Spirolang can be used in combination with other diuretics, primarily furosemide, to produce additional diuresis (generally a mild increase) or to decrease potassium excretion. In addition, as an aldosterone antagonist, Spirolang is considered a neuroendocrine modulator (aldosterone receptor blocker). One human study reported that low-dose Spirolang (subdi -uretic doses) reduced heart failure mortality by approximately 18–40% and this effect was attributable to its neuroendocrine modulatory effects. Spirolang is also used in the management of fluid retention associated with noncardiac disease such as hepatic disease and nephrotic syndrome. Spirolang might be particularly useful as a diuretic in the setting of right heart failure causing ascites.
Other names for this medication:
Spironolactone,
Aldactone,
Aldactazide,
Aldactazine,
Aldazida,
Aldazide,
Aldozone,
Alexan,
Alizar,
Carpiaton,
Espirone,
Espironolactona,
Expal,
Kespirona,
Lanx,
Letonal,
Osiren,
Osyrol,
Practon,
Prilactone,
Spiractin,
Spiresis,
Spirix,
Spiroctan,
Spirolang,
Spirolon,
Spiron,
Spirono,
Spironolacton,
Spironolactona,
Spironolakton,
Spironolattone,
Spirotone,
Verospiron,
Xenalon,
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All of the 19 sera from EIAV-infected horses tested contained antibodies that recognized EIAV RT and directly inhibited the polymerase activity of the enzyme. A wide variety of carcinogens including Ames assay (Salmonella) positive as well as Salmonella-negative carcinogens induce intrachromosomal recombination (DEL lamotrigine dosage form recombination) in strain RS112 of Saccharomyces cerevisiae. Chronic beryllium disease is an occupationally acquired granulomatous lung disease similar to sarcoidosis. The most apparent neurological complications are known to be cerebral injury, spinal cord lesions, peripheral-nerve injuries and motor neuropathies. While there is some evidence that inactivity is associated with increased risk of morbidity and mortality, there appears to be much stronger and consistent evidence for a graded inverse relationship between physical fitness and morbidity and mortality.