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Echocardiographic investigations were performed in 26 type 1 diabetic patients evaluated for kidney transplantation and the results compared with those obtained in healthy controls and in a similar group of patients investigated in 1977-1980. GEC-targeted HO-1 expression reduces proteinuria in glomerular immune injury. In vitro phosphorylation of vitamin B12 dependent methionine synthase by protein kinase A. Changes in gene expression in the brain in response to adverse conditions, such as ischemia or excitotoxin exposure, may be part of the injury process or represent an adaptive response which may be protective during subsequent stressful events.

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Reflective fiber-optic refractometer based on a thin-core fiber tailored Bragg grating reflection. Use of two artificial sweeteners, cyclamate and acesulfame, to identify and quantify wastewater contributions in a karst spring.

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No significant biomicroscopic signs of ocular surface toxicity were noted. Evaluation of isoquinoline alkaloid supplementation levels on ruminal fermentation, characteristics of digestion, and microbial protein synthesis in steers fed a high-energy diet.

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Together, these findings provide insights into the essential processes leading to polarization of the actin cytoskeleton. Therefore, an increase in osmolality per se cannot be responsible for the observed changes of motility.

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Immunocytochemical demonstration of growth hormone, prolactin and somatostatin-like immunoreactivities in the brain of larval, young adult and upstream migrant adult sea lamprey, Petromyzon marinus. Domain III of the basement membrane proteoglycan perlecan was produced as three overlapping fragments in stably transfected mammalian cell clones.

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These probes did not, however, hybridize under high stringency conditions to DNA prepared from uninfected bovine lymphoblasts, T. Furthermore, investigators have recently proposed particular tips and parameters to serve as reliable predictors of successful and durable PVI that may enhance the clinical success of this single-shot ablation technique. Eco-evo-devo of the lemur syndrome: did adaptive behavioral plasticity get canalized in a large primate radiation?

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Enoyl-CoA hydratase and isomerase form a superfamily with a common active-site glutamate residue. The association of birthweight with length at 12 mo and with height at different ages was assessed in a sample of 260 healthy adolescents (130 boys and 130 girls). This report documents that the pancreatic adenocarcinoma cell line, HPAF, contains oncogene activity detected by transformation of NIH 3T3 cells through transfection with HPAF DNA.

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Inhibition of angiotensin-converting enzyme by enalapril treatment had similar effects, prior to the loss of weight. Phytolith analysis on dental calculus, enamel surface, and burial soil: information about diet and paleoenvironment. Advances in MRI techniques may further elucidate the pathology of MS, thus providing opportunities for new treatment strategies. The method collects the aerosol in a midget impinger containing dimethyl formamide, which inhibits the curing reaction between the epoxy and curing agent, preserving the unreacted epoxy functional groups present in the aerosol. Detection of Human Papillomavirus Infections at the Single-Cell Level.

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Further studies are needed to show whether treatment of hyperlidaemia in this population delays the onset or slows the progression of CAVD. Analysis of ECOG performance status in head and neck squamous cell carcinoma patients: association with sociodemographical and clinical factors, and overall survival. The concept of a single rate-limiting step was proven to be too simplistic for understanding control and regulation of metabolism. Radioimmunoassay of the ovine folliculo-stimulating hormone (FSH)

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Changes of mitochondrial NADH(2) oxidation pathways in Torulopsis utilis grown on acetate. Findings on microdissection of specimens of medullary sponge kidney showed uniform enlargement of collecting tubules in part of the papillae. Modulators of the renin-angiotensin-aldosterone system and cough in childhood. Effects of RNA silencing of matrix metalloproteinase-2 on the growth of esophageal carcinoma cells in vivo.

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At laparotomy, a soft, retroperitoneal mass was seen between the stomach and the left adrenal gland, measuring 5.5 x 2.5 x 2 cm. To assess anatomical and functional characteristics of renal artery aneurysms, renal angiogram, MRI, intravenous pyelography, ultrasonography and radionuclide renography were performed. Various diagnostic criteria, such as skeletal relation, arch-length analysis, inclination of teeth, and dental esthetics, must be evaluated. Our results support the conclusion that determination of CI, BMI and WC alone is insufficient to assess the risk of CAD and mortality in the general population.

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The strain failed to grow on nonfermentable carbon sources such as glycerol at low temperature (20 degrees C). Aetiology of Angiofibromas: Reflection on their Specific Vascular Component

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Multiple excrescences and a solid tumour in the left parametrium were found consistent with solid pseudopapillary neoplasia. In addition, a WSN deployment algorithm is presented with topology control and scoring mechanisms to maintain network connectivity and improve sensing coverage rate.

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As the elastic recoil was normal and did not change after H, it could not explain delta FRC at delta SGaw of -40 percent. Size and shape of the optic disc, neuroretinal rim, optic cup, and alpha and beta zones of parapapillary atrophy. Therefore, C2C12 cells provide the first in vitro model system to study various aspects of GH action in skeletal muscle. A neural network model of speech acquisition and motor equivalent speech production. Overexpression of the alpha1B-adrenergic receptor causes apoptotic neurodegeneration: multiple system atrophy.

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Neurological FIP, which is much more homogeneous than systemic effusive or noneffusive FIP, appears to be a good model for establishing the basic features of FIP immunopathogenesis. First 3-D structure determination of a peptide oxazol-5(4H)-one with a chiral protein amino acid in the heterocyclic moiety: an x-ray diffraction analysis of the enantiomeric and racemic Goodman oxazolone.

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The degenerative osteoarthritis (DOA) is a common disease of aged people. Differential effects of milrinone and dobutamine on right ventricular preload, afterload and systolic performance in congestive heart failure secondary to ischemic or idiopathic dilated cardiomyopathy. coli bacteria, grown in yeast extract-tryptone medium, originates from L-serine deaminase, and the remainging ten percent from the degradative L-threonine deaminase.(d) Conditions have been established in which threonine deaminases are eliminated and the activity of L-serine deaminase alone could be measured, even in crude extracts.

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This ratio allows one to measure accurately the enzymatic activity in the presence of chemical or biological inhibitors. In a model study, cancer cells seeded at the frequency of 1 per 106 and 1 per 107 leukocytes were detected in CD45- population. However, metastases may have radiopharmacokinetics different from normal thyroid tissue. Discontinuation of chronic treatment disrupted unpunished responding only on the first day, and reversed the increase in punished responding. Minority Response to Health Insurance Coverage for Mental Health Services.

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Examination of carcinoma cells for the subcellular localization and pH optimum of Gly-Pro-MCA hydrolase activity revealed that the activity of a lysosomal enzyme that hydrolyzes Gly-Pro-MCA at pH 6.4 was markedly increased in carcinoma cells, but not in normal cells. Antibody production was assessed by measurement of total immunoglobulins and of specific antibody production against polysaccharide and protein antigens, with test immunisation if necessary. B-cell epitopes in HIV-1 Tat and Rev proteins colocalize with T-cell epitopes and with functional domains. Experience at the Massachusetts General Hospital (MGH) with resections for primary lung carcinoma is brought up to the clinical staging era (1971) with a 5 year cumulative survival statistic of 30 percent for the period 1964 through 1970. The increase of cellular phospholipid hydroperoxide preceded the cytotoxicity.

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Consistent with the model, a structural equations analysis indicated that DUI and RWDD were primarily predicted by (a) expectancies regarding the physical risks of DUI, (b) normative beliefs about the extent to which friends would disapprove of DUI, (c) control beliefs about the ease or difficulty of avoiding DUI and RWDD and (d) drinking. Preoperative imaging studies will often be adequate to identify these anomalies, but interpreting radiologists may not be aware of its clinical significance.

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Lnk is a representative of a multigene adaptor protein family whose members act, by analogy with Lnk, to modulate intracellular signaling. The aim of this study was to investigate whether Etk is involved in the chemoresistance of small cell lung cancer (SCLC) and to correlate the drug resistance associated proteins such as bcl-2, bcl-X(L) and p53. A simple genealogical process is found for samples from a metapopulation, which is a population that is subdivided into a large number of demes, each of which is subject to extinction and recolonization and receives migrants from other demes.

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Femur length showed significant linkage with loci on proximal chromosome 3 (lod 6.1), and suggestive linkage with a locus on chromosome 14. The attachment of sister kinetochores by microtubules emanating from opposite spindle poles establishes chromosome bipolar attachment, which generates tension on chromosomes and is essential for sister-chromatid segregation. Selective destruction of cultured dopaminergic neurons from fetal rat mesencephalon by 1-methyl-4-phenylpyridinium: cytochemical and morphological evidence. Superoxide radical production in brain slices of 12-, 24- and 60-day-old rats was measured online during and after 15 min of hypoxia with lucigenin enhanced chemiluminescence. Progress in investigation of the mechanisms underlying embryogenesis is related to the discovery of genic families in the Drosophila genome, which are responsible for different periods of embryogenesis.

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Human colon carcinoma cells, isogenic except for the presence or absence of either p21WAF1 or 14-3-3sigma (T. The property and violent offenders were surprisingly similar to each other in childhood experiences, family problems, and psychiatric diagnoses. In poorly-differentiated tumors, aspirate was also abundant but usually blood-free and contained isolated sharply polymorphous tumor cells.

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The effect of DSP-4 at 3 days is similar to treatments that act to inhibit noradrenergic function such as administration of the alpha 1-antagonist, prazosin, or the alpha 2-agonist, clonidine. Pheromone responses and high-level aminoglycoside resistance of conjugative plasmids of Enterococcus faecalis from Greece. DNA which was extracted from throat swabs, together with known copy numbers of a cloned VZV DNA fragment, were 10-fold serially diluted and used as template in PCR.

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Prostaglandin E(2) inhibits IL-18-induced ICAM-1 and B7.2 expression through EP2/EP4 receptors in human peripheral blood mononuclear cells. 5-Hydroxytryptamine-containing enterochromaffin cells: storage site of substance P. It is believed that serum levels of superoxide dismutase may play a role in etiology of autism. Simply, a drug can interfere with the normal cardiac action by modifying an ion channel function at the plasma membrane level leading to abnormal repolarization and/or depolarization of the heart cells thus precipitating a disruption in the rhythm and causing dysfunction in contractions and/or relaxations of myocytes. This finding confirms that haemorrhoidal disease may be regarded as a manifestation of a soft tissue disease.

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As a complementary method to transcriptomics and proteomics, approaches for isotopomer-assisted analysis of metabolic pathways contain three major steps (2). However, severe limitations of the stimulated echo acquisition mode occur, which are related to the special dynamic properties of the beating heart and flowing blood. Pain in both patients was similar in that it was bilateral, symmetric, burning in quality, and aggravated by external stimuli, mainly light touch. Reduction of environmental tobacco smoke exposure in asthmatic children.

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HL-1 cells were exposed to plasma isolated from burned or sham rats. Highly cited articles in environmental and occupational health, 1919-1960. Flexion-distraction injuries of the lumbar spine and associated abdominal trauma. Effects of a decision support system on the diagnostic accuracy of users: a preliminary report.

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We address shock waves generated upon the interaction of tilted plane waves with negative refractive index defects in defocusing media with linear gain and two-photon absorption. PRO staff developed a chart abstraction tool and trained hospital abstractors who collected and submitted data to the PRO for comparative analyses. Although further evaluation is necessary, Sactimed-I-Sinald appears a promising alternative to glutaraldehyde. In such cases the brain damage can lead to a childhood-onset localization-related symptomatic occipital epilepsy.

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In addition to high dose radiation-induced meningiomas, intracranial meningiomas were observed in patients who underwent low-dose radiation for tinea capitis in childhood, applied en mass to immigrants coming to Israel from the North Africa and the Middle East during the 1950. Enterococcus faecalis was susceptible to ciprofloxacin and to ofloxacin, but Enterococcus durans was moderately resistant to these agents. Interviews were undertaken with 20 people with a history of buru spirit possession and 30 of their family members. pylori relationship in subjects with non-ulcer dyspepsia and a histological diagnosis of gastritis. Furthermore, both the mutant and the wild-type protein colocalized with snRNPs.

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Our data show that some class II molecules (A alpha, A beta) can induce very efficient rejection, while others are relatively inert (E), and that tolerance induction requires matching for both chains of the target class II heterodimers. Sixty-four patients had a transurethral resection, 22 patients a prostatectomy and 83 patients had only a biopsy. Sequence organization of a cloned tDNA met fragment from Xenopus laevis.

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Ureterosigmoidostomy: an outdated approach to bladder exstrophy? It is concluded that the BANG gel dosimetry offers the potential for measuring the 3D dose distributions of an ophthalmologic applicator, with high spatial resolution and relatively good accuracy.

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Unique T cell effector functions elicited by Plasmodium falciparum epitopes in malaria-exposed Africans tested by three T cell assays. The experimental results indicate that a proper relative stereochemistry at C2 and C6 in l-proline-derived bifunctional organocatalysts is important for successful catalysis and that catalysts (PTU and PU) with the 2S,6R configuration are much more efficient. In a previous study, advanced fibrosis was associated with worsening efficacy of antiviral therapy in HCV-transplant patients. To address this problem, a diet and activity intervention during pregnancy, which was based on social learning theory, was initiated in 4 Cree communities.

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Ube3a loss increases excitability and blunts orientation tuning in the visual cortex of Angelman syndrome model mice. To obtain optimal estimators (uniformly minimum variance unbiased estimators) for the quantities inside the clusters, goodness of fit tests must be performed.

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