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Healthcare information technology (HIT) is being offered as a transformer of modern healthcare delivery systems. Catalepsy was inhibited in an inverted U-shape dose-response relationship with the maximal effect of each peptide occurring at 1.0 mg/kg. Annexin I mRNA expression was detected in the keratinizing squamous cells in keratotic type seborrhoeic keratosis and in keratinocytes at the periphery of the horn pearl in well-differentiated squamous cell carcinoma. Further workup may include a search for coagulopathies, less common sources of embolism, and intracranial intravascular disease.

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Our data do not support a pharmacological effect of statins on vitamin D status, but do suggest that vitamin D may influence plasma lipid profile and thus be of importance to cardiovascular health. These results indicate that early ABEP peaks, generated peripheral to binaural convergence, may be affected by contralateral stimulation. Activation of malEp and malKp, two divergent promoters from Escherichia coli, depends on the synergistic action of MalT and CRP.

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Two measures of fitness were made for each line: productivity (a combined measure of fecundity and egg-to-adult survivorship) and competitive male mating success. miR398 and miR408 are up-regulated in response to water deficit in Medicago truncatula. A unilateral parenchymal haemorrhage associated with a germinal matrix-intraventricular haemorrhage (GMH-IVH) is still an important problem in the preterm infant and especially in those who are very immature. Scores on the WI and Health Anxiety subscale of the IAS declined significantly from general medical outpatients, through general practice patients to subjects from the general population.

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T and B lymphocyte functions were investigated in the course of a long-term trial of recombinant human erythropoietin in patients with progressing multiple myeloma. The group pair fed to rats fed conventional diets, eight rats per litter, had an incidence and frequency of tumors between the other two groups. While the disease grow progressing the indexes of common hepatic blood flow and its components lowers, hyperdynamic state of splenic circulation changes to congested one. DNA ligase III alpha and III beta share a common NH(2) terminus that encodes a mitochondrial localization signal capable of targeting green fluorescent protein to mitochondria while the NH(2) terminus of DNA ligase IV does not.

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Effectiveness of a Computer-facilitated, Pharmacist-driven Antimicrobial Stewardship Program for Infection Management. Preoperative detection of distal intramural spread of lower rectal carcinoma using transrectal ultrasonography. A monoclonal antibody Lec101B, specific for MR60, recognizes a single M(r) 60,000 protein by Western blotting.

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The positioning for different oblique views in conventional radiography and technical details of computed tomography are reviewed. The -5C allele of the GP Ibalpha Kozak polymorphism may represent a risk factor in clinical conditions in which thrombosis plays an important role, such as in acute coronary syndromes and in complications after PTCA.

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Histological observation of the urogenital papillae in the bi-directional sex-changing gobiid fish, Trimma okinawae. The purpose of this study is to examine the bending profiles of composite resin coating cast clasps. Asymmetric spatial distributions of motion vectors yield characteristic errors in direction judgements. After sealing, the latencies elicited by a 6 kHz stimulus increased, but returned to normal between 24 h and 7 days after closure.

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Mesenchymal stem cells (MSC), given their ability to differentiate among multiple lineages, could potentially be used to treat diseases such as osteogenesis imperfecta, muscular dystrophy, and a variety of others that can be diagnosed in utero. Together with other favorable clinical factors, including prior parenchymal hemorrhage and neurosurgical intervention, the residual AVM spontaneously regressed in 2 months. For the introduction of small oligonucleotide gene therapeutics into a target cell, nanoparticle-based methods have been shown to be highly effective and safe.

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The data indicate that there are tensions experienced by members of the health care organisation when a hybrid clinician manager appears to abandon the managerial role for the clinical role. Antiarrhythmics Versus Implantable Defibrillators (AVID)--rationale, design, and methods. Ongoing method development efforts involve in vitro functional toxicology assays, screens for estrogenic activity, and carcinogenesis studies in transgenic mice.

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Strong enhancement of HLA class 1 surface expression by incomplete cytomegalovirus particles: analysis by dual-color flow cytometry using saponin. Electrocardiographic indices in the radiation therapy of lung cancer

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The interface between denuded dentin and regenerative periodontal tissue was investigated in a rat alveolar bone defect model using morphological and immunocytochemical approaches. Both insulin-stimulated phosphorylation and activity of PDK-1 were inhibited by wortmannin and reversed by treatment with the phosphatase PP-2A.

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A 68-yr-old man developed a tracheogastric fistula after esophageal resection with gastric interposition. Furthermore, the recent demonstration of a circadian pattern in the efficacy of tissue plasminogen activator, with peak efficacy occurring at 2000 hours--10 hours after the peak incidence of myocardial infarction--implies that further patterns to coronary artery syndromes may be predicted and the treatment efficacy may rely on demonstrated circaseptan and circannual cycles of these events. There were no differences in 8 epi-prostaglandin F2alpha, lipid peroxide or malondialdehyde levels between the groups of women with pre-eclampsia and those acting as pregnant controls.

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A further evolution of the smoothing spline method is considered as well. A new contact eatometer designed and built in our laboratory is described. Stress-activated protein kinase (SAPK) pathway-regulating phosphatase 1 (SKRP1) has been identified as a member of the mitogen-activated protein kinase (MAPK) phosphatase (MKP) family that interacts physically with the MAPK kinase (MAPKK) MKK7, a c-Jun N-terminal kinase (JNK) activator, and inactivates the MAPK JNK pathway.

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Public health dentistry, with its emphasis on prevention, can lend guidance and leadership at the primary, secondary, and tertiary levels. In a logistic regression model, depressive mood and subjective awareness of akathisia appeared to be the only predictors of suicidality and depersonalization, respectively. The surgical complications reportedly include hemorrhage, esophageal perforation, gastric perforation, and vagus nerve damage. Sulindac therapy of colorectal polyps in familial adenomatous polyposis.

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Localization of N-methyl-D-aspartate NR2B subunits on primary sensory neurons that give rise to small-caliber sciatic nerve fibers in rats. Triple factors of OYL, OPLL and listhesis contributed the cervical canal stenosis limited at cervicothoracic junction. This process may be caused by physiologic factors that lead to rupture of a vulnerable plaque and subsequent thrombosis. Reticular thalamic region in the rabbit: organisation of efferents to the superior colliculus.

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Targeting Insulin Receptor in Breast Cancer Using Small Engineered Protein Scaffolds. The purpose of this study was to compare the degree and timing of peak hepatic enhancement, optimal scanning intervals, and optimal delay times of moderate-rate uniphasic and biphasic contrast material injection protocols for hepatic helical CT.

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In an analysis of successive serum samples from infants at the day of birth and at the ages of 1 and 5 months, and at 1 and 2 years, the serum concentration of MBP increased significantly after birth, and was at its highest (the mean and median were 8.13 and 8.49 mgl-1, respectively) at the age of 1 month. A number of intravesical agents are reviewed in this paper along with the available evidence for their use.

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The study material comprised 25 lateral skull x-rays taken as part of routine orthodontic assessment. At short-term follow-up, a significant decrease in LV ejection fraction and LV global strain was noted as a consequence of changes in loading conditions. Genetic variation of the serotonin transporter (SCL6A4, 5-HTT) has been associated with fear- and anxiety-related behaviors, while a polymorphism in exon III of the D4 dopamine receptor gene (DRD4) has been linked to novelty seeking. In these mice, virtually all of the thymic epithelial cells (TEC) were deficient for Stat3 activation.

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The development of a computerised data handling and analysis system to aid the operation of a health and management program for commercial dairy herds is described. From October 1995 through August 1996, influenza activity occurred at moderate to severe levels worldwide. The results indicate that: 1) CCK-33 enhances the influence of catecholamines: noradrenaline and isoprenaline, mainly on the function of isolated heart. In an analysis of subgroups, we compared the separate contributions of treatment of a pretendinous cord and a first web cord on both extension deficit and IMD. Clinical research on AIH has benefited greatly from observations of experimental AIH in mice.

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Organotypic cultures of prepubertal mouse testes: a method to study androgen action in sertoli cells while preserving their natural environment. Equilibrium and oscillations of grains in the dust-plasma crystal.

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The strain was likely laboratory derived and contaminated the environment before it caused the infection. Analysis of two metabolic trait-associated coding polymorphisms in the human TM6SF2 gene (rs58542926 and rs187429064) revealed that both variants impact TM6SF2 expression by affecting the rate of protein turnover. Recent experiments suggest that some glycoprotein (GP)-specific monoclonal antibodies (MAbs) can protect experimental animals against the filovirus Ebola virus (EBOV).

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Schizophrenia is commonly associated with impairments in pre-attentive change detection, as represented by reduced mismatch negativity (MMN). The stacked pairs are stabilized by dispersion attraction, however, the mutual orientation of stacked bases is determined rather by the electrostatic energy. Laparoscopic diagnosis and management of an acute jejunal diverticulitis. Patients undergoing resection of a primary colorectal cancer were included in this study.

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