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Sendoxan (Cyclophosphamide)
+ BONUS
 
Cyclophosphamide

Sendoxan is used in the treatment of chronic lymphocytic leukaemia, lymphomas, soft tissue and osteogenic sarcoma, and solid tumours. It is given orally or intravenously. Sendoxan is inactive until metabolized by the liver. Before you begin treatment with Sendoxan, you and your doctor should talk about the benefits of this medicine as well as the risks of using it. This medicine is available only with your doctor's prescription.

Other names for this medication:
Cyclophosphamide, Cytoxan, Ciclofosfamida, Cryofaxol, Cycloblastin, Cycloxan, Cycram, Endoxan, Endoxana, Genoxal, Neosar, Procytox, Sendoxan,

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Expression of epidermal growth factor, transforming growth factor-alpha, and their common receptor genes in human umbilical cords. Combined high-performance liquid chromatographic-radioimmunoassay method for the analysis of endorphins, enkephalins and other neurotransmitter peptides. Furthermore, our data showed that FOXA1 is subjected to O-GlcNAcylation, which instabilizes FOXA1 protein and promotes breast cancer cells invasion. In this review, we present what is currently known regarding the role of methylglyoxal in the healing of diabetic gastric ulcers.

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This open-label, multicenter, non-randomized phase 1b study assessed the safety/tolerability, pharmacokinetics, and tumor response of galunisertib plus gemcitabine in Japanese patients with advanced or metastatic pancreatic cancer. There was no difference between males and females in the application of sports metaphors as general metaphors for teams. Intranidal recapillarization can occur later than 3 months after the first embolization with NBCA if total and solid casting of the nidus was not accomplished.

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Two mutant alleles of the human cytochrome P-450db1 gene (P450C2D1) associated with genetically deficient metabolism of debrisoquine and other drugs. This paper discusses both UK-based and global Internet data bandwidth growth, beginning with historical data for the BT network. A 68-year-old man, without any preceding hepatic or abdominal disease, suddenly developed a severe septic illness with consumptive coagulopathy and upper abdominal pain. Utilizing this three piece system, we were able to determine a pathway of the electrons through DsbD.

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Interactions between pesticides and components of pesticide formulations in an in vitro neurotoxicity test. Occupation and lung cancer mortality among women: using occupation to target smoking cessation programs for women.

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Hybrid 3-D rendering of the thorax and surface-based virtual bronchoscopy in surgical and interventional therapy control Although obesity has been, in general, associated with glomerular hyperfiltration, visceral adiposity has been suggested to be associated with reduced glomerular filtration. Nifedipine, diazoxide, or sodium nitroprusside appear to be more rational choices for this problem.

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Restoration of the facial skeleton and associated soft tissues after trauma involves accurate clinical and radiologic assessment to effectively plan a management approach for these injuries. We start with an eye-brain system model inferred from the works of current vision researchers, which consists of a bank of paralles spatial frequency channels and image detectors.

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Dynamic NMR methods, such as differential line broadening and transferred NOE spectroscopy, are normally reserved for the study of small molecule ligand interactions with large protein receptors. The hepatitis C virus (HCV) genome contains the code for a conserved, serine-type protease, called NS3, for the processing of the non-structural protein region of the viral polyproteins. Met-enk 0.1 and 1 mg.kg-1 ip for 6 d enhanced serum IL-6 levels. To this end, BALB/c mice received a dose of 5 ng/50 nl of morphine sulfate, via a stainless steel injection cannula, inserted into either the medial septal area (MS) or the lateral septal nucleus (LS), when they are close to the end of one of the two choice arms of a Y-maze (acquisition period). Calcium-channel blockers inhibit human low-density lipoprotein oxidation by oxygen radicals.

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Cardiac myocyte hypertrophy, the main compensatory response to chronic stress in the heart often progresses to a state of decompensation that can lead to heart failure. Abdominal aortic coarctation, renovascular, hypertension, and neurofibromatosis.

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Should psychiatric patients be granted access to their hospital records? A variety of surgical interventions are available to halt or improve progression of the disease.

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To assess structural social network characteristics and perceived loneliness in fibromyalgia syndrome (FMS) patients and healthy controls. Long-term high-altitude hypoxia increases plasma nitrate levels in pregnant ewes and their fetuses.

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These techniques, used in concert, demonstrated that methanogens of several physiological groups were present in highest numbers in the mid regions of 25 cm deep peat cores. Cyclophilin B (CyPB) is secreted in biological fluids such as blood or milk and binds to a specific receptor present on the human lymphoblastic cell line Jurkat and on human peripheral blood lymphocytes. In comparison with CPK, we detect the clear relation between the cause of death and isozyme patterns in LDH.

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Formate, benzoate, n-hexadecane, and bis(2-ethylhexyl)phthalate caused no priming, and phenol caused only a transient one. MAR displayed curved sections of branched vessels on one image, cut through the axis of vessels to show the vessel diameter objectively, and allowed the viewing direction to be altered arbitrarily. Information on self-care behaviours and use of services was obtained. The present prospectively designed 15-year longitudinal research was conducted to study whether locus of control is linked to diagnosis, to major symptoms, to functioning and recovery, and to personality for schizophrenia patients, depressive patients, and patients with other major disorders.

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The stem stresses were lower for the CF/PEEK prosthesis than for the titanium prosthesis. Multidrug resistant tuberculosis (MDR-TB) belongs to the most serious forms of TB. Super-selective renal arterial embolism can provide definitive therapy in renal trauma, and major surgery may be avoided in most cases. We evaluated the effect of tachycardia-induced CHF on pulmonary ET-1 kinetics. Glomerular cell replication and cell loss through apoptosis in experimental diabetes mellitus.

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The RNA transcript is polyadenylated, suggesting that it can undergo translation within the cytoplasm of an MCMV-infected cell. Although recreational injuries are less frequent than job-related injuries in the study population, they contribute disproportionately to lost duty time. Use of Lycoris radiata agglutinin allowed determination of the molecular interactions with large biomolecules containing mannose oligomers and polymers. A long-term reproducibility test with both types of functionalization showed that the efficiency of the linear polymer coating decreased significantly over time.

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Instruments used were the State-Trait Anxiety Index, the Crown-Crisp Experiential Index, the Hassles Scale, and the Interview Schedule for Social Interaction. We present an infant with HLH and constitutional inversion 9 (p23q31) in cells from bone marrow, lymphocytes and fibroblasts. The selection interview in the assessment of suitability for nurse training. Pregnant patients in their first trimester with IUD in situ who underwent prior unsuccessful ultrasound-guided IUD extraction. These organisms not only have pathogenic potential, they may also be multiply resistant to antibiotics.

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Need for animal experiments using urine in urogenital tuberculosis--the clinical viewpoint Polysaccharides from both strains have 2,3, 4-triamino-2,3,4-trideoxy-alpha-galacturonamide derivatives at their nonreducing ends, a monosaccharide identified for the first time in nature.

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Paper Microzone Plates as Analytical Tools for Studying Enzyme Stability: A Case Study on the Stabilization of Horseradish Peroxidase Using Trehalose and SU-8 Epoxy Novolac Resin. The patient subsequently underwent curative gastrectomy performed with latex-free procedures.

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Treatment with lamotrigine reversed the increase in the immobility time in the deprived rats. The fracture patterns of 16 upper denture wearers suffering maxillary fractures were retrospectively studied. In tail artery, there were no differences in contraction and phosphoinositol metabolism in response to AII in the different ages. Drugs during pregnancy and breast feeding: it now becomes easier to avoid hazardous preparations He was successful because of his steadfast belief that academic anesthesia could and must flourish and his incessant optimism no matter how daunting the many obstacles in his professional life.

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We therefore used this method to study the time courses of several neurochemical parameters which have been shown to indicate ischaemia in animal models (ascorbic acid, glutathione, cysteine, uric acid, glucose, lactate and pH), during such a bypass operation. In patients with heart rates of 65 beats/min or less, the higher temporal resolution of dual-source CT coronary angiography results in improved accuracy and specificity for the diagnosis of significant stenoses on a per-segment level at a similar radiation dose, but provides a comparable diagnostic accuracy on a patient-based level as does 64-section coronary angiography. A single-stranded oligothymine peptide nucleic acid (PNA) was used as a template for the assembly of a chiral oligo(p-phenylenevinylene) diaminotriazine derivative (OPV) in methylcyclohexane (MCH) revealing nanostructures in which the size is controlled by the template. Lack of correlation between p53 protein level and sensitivity of DNA-damaging agents in keratinocytes carrying adenovirus E1a mutants.

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Neural computational prediction of oral drug absorption based on CODES 2D descriptors. The pathophysiology of DHF/dengue shock syndrome (DSS) is related to sequential infection with different serotypes of the virus, variations in virus virulence, interaction of the virus with environmental or host factors and a combination of various risk factors. The PD machinery is composed of cyanobacteria-descended components such as FtsZ and eukaryote-derived proteins such as the dynamin-related protein, DRP5B.

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With this information it should now be possible to ascertain the basis for the apparent predominance of H1 and H2 in non-renal tissues. themolysis due to significant isoantibody infusion and bleeding associated to abnormal platelet function occur more rarely during intensive replacement therapy with clotting factor concentrates. Hypoxia-induced catecholamine release from rat carotid body, in vitro, during maturation and following chronic hypoxia. The major Hex isozymes in humans, Hex A, a heterodimer of alpha and beta subunits (alphabeta), and Hex B, a homodimer of beta subunits (betabeta), have different substrate specificities. The action of Scutellaria baicalensis in B-1F cells was studied in more detail.

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In this review, the authors include research on processing objectives, attention, encoding, storage, retrieval, processing, response, feedback, and learning in small interacting task groups. The quaternary structure of the adenovirus early region 1B 54K protein has been examined under denaturing and nondenaturing conditions. The results from this study suggest that peer leaders appear to be more effective in establishing conservative norms and attitudes related to sexual behaviour than the adults. We studied the mechanism of 15-LOX-1 induction in A549 lung epithelial cells and found that genistein, a potent tyrosine kinase inhibitor, prevented phopsphorylation of STAT6, its binding to the 15-LOX-1 promoter, and the expression of catalytically active enzyme.

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The inhibitory effect of the three agents on collagenase gene expression was partially reversed by exogenous PGE2, which confirms that major histocompatibility complex class II-induced collagenase gene expression is regulated through a PGE2-mediated pathway. Toxicity of clomazone and its formulations to zebrafish embryos (Danio rerio). These units allow a quantitative evaluation of all measurement data (e.g. Hormonal findings revealed increased thyroid function, but the thyroid gland was normal in size and texture. The discussion is thus based on the side-on peroxo cores, omitting the case of complex 8 for which the most favored structure is the trans-peroxo due to para substitution and the steric encumbrance produced by the methylation of the aminic N atoms.

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TD, a quantitative and simple clinical parameter, easily assessed in all patients, offers a reliable tool for evaluation of tumor cell distribution in B-CLL. The LC50 value of the purified inclusions was 4.92 micrograms ml-1 for the moth-fly larvae, while no mortality was shown in the mosquitoes Culex pipiens molestus and Anopheles stephensi, at protein concentrations up to 10 mg ml-1.

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In the remaining patients, resistance decreased, increased or showed complex changes. Structural analyses revealed that it is a unique type of phosphatidylinositol (PtdIns) bearing a branched-chain fatty acid (14-methyloctadecanoic acid). The effect of this antibody on liver colonization by H-59 cells was analyzed.

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Thus, the disruption of Rb-mediated repression may be a contributory factor in leukemogenesis. Here we report an analysis of the subunit composition and substrate specificity of the NSL complex. A model describing the ciliary driven flow and motion of suspended particles in downstream suspension feeders is developed.

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The diagnosis in a child under 16 years should be based on finding a total cholesterol concentration greater than 6.7 mmol/l and a low-density lipoprotein cholesterol concentration above 4.0 mmol/l on at least two measurements taken more than one month apart. Cell wall synthesis in bacteria is spatially organized by cytoskeletal structures. We reasoned that Chlamydia uses the gatCAB-encoded amidotransferase to generate both Asn-tRNA and Gln-tRNA. A blood cyst of the orbit is an unusual cause of proptosis and most likely arises in a pre-existing haemangioma. Severe WML at baseline is an independent predictor of risk for stroke from arteriolosclerosis, while progression of WML during follow up may be associated with subsequent stroke in patients with initially mild WML.

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In vitro activity of the trinem sanfetrinem (GV104326) against gram-positive organisms. healing by first intention in spite of a peripheral amputation level below the knee or at the knee) we developed a score by analyzing 500 patients with 523 amputations retrospectively. By means of immunofluorescence microscopy and transmission electron microscopy, it could be shown that these subpopulations closely recapitulate stages of embryonic rhabdomyogenesis both in vitro and in vivo, but differ in their particular range of maximum differentiation. Bidirectional regulation of mitochondrial gene expression during developmental neuroplasticity of visual cortex.

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The occurrence of multiple carcinomas in one thyroid is frequently observed, although some carcinomas are solitary. The late-phase SITC can provide prognostic factors for the outcome of cervix carcinoma, that is, a large tumor volume with increasing late-phase SITCs is associated with poor outcome. Results of Study 3 suggested that dialectical self-views played an important moderating role that determines whether malleability is associated with negative psychological outcomes. The base of skull, the nasopharynx, and the parapharyngeal space are among the most anatomically complex regions of the body.

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Solution NMR characterization of the thermodynamics of the disulfide bond orientational isomerism and its effect of cluster electronic properties for the hyperthermostable three-iron cluster ferredoxin from the archaeon Pyrococcus furiosus. The effects of the fat component of propofol solution of ketogenesis during propofol anesthesia

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For all patients with CKD, mortality was significantly greater for those with medium- or high-risk compared to low-risk IMRS categories, among each CKD stage. Incidence of human STEC O157 and tHUS, proportion of cases reporting bloody diarrhoea, hospitalisation, tHUS and death. The QRS pattern of pre-excitation was preserved throughout these events. In this study, we investigated the correlation between p53 and bcl-2 in gambogic acid (GA)-induced apoptosis. New experimental evidence suggests that the mechanism of action of antidepressants includes the induction of neurotrophic factor synthesis in selected brain areas.

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Injections of okadaic acid, but not beta-amyloid peptide, induce Alz-50 immunoreactive dystrophic neurites in the cerebral cortex of sheep. All of the coaxial BNC connections were replaced with Triax (TRB) connectors with the exception of the output from the voltage source.

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Loss of heterozygosity and microsatellite instability, which reflect inactivation of tumor-suppressor genes and genomic instability, occur with increased frequency in HIV-associated squamous-cell carcinoma. These experimental data are freely available in online structural databases. The final result of surgical treatment shows that children can significantly benefit from an early developmental period without anticonvulsant medication or intractable seizures with improvements in both IQ and behavioral interactions. Treatment of hip instability (subluxation or dislocation) in patients without quadriceps function was not necessary. Together, these results underscore the importance of considering multiple pathways and articulatory loops during language tasks and provide evidence for a print-to-speech neural network.

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After 2 days of preculture with low levels of hCG, human granulosa luteal cells were placed in suspension culture for 1 h in the presence of isobutylmethylxanthine (100 microM). The authors studied ways of utilization of arginine and of the products of its metabolism (ornithine, agmatine, and urea) in the microoganisms of Citrobacter genus. Protein kinase C differently regulates quisqualate- and 1S,3R-trans aminocyclopentane dicarboxylate-induced phosphoinositide hydrolysis during in vitro development of hippocampal neurons.

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Macronuclear development in Euplotes woodruffi following conjugation. Developmental regulation of connexin 43 expression in fetal mouse testicular cells. Characteristics and Challenges of Open-Water Swimming Performance: A Review.

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However, serum from myopathic lambs did show a reduced opsonic capacity. Inter-laboratory evaluation of the bioluminescent Salmonella reverse mutation assay using 10 model chemicals. The increase of neuronal firing frequency observed in Vim suggests that the pathophysiology of ET may be correlated with excessive activity of cerebellum. Serum osteoprotegerin levels are increased in patients with advanced prostate cancer. Stressors and coping in individuals with chronic kidney disease.

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Nonmammalian vertebrates express at least two forms of GnRH and distinct forms of GnRH receptor (GnRH-R) have coevolved with their ligands. The use of accelerating electric stimulation of the left atrium in patients with a suspected small-focus myocardial infarct These results advocate for new treatment strategies to combat the long-term and extremely costly effect of these wartime injuries.

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IgM antibodies were found in 9/11 sera taken within 3 days after onset of clinical symptoms and in all sera (37/37) taken 4--15 days after onset of the disease. The presence of a 37 kDa 2-5A binding protein in extracts of peripheral blood mononuclear cells may distinguish patients with chronic fatigue syndrome from healthy subjects and those suffering from other diseases.

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Pretreatment of rats with corn oil, aminooxyacetic acid (AOA), buthionine sulfoximine (BSO), or diethyl maleate (DEM) was given intraperitoneally 1 h or 4 h prior to injection of DCP. After injection of normal human myoblasts, regenerating fibers expressed human beta-spectrin, confirming they were derived from fusion of human myoblasts. This new method provides reproducible data and can be used reliably by non-expert examiners. White spot syndrome virus (WSSV) is a devastating pathogen of crustaceans that causes huge losses to global shrimp farming. However, ecologists disagree for two main reasons about the relative roles and influences that density-dependent and density-independent processes have in determining population size.

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This makes Xenopus ACES cells a suitable model system to direct differentiation of stem cells toward retinal fates and encourages further studies on the role of Noggin in the retinal differentiation of mammalian stem cells. Two alternative immunomagnetic beads (IMB) were tested for direct detection of C. For enormous protein breakdown in trophozoite stage, many efficient and ordered proteolysis esita mazumdar hdfc standard life insurance networks have been postulated and exploited. The membrane thickness of wet capsules and the elastic modulus of dry capsules increased following first-order kinetics with an increasing curing time. Inhibition of the elastase-like esterase in human leukocyte granules by human leukocyte cell sap.

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Several attempts have been made to find an appropriate therapeutic concept to significantly lower the rate of PCO. In contrast, enzyme indices dieta perative rth 1000 ml sterile water of tissue maturation did not respond to corticosterone until d9. To identify the change of channel situation between NLOS and LOS, a low complexity identification method based on innovation vectors is proposed. Human methadone self-administration: effects of diazepam pretreatment. Cardiovascular magnetic resonance imaging of myocardial oedema following acute myocardial infarction: Is whole heart coverage necessary?

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Using the Stanford-Binet Intelligence Scale: IV, scores in each of the four domains assessed by this battery (Verbal Reasoning, Abstract/Visual Reasoning, Quantitative and Short-Term Memory), as well as the general composite score, ranged from moderately mentally retarded to low average. The intravenous injection of maximum terazosin dose one component within 120 min after the injection of the other component killed mice. Thuridan was the most effective out of the tested insecticides in reducing the number of the insects.

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Propranolol was the most effective agent with reported benefit in four of six cases, other antimigraine agents were deemed effective in two of seven cases. Collagen with gentamicin for prophylaxis of postoperative infection. The ESD procedure is the treatment of choice cefpodoxime complicated uti antibiotics for rectal carcinoids that have classic histologic architecture with minimal cellular pleomorphism and sparse mitoses, but it has not been applied for such tumors. Clinical value of quantitative immunochemical determinations of various proteins in the cerebrospinal fluid

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Iron(III)/ascorbate toxicity miracid dosage was completely prevented with the hydrogen peroxide detoxifying enzyme catalase and partially prevented with the antioxidant vitamin E. Complementary data derived from each approach show that CENH3 localizes not only to the primary constriction, but also in the pericentric regions and is distributed exclusively in the interior, rather than on the surface, of the centromere. Evaluation of algorithms for analysis of NMR relaxation decay curves. Ventricular beta-adrenoceptor density was found to be significantly depressed in membrane preparations from both diabetic and ISO-treated groups relative to controls.