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The second type (Flounder 2) is related to sequences reported from Atlantic salmon, cod, and the Antarctic fish, Paranotothenia magellanica. Aminoglycoside clearance is a good estimate of creatinine clearance in intensive care unit patients. To investigate whether MK plays a role in breast cancer, we examined MK mRNA expression in N-nitroso-N-methylurea-induced rat mammary tumors at various stages of tumor progression, including hormone independence and distant metastasis.

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We seek to determine whether ropivacaine cervical paraspinal injections compared with normal saline solution injections provide headache relief to pediatric patients that is sufficient for emergency department (ED) discharge. We report twelve cases of minimally invasive coronary artery bypass grafting via small laparotomy using right gastroepiploic artery (RGEA) to the right coronary artery. In relation to the stress distribution in the photoelastic analysis, the fringes were concentrated near the osteotomy and to the lower part of the mandible in the linear 90 degrees -screw system and reversed L arrangement. In these cases only the temperature experienced during embryonic development had a significant permanent effect on flight.

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Finally, renal angiomyolipomas from patients with tuberous sclerosis complex contain both adipose and smooth muscle-like components with activated mTORC1 signaling and elevated PPARgamma expression. The beneficial effect of nasal breathing on exercise-induced bronchoconstriction.

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Discovery of the causative gene for DRPLA has made it possible to investigate molecular mechanisms of neurodegeneration caused by expanded polyglutamine stretches. Mean hearing thresholds obtained using these 4 different setups varied by 5.6dB, 3.7dB and 4dB at 200Hz, 500Hz and 1000Hz, respectively. Difficulties in anticoagulation management during coadministration of warfarin and rifampin. This difference was not attributable to baseline TSH and cortisol levels or to neuroleptic treatment.

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pharaonis, SRII (NpSRII) mediates photorepellent responses through its transducer protein, NpHtrII. They have found a use as growth promoters to improve meat-to-fat ratios in cattle but they are not authorized for use in the European Union.

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Dipyridamole 201Tl myocardial scintigraphy was performed preoperatively in 93 consecutive patients with diabetes undergoing peripheral vascular procedures. P450 UT-8 hydroxylated arachidonic acid only at the omega-position. This study reports the first development of a fluorescently labeled filamin. Weight reduction in bulimia nervosa by abuse of thyroid hormones

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Clinical signs were observed in 41 per cent of the pigs on ante-mortem inspection. Pseudohomothallism and evolution of the mating-type chromosome in Neurospora tetrasperma. To evaluate the role of magnetic resonance imaging (MRI) and single photon emission computed tomography (SPECT) in the detection of sacroiliitis in patients with clinical features of inflammatory back disease but without conventional radiographic changes.

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Household exposure to passive cigarette smoking and serum micronutrient concentrations. Regeneration of brainstem-spinal axons after lesion and immunological disruption of myelin in adult rat. Usually these processes are used to support clients with chronic or complex care needs.

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Perioperative morbidity and mortality, estimated blood loss, transfusion requirements, natural history of the excluded aneurysm sac, and long-term survival were all assessed. Evaluation of a hepatitis B vaccination program in Taiwan: impact on hepatocellular carcinoma development. It was led by a family therapist who was a member of a psychosocial services team.

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Body dimension (height, body mass), aerobic power (treadmill to exhaustion), forced vital capacity (FVC), one second forced expiratory volume (FEV1.0). Postneonatal mortality decreased from 9.4 per 1000 live births to 5.5 per 1000 live births for males, and from 8.3 to 5.0 for females. The study of reverse evolution from resistant to susceptible phenotypes can reveal constraints on biological evolution, a topic for which evolutionary theory has relatively few general principles.

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In the third case, orofacial dyskinesia that had remitted after withdrawal of sertraline and paroxetine and reappeared with fluoxetine was still present eight months after fluoxetine was withdrawn. These efforts will require primary care physicians to concentrate their efforts on education, negotiation, and enhanced trust in their patient relationships. While technical and regulatory issues were not major impediments, business and marketing concerns contributed to a decision to halt development of the test. 13 cases of seminoma of the testes were investigated in detail by means of light microscopy using paraffin and semithin sections.

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Catalytic and immunochemical characterization of cytochrome P450 isozyme induction in dog liver. Evaluation of the performance of immobilized penicillin G acylase using active-site titration.

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Maltose phosphorylase (MP) is a dimeric enzyme that catalyzes the conversion of maltose and inorganic phosphate into beta-D-glucose-1-phosphate and glucose without requiring any cofactors, such as pyridoxal phosphate. The use of rt-PA had no influence on the healing process of either type of graft. In light of the external membrane-bound location, the involvement of Com70 at the early stage of protein translocation was investigated using a combination of in vitro binding assays, chemical cross-linking, and coimmunoprecipitation. Association of alpha 1 -antitrypsin deficiency and primary pulmonary emphysema as determined by the method of radial immunoduffusion. The authors necessitate general efforts to maintain balanced nutrition with consideration of Far Northern conditions.

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Cell-derived vesicles for drug therapy and diagnostics: opportunities and challenges. Cognitive component of componential model of reading applied to different orthographies. Grb7 association to the PDGF beta-receptor was dramatically reduced by replacement of tyrosine residues 716 or 775 with phenylalanine residues. Variation in the distribution of stage at diagnosis, initial therapy including surgical technique, and comorbidity are possible explanatory factors.

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Neither low-dose nor high-dose lead directly affected aortic contractile or relaxant responses. In the present study, we investigated whether zinc affects the PGF2alpha-induced IL-6 synthesis in these cells.

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The 27-bp tandem repeat polymorphism in intron 4 of the endothelial nitric oxide synthase gene is not associated with coronary artery disease in a hospital-based Taiwanese population. ICERs of oncological drugs used in different stages are more unfavourable in the late stage than in the early stage.

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Protocol for the examination of specimens from patients with carcinomas of the skin, excluding eyelid, vulva, and penis: a basis for checklists. Besides using antibodies as conformational probes, the biosensor can also be used to measure directly the binding of a recombinant product to its natural biological ligand.

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The biological half-lives along with the percent elimination of lead by two different decay modes in testis, epididymis, prostate, and seminal vesicles are being reported together with that in liver, kidney, blood, and whole body. A survey was conducted to describe the extent to which BSN and ADN nursing programs in the United States admit and graduate special needs and chronically ill students, and to identify the accommodations which have been successful in providing nursing education to these students. Poly(ADP-ribose) polymerase (PARP) inhibitors have been explored as therapeutic agents for the treatment of hereditary breast and ovarian cancers harboring mutations in BRCA1 or BRCA2. The carboxypeptidase and endopeptidase activities of cathepsins X and B, as well as their inhibition by E-64 derivatives, have been investigated in detail and compared.

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Studies on toxic factors produced by rumen microorganisms of sheep. Radiological findings were generalized platyspondy with excessive intervertebral disc space heights and a large head.

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Post-traumatic segmental bone defects of the femur and the tibia above the critical size require special attention because conventional bone grafts result in high rates of nonunion. A prosegment of the yeast alpha-factor controls a heterologous protein (human growth factor) in Saccharomyces cerevisiae culture media It is apparent that the initial concentration of B30-MDP, relative to the mixed-micelle-to-virosome transition, is an important factor for virosome preparation. Agricultural land is its asset and most importantly its means of sustenance as well as survival.

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Included were patients presenting CSF rhinorrhea subsequent to closed head trauma, admitted within 24h. In 12 of the subjects, the percentage change in plasma volume and in total circulating plasma electrolytes was determined.

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Both fit substantially better than the Correlated Liabilities model. Experiences with an improved modification of radial immunodiffusion in the determination of albumin, transferrin and acid alphal-glycoprotien

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Metastatic disease to the liver is an important disease from the diagnostic, prognostic and therapeutic points of view. An extensive evaluation including specialized labs, ERCP was done.

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True idiopathic aneurysms are the least common and a few reports in children have been published. In both populations, an inverse relationship between glucuronide and sulphate conjugation following a bimodal frequency distribution pattern was found.

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We also monitored tonic releases of lactate dehydrogenase from cultured hippocampi phasically treated with an excitotoxin and from those transiently deprived of oxygen/glucose. To examine the dynamic properties of baroreflex function, we measured beat-to-beat changes in arterial blood pressure (ABP) and heart rate (HR) during acute hypotension induced by thigh cuff deflation in 10 healthy subjects under supine resting conditions and during progressive lower body negative pressure (LBNP). Here, we report that the lysosomal cysteine peptidase cathepsin L (CTSL) is critical for cardiac morphology and function. A 49-year-old obese female was admitted for acute onset pleuritic chest pain. pRB, the retinoblastoma tumor suppressor gene product, regulates the cell cycle at G1/S transition negatively.

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The main treatment algorithms continue to rely on hepatic resection or transplantation with controversies involving patients harboring early stage disease and borderline hepatic function. Important everyday rehabilitation--a responsibility of the leadership Investigation of cutaneous microvascular activity and flare response in patients with fibromyalgia syndrome. The results from this study suggest the view of a complex mechanism of action underlying nifedipine- and nimodipine-mediated behavioral effects.

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Immunohistochemical analysis of minichromosome maintenance proteins (MCM3, MCM4, MCM6, and MCM7), p21, Ki-67, p16, and proliferating cell nuclear antigen (PCNA) was performed in a total of 49 specimens of normal anal mucosa and high- and low-grade anal dysplasia. These five isolates showed non-hemolysis type (gamma-hemolysis), susceptibility to all antibiotics tested except for vancomycin, ability to survive in the simulated gastrointestinal conditions of both acid and bile salt solution, and ability to inhibit growth of E.

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This study was designed to assess the importance of the fecal stream in cholic acid-induced colon tumor promotion. (ii) Development of HPLC sizing column methods to quickly purify BAP-coupled oligosaccharides away from free BAP and other reactants. On the other hand, the two Arg132 mutants, R132A and R132Q, of CRABP-II demonstrated undetectable binding of all-trans-RA.

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To evaluate the benefits and risks associated with various modes of exercise in persons with SCI. Proliferating megakaryocytes displayed a constitutive DNA-binding activity of NF-kappaB p50 homodimers and of NF-kappaB p50-p65 heterodimers. Traditional gene expression analysis techniques verify a high degree of confidence in the microarray data. Effect of ethyl alcohol on the metabolism of lipids and lipoproteins The chloroplast envelope is permeable for maltose but not for maltodextrins.

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Regulation of penicillinase synthesis: evidence for a unified model. Although it is often claimed that statistical techniques are ways of letting the objective data speak for themselves, in both the contrast and correlational modes of statistical inference, all the real work is done by the a priori decisions imported into the analysis--which categories are to be used to create contrasting populations, which categories are to be measured, which categories are to be held constant while others are compared, and which is cause and which is effect? Schizophrenia is associated with a temporal context memory deficit. In addition, human placenta specifically secretes placental growth hormone, the level of which is significantly decreased in the sera of pregnant women bearing a fetus with intrauterine growth retardation.

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Cathepsin K-positive vesicles and granules as lysosomal compartments were present in various stages of fusion with vacuoles as endosomal compartments that contained fragmented cathepsin K-negative fibril-like structures. No evidence of any local recurrence was observed at 4 years of follow-up. The expression of fibroblast growth factor-2 (FGF-2) in the tumor cells was investigated by Western blotting. There are numerous reports of in vitro and in vivo usage of dendritic cells (DC) pulsed with idiotype, the tumor-specific antigen of multiple myeloma (MM), for immunotherapy of MM.

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A 36-year-old man sustained an indolent keratitis following a minor corneal trauma. To determine the diagnostic and prognostic test qualities of the enzyme linked immunosorbent assays (ELISA) for rheumatoid factor isotypes in rheumatoid arthritis (RA), and to compare them with the latex fixation test. Some of the approaches that were used to determine the expression of regulatory states during sea urchin embryogenesis are reviewed.

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In this retrospective study, the records of 351 patients who underwent curative resection for colorectal carcinoma between 1967 and 1991 were reviewed. No clinically significant adverse events, changes in vital signs, or laboratory signs were observed.

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The aim was to establish the earliest time when normal foals have clear, radiolucent lung fields, and to characterize the pattern of this clearance. The purpose of this study was to determine if Taxol induced CYP3A in primary cultures of rat hepatocytes and, if so, whether induction of CYP3A would increase acetaminophen toxicity. Partially covered Gianturco stent for tracheobronchial stricture caused by intraluminal tumor. In vitro reconstitution of mammalian U2 and U5 snRNPs active in splicing: Sm proteins are functionally interchangeable and are essential for the formation of functional U2 and U5 snRNPs.

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A case of orotracheal myiasis in an 80-year-old man in coma for 1 week in the intensive care unit of Baskent University Hospital, Ankara, Turkey, is reported. Action of carminomycin on leukemic cell proliferation and some problems of its use in the combined therapy of leukemias In this review we summarize the available literature regarding the prognostic impact of venous and lymphatic invasion, perineural invasion and tumour budding in colorectal cancer. The data arise from three areas in Albania, the Republic of Macedonia and Romania.

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Serum ECP levels in asthmatic patients: comparison with other follow-up parameters. Is heart failure with preserved systolic function an overlooked enigma? The authors hypothesized that radiosurgery performed using subnecrotic tissue doses would reduce or abolish epilepsy without causing demonstrable behavioral side effects. Individual and group interviews with 27 parents: 18 mothers and 9 fathers from Pakistan, Poland and Vietnam. Chemical cross-linking of somatostatin receptors in rat adrenal cortex.

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Data from the present study indicate that plasma B12 and ferritin levels are low in a group of pregnant adolescents. Medications that improve serotonergic and noradrenergic transmission, such as serotonin-norepinephrine reuptake inhibitors may be effective in treating epilepsy-associated SSRI-resistant depression, as well as concurrent depression and attention-deficit/hyperactivity disorder (ADHD).

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We determined to what extent R-III reflex activity and subjective pain reports were decreased by placebo and we investigated whether these placebo-induced changes in reflex activity and subjective pain reports were naloxone reversible. Our studies indicate that the overall activities of the seven rrn P1 promoters are similar, and the same contributors are responsible for these high activities, but these inputs make different relative contributions and may act through slightly different mechanisms at each promoter. We conclude that back support, but not bell v diaphragm stethoscope head, affects seated BP determinations. Since sex steroids are involved in the regulation of prolactin (PRL) secretion, we have studied the effect of DHEA administration on PRL mRNA levels in both adult male and female rats. Cafestol increases plasma triacylglycerol by increasing the production rate of VLDL(1) apo B, probably via increased assembly of VLDL(1) in the liver.

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The purpose of this study was to evaluate the feasibility, toxicity, and efficacy of the combination of paclitaxel, carboplatin, and long-term continuous infusion 5-fluorouracil (5-FU) in the treatment of advanced squamous carcinomas of various primary sites. In conclusion, young children with poor Eustachian tube function and a large cholesteatoma with erosion of the ossicular chain, are at special risk of recurrence and should be observed for several years after surgery. Immunoblotting using sera collected from rats inoculated orally with oocysts, as well as sera from mice hyperimmunized with sporozoites, revealed that many surface molecules appear to be immunogenic.