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The history culminates with the successful mitral valve replacement, performed by Albert Starr using a mechanical valve designed by him and Lowell Edwards, a retired engineer whose primary interest was to develop an artificial heart. Among 11 Croatian players authors discovered one with a history of GI symptoms and one with conversion of negative to positive test for occult bleeding in stool after the match.

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In conclusion, oxLDL-driven foam cells are enriched with leukotriene-synthesizing lipid bodies--specialized organelles whose biogenic process is mediated by MCP-1/CCL2-triggered CCR2 activation and ERK-dependent downstream signaling--that may amplify inflammatory mediator production in atherosclerosis. However, both MUC1 and ezrin had a similar overall distribution pattern in microvilli and filopodium-like protrusions in immunoelectron tomography. The mouse Nedd4 protein, a membrane-localized ubiquitin ligase containing multiple WW domains, was identified from this screen. RNAi in mice, through the expression of short hairpin RNAs (shRNAs), offers something not easily achieved with traditional genetic approaches-inducible and reversible gene silencing.

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A molecular genetic linkage map of mouse chromosome 13 anchored by the beige (bg) and satin (sa) loci. Breast cancer is the leading cause of cancer death amongst Singapore women. In this study, we investigated the effectiveness of hyperbaric oxygen (HBO2) therapy on the acute lung injury induced by venous air infusion in rats. Two new aromatic constitutents from the rootwood of Aeschynomene mimosifolia. Moreover, the architecture of the database and the web application is flexible and can be easily adapted to store data related to other proteins with point mutations.

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As more children with complex cardiac anomalies are accepted for primary surgical repair or palliation with cavopulmonary anastomoses, a knowledge of coronary sinus and systemic venous anomalies is important if coronary venous return is to be preserved and residual shunts avoided. Inhibition of esterase activity and an undercounting of circulating monocytes in a population of production workers.

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One of the major advantages of this type of procedure is the ability to adjust the sutures during the operation. Anatomo-clinical notes on lipoid nephrosis and nephropathies with renal lipoidosis 54th annual meeting of the Japanese Association for Thoracic Surgery. In vitro, when fluoride is added before exposure to the light, it can protect some cell types against photodynamic action sensitized by chloroaluminium phthalocyanine (AIPc) and its derivatives. Gd(DTPA-BMA) and a prototype of macromolecular contrast agent, albumin-(Gd-DTPA), were used as controls.

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Alterations of the cyclin-dependent kinase inhibitor p19 (INK4D) is rare in hematopoietic malignancies. The overall patterns of diversity shown by molecular and serological analyses were similar: East-African isolates differed from West-African ones, and the West-African isolates from forest differed from the savannah ones.

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Ataxia with isolated vitamin E deficiency: case report and review of the literature. Hand-assisted technique facilitates preserving graft viability in laparoscopic donor nephrectomy. Nine days after the surgical procedures, all rats were infected with 35 cysticercoids of H. We report on a case of primary leiomyosarcoma of the patella in a 59-year-old woman.

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The aim of this study was to compare the effect of root biomodification by lasers, citric acid and antimicrobial photodynamic therapy (aPDT) on viability and proliferation of human gingival fibroblasts (FGH). Multilevel determinants of teenage childbearing in sub-Saharan Africa in the context of HIV/AIDS. However, understanding this diversity in relation to adaptation and environmental variation is a challenge for which tools are now available.

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In this work, we used observations of mRNA expression and promoter sequence to analyze signatures of selection on groups of functionally related genes in Saccharomycete yeasts. Several hormones and proteins regulate channel activity, but the molecular nature of this regulation is unknown. The objective of this study is to develop data processing methods, which can be used to process movement data into relevant metrics for the evaluation of intra-patient differences in quality of movements in a daily life setting. The author described the epidemics that happened in Poland in the eighteenth century as well as the methods of treatment and prophylaxis at that time.

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When metalloporphyrins are in excess, they aggregate at the BSA surface, up to two MnTPPS4, and up to 10-15 FeTPPS4 units per BSA globule. Regardless of the model employed, dietary and plasma arginine were the main precursors for citrulline synthesis during feeding and plasma arginine during feed deprivation.

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As inferred from ERG measurements, the S-cone pigment of the chimpanzee has a spectral peak of about 430 nm. Funding for a national critical care nursing education research study. Collectively our data showed that the decrease in host fitness was coupled with, and potentially mediated by, symbiont loss at 30 degrees C.

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Most of the patients were primiparous and HELLP syndrome recurred in 2 during a second gestation before 32 weeks gestation. There were no statistically significant differences in mean maxillary GBF between patients having the DPA ligated and those having the DPA preserved as measured using LDF during Le Fort I osteotomy. Relaxin concentrations (in serum) were measured by radioimmunoassay. The sorption mechanisms and complex formation between humic acid (HA) and a successively increasing number of diethyl phthalate (DEP) molecules have been studied theoretically using molecular mechanics, the number (n) of DEP molecules being varied from 1 to 30.

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Among the 23 blood group systems presently identified, almost all have a molecular basis and present investigations are oriented towards the analysis of genetic polymorphisms, tissue-specific expression and structure-function relationships. The results suggest that targeting patients who are less literate or who smoke could allow for taking the required measures to prevent or control depression at the end of a CR program. Limited power in the design restricted the capacity to detect differential treatment effects.

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Active-site amino acid sequence explains substrate specificity compared with liver isozymes. Bacillus sporothermodurans produces highly heat-resistant endospores, that can survive under ultra-high temperature. Protein and calorie malnutrition is associated with a reduction in plasma cholinesterase activity and enhanced cocaine toxicity in mice. In this article, we suggest four questions that can be used to guide the monitoring and evaluation of policy or programme options.

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An accepted conventional wisdom exists for Indian tribes that they are undernourished and away from lifestyle-related diseases. Recognition of individual EBV gene products by bulk CTL lines was evaluated by combining CTL lines with B cell blasts infected with recombinant vaccinia constructs expressing single latent genes. The utility of the CCK DISIDA scan in the treatment of occult biliary tract disease.

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Present investigation may support basis toward the future possibility of prognostic test realization, which can provide a personal choice of immunomodulatory treatment for a patient with multiple sclerosis. This conclusion was supported by the fact that the majority of mast cells developed by c-kit ligand contained only tryptase in their granules, whereas those developed in the cocultures contained both tryptase and chymase. One-stage posterior reduction eggshell osteotomy can be used to correct a sagittal and/or coronal congenital spinal curve imbalance.

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The purpose of this paper is to describe and discuss a significant secular trend in stature and weight in an urban Brazilian population. A total of 146 samples of five species of fish were examined between March and November 1986 in four sites from the Rivers Brett and Chelmer in eastern England. This will require a concerted effort to bring these products to market.

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Plasma, urine and tumour samples were assayed for total radioactivity, and for parent compounds by HPLC. Recent work indicates an intimate interaction of the tryptophan catabolite (TRYCAT) pathways with the melatonergic pathways, primarily via TRYCAT pathway induction taking tryptophan away from the production of serotonin, which is a necessary precursor for the melatonergic pathways.

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In conclusion, replicating results of several potentially useful tests and their predictive validity of actual driving impairment should deserve further research. We have analyzed how translocation intermediates of imported mitochondrial precursor proteins, which span contact sites, interact with the mitochondrial membranes. Educating every teacher, every year: the public schools and parents of children with ADHD. Effects of ovariectomy and hormone replacement on DRL behavior in the rat.

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This review will give an update on the potential of pancreas transplantation, give a guide for clinical practice and help to consider pancreas transplantation as an alternative to insulin treatment for selected patients. Bioinformatics analysis of the prognostic value of Tripartite Motif 28 in breast cancer.

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An ossified pelvic fin basipterygium discovered in the arthrodire Incisoscutum ritchiei was hypothesized to be identical in males and females, with males presumed to have an additional cartilaginous element or series forming a clasper. Considering the affinity of both molecules for CD28 (T cell receptor for B7-1 and B7-2), we postulated that their potential to augment IL-2 antitumor activity would be similar. Norwalk-like virus outbreaks at two summer camps--Wisconsin, June 2001.

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As examples of applications, rotation-invariant descriptors based on polar and spherical Fourier coefficients are tested on pattern classification problems. Lichen planus and lupus erythematosus may occur as an overlap syndrome. The resetting of a somatic epigenotype to a totipotential state has been demonstrated by successful animal cloning, via transplantation of somatic nuclei into enucleated oocytes.

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The physical and chemical properties of the mosquito coil, a commonly used mosquito repellent in Asia and South America, were analysed. More black than Hispanic or non-Hispanic white patients used herbal therapies and spiritual healing. Data on treatment intensity and severity of medical late effects were collected via chart review.

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These extrinsic signals are capable of directly or indirectly influencing the suppressive capacity of Bregs, but also their expansion and functional restoration in its absence. The recombinant eukaryotic expression plasmid pSCEPBFCAT was transfected into human fetal tendon fibroblasts in culture to realize ectopic expression of hBDNF gene in fibroblasts.

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Although CHRNA5 polymorphism is rare from Japanese lung cancer, polymorphism status might be correlated with shorter survival. Regulation of collagenolysis and cell death by plasmin within the formative stigma of preovulatory ovine follicles.

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The changes in vascular reactivity observed in L-NAME-induced hypertensive rats may play an important role in the pathogenesis of this type of hypertension. Disseminated intravascular coagulation and thrombotic microangiopathy can produce thrombotic or hemorrhagic complications.

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Ipecac-induced emesis and gastric lavage are equally unpleasant. It is becoming ever more difficult for thoracic surgeons to justify not using a VATS in the face of overwhelming evidence for the benefits of this approach - not only in terms of reducing patient morbidity, but also in improving surgical outcomes. A neurite-stimulating effect was induced by both the cerebrospinal fluid of epileptic patients and the media of co-cultures of rat hippocampus and chick embryo sensory neurons after veratridine treatment. The resulting peptide fragments were separated by HPLC and sequence information for individual fragments was obtained. The results show a high level of stability of PC under gastric and duodenal digestion conditions.

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Nephrotoxic insults which pose little threat to the normal kidney may enhance progression in the diseased kidney. Acid reflux-induced oesophageal injury caused basal cell hyperplasia with an increase in cell proliferation and EGF-R expression.

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Data from the Health Care Financing Administration were merged with other sources at the county level. The distribution of opioid peptides is fairly consistent in the anterior hippocampus of these four species. An interaction between EGFR and A(1)R was detected using immunoprecipitation and immunocytochemistry. Advances in the treatment of sickle cell pain will depend on multiple approaches, including both pharmacologic and nonpharmacologic.

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This is likely to be a reflection, in part, of earlier and more comprehensive detection of child maltreatment on the part of nurse-visited families. Radiation-induced single-strand breaks in the DNA of spores and of vegetative cells of Bacillus subtilis were rejoined during postirradiation incubation. All dogs had a history and results of diagnostic testing suggestive of either primary (idiopathic) or occult secondary epilepsy.

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Calculation of rare-earth 4d giant-absorption spectra with multiplet effects and decay processes. Present in vitro study demonstrated that BZYQT is capable of increasing granulocyte colony-stimulating-factor (G-CSF) and tumor necrosis factor-alpha (TNF-alpha) production by peripheral blood mononuclear cells (PBMC) in healthy volunteers and patients with HCC. Genes on rat chromosomes 3, 5, 10, and 16 are linked with facets of metabolic syndrome. They also rely on the work of their nurses more than male doctors.

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Pronounced decreases in sugar responsiveness occurred after combined section of the chorda tympani (CT) and greater superficial petrosal nerves. A questionnaire written in English collected demographic data and included questions about reproductive health care and health rights of women and patients with cancer, senility, or special needs.

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Long-term implications of reocclusion on left ventricular size and function after successful thrombolysis for first anterior myocardial infarction. Potential disadvantages of gabapentin enacarbil include cost, concerns of suicide risk and pancreatic cancer, and a lack of data for the FDA-approved 600-mg dosage. The correlation between the tremor and the loading coincides with the results of psychophysical experiments (known as modified Veber-Fehner law), combining the organism reaction with the stimulation intensity. Biophysical studies of cell membranes A report of the British biophysical society meeting held in Birmingham on 15 and 16 April 1969. A Chemical-Genetic Approach to Generate Selective Covalent Inhibitors of Protein Kinases.

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12 anesthetized patients suffering from a cerebral arteriovenous malformation undergoing endovascular treatment. Changes in bladder capacity and voiding pressure were evaluated after intravenous administration of test compounds. FDA and EMA Need Homology on Alcohol Outcome Measures-Semper: Simplicitas est purius modum.

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The eazyplex MRSA assay was found to be a useful test for the rapid detection of S. We studied the effect of 30 mg/kg of methylprednisolone on the pulmonary vascular response to hypoxia in six late-gestation newborn lambs.

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The tumor was totally resected, and was pathologically diagnosed as a calvarial metastasis of the cervical carcinoma. Antitumor activity of blood monocytes and macrophages was discussed on a concept of the mononuclear phagocyte system.

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The pregnene derivatives with modifications at the 17,20-side chain and D-ring were synthesized and evaluated as inhibitors of human testicular 17 alpha-hydroxylase/C17,20-lyase. Impact of genome assembly status on ChIP-Seq and ChIP-PET data mapping. Microsatellite isolation using amplified fragment length polymorphism markers: no cloning, no screening. After target preparation using mixed titanium/iron oxides, the final sample was measured by compact accelerator mass spectrometry. The clinical characteristics of intra-acinar pulmonary artery inflammation and its effect on clinical parameters in smokers with normal lung function and patients with chronic obstructive pulmonary disease

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About 40 h after partial hepatectomy, very many small gap junctions reappeared in close association with the zonulae occludentes. Safety of Pregnancy After Cerebral Venous Thrombosis: A Systematic Review. Incomplete design of stent-graft system, rough handling and presence of vascular wall lesions are the main reasons of RAAD complicating TEVAR for TBAD. beta-Endorphin caused a dose-related limb rigidity that persisted for up to 2h.

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Sensor systems for lower limb functional electrical stimulation (FES) control. Consequently, the growth regulation of established tumours may differ from that in their original counterparts in the patients. It shows activity toward L-arabinitol, adonitol (ribitol), and xylitol with K(m) values of about 40 mM toward L-arabinitol and adonitol and about 180 mM toward xylitol. These results suggest that the purified material acts as an enhancer of u-PA in extracellular matrix of the cancer cells, inducing an effective tissue destruction and cell invasion and possessing a highly metastatic potential. Forty-five premolars autotransplanted to the maxillary incisor region in 40 adolescent patients were evaluated after a mean observation period of 4.0 years.

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Standardization of terminology and techniques used, combined with large prospective clinical studies, is required if detection of occult residual disease is to become a prognostic marker for recurrence in colorectal cancer. Managing the desire for better children through biotechnological enhancement. Simulating the generic source as a thin surface that radiates from both sides eliminates the presence of irregular frequencies in the analysis. The authors report case of a dural arterio-venous fistula fed exclusively by the external carotid artery. The outcome of the labors with normal and abnormal graphic patterns were compared.

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Among 13 cases, marked elevation of both indirect- and direct-reacting bilirubin levels was reported in 4 cases. In this report, we have investigated the effect of dietary exposure to Aroclor 1254 (1-100 ppm) given chronically or discontinuously over an 84-day time interval to the female F344 rat.