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Topimax (Topiramate)

Topimax is a seizure medicine, also called an anticonvulsant. Topimax is used to treat seizures in adults and children who are at least 2 years old. Trokendi XR is for use in adults and children who are at least 6 years old. Extended-release Topimax has a higher minimum age (at least 10 years old) when used as the child's only seizure medicine. Some brands of Topimax are also used to prevent migraine headaches in adults and teenagers who are at least 12 years old. These medicines will only prevent migraine headaches or reduce the number of attacks, but will not treat a headache that has already begun.

Other names for this medication:
Topiramate, Topamax, Epitomax, Letop, Neutop, Piramax, Talopam, Topamac, Topictal, Topigen, Topilex, Topimax, Topina, Topiramato, Topirol, Toplep,

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Patterns of synthesis and distribution of MMPs and their inhibitor, tissue inhibitor of metalloproteinases-1 (TIMP-1), are documented in the craniofacial region at sites of bone formation during both intramembranous (e.g., calvaria, maxilla, and mandible) and endochondral ossification (e.g., cartilaginous cranial base and synchondroses) using indirect immunolocalization. We report the case of a patient with multifocal motor neuropathy. There is a reported relation between hyperhomocysteinemia and lichen planus (LP). The production of functional nanostructured materials starting from cheap natural precursors using environmentally friendly processes is a highly attractive subject in material chemistry today. In addition, the presence of mammalian GnRH in the plasma of the lungfish suggests that this molecular form of GnRH has a hypophysiotropic function reaching target organs (pituitary and gonads) via the general circulation.

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Induction of extraskeletal hematopoietic areas using demineralized tooth matrix Effectiveness of colesevelam hydrochloride in decreasing LDL cholesterol in patients with primary hypercholesterolemia: a 24-week randomized controlled trial. Parents of children with TBI also reported higher levels of psychological symptoms than parents of children with orthopedic injuries. Is there any relationship between quality of life and polysomnographically detected sleep parameters/disorders in stable myasthenia gravis? pylori the cholera toxin B subunit genetically fused to the C-terminal VacA domain.

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We report a theoretical calculation of the elasticity of the peptidoglycan network, the only stress-bearing part of rod-shaped Gram-negative eubacteria. Desipramine suppressed the wheal for 2 days and flare for 1 day. The patterns of protein phosphorylation during development were also not significantly altered by the inhibitors, suggesting that the targets of the inhibitors are minor or unstable phosphoproteins but play key roles in fruiting-body formation in M. Temporal data, kinematic parameters and gait deviation index as a measure of overall gait pathology were assessed. Antibacterial effect of certain associations of streptomycin with other chemotherapeutic agents in experimental tuberculosis in guinea pig

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We show that elevated insoluble tau levels are associated with increased ROCK1 and ROCK2 in PSP and CBD brains, whereas experiments in cellular and animal models identify pharmacologic inhibition of ROCKs as a mechanism-based approach to reduce tau levels. The group treated with pindolol-clopamide had a significant increase in mean body weight and a substantial decrease in serum potassium concentrations. Echographic characteristics of calcifying fibrous pseudotumor of the epididymis Penile HPV infection and disease are very common in sexually active men, and may be manifest in many forms. Once all of the information is available, a complete summary of the findings can be provided to the client.

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A comparison of the tympanic and axillary temperatures of the preterm and term infant. She was in excellent health and had only had rubeola at 3 years of age.

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A novel radio frequency (RF) field intensity mapping or imaging method using a composite NMR spin-echo sequence is proposed. High resolution, two-dimensional electrophoretic profiles of the labelled proteins indicated that the majority of proteins synthesized by adults were also present in the larval stages. Based on these results, further development of the combination of mapatumumab and sorafenib in HCC is not planned. Finally, the PEMT2 gene was localized to mouse chromosome 11 by interspecific backcrossing. In contrast, when EBP50 was cotransfected with ClC-3B, strong immunoreactivity for ClC-3B appeared at the leading edges of membrane ruffles.

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Gonadal steroid hormones appear to influence these changes and retard uterine involution. Studies are needed to clarify the role of breathing pattern in individual differences in resting pCO2 and the effects of breathing interventions on salt sensitivity and sodium sensitive forms of hypertension. Creatine monohydrate supplementation enhances high-intensity exercise performance in males and females.

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Correlation of the eosinophil count with the clinical course during cortisone and ACTH therapy. In this work, we demonstrate that removal of this factor by passage of L cell cytosol through the metal-chelating resin Chelex-100 makes the glucocorticoid receptor unstable, thus markedly facilitating both its dissociation from hsp90 and its transformation to the DNA-binding state. Both the tachycardia return cycle and the V-His interval demonstrated an increasing reset response, while the His-V interval demonstrated a flat reset response. One of these matrices is shown to be equal to the reference vector structure.

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In each case, the temporal response to the initiation of therapy was striking. In this case, the sternum and ribs were removed with subsequent myocutaneous flap coverage for the wound defect. Additionally, the authors discuss the detrimental effect the hallucal interphalangeal sesamoid has on the biomechanical functions of the first metatarsophalangeal and hallucal interphalangeal joints.

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LGIO is defined as a Broders classification grade I osteosarcoma. However, the two psychrotolerant strains with minimal growth temperature of 4 degrees C and 6 degrees C did not contain hbl, as judged from our PCR results. Unexpected findings in trauma patients dying in the intensive care unit: results of 153 consecutive autopsies.

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Results from two laboratories are collated, showing that the method can identify significant contact allergens, particularly those which would be registered formally as such according to European legislation. Computed tomography-guided percutaneous microwave ablation of early stage non-small cell lung cancer in a pneumonectomy patient.

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Synthesis and NMR assignment of two repeating units (decasaccharide) of the type III group B Streptococcus capsular polysaccharide and its 13C-labeled and N-propionyl substituted sialic acid analogues. We sought to further define the usefulness, yield, and sensitivity of endoscopic tissue biopsy in this patient population. The G1 cyclin gene CcnD3, which encodes cyclin D3, is inhibited by dexamethasone in P1798 murine T lymphoma cells. Voltage-dependent anion channels (VDACs), also known as mitochondrial porins, are small channel proteins involved in the translocation of metabolites across the mitochondrial outer membrane.

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Pediatric intraabdominal injuries (IAI) from blunt abdominal trauma (BAT) rarely require emergent intervention. Proprotein convertase 7 (PC7) is a member of the subtilisin-like proprotein convertase family, which is involved in the endoproteolysis of a variety of precursor proteins.

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HLA-DR and DQ DNA polymorphisms in subjects of Asian Indian and white Caucasian origin. These results suggest that downregulation of WT1 expression is necessary for normal differentiation of F9 cells into parietal endoderm cells. Effect of chemical composition of sunflower seed meal on its true metabolizable energy and amino acid digestibility. Evaluation of each phase of the radiographic study showed almost uniform good-to-excellent opacification, with no significant differences among the three agents.

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However, this regimen decreased the incidence of MVO and was associated with transient favorable effects on LV volume and function. Sera and lung tissues were collected and analyzed by quantitative enzyme-linked immunosorbent assay (ELISA) for total protein, superoxide dismutase (SOD), malondialdehyde (MDA), tumor necrosis factor-alpha (TNF-alpha), and interleukin-10 (IL-10) levels. Impact of alarm caused by ozone ambient air pollution in a hospital emergency service The modulation of myogenic function and cerebral blood flow (CBF) by nitric oxide (NO) synthases (NOS) was assessed in the middle cerebral arteries (MCAs) of Kyoto Wistar stroke prone hypertensive rats (SHRsp) in relation to haemorrhagic stroke development. DPE-5986-A-1009-00 with the International Centre for Diarrhoeal Disease Research, Bangladesh (ICDDR,B).

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coli tyrR as a repressor of the aroF-tyrA operon (but not as an activator of mtr) in the heterologous E. This study demonstrates the feasibility of a retrofacial approach to the ST as an aid in eradication of otherwise hidden disease. Natural killer cell-mediated cytokine response among HIV-positive south Indians with pulmonary tuberculosis. Effects of agars on determination of potency of polymyxin B sulfate by the agar plate diffusion method. Development of an ulcer in the side-to-side anastomosis of a jejunal pouch after proximal gastrectomy reconstructed by jejunal interposition: report of a case.

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The primary PCR search in mouse organs revealed the presence of known strains of murine cytomegalovirus (Murid herpesvirus 1) and of Mus musculus rhadinovirus 1 only. The kinetics of sorption of the tested metals was fast, reaching equilibrium within 20-40 min. Five cross sections in the anteroposterior dimension and four cross sections in the transverse dimension were computed which generated 18 2D variables. Stereoselective Synthesis of Isochromanones by an Asymmetric Ortho-Lithiation Strategy: Synthetic Access to the Isochromanone Core of the Ajudazols. Thoracic scoliosis: exothoracic and endothoracic deformations and the spinal penetration index

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Other organic acids, such as malic, tartaric, and succinic acids, were detected in low concentrations (less than 0.5g/L). They were all able to induce inflammatory reaction which was prevented by anti-T-cell (TH) mAb, silica, indomethacin and dexamethasone. Autoantibodies to insulin as serum markers for autoimmune insulitis. Factors affecting differences in apparent size between opposite halves of a visual meridian.

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Genotypic detection methods could potentially identify patients at risk for recurrent progressive disease. The aim of this study was to examine the effect of intestinal bacteria on the local immunoglobulin (Ig) response. We present a novel finding of severe hypertension in a fatal case of Clostridial bacteraemia with massive haemolysis. Using gel retardation assays, we observed a large reduction in the formation of RXR-RAR heterodimers in the HL-60/RA cell line as compared to the parental cell line.

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The hallmark of muscle adaptation to hypoxia in all these cases is a decrease in muscle oxidative capacity concomitant with a decrease in aerobic work capacity. The use of steroids to hasten recovery remains controversial but is routine in most cases.

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The introduction of cysticidal drugs have changed the prognosis of most patients with neurocysticercosis. Correspondence Re: Healy JC, Darcy TP, Sims KL: The role of clinical pathology in academic pathology departments. The use of an SBDNE skin care regimen was important in bringing about a significant reduction in the number of patients with PrUs and respective treatment costs in a medical unit experiencing high incidence rates of PrUs. The population of drugs-addict pregnant women may be characterised as a high risk group from the view of prenatal care. Ten families, including our own, clearly demonstrate autosomal dominant inheritance with female preponderance and great inter- and intrafamilial variability.

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A study on the correlation of blood and vitreous humour alcohol levels in the late absorption and elimination phases. We showed that by the 60th day of hypokinesia and in conditions of active readaptation the disordered cerebral blood flow starts to stabilize and tendency to normalization of some parameters of the cerebral blood flow and microcirculatory channels become clearly seen. Caulobacter, therefore, possesses a simple developmental program and is used as an model system to determine basic mechanisms of cellular morphogenesis.

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This reaction exhibits classical Michaelis-Menten kinetics with a Km of 160 microM and a kcat of 7.7 s-1. Areas covered: The aim of the current review is to summarize, giving a critical overview, of the investigational GnRH agonists, and shortly discuss the difference between the GnRH agonists, antagonists, Kisspeptin, and Neurokinin B analogs. Our methods allow making polypeptide arrays using amplified linear DNA fragments. No cross-linking of actin monomers to form large aggregates appeared to be related to the observed paraquat-induced increase of the filamentous actin pool. Consistent with previous observations, uptake increased and viability decreased with increasing pulse length, total exposure time and pressure.

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These new findings lead to uncovering the basis for the etiological role of cigarette smoking in the disease. Their development requires technical know-how, computing expertise, clinical input, and collaboration-a true meeting of the minds to permit the conversion of wearables from neat gadgets into practical and proficient tools that will propel health care to new heights. Problems detected: difficulty of telephone contact, uncomfortable and lengthy wait, health staff smoking, scant interest from the doctor, no greeting on entry, interruptions during the visit, insufficient information. She had multiple liver metastases and received systemic chemotherapy (UFT-E plus CPT-11) for 6 months. Changes in mediobasal hypothalamic dopamine and GABA release: a possible mechanism underlying taurine-induced prolactin secretion.

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The similarity of average meal size in the two FR conditions suggested that increased meal size did not drive the longer IMIs of desynchrony, although variability of caloric intake from meal to meal within conditions correlated with postmeal and premeal intervals. The authors evaluated the effect of cigarette smoking on the bioavailability of metronidazole in plasma and saliva. Results were examined to ascertain whether there were asymmetries in the distribution of cerebral blood flow through structures, using parametric statistical maps. In particular, there has been a growing body of research on traumatic brain injury (TBI) in children and adolescents.

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Five patients with malignant tumors died from recurrence despite radiotherapy. The collaborative randomised aminoinfusion for meconium project (CRAMP): 1. For more than three decades, conventional coronary artery bypass grafting (full sternotomy, cardiopulmonary bypass, and cardioplegic arrest) has been the treatment of choice for patients with multi-vessel coronary artery disease. The anatomical-physiological facts about the effects of pregnancy and delivery on the urinary tract are presented.

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Age-related changes in the initiation of gait: degradation of central mechanisms for momentum generation. To study associations between established risk factors for pre-eclampsia and different clinical manifestations of the disease. Stereological estimation of particle shape and orientation from volume tensors.

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Analysis of population pharmacokinetics with NONMEM in clinical patients treated with amikacin by intravenous infusion Efficacy of drug regimen exceeds electrostimulation in treatment of avian muscular dystrophy. (6) Increment of IMP (approximately 0.9 mM/l cells) and ITP (approximately 0.5 mM/l cells) did not alter the deformability of erythrocytes. Cows were either not treated or treated with 4.5 mg/kg oxfendazole, 16.6 mg/kg oxyclozanide or 4.5 mg/kg oxfendazole and 16.6 mg/kg oxyclozanide in March, May and August.

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In vitro measurements of inertial cavitation thresholds in human blood. During these infusion regimes, we plan a number of neurobehavioural tests and imaging of the brain to assess neural processing, emotional reactivity and perception, mood and self-perceived well-being. Immunohistochemical localization of taurine in the rat ovary, oviduct, and uterus. To obtain the information, an extensive and up-to-date bibliographic review was done about this topic.

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Biologic variability of cardiac troponin I in healthy dogs and dogs with different stages of myxomatous mitral valve disease using standard and high-sensitivity immunoassays. Bibliographical index of works on rheumatology and osteoarticular diseases The implication of these findings for the survival of rhizobial inoculants, and the ecology of phages and their host bacteria, are discussed.

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Pyrogens fail to produce fever in the leopard tortoise Geochelone pardalis. Omega-3 fatty acid supplementation in noninsulin-dependent diabetes. alpha-Adrenergic blockade reduced both the rise in blood pressure and the magnitude of hypopnea induced by LS. An effective compound which can kill tumors via apoptotic pathway appears to be a relevant strategy to suppress various human tumors.

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Medical information system, health records, and knowledge banks. Our findings suggest that depression-related alterations of inflammatory markers may be more complex than previously assumed, and that at least some of the chemokines may be down-regulated.

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Gap junction formation between cultured embryonic lens cells is inhibited by antibody to N-cadherin. A case of arsenic intoxication associated with macrocytosis and neuropathy, without anemia, is presented. Size has been considered to be the single best predictor of malignancy in adrenal neoplasms that have been identified incidentally.

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Use of formal and informal mental health resources by cancer survivors: differences between rural and nonrural survivors and a preliminary test of the theory of planned behavior. Differences between treated and untreated hypertensive subjects in the extent of periventricular hyperintensities observed on brain MRI. Numbers of deaths from influenza combined with mid-range estimates of numbers of cases of influenza to calculate age specific case fatality rates. The prevalence of other psychiatric disorders was lower than in St. Reduction in the mechanonociceptive response by intrathecal administration of glycine and related compounds.

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In this study, we evoked panic-like behaviour by dlPAG stimulation and evaluated the effect on neuronal activation in different brain regions. The purpose of this study was to determine whether the incidence of bilateral neck disease tonsillar cancer is rising.

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Recommended general principles of good practice relating to psychological examinations in occupational medicine service Recent models explain how attention may have a stronger facilitatory effect on low contrast than on high contrast stimuli, and how pop-out from orientation contrast may occur. Impaired T(H)17 responses were evident irrespective of the STAT3 mutation status, indicating that different genetic forms of HIES share a common functional outcome. Moreover, flight experiments established that proline is an important fuel to power flight metabolism in Onitis species.

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Moreover, we demonstrate that telomere repositioning during meiotic prophase occurs in sectors of the nuclear envelope that are distinct from nuclear pore-dense areas. We aimed to assess the feasibility of both field and en route pre-hospital REBOA in the military exercise setting simulating a modern armed conflict.

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Moreover, both stereoisomers of propranolol were equipotent in suppression of ischemia-induced noradrenaline release, indicating a property of propranolol independent from interaction with beta-adrenoceptors. Parallel and serial processes in the human oculomotor system: bimodal integration and express saccades. We administered a 23-item questionnaire survey to gun buyback participants assessing demographic characteristics, motivation for relinquishing firearms, child firearm accessibility, and mental illness/domestic violence history.

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Administration of cortisol at physiological doses in vivo (1 mg/100 g body weight) to fasted, adrenalectomized rats increased the muscle ratio of glutamine/glutamate and the activity of glutamine synthetase after only 6 hours. The pectoral fin branch ends in an intermediate region of the FL, whereas the hyomandibular, ophthalmic, lower lip, upper lip, and palatine branches terminate in discrete regions of the caudal one-third of the FL. General concepts of adrenocortical function in relation to the response to stress. It has been shown to be a marker of pericytic mimicry, that is, the spreading of tumor cells in a pericyte location along abluminal vascular surfaces. Mechanisms of prostaglandin F2 alpha and histamine-induced contractions in human chorionic vasculature.

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Besides their functions in lipid absorption, bile acids/bile alcohols are regulatory molecules for a number of metabolic processes. Helicobacter pylori seroprevalence increases with age in adult life but spontaneous reversion may occur in childhood and adolescence. Unilateral phrenic nerve paralysis (PNP) folowed 32 (1.7 percent) of 1,891 consecutive cardiac surgical procedures during an 8 year peroid. Simple prednisolone 5 mg indications for colonoscopy serologic tests that unambiguously distinguish among infections by these retroviruses are essential.

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Patients were assessed at 1 month and at subsequent 3-month intervals following the procedure using a questionnaire, AUA symptom score, and uroflowometry. By blocking glutamate receptors in vivo, we show that thalamic responses do not appear to rely on excitatory drive, and we show in a theoretical model that cost of adcirca at costco they could be mediated by postinhibitory rebound properties. Placement of tri-weekly training sessions: importance regarding enhancement of aerobic capacity.

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Retrospective analysis of 12 children with anovestibular fistula and normal anal opening were hemeran gel tim hortons treated between the years 2000 and 2007. Since non-histone, 3H-tryptophan-labelled proteins were not incorporated in the same way, these 3H-arginine-labelled proteins accumulating in pronuclear chromatin during the earliest phase of pronucleus formation are probably histones. Molecular approaches for the diagnosis of 21-hydroxylase deficiency and congenital adrenal hyperplasia. Health care provision in prisons is an area of increasing international concern.

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In this study, we integrated the gene expression data of sepsis to reveal more precise genome-wide expression signature to shed light on the pathological mechanism of sepsis. Modulation of human neutrophil chemotaxis by the endothelin-B receptor agonist sarafotoxin S6c. The risk of advanced histology in small-sized colonic polyps: are non-invasive colonic imaging modalities good enough? Mathematical PKPD and safety model of bispecific TfR/BACE1 antibodies for the optimization oxcarbazepine medication for pain of antibody uptake in brain.

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multiflflora) on endothelin level, total and differential white blood cells (WBC) count of sensitized guinea pigs. Patients were followed to determine length of open drainage, time to removal, related complications, and those who may have benefited. In such situations use of thrombolytic agents produces an improvement in haemodynamics compared to anticoagulants alone, although studies to date have been too small to address the issue resistenz gegen acyclovir medication of mortality benefit. Our analyses failed to reveal any enhanced CST regeneration after experimental spinal cord injury in either line.