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However, there is an evolving role for OCT in informing on non-ocular diseases, which ophthalmologists should be aware of. Ovarian vein catheterization studies revealed bilateral excess plasma testosterone and androstenedione secretion, and at surgery multiple dermoid cysts of both ovaries were found in association with polycystic ovaries. Tissue architecture in the Caenorhabditis elegans gonad depends on interactions among fibulin-1, type IV collagen and the ADAMTS extracellular protease. Selamectin is as effective as fipronil and imidacloprid in reducing C felis infestation in dogs housed for 3 months in a flea-infested environment under conditions known to support the flea life cycle, and in protecting against subsequent weekly challenges with C felis for an additional 2 months. Hard lenses, corneal and scleral, are still useful in correcting ametropia.

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Guanylate cyclase activity in fatty streaks was 1.5- to three-fold higher than in normal tissue. Forty-one patients (24 males, 17 females) with a median age of 26 yr and a median duration of inflammatory low back pain of 19 months were included. This historic shift reflects the increase in tobacco consumption worldwide, spurring public health efforts over the past several decades directed at tobacco cessation and control. The arrangement of the sigB-dtxR-galE cluster is also conserved in Corynebacterium diphtheriae. The Thyroid Registry: Clinical and Hormonal Characteristics of Adult Indian Patients with Hypothyroidism.

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Effects of drug concentration in inner aqueous phase and additives in oleaginous phase on release and bioavailability of isoniazid from multiple emulsion. The same perioperative protocol was implemented for all 6 patients. Pregnancy complicated by the HELLP syndrome and antiphospholipid antibodies has not previously been documented.

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Allergic airway eosinophilia is suppressed by cysteinyl leukotriene (CysLT) receptor (CysLT1 receptor) antagonists in several species including humans and guinea-pigs, suggesting that CysLTs are directly or indirectly involved in induction of the response. At present it is conceivable to think that gene therapy represents a way to treat or even prevent the respiratory manifestations of cystic fibrosis.

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This work will be helpful to decide an AD candidate for alkane biosynthesis in S. Stimulated mitogen-activated protein kinase is necessary but not sufficient for the mitogenic response to angiotensin II.

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The nodal ratio of positive to excised nodes is an alternative that could address this variability. Development of bioelectric activity in children 7 to 11 years old Using an airpump, pressure at the valve inlet was recorded at the point at which the valve opened, and at airflow rates of 20, 40, 60, 80 and 100 L.min-1.

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Mapping attractor fields in face space: the atypicality bias in face recognition. One hundred thirty-nine patients had posterior spinal fusion performed by 1 of 3 surgeons at our institution from 1987 to 1993. Screening for recombinant plasmids in yeast colonies of the two-hybrid system using PCR. S1(a) encodes 376 amino acids (aa) that contain partial exon 10 and a unique 39-aa C-terminal region encoded by exon 11. These results suggest that the content of alpha and delta subunits of CCT reduces from the complete active complex in S phase cells to incomplete inactive complex in M phase cells.

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The chemotherapeutic agent cisplatin was chemically linked to pGEM-3Zf(-) plasmid DNA to produce a cisplatin-DNA complex, Gold nanoparticles, which bind electrostatically to pure DNA, could also be added to this complex. In this latter case, neurites exhibit a straighter direction of extension. A combination of DNA sequencing of VWF genomic and complementary DNA was performed to identify mutations in the patient cohort. Cardiocirculatory disturbances led to fatal complications, the heart and brain infarction. First surgical management (local excision of T1N0M0 tumor of the right labia minora) was performed at the age of 16.5 years.

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Promising new therapies for the treatment of hypercholesterolemia. Down-regulation of phospho-AKT by RAF inhibitors also extends to downstream transcription factors, and correlates with apoptosis induction. Using a retrospective cohort design, we linked data on non-fatal heroin overdose cases obtained from ambulance attendance records in Melbourne, Australia over a 5-year period (2000-2005) with a national death register. This approach was considered better in applicability, comprehensibility and the creation of awareness. The KD mutants showed significantly altered expression patterns.

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However, detachment of seeded cells occurs following implantation. The degree of dosage increase in the immediate surrounding of metallic dental material was measured in an in-vivo study during therapeutic irradiation with 60Co gamma rays in the area of mouth cavity of 11 patients. Cytogenetic investigations of amphibian and rodent populations from the contaminated by radionuclides regions of Belarus was conducted. Comparison of three different operative procedures in forty-nine patients.

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Urinary symptoms and natural history of urinary continence after first-ever stroke--a longitudinal population-based study. Activated carbon particle adsorbed-peplomycin (PEP-CH) was administered to three patients who had advanced esophageal cancer and its clinical usefulness was evaluated. Aberrant crypt foci (ACFs) are putative preneoplastic lesions in the colonic mucosa identified by examining methylene blue-stained whole mounts of colon. Evaluation of microchip material and surface treatment options for IEF of allergenic milk proteins on microchips. Editing of glutamate receptor subunit B pre-mRNA in vitro by site-specific deamination of adenosine.

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These findings seem to represent an advantage for safety of retinol in relation to isotretinoin (13-cis-retinoic acid). Autism-like behaviours and germline transmission in transgenic monkeys overexpressing MeCP2. In addition, a compound eluting with the spectral properties of the aurone family is identified.

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A patient was followed for about 11 years from the onset of Perthes Disease (age 12). Prototropic control of intramolecular electron transfer in trimethylamine dehydrogenase.

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Furthermore, both clonidine and phenylephrine potentiated the plasma glucagon response to the cholinergic agonist carbachol and exerted additive stimulatory effects on the plasma glucagon response to both the beta-adrenoceptor agonist terbutaline and the C-terminal octapeptide of cholecystokinin, CCK-8. Variables reflecting heart dysfunction are important determinants of this risk. Impaired ability of glycated insulin to regulate plasma glucose and stimulate glucose transport and metabolism in mouse abdominal muscle. Peripheral type benzodiazepine binding sites are a sensitive indirect index of neuronal damage. However, residual articular cartilage GAG content was higher in serum-supplemented medium, as was GAG synthesis.

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Phase II trial of acivicin in patients with advanced epithelial ovarian carcinoma. To analyse the efficacy of fluticasone propionate (FP) alone and combined with salmeterol (SAL) in achieving guideline-defined asthma control in Asian patients. These results indicate that volatile anesthetic molecules have a specific affinity for neural tissue and that immobilization of anesthetic molecules in brain correlates with anesthetic potency. The viral macrophage inflammatory protein-II (vMIP-II) was conjugated to a biocompatible poly(methyl methacrylate)-core/polyethylene glycol-shell amphiphilic comblike nanoparticle through controlled conjugation and polymerization before radiolabeling with (64)Cu for PET imaging in an apolipoprotein E-deficient (ApoE(-/-)) mouse vascular injury model and a spontaneous ApoE(-/-) mouse atherosclerosis model. Calcitonin gene-related peptide: enteric and cardiovascular effects in the dog.

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The heterogeneity of these disorders are reflected by their varied clinical and neuroimaging features. Experiment 2 further showed that inference learners, unlike classification learners, were no better at classifying items that they had seen at study compared with equally typical items they had not seen at study. Solution-processable phosphorescent to organic light-emitting diodes based on chromophoric amphiphile/silica nanocomposite. The results thus indicate the involvement of TlOsm in plant response to multiple abiotic stresses, possibly through the signaling pathway, and highlight its potential applications for engineering crops with improved tolerance to cold, drought and salinity stress. The model provides behavioral and biological criteria with which to select the functional form and ranges of coefficients appropriate for a particular food web.

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Hydroelectric development and dietary delocalization in northern Manitoba, Canada. The objective of this study was to evaluate the long-term disease-free survival (DFS) and overall survival (OS) of MC.

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Typical dose escalation studies leading to the highest clinically still tolerated dose do not appear to be equally appropriate for the estimation of efficiency of those compounds as for conventional cytotoxic regimes. Calcium influx into vascular smooth muscle and/or endothelial cells for the display of hemodynamic action induced by nerve stimulation and the NA and PGF2 alpha effects, appear to occur through nifedipine-sensitive but verapamil-insensitive channels. The SKILL Card consists of two near acuity charts mounted back to back.

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Decreased production of extracellular proteins and cytoskeletal changes associated with lack of K14 expression are also likely to have contributed to the metastatic conversion of the RLE transformants. We performed this study to evaluate the clinical relevance of renal excretion of ingested Gastrografin (methylglucamine diatrizoate) revealed on CT in the early treatment of patients who have undergone gastric surgery. The aim of this study was to develop a conceptual framework of patient-reported NMIBC symptoms, treatment side effects, and HRQOL impacts from three sources: (1) literature, (2) patients and (3) treating clinicians. Analysis of 2M NaCl-extracted extracted BHK-nuclei, prepared on coverslips, showed that after brief pulses grains were exclusively found over the central core of the residual nuclei, which corresponds to positions in the nuclear matrix. Those compounds that emerged to be stable enough during preparation were tested for their in vitro hydrolysis rates.

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In contrast, when cells are stimulated with granulocyte macrophage colony-stimulating factor (GM-CSF), intracellular notch2 is not phosphorylated at these residues and differentiation is inhibited. This review summarizes the impact of 2D gel- and mass spectrometry-based proteomic approaches on a more comprehensive understanding of S.

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The low prevalence of EBV-positive cells suggests that local factors do not favor the entry and retention of circulating EBV-infected lymphocytes in gastric mucosa. The results provide unique MS/MS mapped fingerprints of mite species-specific isoforms in feces.

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In the present study, group B streptococci isolates from 57 patients with premature rupture of membranes were studied for fibronectin binding activities, using a particle agglutination assay and for cell surface hydrophobicity, by testing adhesion to hydrocarbons. This is believed to be regulated not by varying the disulfide bond itself, but by modulating the stability of the dithiol form of the protein through interactions with the ionized form of the Cys1 thiol group. However, activity generated by the isolated HE2 region in B cells is dependent on both an intact HAF-1/HAF-2 binding site and at least one additional site that has been reported previously to bind a B cell-restricted protein. Statistical Inference (part II): The Normal and Related Distributions. Wound healing in the skin requires a compromise between adhesion and migration.

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You make the diagnosis: a plan for long-term care based on the nursing theory of modeling and role-modeling. Second, we explore alternative means of justifying the use of reciprocity through appeal to different moral and political theoretical traditions (i.e., virtue ethics, deontology, and consequentialism). The impact of ligand binding on nuclear receptor (NR) structure and the ability of target cells to distinguish between different receptor-ligand complexes are key determinants of the pharmacological activity of NR ligands.

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The interaction between TTRAP and HIV-1 IN may be useful in designing new anti-viral strategies as well as for improving the efficiency of lentiviral-vector-mediated gene delivery. Increased levels of kynurenic acid in brains of genetically dystonic hamsters. Telencephalin (TLN) is a novel member of the Ig superfamily expressed in the central nervous system.

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The conventional method for testing male sexual behavior uses ovariectomized females rendered sexually receptive by injection of estradiol benzoate and progesterone prior to testing. Does the presence of thrombus seen on a coronary angiogram affect the outcome after percutaneous coronary angioplasty?

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I-site cleavage converts the enzyme to an active two-chain form consisting of the subunits An and Ac. Furthermore, I demonstrated that PTTG DNA binding is required for its transcriptional activation function. Levels of MMP-8 were analyzed in the tissues of PIs at weeks 0, 3, 6, and 9 by enzyme-linked immunosorbent assay. Priming stresses such as ischemic preconditioning or mild hyperthermia have frequently been associated with improved survival of ischemic-reperfused cardiac muscle, such protection coinciding with induction of the stress-related heat shock protein 70 (Hsp70).

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Using bilateral iliac branch devices for endovascular iliac aneurysm repair. This process of active segregation is poorly understood but in many instances has been shown to depend on the cytoskeleton.

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The 171 women who gave birth during February and March 1994 in the hospitals of the counties under study. Patients completed questionnaires that allowed reporting of both SD induced by the illness and the treatment, evaluating changes in libido, arousal, and orgasm. Acetylated derivatives of these peptides were prepared in order to further evaluate how positively charged primary amines contribute to potency in these small antimicrobial peptides. There are remarkable differences in work status and productivity costs between the three European countries.

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Hierarchical grid transformation is a powerful approach to SDS 2DPAGE maps warping. Recombinant classes within a 3-cM region around TRN1 were used to build a high-resolution map in this region, using the AFLP technique. From June 1, 1990 through December 30, 1993 the effectiveness of autotransfusion techniques with the additional use of postoperative infusion of salvaged blood was studied in 318 patients. To assess lysosomal membrane stability in gastric surface epithelial cells, we used laser scanning confocal microscopy to observe the fading of red fluorescence in living cells vitally stained with acridine orange.

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Immunoscreening with polyclonal antibodies raised against cell wall components allowed the detection of 29 positive clones. In this report the effects of external calcium and magnesium on the ciliary macroscopic current activated by cytoplasmic cyclic AMP were measured.

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Short time intervals between visual and magnetic stimulus induced a shortening, long intervals induced a prolongation of the reaction time. In vitro colonization of thymic primordia by adult bone marrow cells: light scatter profile and separation by flow cytometry. Six cases with posthrombotic obstruction of the pelvic veins are reported. This cell line should provide a valuable tool for further investigation of coherent aspects of proliferation and differentiation using various differentiation inducers. Sialylation and malignant potential in tumour cell glycosylation mutants.

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Synergistic activation of phosphoinositide hydrolysis induced in brain slices by norepinephrine and the excitatory amino acid agonist, trans-ACPD. These cells were subsequently seeded onto synthetic matrices fabricated from fibers (approximately 15 microns in diameter) of polyglycolic acid (PGA). Based on a MEDLINE search, we present a review of the current information on the epidemiology, pathogenesis, diagnosis and treatment of post-transplantation KS (PT-KS) with an emphasis on renal transplantation.

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We demonstrate the existence of common antigenic proteins between pine nut and peanuts. International amphibian micronucleus standardized procedure (ISO 21427-1) for in vivo evaluation of double-walled carbon nanotubes toxicity and genotoxicity in water. Stigmatisation of people with learning disabilities in general hospitals. Neocortical and hypothalamic EEG in non-deprived rats with pronounced attraction to alcohol consumption did not differ from the control. All patients were surgically treated, either conservatively or radically.

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Thiram-induced cytotoxicity is accompanied by a rapid and drastic oxidation of reduced glutathione with consecutive lipid peroxidation and cell death. A1PI was purified from Cohn fraction IV-1,4 using ethanol precipitation and Q-Sepharose chromatography.

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Physicians should not depend on a remote, computerized plan for diagnosis and treatment. Parents described less attention to their own physical health, dominance of the parenting role over all other roles, decreased social interactions, and a sense of personal satisfaction in response to placement of a child with DD in their homes. These findings demonstrate that Erb1p, like its mammalian counterpart Bop1, is required for formation of rRNA components of the large ribosome particles. Representation of visual space in area 7a neurons using the center of mass equation.

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The system is moreover able to transport DHFR into the lumen with methotrexate bound in the active site, demonstrating that the DeltapH-driven transport of large, native structures is possible by this pathway. Mitochondrial distribution in relation to changes in muscle metabolism in rat soleus. Yet, additional changes in skeletal muscle, blood flow and other mechanisms likely interact to modify insulin resistance with exercise training. To assess the myofibroblastic-epithelial interaction, frozen sections from a total of 10 endometrial cancers with or without invasive myofibroblasts were immunohistochemically examined. Recombinant human deoxyribonuclease (rhDNase), a new treatment in CF, depolymerizes DNA.

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Cells in the midbrain NMLF containing HRP-filled profiles were located bilaterally close to the midline and just beneath the ependyma. This is supported by the observation that chemical depalmitoylation of purified beta2AR did not affect the ability of the receptor to stimulate adenylyl cyclase in reconstitution assays. The potential clinical significance of the reverse-redistribution phenomenon in these two cases is discussed.

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Psychometric properties of the French version of the Modified Mini-Mental State (3MS) in elderly patients evaluated in geriatric psychiatry Whereas the low dose of 5-hydroxytryptamine (15 nmol.min-1.kg-1) had no haemodynamic effects, an increase in heart rate by approximately 20 beats/min, without change in blood pressure, was observed at the higher dose (60 nmol.min-1.kg-1). Mediated analyses showed that drug use, exchange of sex for money/drugs, unwanted sex, and to a lesser extent, problems with alcohol mediated the relationship between USC and unprotected sex acts, number of partners, and sex under the influence of drugs and alcohol.

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Hepatitis C virus: biological and clinical consequences of genetic heterogeneity. The increase of GDNF mRNA in the spinal cord mostly reflected an increase in the anterior horn, anterior and lateral columns, where the pathological involvement was severe.

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We report a case of angiofibroma confined to the pterygoid muscle plane without involvement of the sphenopalatine foramen or nasopharynx. The higher binding values were obtained at the level of the choroid plexus and above all of the hypothalamus. Psychological assessment of the patients showed no deviation from normal in premorbid personality but confirmed the severe adverse effects of the condition. A comparison of intratumoural indices of blood flow velocity and impedance for the diagnosis of ovarian cancer.

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MicroRNAs (miRNAs) are small regulators of gene expression that act on many different molecular and biochemical processes in eukaryotes. Effect of abacavir on acute changes in biomarkers associated with cardiovascular dysfunction. Visual evoked potentials to 4 stimulus intensities were recorded from Fz, Cz, and Oz, all referred to A2, in 23 neurologically normal subjects and 21 neurosurgical patients with prefrontal lesions.

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Twenty-five patients with coronary disease and ventricular dysfunction underwent low (5 and 10 micrograms/kg body weight per min) and high dose (maximum of 50 micrograms/kg per min) dobutamine echocardiography and positron emission tomography (PET) using nitrogen-13 (N-13) ammonia and fluorine-18 fluorodeoxyglucose (FDG) for imaging of perfusion and metabolism. Religious coping and cognitive symptoms of depression in elderly medical patients. The scaled model was designed to study the three-dimensional (3D) acoustic field in the presence of only a few propagating modes. Microdialysis of excitatory amino acids in the periaqueductal gray of the rat after unilateral peripheral inflammation.