was composed of a number of trypsin-generated fragments having a molecular mass between 10 and 188 kDa and a wide spectrum of isoelectric points. This behavior was observed in HeLa cells, containing endogenous receptors, or in CV-1 cells, containing almost no endogenous receptor, with either homologous or heterologous receptors. Eight regional hospitals were surveyed to obtain information on the use of histamine H2-receptor antagonists.

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The findings suggest that when learning maps people use a multimodal learning strategy, utilising resources from all components of working memory. This study showed an increase of soluble TM levels in sera from patients with diabetic nephropathy. In a rat model of pneumonia, the effects of acute intoxication were monitored for lung chemokine responses, neutrophil recruitment, and bactericidal activity. A nonmyristylated form of Nef associated with viral particles with considerably lower efficiency, suggesting that Nef gains access into nascent virions primarily as a consequence of its affinity for membranes. Thus, the physical interaction reported here appears to be physiologically significant.

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Loss of heterozygosity on chromosomes 3, 13, and 17 in small-cell carcinoma and on chromosome 3 in adenocarcinoma of the lung. Interactive effects of denervation and malnutrition on diaphragm structure and function. In the UK, these will often be general internal medicine consultant geriatricians, while the younger patients are seen by consultants practising general internal medicine in addition to one of the specialties.

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Reassurance and clear information about prognosis are important and emotional support must be offered throughout the investigation and subsequent pregnancy. Double minute chromosomes or double minutes (DMs) are cytogenetic hallmarks of extrachromosomal genomic amplification and play a critical role in tumorigenesis. Moreover, Westerners experience high arousal emotions more than low arousal emotions.

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We have isolated a novel mouse gene, Dll1 (delta-like gene 1), which maps to the mouse t-complex and whose deduced amino acid sequence strongly suggests that Dll1 represents a mammalian gene closely related to Drosophila Delta. However, since similar degrees of EPSP potentiation were observed following blockade of spike activity by intracellular QX-314, spike activity was not the primary conditioning factor. coli adherence factor was identified significantly more frequently in cases (10) than in controls (0). The results of this study may have importance for the design of the next generation of speech processors. Media reports about a consumer guide to coronary artery bypass graft surgery.

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Pre-treatment with genistein or equol at doses of 0.01-100 micromol/l significantly protected sperm DNA against oxidative damage. Optical isomers of cysteine in the prevention of leukopenia induced by nitrogen mustard. A large-scale mitochondrial DNA deletion causing progressive ataxia. One patient developed hypertension but there were no other complications. The factor, therefore, maximizes the ability of the DNA polymerase to synthesize small fragments, which is compatible with DNA repair or lagging strand DNA replication.

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A gene transfer method for the study of chimerism derived from donor bone marrow in organ transplant recipients. Density has only second-order effects on the pattern of oldest-old mortality over the range of densities studied here.

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Lens expulsion into sub-conjunctival space following peribulbar anaesthesia. After induction chemotherapy the dog became severely hypocalcaemic and showed signs of weakness, muscle fasciculation and facial pruritus. The insulin-loaded polymeric nanoparticles based on the pentablock copolymers allow sustained release of insulin in vitro, and PEI can enhance sustained drug release and reduce burst drug release. Relationship between glomerular mesangial cell proliferation and amyloid deposition as seen by ultrastructural and morphometric analysis in experimental kala-azar of the hamster. One prominent example of high ecological relevance is the endosymbiosis between dinoflagellate algae of the genus Symbiodinium and reef-building corals, which typically acquire symbionts anew each generation during larval stages.

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Other features of the system are discussed and an assessment of its operational reliability is given. We report the case of a 13-month-old boy with meningitis that was unresponsive to antimicrobial therapy. The catalyst exhibits remarkable activity for both the oxygen evolution reaction (OER) and hydrogen evolution reaction (HER) in alkaline media, delivering a current density of 10 mA cm(-2) at an overpotential of 281 mV for OER and 95 mV for HER.

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This surprising migration of perivascular cells toward decaying neurons was additionally tested and confirmed by intracerebroventricular application of FG prior to resection of the facial nerve Providing evidence for neuronophagia by ED2-positive cells, our results strongly support the hypothesis that the latter are the APC (antigen presenting cells) of the CNS. If this is the case, the increases in mRNA levels must be translated into increased beta III-tubulin protein levels and subsequently modify the axonal cytoskeleton via axonal transport mechanisms. Statistical parametric maps and conventional regions of interest analysis were used for estimating rCBF differences.

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The results show that AGRMET data produces larger spatial decorrelation compared to in situ based soil moisture data. The specificity of antisera against Bordetella pertussis examined by bacterial agglutination. Results will also be presented at national and international pharmacoepidemiology and health policy forums such that other jurisdictions have guidance to adapt this methodology. The majority of excitatory synapses in the mammalian CNS (central nervous system) are formed on dendritic spines, and spine morphology and distribution are critical for synaptic transmission, synaptic integration and plasticity. Reticulin fibres display a distinct argyrophilia when studied by means of silver impregnation techniques, and show up as a thin meshwork of weakly birefringent, greenish fibres when examined with the aid of the Picrosirius-polarization method.

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This study highlights the lack of efficacy of national tuberculosis control programs in the country. A case of 40 years old female with C2 vertebrae destruction caused by multiple myeloma treated surgically has been presented.

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Inoue-Melnick virus (IMV) was isolated from the cerebrospinal fluid of patients with chronic neurologic disorders. The ICE images showed the transseptal puncture (Brokenbrough) needle as a point casting an acoustic shadow. In situ hybridization demonstrated that PrP mRNA was localized in and around the fibrous septa of carbon tetrachloride (CCl4)-treated liver. In particular, it is a challenge to predict beta-sheet structures since they range over several discontinuous regions in an amino acid sequence. This was a prospective study on patients with a diagnosis of aneurysmal SAH, 72 hours after the initial event.

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Surgical resection with preservation of the sphincters is the recommended treatment. Profluorescent protease substrates: intramolecular dimers described by the exciton model. Hya, the murine locus controlling H-Y expression, has been localized to delta Sxrb, a deletion interval of the short arm of the Y chromosome. These results suggest that the gene cluster is unique to serotype a and is essential to the synthesis of the SPA.

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When overexpressed in C2C12 cells, Hes6 impairs normal differentiation, causing a decrease in the induction of the cyclin-dependent kinase inhibitor, p21(Cip1), and an increase in the number of cells that can be recruited back into the cell cycle after differentiation in culture. In an attempt to elucidate the underlying mechanisms leading to this alteration in responsiveness of the locus coeruleus, the sensitivity of noradrenergic neurons of the locus coeruleus to the transmitter candidates, epinephrine and glutamate, was investigated in DOCA-prehypertensive (3 days post-DOCA), DOCA chronic hypertensive (6-8 weeks post-DOCA) and control rats using conventional microiontophoretic and single cell recording techniques. The disagreement may indicate that differences between crystal and solution structures exist with altered accessibilities of the atoms under consideration. neurocysticercosis (NCC) prevalence is increasing throughout the United States mainly because of immigration from Latin America. Thermoluminescence dosimetry systems will replace the existing photographic dosimetry system for the individual monitoring with the joint support of IAEA and GAEC.

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Bioluminescent leukemic cells (HL60-Luc) were used to compare the colocalization of the fluorescent mAb with these cells. Although, the risk of transmission of HIV and other blood borne pathogen may account for a very small proportion, yet the potential for such transmission always exists.