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Topictal (Topiramate)

Topictal can be in combination with other drugs to treat partial-onset seizures, primary generalized tonic-clonic seizures, and seizures associated with Lennox-Gastaut syndrome (a severe form of childhood epilepsy). Topictal has both its approved and off-label uses. In the United States, the drug is officially approved by the U.S. Food and Drug Administration (FDA)

Other names for this medication:
Topiramate, Topamax, Epitomax, Letop, Neutop, Piramax, Talopam, Topamac, Topictal, Topigen, Topilex, Topimax, Topina, Topiramato, Topirol, Toplep,

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Measurement of root surface area of permanent teeth in a Chinese population. Genetic diagnosis of dysplasminogenemia: detection of an Ala601-Thr mutation in 118 out of 125 families and identification of a new Asp676-Asn mutation. In vitro results have been confounded by pro-oxidant effects of ascorbic acid and an overlapping role of glutathione. Another option is reduced levels of Th1 cells in IL-6(-/-) mice.

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This article reports the successful use of carbamide peroxide at-home bleaching in a teenager with dentinogenesis imperfecta. No stimulation of immunogenesis with the type C specific antigen was found within the period of investigation.

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Having small structural differences, the selected systems have commonalities in the excited state intramolecular proton transfer (ESIPT) process. Whether patient preference for noninvasive collection methods affects acceptance of HIV screening in clinical practice, however, is unknown. We also recommend formation of an interdisciplinary brain trauma working group in order to control whether guidelines and standardized therapeutic modalities are being followed.

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Navy personnel does not seem to be adversely affected by submarine duty. In this segment of the genome, 1 cM corresponds to a little over 200 kb of physical distance. Eleven of them were started on erlotinib and 23 were started on gefitinib. The mass of silver fox fetuses of both sexes, their gonads, and adrenals, and the levels of testosterone in blood serum and in gonads and adrenals were determined from day 31 of gestation and every five days thereafter until its termination. Intact recognition, but attenuated adaptation, for biological motion in youth with autism spectrum disorder.

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No findings of enteroviruses in Swedish patients with chronic fatigue syndrome. The mechanisms shaping the single-cell transcriptional landscape. Several cell-associated cytokines, such as interleukin-1 (IL-1) and tumor necrosis factor, exist on the cell surface and are biologically active. The mammalian Cos2 homolog Kif7 plays an essential role in modulating Hh signal transduction during development.

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A direct correlation existed between percentage change in BEOT and base deficit, and an indirect correlation was seen with arterial oxygen tension. The physician has to accept a new role as a teacher and tutor, and as such a caring but still professional friend. To determine whether a group of 3 genetic differences in the nonstructural protein (NS1) or 1 genetic difference in the structural protein (VP2) of Aleutian disease parvovirus (ADV) is responsible for an increase in the in vivo replication and pathogenicity of G/U-8, a chimera of ADV-G (nonpathogenic) and ADV-Utah (pathogenic), compared with G/U-10. The gag coding region of the Drosophila telomeric retrotransposon, HeT-A, has an internal frame shift and a length polymorphic region.

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The existence of a subpraventricular rhythm, probably sinusal, and also unapparent in the standard ECG, was observed by using the same method after electrical defibrillation. Our study aimed at discovering the promoting factor of nerve invasion within the tumoral ECM. When rice straw and corn steep powder were used as carbon and nitrogen sources, respectively, the maximal EG activity of 5.0 U mg protein(-1), one of the highest levels among EG-producing microorganisms, was observed. An explicit statement of a statistic which is a nonparametric analogue to one-way MANOVA is presented.

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Homosildenafil was added as a new inspection item and other foods have since been discovered to contain it. Early trypsin is a female-specific protease present in the Aedes aegypti midgut during the first hours after ingestion of a blood meal. This paper argues that there is a real need for the NHS to look at new ways of allowing nurses to study and makes the case for ward-based learning. Based on morphometric studies of mesangial expansion, diabetic nephropathy was determined to be moderate or severe. To test the hypothesis that the alpha-neurotoxin binding site is conserved in Elapidae snakes and to identify the mechanism of resistance against conspecific alpha-neurotoxins, we cloned the ligand binding domain of the Egyptian cobra (Naja haje) nAChR alpha subunit.

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Zebrafish pigmentation mutations and the processes of neural crest development. In several species including monkey, cat and hamster, the paired colliculi are connected by a commissure. CD66b overexpression and homotypic aggregation of human peripheral blood neutrophils after activation by a gram-positive stimulus. In Experiment 1, a high methionine intake level of 512 was compared to 326 mg per hen-day (HD).

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The study was designed to investigate the clinical presentation and laboratory findings of anterior rectal mucosal prolapse (ARMP) and to assess the results of two therapeutic modalities. Declining federal support for human clinical research in general, and autopsy in particular, party reflects the popular view that laboratory experimentation-especially that performed on nonhuman animals-can reliably model human conditions.

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A case of persistent fetal bradycardia first detected at 32 weeks of gestational age is described. Radioisotope scanning in the initial staging of bronchogenic carcinoma. Environmental enhancement of growth factor-mediated oligodendrocyte precursor proliferation. Leigh-like neuroimaging features associated with new biallelic mutations in OPA1. The predominantly older patients mostly wish outpatient treatment.

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The method was tested on several mathematical phantoms as well as on human head data. Arrays of octameric peptide libraries on cellulose paper were screened by using (32)P-autophosphorylated cGMP-dependent protein kinase Ialpha (cGPK) to identify peptide sequences with high binding affinity for cGPK. The composite material offers benefits in ease and speed of construction, has minimal warping and distortion, and has proven patient acceptance. After removal of the VAD, heparin bioactivity was measured by Factor Xa assay. Evidence that the RNAseH activity of the duck hepatitis B virus is unable to act on exogenous substrates.

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The phospholipid hydroperoxide glutathione peroxidase activity was impaired in lung, liver, and spleen of the transgenic animals. Hence, associated tooth injuries are difficult or impossible to treat during immobilization, so that some treatment is necessary beforehand (for example, coverage of exposed dental areas, temporary filling of crown fractures, repositioning of luxated teeth, and endodontic treatment if the pulpal vascular supply is lost in the accident). Dopamine is recognized as the transmitter of one such neural pathway, being involved in at least three major aspects of motivation: modulation of motivational state, acquisition (incentive learning) and expression of incentive properties by motivational stimuli.

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Unilateral acute posterior multifocal placoid pigment epitheliopathy. We also established that the mesodermal source of Ihh is important to maintain specification and also to support the migratory process. Experience of surgical resection of Bismuth-Corlette type I and II hilar cholangiocarcinoma Evidence from controlled trials of laser therapy is presented which suggests that laser therapy can reduce the incidence of rebleeding in such patients with visible vessel. 3C-6 was the predominant subtype in northern China, and the variations between the strains sequenced in our study and those from southern China and Japan were similar, but differences were also identified.

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With highly sensitive CRP assays, serum CRP can add considerably to standard coronary heart disease risk factors and in the prediction of subsequent major CV risk. Colorectal cancer outcomes and treatment patterns in patients too young for average-risk screening.

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Estimation of the EEG power spectrum using MRI T(2) relaxation time in traumatic brain injury. Preferred Reporting Items for Systematic Reviews and Meta-analyses guidelines were followed throughout.

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The effect on peritoneal dialysis pathogens of changing topical antibiotic prophylaxis. When tested for inter-rater reliability, the weighed kappa value was 0.86. The microstructure is characterized by an array of physical methods including image analysis, electron spin resonance and bulk rheology, and it is shown that bacterial survival depends on the formation of microscopic. Metabolic mapping of the forelimb motor system in the rat: local cerebral glucose utilization following execution of forelimb movements mainly involving proximal musculature. The pathophysiologic progression and outcome of different forms of cerebral edema associated with traumatic brain injury have yet to be fully elucidated.

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In control mice, barrels were first seen at postnatal day (PN) 4, whereas in congenital hypothyroid mice they appeared at PN7. The efficacy of percutaneous techniques diminishes significantly when used to treat grafts that have progressed to occlusion.

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Bradycardia often (but not always) accompanied pressor responses, but this was abolished by vagotomy, although not by cutting the sinus and aortic nerves. A 72-year-old woman with a history of early breast cancer suffered a fracture of the eighth thoracic vertebra resulting in paraplegia. Cyclosporine was stable and completely available from the oral dosage form when stored in plastic syringes for up to 28 days. Ovarian volume in postmenopausal breast cancer patients treated with tamoxifen. The biliary excretion of triiodothyronine and thyroxin and their conjugation with glucuronic acid in the liver of thyroidectomized rats

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Determination of the bactericidal effects of antibiotics and of combinations by the Chabert method Membrane type matrix metalloproteinase 1 activates pro-gelatinase A without furin cleavage of the N-terminal domain.

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D1Pas1 was expressed in germ cells, and its expression was developmentally regulated because it was detected specifically in the meiotic and postmeiotic haploid stages of spermatogenesis. Long-term survival improved over time after intact AAA repair despite a change in case mix toward older patients with more comorbidities.

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Enhanced translocation of bacteria across metabolically stressed epithelia is reduced by butyrate. We recently reported a modification of an existing serum HPLC procedure which allows us to analyze whole blood. The genetically epilepsy-prone rat (GEPR) is a valuable model for investigating mechanisms involved in epilepsy because of the controllable nature of the convulsions and their genetic origin. Soluble factors from the olfactory bulb attract olfactory Schwann cells.

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Augmenting Data With Published Results in Bayesian Linear Regression. Most patients with neurofibromatosis type 2 (NF2) lose hearing either spontaneously or after removal of their neurofibromas.

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Dynamics of changes of the reduced glutathione contents, activity of glutathione transferase, glutathione reductase and gamma-glutamyl transpeptidase in rat organs at a single injection of embiquine in a dose of 1/2 LD50 has been studied. AVX-470 is an oral, polyclonal bovine-derived anti-tumour necrosis factor (TNF) antibody in development for treatment of inflammatory bowel disease (IBD). Fetal breathing movements in pregnancies complicated by premature membrane rupture in the second trimester. These studies demonstrate that G beta gamma dimers interact directly with the Kir3.4 channel subunit, and suggest interesting details in the interaction with the major cytosolic carboxyl terminal domain.

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To determine if horses before undergoing anesthesia for surgical correction of colic would have lower plasma arginine vasopressin (AVP) concentrations than healthy horses undergoing anesthesia for arthroscopic surgery, and would not increase their plasma AVP concentrations in response to anesthesia and surgery. Although antifungal azoles show promise, direct screening of compounds against M.

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The behaviour of farmers is modelled assuming perfect information (farmers are fully informed about prevalence, costs of disease and costs of vaccination). Alagille syndrome is a rare inherited condition, which typically manifests during the first year of life as an episode of prolonged cholestasis.

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Further, to assess the impact of this practice on patient safety, staff perceptions of the nursery environments, and to document costs of renovation. Relationship and prognostic value of microvascular obstruction and infarct size in ST-elevation myocardial infarction as visualized by magnetic resonance imaging. Antagonism by exifone, a new cognitive enhancing agent, of the amnesias induced by four benzodiazepines in mice. The two polyclonal antibodies (9433 and 9434) recognized the 384-kDa BRCA2 protein respectively in MCF7 and in CCL 221 cells, but both BRCA2 polyclonal antibodies also cross-reacted with smaller proteins. Second, decorticates do not modify their defensive tactics in response to the social identity of their partners.

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Furthermore, many patients even develop intolerability to statins and resistance. Rats were segregated in four groups: 1) basic high-fat diet, 2) ethanol and a high fat diet, 3) carbonyl iron and a high-fat diet, and 4) ethanol and carbonyl iron combined with a high-fat diet.

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Are uranium-contaminated soil and irrigation water a risk for human vegetables consumers? Based on phylogenetic RepC analyses we identified nine compatibility groups that are expected to stably coexist within the same cell.

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Each subject underwent a self-test for intermediate and high-risk HPV (by HC-II assay), fluorescence spectroscopy, a liquid-based Pap (read manually and by computer and used as a direct test for HPV), a visual inspection (VIA) diagnosis, and colposcopy with multiple cervical biopsies. These results showed that, in rats with portal hypertension, long-term combined administration of octreotide and isosorbide dinitrate improved the hyperdynamic circulation together with a more profound reduction of portal pressure than rats receiving octreotide alone. Elucidating how appropriate neurite patterns are generated in neurons of the olfactory system is crucial for comprehending the construction of the olfactory map. Developmental study of N-methyl-D-aspartate-induced firing activity and whole-cell currents in nucleus tractus solitarii neurons.

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The possible mechanisms of epileptogenesis in the context of focal malformations are complex and poorly understood at present. Functional MRI can be accurately performed in patients with focal brain lesions using a dedicated approach. The results showed that interpreters often felt overwhelmed by the emotional impact of interpreting in mental health services, particularly at the beginning of their careers.

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In this article we discuss recent findings about the role of cytokines in leprosy, tuberculosis and Mycobacterium avium infection, using in vitro and in vivo human and murine data. Several researchers studied the prevalence of soy sensitization in allergic disease. In the first group, a normal immune response was observed, whereas in the second group this response was frankly depressed. Western blot analysis confirmed proteins for MT1-MMP and MT2-MMP in RNK-16 cells.

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The classic hamster cheek pouch model of squamous cell neoplasia requires triweekly application of 9,10-dimethyl-1,2-benzanthracene (DMBA) on tissues for 20 weeks. The GGO areas approximately corresponded to the outer two layers in macroscopic images that were exudative and congestive on microscopic images. Safety, effectiveness and economic evaluation of intra-operative radiation therapy: a systematic review.

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Respiratory stimulation by intravenous injections of lobeline following laryngectomy Each young camel was weighed and abruptly separated from its mother after 30 days of nursing (or at 1 month of age). Diagnostic examination for breast carcinoma was performed at the major hospitals of Norway, and included physical examination by expert surgeon, mammography and/or ultrasonography, and fine needle aspiration cytology when appropriate. Further investigations should focus on the opportunity to target prophylactic antiarrhythmic treatments to patients with large left atrial volumes.

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Age effects on lingual pressure generation as a risk factor for dysphagia. To formulate a patient-rated assessment tool that facilitates the measurement of pain and polysymptom distress directly related to all classes of wounds. A significant weight increase novidat 500 mg tylenol was also evident in the treated animals in comparison with the control group. We concluded that these microstructural features may be related to photosensitivity in patients with JME.

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PKB/Akt and serum and glucocorticoid-regulated kinase (SGK) family kinases are important downstream targets of phosphatidylinositol 3 (PI-3) kinase and have been shown to mediate a variety of cellular processes, including cell growth and survival. When the present results are evaluated also in the light of the vast literature on LDI-MS of carbonaceous materials, the formation of fullerene artifacts seems particularly common for LDI-MS analysis of asphaltenes and other carbonaceous samples with considerably high levels of PAH and varies according to the type of laser lapraz lansoprazole 30 mg obat apa yang used, and the intensity of the laser beam. The clock gene cryptochrome of Bactrocera cucurbitae (Diptera: Tephritidae) in strains with different mating times.

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NF-kB decoy ODNs may allow development of therapeutic and investigative tools for human malignancies. Estimates of the work performed by chiropractors in providing E/M and SMT services gabateva 300 mg etken maddesign were established. This accords with the idea that increased sugar metabolism indirectly induces ldhA.