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To explore the possibility of utilizing valproyl derivatives of GABA and glycine as new antiepileptics by using the structure pharmacokinetic-pharmacodynamic relationship (SPPR) approach. Psychometric properties of this symptom score are evaluated and suggestions provided for increased involvement for urologic nurses in its clinical application and future development. Endosonographic follow-up after local excision of a pT1 rectal carcinoma. Evidence that abnormalities of central neurohormonal systems are key to understanding fibromyalgia and chronic fatigue syndrome.

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We also find that neurogenic genes are required for the specification of the mesectoderm. Herds selected were enrolled in the New York Dairy Herd Improvement Cooperative program and received monthly or biweekly herd health visits from the New York State College of Veterinary Medicine. Additionally, presynaptic relationship probably occurred between the 5-HT and its innervated DA pathways. Training was provided first to CCWs from the intervention cluster (IC) followed by the control cluster (CC). Plasmids are self-replicating extrachromosomal DNA molecules found in Gram-negative and Gram-positive bacteria as well as in some yeast and other fungi.

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Structural analysis of the EGFR TK domain and potential implications for EGFR targeted therapy. These causes have complex interrelationships that are not well understood. We report on 2 Turkish families with children who had bilateral anophthalmia, upper and lower limb abnormalities, mental retardation and consanguineous parents. Two scenarios are investigated using (1) multiple wavelength-division-multiplexed channels with sufficient power of the pilot tones and (2) a single channel with a low-power pilot tone.

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Quantitative study of anti-streptolysin O activity of human IgG myeloma protein To analyze the safety and accuracy of ultrasound-guided (USG) percutaneous needle biopsy of the spleen.

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Effect of paternal smoking on the pulmonary functions of adolescent males. The direct extension of a neoplastic thrombus of the pulmonary veins into the left atrium is extremely rare. A control group received a saline injection instead of idazoxan. In future, this mutation may be targeted with antisense-therapy aiming at exclusion of the pseudoexon. Evidence of saxitoxin derivatives as causative agents in the 1997 mass mortality of monk seals in the Cape Blanc Peninsula.

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These findings imply that errors in mean skin temperature measurement could arise from probe mislocation and/or subcutaneous fat distribution and that the problem becomes more acute with increasing cold stress. Response of the bear to fluoxetine treatment indicated that pharmacologic manipulation of the serotonergic system can safely eliminate stereotypical behaviors in captive polar bears.

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Examination of electrophysiological maps of evoked movements suggests that the mode of recovery (re-acquisition of pre-infarct movement strategies vs development of compensatory movement strategies) may be related to the relative size of the lesion and its specific location within the M1 hand representation. Circadian time of treatment affected TMZ sensitivity of murine GBM tumor cells in vitro. Degree of stability of characterstic properties of bacteria preserved in mineral oil Focal cellular origin and regulation of interstitial collagenase (matrix metalloproteinase-1) are related to menstrual breakdown in the human endometrium. A single serotonergic modulatory cell can mediate reinforcement in the withdrawal network of the terrestrial snail.

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Conservative management is appropriate for uncomplicated acute ischemic proctosigmoiditis. A comparison of six enrichment media for isolating Salmonella pullorum from egg-products. Substrate utilization by Campylobacter jejuni and Campylobacter coli.

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This pseudomeningocele occurred in a patient after an L3 burst fracture associated with a dural laceration. Familial deletion in Becker type muscular dystrophy within the pXJ region. To develop such a model we have injected human myoblasts into the tibialis anterior of SCID mice after inducing necrosis. There is also evidence suggesting that lithium augmentation of tricyclic or serotonergic antidepressants and the combination of a serotonergic and noradrenergic antidepressant may hasten response. It should be considered the treatment of choice in the initial management of esophageal narrowing and appears to be safer than the more traditional methods of esophageal dilation.

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We present a real-time FRET-based method for probing the reaction cycle of chaperone-proteases, which consists of substrate unfolding, translocation into the protease and degradation. We demonstrate that HopZ1a is an acetyltransferase activated by the eukaryotic co-factor phytic acid. From these data, I estimated visits for acne and drugs prescribed during these visits. Furthermore, some of the OxLDL effects appear to be mediated by the nuclear receptors retinoid X receptor and peroxisomal proliferator-activated receptor gamma because pretreatment of THP-1 macrophages with ligands for these receptors, followed by LPS treatment, recapitulates the OxLDL plus LPS results for several of the most significantly modulated genes.

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Vascular hemorrhage was considered as low flow when the hematoma appeared as a focal homogeneous density area and as high flow when associated with contrast agent extravasation. This study aimed to determine the prevalence of autism spectrum disorder (ASD) by using the Autism Diagnostic Observation Schedule-Generic (ADOS-G) classifications in children born very preterm during their toddler years. Screening of Candida albicans fluconazole--resistant mutation strains

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Unusually high prevalence rates of obesity in four Mexican rural communities. Through this study, we also determined that the cathodic activity of quinone derivatives during the discharging process relies strongly on the solvation effect as well as on the number of carbonyl groups available for further Li binding. We cloned a human gene termed PIG-B (phosphatidylinositol glycan of complementation class B) that is involved in transferring the third mannose. Gastric trichobezoar in a banner-tailed kangaroo rat (Dipodomys spectabilis). Full interpretation of these data requires structural information.

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UNC-83 is a nuclear-specific cargo adaptor for kinesin-1-mediated nuclear migration. Reduction in fecal microbiota diversity and short-chain fatty acid producers in Methicillin-resistant Staphylococcus aureus infected individuals as revealed by PacBio single molecule, real-time sequencing technology. Moreover, we study the scale dependence of the number of members of the reduced set, the number of ground state candidates, and the number of perfectly stable sequences by comparing the results for sequences with lengths of 6 up to 20.

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Endocrine function of the testes in experiments on Papio hamadryas Reversible dinitrophenylation of glyceraldehyde 3-phosphate dehydrogenase. The risk of complacency must be recognised, especially when there is a high rate of co-existing conditions.

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With respect to Roentgen stereophotogrammetric analysis, sagittal plane rotation was determined by distortion-compensated Roentgen analysis with an error (standard deviation) of 1.4 degrees and a mean difference of less than 0.05 degree. We performed a MEDLINE search of literature published from 1966 to 2000 for studies addressing the use of dopamine in the prevention and/or treatment of renal dysfunction.

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Cellular release of the lactoferrin measured by ELISA supported the results of immunohistochemistry. The transfer of DNA from Agrobacterium tumefaciens into a plant cell requires the activities of several virulence (vir) genes that reside on the tumor-inducing (Ti) plasmid. Despite the large difference in cytochrome P-450 induction by CloTZ, MCZ, and TCZ, these agents elevated p-nitroanisole demethylase and aniline hydroxylase to similar extents (3-5 X and 1-2 X control, respectively). Home care packages: insights into the experiences of older people leading up to the introduction of consumer directed care in Australia. Seroepidemiology of HTLV-I in relation to that of HIV-1 in the Gauteng region, South Africa, using dried blood spots on filter papers.

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pylori is associated with a significant reduction in the relapse rate of peptic ulcers, but there are few reports about long-term outcome. The aim of this review was to analyze the current knowledge regarding the significance of selected biomarkers in cancer angiogenesis, with emphasis on their prognostic value in the circulation.

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Influence of lens status on graft and visual outcome in a corneal graft register. The Maori of New Zealand have been shown to be at greater risk of illness and death than their non-Maori counterparts. The VP2 hypervariable region of infectious bursal disease virus (IBDV) from nine Mainland Chinese strains was amplified by reverse transcriptase/nested polymerase chain reaction and cloned into pGEM-T vector. Inclusion criteria will be broad with respect to type of work, as we will include all types of research studies as well as non-research studies that provide information relevant to characteristics and constructs measured in the context of integrated care for youth mental health.

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Congenital rhabdomyosarcoma, central precocious puberty, hemihypertrophy and hypophosphatemic rickets associated with epidermal nevus syndrome. Development of a brief version of the Burn Specific Health Scale (BSHS-B). Elective stent placement in small coronary arteries with focal de novo lesions is safe and associated with a marked reduction in restenosis rate and subsequent target lesion revascularization rate at 6 months. Eight men and 12 women (mean age 55 years) with severely damaged kidneys underwent laparoscopic retroperitoneal nephrectomy.

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The effect of manual bulb pump infusion systems on venous luminal pressure and vein wall integrity. The questionnaire was distributed by mail and self-completed by participants.

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The use of nasal swabs was shown to be as accurate but significantly less painful than nasopharyngeal swabs for virus diagnosis. ELISA and immunoblot analysis clearly demonstrate the secretion of human kappa- and gamma-1 chain. Detection of herpes simplex virus DNA in tear fluid of stromal herpetic keratitis patients by nested polymerase chain reaction. A national model for participative management and policy development. Retinoic acid and thyroid hormone regulate placental lactogen expression in human trophoblast cells.

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Comparative study of conventional colonoscopy, magnifying chromoendoscopy, and magnifying narrow-band imaging systems in the differential diagnosis of small colonic polyps between trainee and experienced endoscopist. Purification and properties of UDPG dehydrogenase from beef liver. To study the association between adiponectin plasma levels, and gray matter brain volume and cerebral glucose metabolism in a group of type 2 diabetes patients. Simplification of dynamic NMR spectroscopy by wavelet transforms.

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To localize and evaluate the expression of ZO-1 in the normal human pancreas, in pancreatic ductal adenocarcinoma (PDAC), and in chronic pancreatitis (CP). The concrete structure-activity relationship was observed that dihydroxylated 2,4,6-triphenyl pyridines with hydroxyl group at meta or para position of 2-phenyl ring displayed significant topoisomerase II inhibitory activity as well as cytotoxicity. The suture of the anastomosis was done with unresorptive material (Prolene 6/0).

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Abnormal opening of the common bile duct into a duodenal diverticulum The present experiment explores the feasibility of conducting fMRI studies in nondemented and demented older adults by measuring hemodynamic response properties in an event-related design. High-performance liquid affinity chromatography and in situ fluorescent labeling on thin-layer chromatography of glycosphingolipids.

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Hyperglycemia has been linked to an increase in the morbidity and mortality among patients who undergo cardiac surgery, and the benefits of correcting hyperglycemia in this setting by means of intensive insulin therapy are well documented. The purpose of this study was to determine the parental understanding of the multiple consequences of transplantation.

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In this study, six novel thaumatin-like proteins (TLPs) were identified in western white pine (Pinus monticola) needle apoplast by a proteomic strategy using two-dimensional protein electrophoresis followed by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. Balloon valvotomy did not result in significant mitral regurgitation.

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We investigated whether impalpable, invisible (stage T1c) but significant prostate cancer can be detected better by determining the free-to-total prostate specific antigen (PSA) ratio of equivocal PSA serum levels. Therefore, our diagnosis was urachal transitional cell carcinoma and right ureteral carcinoma.

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When immune animals were challenged with homologous virus, they failed to become virus carriers again and no rises in neutralizing antibodies were detected. Closed-Loop Control of Postprandial Glycemia Using an Insulin-on-Board Limitation Through Continuous Action on Glucose Target. GPs were generally positive about CRP POCT, and they felt that it empowered them to safely prescribe fewer antibiotics for LRTI without alienating their patients. SEAs were prepared from eggs of a South African (SA), Eastern Caprivian (EC) and Puerto Rican (PR) isolate, separated by SDS-PAGE, stained and the molecular masses of constituent polypeptides determined. The method enabled the medical record abstractors to ascertain cases for the study.

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Moreover, sequence analysis of the VP7 gene was performed on seven samples (one stool, two serum, three cerebrospinal fluid, and 1 throat swab sample). Human leukocyte antigen class I (A, B and C) allele and haplotype variation in a South African Indian population. Oesophageal perforation and the limitations of the difficult airway algorithm in small neonates are discussed. The effects of cerebellar ataxia on sign language production: a case study. In this work, we evaluated the expectation and variance of the within-population variance of the allele size distribution in a finite population, and the expected homozygosity at a locus by the coalescence approach under a general stepwise mutation model, where mutational transitions of allele sizes can be arbitrary, including being asymmetric.

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Finally, in valvular aortic stenosis, aortic valve replacement restores normal diastolic function. Cyclodextrin (CD) is one kind of widely applied host molecule, and the host-guest interactions between CD and different counterparts can respond to different stimuli and thus can be applied as responsive linkers for polymeric DDSs.

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We provide a comprehensive perspective of the role of currently available instrumentation, summarize the work in our center regarding the technological developments of magnetic resonance imaging, and speculate about future applications of magnetic resonance imaging systems for evaluation of velopharyngeal dysfunction. Modification of lipoproteins by oxidation or glycation significantly affected the capacity of lipoproteins to induce prostacyclin (PGI2) production by bovine aortic endothelial cells (BAEC). Using, in Southern blot analysis, a DNA probe from the type 1 fimbrial switch, that hybridized to one DNA band from phase-on bacteria and to two DNA bands from phase-off bacteria, we found that the three clinical isolates expressing type 1 fimbriae contained the same invertible switch previously seen in the K-12 isolate. Characterization of novel metallo-proteases released from ascidian hemocytes by treatment with calcium ionophore.

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Preventing possible severe complication of progressive abscesses of the head and the neck an additional parenteral antibiotic therapy in high doses combined with the surgical treatment is recommended. The data were analyzed by nonlinear regression in a microcomputer and it was found that they fitted a model of a moderate cooperative dimer where both ES and ES2 are catalytically active. Unlike conventional therapeutic approaches, anti-angiogenic therapy holds the unique promise of treating the disease in the absence of cytotoxicity or drug resistance. Polymeric optodes based on upconverting nanorods for fluorescent measurements of pH and metal ions in blood samples.

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This hepatomegaly was ascribed primarily to individual cell swelling. In vivo administration of interleukin 2 plus T cell-depleted syngeneic marrow prevents graft-versus-host disease mortality and permits alloengraftment. Five indices of potential developmental toxicity are: the proportion of pregnant survivors at term that produces a viable litter (at least one liveborn pup), average litter size and pup weight at birth, and average neonatal survival and body weight gain to 3 days of age. Extensive homology of inferred 282-aa sequence to peptidyl-propyl cis/trans isomerase C (PPIase C) of E. We manipulated brood size, measured feeding effort of both males and females, and assessed the prevalence of the hemoparasite from blood smears.

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Appearances on T2- and proton density-weighted images and occurrence of incidental high-signal foci. The gene was located on the translocated chromosome segments of Leymus mollis.

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A questionnaire-based study of the occupational exposures and residential histories of the cases was also carried out. After 6- day infusion, intrathecal morphine challenge test (5 microg/10 microl) was performed, and time-response curve was constructed to assess the magnitude of tolerance. In direct comparisons with the amplified ELISA, RT-PCR shows an increase in sensitivity detecting 11 fg of purified virus. Four weeks later, the function of cardiac sensory inputs to the ICNS was studied by applying veratridine (7.5 micromol/L) to ventricular sensory fields. Prevalence and clinicopathological features of H3.3 G34-mutant high-grade gliomas: a retrospective study of 411 consecutive glioma cases in a single institution.

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Melanization is an effective defence reaction used by mosquito hosts to kill malarial and filarial worm parasites. We set out to determine if the mechanism of estradiol action on E-selectin is at the level of its promoter. Females of the shield bug Parastrachia japonensis Scott progressively provision nymph-containing nests with drupes of the host tree, Schoepfia jasminodora (Olicaceae: Rosidae: Santales). In this review, we summarize the applications of liver-derived organoids and discuss their potential. Computed tomography demonstrated a primarily hyperdense calcified suprasellar space-occupying lesion.