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Over a 1-year period, 92 patients qualified for the study, 24 of whom survived, 69 of whom suffered multiple organ failure syndrome, and 68 of whom died. In the cerebellum, ORL-1 immunoreactivity was only observed in the deep nuclei. The research was conducted in a laboratory setting and generalizability analysis was used as a statistical technique to identify the sources contributing to variation in the judgment outcome. The use of smaller peptides and fusion proteins including those spanning amino acids 28-93 and 5-93 has further narrowed the binding site to a region from amino acids 28 to 93, although participation of a sequence in the noncontiguous region 120-155 cannot be excluded.

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simulator) and the type of turn (right versus left) for any of the driving errors, indicating that the same trends exist between driving errors made on the road and in the simulator and thus suggesting relative validity of the simulator. Seven trained cyclists performed 30-s maximal isokinetic cycling trials using two crank lengths: 120 and 220 mm. Findings of this study are consistent with previous work showing clearance of mobile receptor-ligand complexes to the OCS of platelets activated in suspension. Epidemiology of nosocomial bloodstream infections in Belgium, 1992-1996.

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Expansion of the metaplastic foci occurred by addition of flattened, electron-dense secretory cells to the cap so that multiple layers of altered secretory cells covered a core of basal cells, analogous to the structure of an onion. It has been shown in vitro with human acidic gastric juice the nitrosomorpholine (NMOR) formation from small doses of precursors (sodium nitrite and morpholine) with a significant difference relative to the control. Drug abuse, a general public health problem, concerns a growing number of the pregnant women.

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We found that, when PCR reactions were run for 22 cycles, the amount of PCR products correlated closely with the amount of cDNA. Fine-needle aspiration (FNA) and pleural fluid cytology diagnosis of benign metastasizing pleomorphic adenoma of the parotid gland in the lung: a case report and review of literature. No adherence of meningococcus was observed when HeLa, HEp-2 or KB cells were used, but high rates of adherence to BEC occurred.

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According to a subfractionation of the mitochondria, the imported protein was found to be localized in the matrix space. AIRmax and AIRmin mice differ in their local acute inflammatory reactions to polyacrylamide beads (Biogel). We also analyze possible differences between distinct parts of the gene with different type of protein functions.

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Four population-based dynamic cohorts of residents aged 65 years and older (1999-2010) were included as subjects, 6 years before and after the intervention started. In remaining 14 animals who finally died on leukemia an 85 percent increase in life-span was noted.

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Zebrafish translation elongation factor EF1 alpha mRNA: sequence and secondary structures. CRX RT-PCR product from cells transfected with AODNs was greatly diminished following transfection with an AODN whereas control transcripts, including that of OTX2, were relatively unaffected. Conclusions Despite the positive evaluation of the participatory approach, the full program was executed less successfully compared to similar programs evaluated in earlier studies.

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Menopause-related symptoms: traditional Chinese medicine vs hormone therapy. Three-dimensional echocardiography for assessment of mitral valve regurgitation.

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Novocaine infiltration of the preaortic plexus in therapy of angina pectoris Maintenance of submersible pumps in the septic tanks: ergonomic and biological risks to the worker.

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Verapamil showed significant clinical benefits in patients with moderate intermittent claudication in this short-term study. Twenty-nine published articles were included in the final review. Consecutive patients with AF undergoing PVI and documented PFO were studied. Restriction analysis of otosclerosis-associated CD46 splicing variants. By means of these reflection coefficients an index for membrane fluidity has been given to each of those lipids, relative to that of egg phosphatidylcholine.

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Sequential MR examinations were performed in 17 patients with orbital pseudotumors, before and after treatment. ICI 185,282 is a specific thromboxane receptor antagonist developed by ZENECA Pharmaceuticals for potential use in the treatment of inflammatory disease.

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Initially, ventral motoneurone axons in the transitional zone are closely apposed to one another. Neglected dislocation of the patella with gonarthrosis, genu valgum, flexion, and external rotation deformity is rarely encountered. We compared Fos immunoreactivity (Fos-IR) in SCN and IGL neurons of rats housed under various lighting conditions and sacrificed at different phases of the circadian period. Lipoteichoic acid from Staphylococcus aureus induced expression of MMP-9 in human middle ear epithelial cells. The signal levels of the heart and diaphragm regions relative to the lung region of the phantom were significantly higher than in clinical chest radiographs (0.67 versus 0.21 and 0.28 versus 0.10 for the heart and diaphragm regions, respectively).

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The 15 autosomal STR plus 10 Y-STR kit in combination with capillary electrophoresis method was used to STR genotyping with accurate and reliable results. at this time, vitamin D supplementation is not warranted for the specific purpose of preventing pregnancy related hypertensive disorders. The evidence for brief interventions delivered to heavy alcohol users admitted to general hospital is still inconclusive. Additional magnesium and boron effects were evident in the measures of EEG coherence.

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Detectable antibiotic levels were present in umbilical blood and amniotic fluid within 15 min of maternal administration. Olfactory function was assessed prebiopsy and postbiopsy using the University of Pennsylvania Smell Identification Test (UPSIT). The centrally located transmitter domain of both forms of CheA contains four regions, called N, G1, F, and G2, highly conserved among histidine kinases of the family of two-component signal transduction systems. There is 20--36 percent decrease in the microsomal cytochrome P-450 (P450) content of the testes 3 or 6 h after CCl4 administration to Sprague--Dawley male rats.

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A cross-sectional analysis of the first 1,397 participants in baseline (before randomization) was performed. This library contains all the complete genomes from bacteria already sequenced and the yeast genome in GenBank format. Effects of a novel potential antidepressant on the behavior and cortisol levels of isolated guinea pig pups. Both patients showed blast cells possessing both lymphoid and myeloid characteristics, as demonstrated by histochemical, biochemical, or surface receptor properties of each cell series. Ultrastructural substrates for increased lung water content in experimental pulmonary edema.

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First North American 50 cc Total Artificial Heart Experience: Conversion from a 70 cc Total Artificial Heart. In this paper we review the literature on patient satisfaction with medical care and with their communication with the nursing staff. Subjects with normal hearing (42 ears) and patients with sensorineural hearing loss (30 ears) were also studied to obtain normative data. Twelve male Wistar rats were deprived of food for about 50 h, and 12 other rats were fed ad libitum. We sought to examine whether similar phases might characterize self-regulated cocaine use in humans.

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The moral vision of The Alchemist: tricks, psychotherapy, and personality traits. Sensory processing, cognitive processing, signal detection, criterion response, and user satisfaction were evaluated with controlled user testing and critical incident response techniques. Griffonia simplicifolia agglutinin-II staining following endo-beta-galactosidase digestion procedure revealed the presence of poly-N-acetyllactosamine structures with or without blood group-specificities in several normal human tissues. A conceptual scheme for assessing evenhandedness and (counter) self-serving attributional biases in relation to depression. We describe a 28-year-old woman presenting with hypokalemic myopathy caused by 17alpha-hydroxylase/17,20-lyase deficiency caused by a homozygous mutation consisting of a G-to-C transition in the initiation codon in exon 1 of the CYP17 gene resulting in expression of an enzymatically inactive truncated P450c17 protein.

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We find that TGF-beta 2 and -3 upregulate expression of the neural cell adhesion molecules NCAM and L1. Although it looks very unlikely to cure patients with larger tumour masses by either of these approaches, it might be feasible to treat bulky disease by conventional therapy first and then administer biological drugs to kill residual H-RS cells. The stereochemical course of the reaction mechanism of trehalose phosphorylase from Schizophyllum commune.

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Quantitative predictions for whole lung resistance and elastance agree with data from previously published studies on lung impedance. B9 also inhibited the binding of 7.12 to rabies virus both in vitro and in vivo.

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This study evaluates the feasibility of using PET as the sole source of target, normal structure, and applicator delineation for intracavitary GYN implant treatment planning. Based on the literature review, a novel Hamburg Per- and Intertrochanteric Fracture Score (HPIFS) is proposed to support decision-making for per- and intertrochanteric fracture treatment. Administration via chow of simvastatin (15 mg/kg of body weight/d) and lovastatin (43-55 mg/kg of body weight/d), both lipophilic, caused stunted growth, high creatine kinase (CK) activity in plasma, and severe myopathy. To date, most research has concentrated on the growth stimulatory factors. Endoscopic injection of gelatin solution for severe hemorrhagic gastric cancer.

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Effect of deviant probability and interstimulus/interdeviant interval on the auditory N1 and mismatch negativity in the cat auditory cortex. Favorable outcome was defined as three-month modified Rankin Scale (mRS) 0-3. The correlations among the variables revealed theoretically consistent interrelationships. The expression of cytochrome P450 3A4 (CYP3A4) in the foveolar epithelium of the human stomach with intestinal metaplasia was studied using immunohistochemistry, western blotting and reverse transcription polymerase chain reaction (RT-PCR).

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The occurrence of subsequent cancer was compared with the expected cancer pattern (which was determined on the basis of national incidence data). The size, extent, and anatomic topography of tissue lesions are depicted. Therefore, we aimed to determine whether metformin modifies the metabolic activity of the colon by increasing glucose uptake.

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Furthermore, the consequences of potential changes in aqueous humour properties induced by glaucoma filtration surgery have not been sufficiently addressed. Individuals with this variant present with bullous ichthyosis in early childhood and hyperkeratotic lichenified plaques in the flexural areas and extensor surfaces at later ages. A Markov model with a 1-year time horizon was developed to compare the cost benefit with and without the RISE program from a provider (hospital) perspective.

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Increasing treatment efficiency through effective intake interviews. Interpersonal problems as predictors of therapeutic alliance and symptom improvement in cognitive therapy for depression.

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Selective loss of natural killer T cells by apoptosis following infection with lymphocytic choriomeningitis virus. coli and raise the possibility that these proteins interact in a coiled-coil structure. Studies of cortical blood flow and microcirculation before, during, and after temporary occlusion of middle cerebral artery of squirrel monkeys.

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Therefore, considering appropriate biologic therapy as an adjunct to standard care against these damaging factors may provide rational expansion of treatment options for otolaryngologists and audiologists. This study assessed adolescent maternal psychopathology and its relation to the quality of mother-infant interactions. Specifically, subthreshold adaptation acts as a negative factor that observably decreases the neuronal dynamic range, while suprathreshold adaptation has little influence on the neuronal dynamic range.

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The aim was to examine agonist induced and myogenic venular responses after crystalloid cardioplegia in conditions simulating cardiopulmonary bypass. Two cases of arterioportal fistulas and new possibilities in diagnosis and treatment are reported: A 62-year-old women was admitted to our hospital with abdominal pain.

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It also revealed that all of the t-PA present in the culture medium formed complexes with PAI-1, indicating that AC-17 did not interfere with t-PA/PAI-1 complex formation. The main outcome measures looked for were the degree of pandemic preparedness, and the feasibility of currently proposed business continuity strategies.

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Relevant parameters on model characteristics and outcome measurement were scored on a standardized scoring sheet. This study was performed on phantoms and seven volunteers to determine the effects of MT at 3.0 T. The mechanisms by which stretch is transduced to a biochemical signal stimulating cell division have not been defined. We conclude that high-pressure freezing, combined with freeze-fracture and freeze-substitution processing techniques, is an excellent tool for studying the morphological aspects of exocytosis.

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Response time distributional evidence for distinct varieties of number attraction. Intraocular pressure in genetically distinct mice: an update and strain survey. Different cerebral areas representative of different levels of cerebral functional complexity were consistently activated and reproduced.

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It indicated that cAMP played a important role in mouse oocytes meiotic resumption. Studies on passive cutaneous anaphylaxis in the rat with disodium cromoglycate.

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CGS 10746B is the first atypical antipsychotic candidate that selectively decreases dopamine release. Neutrophil-specific annexin protein was identified by an immunological method. Anaerobic digestion of polyelectrolyte flocculated waste activated sludge. The mode of the distance between the innominate and left common carotid arteries was 5 mm and 6 mm, and the mode of the distance between the left common carotid artery and left subclavian artery was 8 mm.

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In this retrospective study using chart review as the reference standard, we calculated several estimates of the diagnostic accuracy of at least 1 ICD-9 code for HS. Chemical analysis of the purified human BUP showed 0.54 zinc atoms per subunit, and the sequence of BUP cDNA contained one putative zinc-binding site motif. Treatments already established in other aphasic states, such as post-stroke, may be especially relevant.

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Marked differences in extraction properties for the test analytes propranolol, anisic acid and ICI 128436 from aqueous buffer were noted between the two materials. Here we report that feeding juvenile female rhesus monkeys born and raised at the Wisconsin National Primate Research Center with a high-calorie diet results in acceleration of body growth and precocious menarche.

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The results indicate that lactoferrin may act as a potent anti-inflammatory protein at local sites of inflammation including the respiratory and gastrointestinal tracts. The effect of bosentan on endothelin-1 induced vasoconstriction was evaluated in isolated diagonal branches of left anterior descending coronary artery.

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After passage through the lamina propria, they enter crypt epithelial cells where they undergo several rounds of asexual and sexual proliferation, thus forming merozoites and later, gametocytes. Changes in milk composition during lactation in three species of insectivorous bats. In this study the level of DNA cross-linking and total DNA lesions formed by 1 a were measured by gene-specific Southern hybridization cross-linking assays and by quantitative PCR in cisplatin-sensitive (2008) and in cisplatin-resistant 2008/R human adenocarcinoma cell lines.

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Glycogen depletion contributes to ischemic preconditioning in the rat heart in vivo. Clinical course and laboratory findings correlated with relapses of systemic GvDH, thus suggesting the possibility that involvement of CNS and PNS may be sustained by a similar pathogenic mechanism. We studied the effect of incubating murine lymphocytes with cis-unsaturated fatty acids on expression and capping of CD44 and CD45.