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Using purified components and in vitro assays, we now demonstrate that HP1 forms a quaternary complex with the inner nuclear membrane protein LBR and a sub-set of core histones. Unexpected atrial fibrillation during tooth extraction in a sedated elderly patient. These results suggest that Elongin BC is a multifunctional regulatory complex capable of controlling multiple pathways in the cell through interaction with a short degenerate sequence motif found in many different proteins.

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CLN3 disease process: missense point mutations and protein depletion in vitro. Twenty-four dentin slabs were obtained from 8 healthy third molars and randomly divided into 3 groups, which were control group, casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) group, and nano-HA group. Transcription profiling, expression fingerprinting, and microarray analysis are terms that describe the cataloging of mRNA levels in a given tissue. Activities of lysosomal and cytoplasmic cholesterol esterases and cholesterol content in rat blood serum, liver tissue and aorta were studied after administration of ephedrine and propranolol. This accumulation of glycogen in megaloblasts, which are known to have disordered biosynthesis of DNA, RNA, and histones, suggests that carbohydrate metabolism may also be abnormal in vitamin B12 deficiency, perhaps as a result of an abnormality in the enzyme amylophosphorylase.

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The maternal placental blood flow in normotensive and hypertensive women. A high-grade heterologous pelvic sarcoma arose in a 60-year-old woman 15 years after she received whole-pelvic radiation for a low-grade endometrial stromal sarcoma.

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It is evident that the conventional technique for cochlear implant adjustment is not suitable for children in their first years of life. In this cadaveric study we assessed the level of the emergence of the musculocutanous nerve (MCN) relative to needle insertion site during infraclavicular block. These immunohistochemical results indicate that a few tumor cells of ASPS may express some properties of the cytoskeleton of smooth muscle cells in addition to those of skeletal muscle cells. 43 patients, not on class I or class III antiarrhythmic drug treatment, undergoing invasive electrophysiological testing had SAECG and T wave alternans measurements. A 16-year-old North American girl with a prior history of a bladder calculus removed by open cystolithotomy 8 years earlier, subsequently had squamous cell carcinoma of the bladder along the site of the previous incision.

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The effects of a 50:50 mixture of n-butyl and iso-butyl esters of 2,4-D (2,4-D mixed butyl esters, 150-175 mg/kg/day SC) on photocell locomotor activity and landing foot splay were assessed in rats. Action planning and position sense in children with Developmental Coordination Disorder.

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We evaluated the performance of the Pulsatility Index (PI) as well as the diastolic notch to predict recurring hypertensive disorders. Exposure of the developing primate fetus to exogenous glucocorticoid at 0.7 of gestation elevates fetal blood pressure. The fusion proteins were functional in transient expression studies in tobacco using either DNA bombardment or potato virus X as a vector, and in stably transformed Arabidopsis thaliana and Lotus japonicus plants. Treatment with CGS 12970 prior to and during gentamicin administration prevented increases in urinary TXB2 excretion and reduced nephrotoxicosis. Professor Wojciech Roeske (1916-2001: honorary member of the Polish Society of Medical History and Pharmacy

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These results suggest that generalized epilepsy in early life and functional deficits in the temporal neocortices may be associated with communication delays, and that functional imbalance in subcortical circuits may be associated with stereotypical behaviors and impaired social interaction in children with TSC. The retarded and first-grade groups spent more time completing mazes than did the other groups.

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Testosterone concentrations were measured both before and after human chorionic gonadotropin challenge in the Irish wolfhounds. The study included 1051 consecutive patients, 316 with unstable angina, 583 with Q wave acute myocardial infarction (AMI) and 152 with non-Q wave AMI. The unrestricted use of antibiotics has resulted in rapid acquisition of antibiotic resistance (AR) and spread of multidrug-resistant (MDR) bacterial pathogens. However, high consanguinity rates in populations with carrier frequencies as much as 1:5 may account for the occurrence of FMF in two or more successive generations, so-called pseudodominant inheritance. The results suggest that in order to collect accurate data for gait analysis, subjects should be familiarized to the split-belt treadmill for at least 5 min prior to data collection.