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These cells are easily cultured and expanded in vitro by standard techniques, providing an alternative source of osteogenic progenitor cells for possible cell-based therapeutic use in certain conditions. Effects of systematically depriving access to computer-based stimuli on choice responding with individuals with intellectual disabilities. We believe that ours is the largest blood biomarker study of preclinical AD to date. Regardless of size, ownership or corporate structure, the goal of the dialysis provider is to deliver the best renal substitution therapy in the safest and most convenient manner, at a cost commensurate with reimbursement.

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3 Tesla magnetic resonance imaging study of the normal canine femoral and sciatic nerves. Distal esophageal varices (one to four per session) were mechanically ligated using an elastic band ligature device attached to a flexible endoscope. We conducted a nationwide multicenter study in Japan to elucidate the clinical and laboratory characteristics of acute encephalitis with refractory, repetitive partial seizures (AERRPS). The findings suggest that cathepsin K, rather than neutral matrix metalloproteinases, degrades the superficial gliding surfaces of the articular hyaline cartilage in OA. Culmorin has low toxicity in several in vitro assays and in one study in swine and is Ames test negative.

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Dissecting aneurysm of the superior mesenteric artery: flow dynamics by color Doppler sonography. All patients undergoing thoracotomy after induction chemotherapy from 1993 through 1999 were reviewed.

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Regulation and control of compartmentalized glycolysis in bloodstream form Trypanosoma brucei. Neural network mechanisms of oscillatory brain states: characterization using simultaneous multi-single neuron recordings. The data were compared to sham stimulation and to 1 Hz single TMS.

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In addition, most providers are not equally efficient in managing different chronic illnesses. Accelerated s-nitrosothiol breakdown by amyotrophic lateral sclerosis mutant copper,zinc-superoxide dismutase. Refined multivalent display of bacterial spore-binding peptides. This study was a randomized controlled clinical trial conducted in the Department of Periodontics and Oral Implantology, KIDS, Bhubaneswar, Odisha.

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Reactivation of hepatitis B after organ transplantation in hepatitis B surface antigen (HBsAg) carriers may be fatal. A two-way analysis of variance (ANOVA) was performed to determine the statistical significance of differences in cerebral metabolite concentrations among subject groups and brain regions. Future research needs to be conducted to investigate the effectiveness of BI for patients with diabetes. Four loci were identified that affect dorsal-ventral patterning of the brain, including the previously described cyclops locus.

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This study describes a novel method for increasing the immunogenicity of autologous tumor vaccines in leukemia and lymphoma patients by exploiting the natural anti-Gal antibody for in situ targeting of the vaccinating cells to antigen-presenting cells (APCs). Targeted NK-92 cells have advantages over many systemic therapies including their specific cytotoxicity to malignant cells (particularly those expressing the target antigen), ability to spare healthy cells, and being unaffected by efflux channels.

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This is an epileptic syndrome commonly associated with treatment-resistant seizures, being also the most prevalent form of drug-resistant epilepsy which is treated surgically in most epilepsy surgery centers. Multivariable logistic regression models were used to test the association of BMI with RCC histology.

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The influence of adrenocorticosteroids on seizures and wet dog shakes (WDS) induced by deep prepyriform cortex kindling was studied by bilateral adrenalectomy and corticosterone replacement. The North-South information highway: case studies of publication access among health researchers in resource-poor countries.

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In this article a recently qualified physician, now in family practice in the USA, gives expression to the widely held view that a new breed of general practitioner with expanded roles and skills is required if the health-for-all targets are to be attained. Biomass samples taken during the continuous operation of thermophilic anaerobic digestors fed with manure and exposed to successive inhibitory pulses of long-chain fatty acids (LCFA) were characterized in terms of specific metabolic activities and 16S rDNA DGGE profiling of the microbial community structure.

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The peanut plant can resist fungal attacks by producing stilbene-derived phytoalexins. Selective up-regulation of CD36 with interferon-gamma (IFN-gamma) increased PRBC adherence. Adolescence is an age when the causes of the disease, which may operate from birth, overlap with the major etiological factors in the generality of pancreatitis in adult life.

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In this investigation, serosal receptors of the intestine were stimulated by bradykinin in anesthetized cats to 1) compare mesenteric and renal sympathetic responses, 2) compare hemodynamic responses in mesenteric and renal beds, and 3) determine changes in renal function. Operative treatment of the severe deformations of the lower extremities in osteochondrodystrophy. The phenotype of the disease varies from mild skin symptoms to lethal forms of the disease. The model considers effects of both selective and nonselective channel losses on saturation processing based on the assumption that disease produces elevated thresholds while maintaining normal psychometric response functions.

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Here we have investigated nerve growth factor (NGF) concentrations in the basal forebrain, prefrontal cortex and hippocampus of both male and female offspring at 11 days of age. In mitotic nuclei, differential staining of sister chromatids made it possible to distinguish cells that had gone through one, two and three or more proliferation cycles.

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Prevalence survey of infection in a Hong Kong hospital using a standard protocol and microcomputer data analysis. The survey data were analyzed with age and sex standardization to generate 1-year prevalence rates of major depression. The importance of proper eye protection in sports is also discussed. The selective use of immunosuppressants, such as tacrolimus, that have neutral or fewer adverse effects on lipid metabolism may also provide a useful option. Two different types of melanocyte were observed: i) The first (Type A) was characterized by spherical, uniformly pigmented stage IV melanosomes.

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Results showed for the first time that such co-precipitated coatings on anodized nanotubular titanium could release drug molecules for up to 3 weeks whereas previous studies have demonstrated only a 150-minute release of antibiotics through simple physical adsorption. These proteins engaged in a network of dynamic interactions that control apoptosis triggering have become attractive therapeutic targets in cancers including melanoma. To describe an unusual kindred with adult-onset ataxia and thalamic lesions detected by brain MRI.

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Incidence of lactase deficiency in patients with involution osteoporosis and in normal subjects. Higher chemosensitivity was associated with poor differentiation, aneuploidy, and higher proliferative activity. Three case studies are reviewed in which children with the diagnoses of imperforate hymen presented for evaluation of suspected sexual abuse. Concentration of blood free fatty acids during the pain caused by developing myocardial infarct

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The status quo and prospect of experimental study on channel tropism of Chinese herbal drugs IL-10 Accelerates Re-Endothelialization and Inhibits Post-Injury Intimal Hyperplasia following Carotid Artery Denudation. The mature human immunodeficiency virus type 1 protease rapidly folds into an enzymatically active stable dimer, exhibiting an intricate interplay between structure formation and dimerization. in conjunction with ovarian dysfunction must be classified as dysprolactinemia. The optimal condition of desmin mRNA detection was in cryostat sections fixed with paraformaldehyde and in paraffin embedded tissue with the same fixative.

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This suggests that the neurotoxicity of N-methyl-D-aspartate antagonists is due in part to the oxidative stress and may be amenable to therapeutic interventions. These findings disclose a novel regulatory pathway that is composed of HRCR, miR-223, and ARC. Using these methods, we have previously shown that contusion injury alone results in a chronic relapse in vascular permeability. An empirical study of the DSM-IV Defensive Functioning Scale in personality disordered patients.

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comosum, constitute the major exception to the equilocal model of satellite DNA and heterochromatin distribution. G3 has four inverted repeats, two 14-base direct repeats, and three ORFs. These studies demonstrate the ability of IL-6 treatment to enhance G-CSF-mediated acceleration of multilineage recovery following radiation-induced hemopoietic aplasia.

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In this paper, we review the literature concerning the phenotype in mouse and in humans, showing that at least 2 subsets of MDSCs are present under different situations. Spectrophotometric titrations of rabbit liver Cd7-MT 2, apoMT, and Cd4-alpha-domain with Cu(I) revealed endpoints of 3-4, 4 and 8, and 4 and 6-7 added Cu(I)/mol of MT for the three species respectively. In the presence of MAD-3, antibodies specific for peptides overlapping the nuclear location signal (NLS) sequences of p65 and p50 could not recognize their epitopes on NF-kappa B, suggesting that the I kappa B protein rendered the signals inaccessible for NLS receptors.

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To investigate the specific effects of dexfenfluramine (dF) as an adjunct to a reduced-fat, ad libitum diet. This study aims at evaluating the possible role of ultrasound scan in the assessment of subcutaneous lipohypertrophy in patients affected by type 1 diabetes mellitus.

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In normal neonatal glomeruli, once capillary loops were present, there was staining of GBM for the alpha 1-alpha 5 chains. Unrecognised fatal anaphylactic reaction to propofol or fentanyl. Multiple semen cryopreservations should be done during the first post-orchiectomy year.

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Data were evaluated by standard noncompartmental pharmacokinetic techniques. Data were obtained from 310 adult patients with mild, moderate, or severe asthma who were treated in the practice between January 1988 and June 1994 and who had been placed on nedocromil sodium for at least 1 year.

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Clinical use of the immunosuppressive drug azathioprine is limited by potentially serious toxic effects related to depression of bone marrow function. Our results demonstrate that both the human placental AT1 receptor content and the G alpha q/11 protein level increase during pregnancy, and suggest that the AT1 receptor pathway may play a role in human placental physiology.

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A prospective cohort study was conducted using 235 households (647 individuals) randomly selected from four rural hamlets. Effect of temperature on stability of marker constituents in Echinacea purpurea root formulations.

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It is difficult to reduce unstable fracture of the distal end of the radius in the way of close reduction. 55-year-old patient with edema and lymphadenopathy: significance of fine needle biopsy.

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Chronic diseases are on the increase due to changing life styles, and environmental pollution with mercury and persistent organic pollutants may pose a threat to future generations of Inuit. A 25-year-old man presented with a history of two episodes of lower gastrointestinal bleeding without transfusion.

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In an attempt to clarify the modes of liposome internalization, various kinds of inhibitors of endocytotic pathways were used to treat S. The results of our study suggest that a laparoscopic approach for patients with colorectal cancer with metastatic para-aortic lymph nodes can be a reasonable option for selected patients.

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Development of the cocaine relapse interview: an initial report. Spirulina, then to compare the antigenic reactivity of this new protein with that of Synechocystis and skeletal actins. In Experiment 3, random perturbations of vector magnitudes in general curvilinear fields did not reduce the accuracy of perceived heading.

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First, genetic factors that reduce endogenous sleep times might also impact energy stores, an assertion that we confirmed in a previous study. First, a synthetic peptide approach demonstrated that the inhibitory effect of leptin on basal and ACTH-stimulated corticosterone secretion in vitro is, at least partially, mapped to a domain of the native protein between amino acids 116 and 130, i.e.

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The past decade has witnessed an alarming increase in the number of deaths due to prescription opioids that has paralleled the rise in the number of opioid prescriptions dispensed. In an integrative approach, recent advances are reviewed on the consecutive topics of biosynthesis, storage, and release of insect AKHs, AKH signal transduction mechanisms and metabolic responses in fat body cells, and the dynamics of reversible lipophorin conversions in the insect blood. Xanomeline attenuated amphetamine-induced hyperactivity at doses that had no effect on spontaneous activity, possibly indicating a separation between attenuation of limbic hyperdopaminergic function and the induction of hypolocomotion.

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The coincident kinetics of IL-7 gene down regulation and apoptosis suggested that IL-7 gene expression may be required for maintenance of CLL viability in vivo. 1361 patients undergoing 1471 surgical procedures were subjected to a detailed and standardised preoperative assessment and classified according to ASA, age, procedure magnitude and RISK-VAS.

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In our study, 100 adults beginning outpatient psychiatric treatment completed the Sentence Completion Test of ego development and the Patient Request Form, which measures treatment modality preference. Contribution of writing to reading: Dissociation between cognitive and motor process in the left dorsal premotor cortex. These and other considerations, suggest H2O2 and other reactive oxygen species (ROS) could be the common factor in signalling pathways for diverse environmental stresses. Detection of trisomy 12 in chronic lymphatic leukemia (CLL) using polymerase chain reaction (PCR) and fluorescence in situ hybridization (FISH).

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Acute viral infections with combined involvement of the respiratory and gastrointestinal tracts in children. The five peptides, as well as an equimolar mixture thereof, lacked allergenic activity as demonstrated by basophil histamine release and skin test experiments in grass pollen allergic patients.

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The Schizosaccharomyces pombe aurora-related kinase Ark1 interacts with the inner centromere protein Pic1 and mediates chromosome segregation and cytokinesis. Physicians have a dual role in latex allergy--recognizing it in patients and, potentially, being patients themselves. We show that the number of aggregated particles displays a long-time power-law dependence with exponents that correspond to two different aggregation regimes. There was a substantial increase in the concentrations of lipid peroxides, malonic dialdehyde, and medium-weight molecules in the blood and a considerable decrease in its levels of vitamin E and the enzyme catalase.

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The metabotropic glutamate receptor mGluR1 is a G-protein-coupled glutamate receptor whose activation induces phosphotidylinositol hydrolysis and increases diacylglycerol and cytoplasmic calcium. When the animals were actively immunized with pili, still there were changes in the uptake of D-glucose and L-aspartate, but the changes appeared later and less pronounced. In patients with rheumatoid arthritis, hyaluronidase activity in the synovial fluid varied from not detectable to very high.

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Two policy issues related to intensive case management programs were examined: limiting caseload size to ensure that services are intensive and providing intensive services to the same clients in perpetuity. Comparison of binding properties and early biological effects of elicitins in tobacco cells The objectives of this study were to determine if monitoring of intraoperative somatosensory evoked potentials could be used to detect stroke during cardiac operations and to establish indicators of cerebral ischemia based on changes in these potentials.