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The Norwich Patellar Instability Score: Validity, internal consistency and responsiveness for people conservatively-managed following first-time patellar dislocation. Nationwide extensive transport of food materials is discussed as one of possible causes. Mutant spermatocytes cannot efficiently deliver mitochondria and endoplasmic reticulum/Golgi-derived fibrous-body membranous organelle complexes to budding spermatids, and fail to remove actin filaments and microtubules from the spermatids.

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I kappa B-alpha-/- mice have constitutive nuclear factor-kappa B activity, severe skin disease, and neonatal lethality. The nucleotide sequence of the element cloned in pOD3 was determined and analysed.

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The most susceptible gram-negative bacteria were the following: E coli (100 per cent), P. Effect of dexmedetomidine on its clearance: a pharmacokinetic model.

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Tuning curves of the MLR indicate that the MLR is less frequency selective than the ABR. H-2 class I gene analysis in 3-methylcholanthrene-induced murine fibrosarcomas.

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Several interphase methodologies have been applied in this study to investigate whether chemically induced undercondensation of the pericentromeric region of human fibroblast chromosomes promotes structural or numerical aberrations at the cell cycles following treatment. We searched the Cochrane Cystic Fibrosis and Genetic Disorders Group Trials Register comprising references identified from comprehensive electronic database searches and hand searches of relevant journals and abstract books of conference proceedings. Protein synthesis is regulated in response to environmental stimuli by covalent modification, phosphorylating the components of the translational machinery. Immunophenotypic characterization of human basophils and mast cells.

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Treatment for gastroesophageal reflux is feasible with similar effectiveness with open and laparoscopic procedures. Renal cell carcinoma (RCC) is the most common malignancy in the genitourinary tract, and is among the 10 most common cancers in both males and females. Recent attention has been given to a reexamination of results from the early Viking missions to Mars that suggested the presence of one or more strong oxidants in Martian soil. No moderator effects were found, and the number of studies was small. Among 30 outpatients with bipolar disorder and 31 normal comparison subjects (NCs), we administered the UCSD Performance-Based Skills Assessment (UPSA) and 2 subjective measures of functioning.

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Individual corpuscles consisted of a central nerve fiber surrounded by 35 to 60 concentric lamellae (normal controls from other specimens: 13-15 lamellae). Overexpression of manganese superoxide dismutase suppresses tumor formation by modulation of activator protein-1 signaling in a multistage skin carcinogenesis model. The cumulative effects of social class on mental status decline. Correlation between carcinogenicity and polarographic reducibility of some N-substituted derivatives of 4-aminoazobenzene. Use of the newer drug appears to have no advantages over use of the accepted standard treatment.

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This continuum was enhanced during reversion, suggesting that the establishment of a continuum partly reflects limiting amounts of inductive signal exported from the leaf to the meristem. Mutagenesis and modelling of the alpha(1b)-adrenergic receptor highlight the role of the helix 3/helix 6 interface in receptor activation.

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Arthroscopic techniques may also be quite useful in the evaluation and treatment of the same disorders in sheep, goats, and camillids. Compared with the plain morphine group, addition of epinephrine significantly decreased morphine concentrations in the azygos vein only at 5 and 10min after administration. Re: Stent placement at the venous anastomosis of a dialysis graft: be cost-effective and demanding with regard to the result. HeLa and 293 cells were stably transfected with plasmids that carry the AAV2 rep/cap genes under transcriptional control of their endogenous promoters (p5, p19 and p40) either on the pCEP-rep/cap or an integrated (pIM45) plasmid. The allergist as an educator: an evolving relationship between specialty and primary care clinicians.

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In-vitro activity of 3-azinomethyl-rifamycin (SPA-S-565) against Chlamydia trachomatis. Does restricted distribution limit access and coverage of yellow fever vaccine in the United States?

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There was no obvious correlation of loss of a copy of normal chromosome 14 and reexpression of tumorigenicity in any of the other hybrid cell populations. Questionnaires including the Patient Global Impression of Improvement Scale were readministered postoperatively. Direct measurements of the periacetabular deformation under load revealed an increase of the peripheral press-fit with increasing stability of a (oversized) press-fit cup. Anal submucosal injection: methotrexate concentration in rectal tumor tissue and serum after anal compared with parenteral injection.

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Stability-preserving decompression in degenerative versus congenital spinal stenosis: demographic patterns and patient outcomes. Steady-state levels of APN mRNA increased approximately 10-fold during the 6-day culture. Therefore, it is challenging to quantify the uncertainty of a computational result, which, however, is necessary to assess the suitability of a computational model.

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Application to a GWAS meta-analysis of coronary disease with 48 contributing studies uncovered substantial systematic between-study heterogeneity, which could be partly explained by age-of-disease onset, family-history of disease and ancestry. This is the first description of the isolation of a complete cDNA encoding a putative peroxidase from a gymnosperm. Molecular characterization of Diplozoidae populations on 5 species of Cyprinidae: new data on parasite specificity Although a fascination to botanists at the turn of the twentieth century, members of this genus are unremarkable in appearance, never flower, and are of no agronomic value.

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In the endothelial cells lining the central arteries, arterial capillaries and pulp veins, the surface coat of the luminal plasma membrane included heparan sulfate, chondroitin sulfate A and/or C, chondroitin sulfate B and sialic acid residues, whereas the corresponding ultrastructure of the splenic sinuses was devoid of detectable amounts of acidic glycoconjugates. Eleven young men were confined to a metabolic research unit for 90 d to determine the effect of the amount of dietary copper on copper nutriture. The system of the medical honorarium should be entirely open and publicly regulated. Removal of lipids results in an increased tendency of the enzyme for self-association and a decreased stability.

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To assess whether the detection of minimal residual disease by RT-PCR is improved by concomitant analysis of sentinel lymph nodes (SLNs), bone marrow (BM) and peripheral blood (PB) in patients with primary melanoma. In producing hypothermia and sedation, the three compounds were equiactive.3. For preferred direction of FM sweep, similar results were observed for both age groups, namely, approximately half of the units exhibited a direction-selective response. We find that this model is consistent with many experimental studies of PS II.

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The percentage and nature of local recurrence, tumor-free survival and the progression rate (which was not observed during the short follow up period) indicate that TUR is a treatment option that must be taken into account in selected patients with invasive bladder cancer. Hepatocellular carcinoma (HCC) is a highly prevalent and lethal neoplasia, the management of which has significantly improved during the last few years. Residues of Dacthal and its monoacid and diacid hydrolytic ester cleavage metabolites were determined in carrots to which the herbicide was applied on seven plot locations throughout the United States. The electronic connection of single molecules to nanoelectrodes on a surface is a basic, unsolved problem in the emerging field of molecular nanoelectronics. Tumor spread was identified by combined lymphovascular involvement and stromal invasion in five of the 16 cervices, lymphovascular involvement alone in four cervices, stromal invasion alone in two cervices, lymphovascular involvement with stromal invasion and cervical implantation in two cervices and cervical implantation alone in three cervices.

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Mutants of Saccharomyces cerevisiae with defects in acetate metabolism: isolation and characterization of Acn- mutants. However, the molecular mechanism underlying the regulation of the specificity is largely unknown. Articles were coded to determine whether they included one or more studies using qualitative research and, if so, the types of qualitative studies performed, the sample extensiveness of each study, and mention of sample extensiveness limitations in the article.

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Malignant pleural mesotheliomas is in most cases associated with elevated amounts of hyaluronan. Findings concerning the segregation of motion and color information have been at the forefront of the evidence in favor of the parallel processing scheme. Afterwards three different doses (50, 100, 150 mg daily) of the calcium antagonist Ro 40-5967 were administered to three groups of 14 subjects each for 1 week concurrently with digoxin 0.375 mg daily. Marked resistance during retrograde biliary stent placement: another O-ring problem.

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Electroconvulsive shock as a traumatic (fear-producing) experience in the albino rat. We also compared conventional two-dimensional (2D) with three-dimensional (3D) measurements. Here, we review recent work that has shed light on female gametophyte development and function with a particular focus on approaches that have led to the isolation of genes involved in these processes.

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Occurrence and genetic diversity analysis of apple stem pitting virus isolated from apples in China. The Km value of PGF synthase for retinal was about 20 microM, a same order to that for PGH(2).

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Feeding beyond the pylorus is associated with a significant reduction in gastroesophageal regurgitation and a trend toward less microaspiration. Arabidopsis makes use of a two-component signaling system to mediate the response to the plant hormone cytokinin. A posterior fusion was performed and the posterior wound closed. Localization of proline-like immunoreactivity in young rat retinal neurons.

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The effect of time-of-day and Ramadan fasting on anaerobic performances. These projection cell groups, and hence the higher-order visual areas to which they project, likely obtain their functional properties not from biased retinogeniculate inputs but from highly specific circuitry within the cortex. Phosphine coordination to a cobalt diimine-dioxime catalyst increases stability during light-driven H2 production. Ploidy data correlated strongly with conventional morphological parameters.

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Latanoprost administered once daily caused a maintained reduction of intraocular pressure in glaucoma patients treated concomitantly with timolol. Using small-angle neutron scattering, the effect of ibuprofen, a prominent NSAID, on the radius of small unilamellar vesicles of 1,2-dimyristoyl-sn-glycero-3-phosphatidylcholine (DMPC) and their bilayer structure was studied systematically as a function of pH (ranging from 2 to 8) and drug-to-lipid mole ratio (from 0/1 to 0.62/1 mol/mol). CPE inhibited the H(2)O(2)-induced phosphorylation and internalization of connexin 43, which is a regulating protein of GJIC in RLE cells. Thiamine and benfotiamine prevent human pericyte apoptosis, indicating this vitamin as an inexpensive approach to the prevention and/or treatment of diabetic complications. Supervision structures and methods are presented and the theoretical under-pinnings of the supervision model are discussed.

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We also identified marked differences in the quality of care planned after hospital discharge for black and Hispanic patients, compared with white patients. Within those 2-mercaptoethanol levels, both rat and dogfish metallothionein migrate as a protein with a molecular weight several times higher than that expected by amino acid analyses. The potency of CM 57755 was comparable with that of cimetidine as shown by similar doses causing a 5-fold displacement to the right of the dimaprit dose-response curve (4.9 mumol kg-1 h-1 for CM 57755 and 4.7 mumol kg-1 h-1 for cimetidine). Retroplacement of the four horizontal rectus muscles is a safe and effective procedure for the reduction of nystagmus and the improvement of vision, particularly for near vision, producing little or no induced strabismus or limitation of motility.

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All doses of PACAP used (0.1, 1 and 10 micrograms/ rat, i.c.v.) significantly increased median eminence DOPA concentrations at 60 min. The increasing scientific and industrial interest towards metabonomics takes advantage from the high qualitative and quantitative information level of nuclear magnetic resonance (NMR) spectroscopy.

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Abuse of dieting agents is a frequent, but often unrecognized, problem in patients with eating disorders. Second, endogenous NO may modulate sympathetic activity tonically, by a direct or indirect action on sympathoexcitatory neurons within the rostral VLM. The structure of the domain from simian virus 40 (SV40) large T-antigen that binds to the SV40 origin of DNA replication (T-ag-OBD131-260) has been determined by nuclear magnetic resonance spectroscopy. In the work presented here, we explored the role of leptin in the development of spontaneous autoimmunity in the nonobese diabetic (NOD) mouse, an animal model for the study of human insulin-dependent diabetes mellitus (type 1 diabetes).

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In an AFDE, the highest derivative of the state-space coordinate appears with delayed argument only. Unable to confidently classify these patients, we reviewed their clinical progress for unifying features. Vascular endothelial growth factor (VEGF) and beta-catenin both act broadly in embryogenesis and adulthood, including in the skeletal and vascular systems. 2nd International Heinz Nixdorf Symposium on Applied Immunology: Exercise and Sports of the German Federation of Sports Medicine. The median latency period (time between initial asbestos exposure and diagnosis of malignant mesothelioma) was 19 years.

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The movement of bacteria through groundwater is a poorly understood process. The study enrolled 170 health facilities from nineteen randomly selected districts in Punjab and NWFP.

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No increase in intraocular pressure was recorded during the inflammation. Characterization of platelet-reactive antibodies in children with varicella-associated acute immune thrombocytopenic purpura (ITP). Mitochondrial COI sequences in mites: evidence for variations in base composition. Sustained esophageal contraction: a marker of esophageal chest pain identified by intraluminal ultrasonography.

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After extensive investigations, a diagnosis of erythema elevatum diutinum accompanied by peripheral ulcerative keratitis was made. Rat locus coeruleus-hippocampus double in oculo brain grafts were studied with high-speed electrochemical techniques to characterize stimulus-evoked overflow of norepinephrine.

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Understanding the role of monocytic cells in liver inflammation using parasite infection as a model. Recent developments in therapeutic applications are further examined for clinical utility and as an economical alternative to traditional clinical treatment modalities. In an additional series, subjects were instructed to respond as quickly as possible. Far-red light-insensitive, phytochrome A-deficient mutants of tomato.

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In three of the cases, the electron microscopy identified nuclear and cytoplasmatic viral particles ranging from 40 to 60 nm in size, compatible with HPV. Significant recent advances in the understanding of plant defense mechanisms include the isolation and characterization of resistance genes against bacterial, fungal and viral pathogens, the identification of genes involved in cell death, and the demonstration of the involvement of reactive oxygen species and salicylic acid in the signal-transduction pathways for expression of induced resistance.