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Mitral valve replacement in young children: a long-term follow-up The information encrypted in accurate peptide masses-improved protein identification and assistance in glycopeptide identification and characterization. Development of drug resistance is reduced with idarubicin relative to other anthracyclines.

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Mechanism of ethanol inhibition of NMDA receptor function in primary cultures of cerebral cortical cells. For rectal cancer, the risk decreased with an increase in the intake of carbohydrates as percentage of calories. Seven patients had syncope associated with sinus bradycardia, sinoatrial block or atrial fibrillation with slow ventricular rate.

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In the GPI, the results are more varied as the influence of the peptide bond modification seems to be more important than in the GPB. Mild to moderate suppression was seen in G 3 and G 4 with no difference between the two group.

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Highly vacuolated ILIR dendritic processes were also present in the neuropil. Families were unaware of the risk of HBV infection and feared vaccination. The specific Southeast Asian and Asian Indian tDNA versions can be found in companion articles in this issue of Current Diabetes Reports. AILI was repeated after 2 weeks and followed one week later by standard or extended-field radiation therapy (RT). Immunostaining for alpha-1 antitrypsin revealed that 37 diseased dogs had alpha-1 antitrypsin in the cytoplasm of their hepatocytes.

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Live endothelium provided a catalytic surface that at least doubled the rate of polymerization. Crystal phase of fibrous calcium phosphates prepared with sodium alginate. They enable to reduce the number of laboratory animals, that are necessary for research purposes. The neurotrophins, a family of growth factors best known for their positive effects on neuronal biology, have now been shown to mediate both positive and negative survival signals, by signalling through the Trk and p75 neurotrophin receptors, respectively.

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Magnetic resonance imaging of the cranium revealed periventricular lesions in the white matter of 3 of the 12 antibody-positive patients. The data and the model indicate that measures of contrast threshold using Gaussian-windowed stimuli (or any other nonflat contrast window) are determined not just by contrast response of the neurons activated by the stimulus but also by integration of that activation over a noisy, contrast-dependent extent of the stimulus in space and time. The quantities of acetaldehyde found in blood ranged from 2.04 micromol/ml (hamster) to 14.8 micromol/ml (pig). Two patients had known malignant melanoma and one a carcinoma of the breast. Some of the esterase activity that is normally assayed for resistance is apparently caused by the activity of the glutathione S-transferase.

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As new, more effective therapies become available, this will become more important. Life with an unwelcome guest - caring in a context of protracted bodily pain. Although abundant information is available on cellulase production, little of this work has examined oxygen transfer. We have isolated a cDNA clone encoding an antigenic polypeptide of Sarcocystis tenella by screening a cystozoite-derived cDNA library in lambda gt11 with antibodies from sheep infected experimentally with S.

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Ubiquitination of key cellular regulatory proteins marks them for efficient degradation via the proteasome pathway. The pronounced growth spurt of the brain at the about 10th day of life is probably due to the opening of the eyes. Synaptic burst-like activity is observed only for an intermediate range of excitatory and inhibitory connection strengths and external inputs. Sequential steps in axonal targeting are mediated by carbohydrate markers. Analysis of clone dynamics showed short-lived (days) progenitors (C1, M1, and Mix) yielding one or two cell types and long-lived (months) mucous cell progenitors (M0), columnar cell progenitors (C0), and pluripotential stem cells (S) capable of giving rise to all epithelial cell types.

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Incontinentia pigmenti: Block-Sultzburger, Block-Seimens disease. Honey dressing versus boiled potato peel in the treatment of burns: a prospective randomized study. The predictions of a cubic law are typically deviant from observation but somewhat less so than those of the Hubble law.

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New technologies for isolating differentially expressed genes from large arrayed cDNA libraries are reported. Rad51 is also specifically associated with developing synaptonemal complexes in meiotic cells, and BRCA1 and Rad51 were both detected on asynapsed (axial) elements of human synaptonemal complexes.

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This investigation sought to identify ways to overcome constraints related to logistics, supplies, and community participation. Sacral chordoma (SC) is a malignant bone tumor with high risk of local recurrence (LR) even after en bloc resection, generally in the first 10 years after resection. Acetaldehyde exerted a similar destabilizing effect on erythrocytes only in the case of oxidative hemolysis. Its purpose is to show the wide array of NMR techniques for 13C detection that are available for application in different systems to study aspects of brain metabolism, such as metabolic compartmentation and measurements of the tricarboxylic acid cycle rate in vivo.

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Developing new indices of diagnostic variability in an interlaboratory study. Sadness or depression: Making sense of low mood and the medicalization of everyday life. However, inference obtained from random-effects regression models is valid when the missing-at-random dropout process is present.

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Reporting randomized controlled trials in gastroenterology: the CONSORT statement. The presence of DA neurons within the hypothalamus offers the possibility of DA regulation of hypothalamic neurosecretory activity. Because the symptoms of premenstrual dysphoric disorder (PMDD) are limited to the luteal phase of the menstrual cycle, the potential benefit of luteal-phase dosing has been hypothesized. The anxiety and fear created by the notion that nearly all drugs cause congenital abnormalities may be more harmful than some proven human teratogenic drugs themselves. The case of a patient with this unusual combination of pathologic entities is presented.

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On the other hand, increased formation of histamine leading to an increase in gastric acid secretion is accompanied with gastroprotection and acceleration of gastric ulcer healing. Use of a stimulated echo sequence in the MRI study of the brain and spine This augmented death was mimicked by the nitric oxide releasing reagent 3-morpholinosydnonimine and was in part prevented by the nitric oxide synthase inhibitor NG-nitroarginine. A 68 year-old man was found outdoors after being exposed to five to eight hours of coldness. Osteosarcoma cells (BFO cell line) were successfully maintained in tissue culture for 3 years.

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Talc pleurodesis in recurrent malignant pleural effusion--a prospective follow-up study Intervention success was analyzed across 10 students (for a total of 213 goals). Advanced image analysis systems in cell, molecular and neurobiology applications.

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In fact, our experimental animal models revealed that tumors can induce lymphangiogenesis not only in primary sites, but in their draining lymph nodes (LNs), even before tumors get metastasized. Accessory pathways were identified in 32 patients (successfully ablated in 30) and dual atrioventricular nodal pathways in 18 patients (with successful ablation of the slow pathway in 17). The length comparison of the intergenic regions allowed for the identification of a number of Pellia species.

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The model predicts behavioral effects of neuronal ablations and genetic perturbations, as well as unexpected aspects of wild type behavior. Intravenous pyelography, ultrasound (other than transrectal) and bone scans were performed for staging more frequently in urban than rural cases. N-Acetylglucosamine 6-O-sulfotransferase-2 (GlcNAc6ST-2) catalyzes the sulfation of mucin-like glycoproteins, which function as ligands for a lymphocyte homing receptor, L-selectin, in the lymph node high endothelial venules (HEVs). Cyclophilin B (CyPB) is a cyclosporin A (CsA)-binding protein located within intracellular vesicles and released in biological fluids.

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Initial stability of a cementless acetabular cup design: experimental investigation on the effect of adding fins to the rim of the cup. We investigated the influence of a categorization task on the extraction and representation of perceptual features in humans and monkeys.

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In reference to Impact of Second Primary Tumors on Survival in Head and Neck Cancer: An Analysis of 2,063 Cases. The escape from detection of chronic polyarticular gout resulted in a needless dependence on NSAIDs, failure to correct the metabolic problem, and in some cases progression of joint destruction. One tradition uses primarily quantitative techniques to study clinic patients in order to improve service delivery and to assess the need for psychological counselling. Maoris were found to be at an unusually high risk of infection with Echinococcus granulosus, with incidence rates six times higher than those in non-Maoris.

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The P-protein was confined to bundle-sheath mitochondria throughout leaf development, and its content in individual mitochondria increased before the anatomical development of the bundle sheath. In conclusion, it is recalled that prognosis in fractures of the femoral neck is severe for generally gerontological reasons and the usefulness of biarticular endoprosthesis in the prevention of cotyloid wear and tear is underlined. The percutaneous endoscopic gastrostomy (PEG) cannot be performed for the patient after total gastrectomy. The present study was aimed at clarifying to what extent the hypermotility induced by the uncompetitive N-methyl-D-aspartate (NMDA) antagonist MK-801 depends on dopamine (DA) D-1 compared to D-2 receptor tone. Ageusia in carotid dissection is explained by the close anatomic relation of the internal carotid artery and the chorda tympani in the short petrous bone.

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In contrast, DTL inhibits the proliferative activity of HeLa cells grown on solid substrate and acts as inductor of differentiation, slowing cell growth, increasing the cell attachment and spreading. These data suggest that vascular relaxations induced by ginsenoside are mediated by release of endothelium-drived nitric oxide which enhances the accumulation of cGMP. We demonstrated that the free primary alcohol group is responsible for this rate acceleration because cycloSal-OAc-PCVMP, in which the hydroxyl group was blocked by acetylation, did not show the aforementioned acceleration. To investigate whether advanced glycation end products (AGEs) participate in the development of coronary artery disease (CAD) in nondiabetic and diabetic subjects.

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Photodynamic therapy is a new treatment modality using light to activate a photosensitiser that preferentially localises in tumour cells. Adjuvant pain treatment in cancer: a case for psychopharmacology. In a previous report, we demonstrated that the presence of RAS is independently associated with mortality in a group of patients undergoing coronary angiography.

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A complex sample consisting of a cyclic gel polymer containing fibril nanostructures was also tested with FMM measurements. Restriction fragment length polymorphism analysis and assignment of the metalloproteinases stromelysin and collagenase to the long arm of chromosome 11.

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Collecting all the pressure histories at the field points, source-observer relations can be constructed in a matrix-vector form for each frequency. The authors describe the preliminary result of their experience in patients with IMCVDs who have been treated with etanercept, a tumor necrosis factor alpha receptor blocker, recently approved by the United States Food and Drug Administration for the treatment of rheumatoid arthritis. In case 1, the utricular macula and the lateral and anterior cristae were observed, with all sensory epithelia showing fairly normal findings. Results also indicate that the effects of chromatic contrast may be mediated by local contrast mechanisms, but that the relationship between threshold and luminance contrast is not mediated entirely by these local contrast mechanisms.

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Intertrochanteric osteotomy for posttraumatic arthritis after acetabular fractures. As an increasing number of large prospective studies show a high accuracy of the sentinel node for the staging of the axilla in women with invasive breast cancer, there is no need to test the value of this new technique in a randomised trial. The informal gathering in the evening had offered a fascinating original report such as an old documentary film about Imu, a Japanese culture bound syndrome. Our analysis is based on the lattice-gas model describing surface restructuring in terms of the statistical theory of first-order phase transitions.

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MR in both patients later demonstrated progressive widening of the sulci, ventricles, and cisterna magna, and loss of brain volume. Evidence that the inflammatory process induces bio-chemical changes at a neuronal level has also been obtained. The change in electrical activation from resynchronization, which has no positive inotropic effect as such, is translated into mechanical improvement with a more coordinated left ventricular contraction.

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Disorders of the reproductive function and the blood prolactin level in men with chronic liver diseases How can second-line therapy for metastatic renal cell carcinoma help to define an overall management strategy? A detailed mapping of somatosensory thalamus was performed in each animal, and VMpo was identified by recordings from clusters of thermoreceptive-specific and nociceptive-specific (NS) neurons. There is a need to clarify the contribution of the shoot to drought resistance from the level of the biochemistry of photosynthesis through stomatal behaviour and leaf anatomy to canopy architecture. To retrospectively analyze the long-term results of prophylactic central lymph node dissection in cN0 papillary thyroid carcinoma (PTC), and investigate the treatment method of the cervical lymph nodes for cN0 PTC.

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We have previously reported a tetraketide origin for theobroxide and its related compound. Five days after preimmunization, rats fed fish oil had more rabbit IgG remaining in their serum and had mounted less of an antibody response to the rabbit IgG. We studied the kinetics of liver aldehyde dehydrogenase in rats with cold injury. Surprisingly, for this effect of TLR3 signaling, the adaptor proteins, TRIF and MyD88, were not required.

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The frequency and variety of informal care reported in this study strongly argues for profession-wide discussion about ethical and guideline considerations for such behaviour. The clinical findings of 10 children with acquired toxoplasmosis were tabulated. Both the N- and C-terminal regions of RelA were responsible for the PP2A binding. Two patients had an arterial fistula--one iliaco-iliac, one brachio-brachial. Evidence for predisposition in humans to infection with Ascaris, hookworm, Enterobius and Trichuris in a South Indian fishing community.

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Apoptosis in PC3 cells was analyzed by DNA fragmentation, sub-G(1) DNA content with flow cytometry, and terminal deoxynucleotide transferase-mediated dUTP nick end-labeling (TUNEL) method. They are potentially interesting for the assessment of various cardiac functions. Using voxel-based morphometry, we related differences in performance in these path integration tasks to variation in brain morphology in 26 healthy young adults. In addition, significant improvements in survival and auditory function were seen in AAV-treated MPS VII mice when compared with untreated mutant siblings.

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Antagonism produced by hypertonic nutrient solutions on the depressive effect of carbofuran on isolated guinea pig atria. Cochlear Implant are considered an efficient technique in the treatment of profound neurosensorial deafness, in Pre and Postlinguistic patients.

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To test this hypothesis, we used site-directed mutagenesis to replace three conserved negatively charged residues in the N-type calcium channel alpha1B subunit (Glu-1321, Asp-1323, and Glu-1332) with positively charged amino acids (lysine and arginine) and studied their effect on ion selectivity using whole cell and single channel patch clamp recordings. Professional training for surgeons and barbers in Mallorca in the 14th and 15th centuries The iodine status of the adolescent girls was determined through urinary iodine levels.

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Although local anesthetics (LAs) are widely used in clinical practice, it remains unclear whether LAs such as lidocaine, ropivacaine, and bupivacaine affect neutrophil mitochondrial functions. Two Dirofilaria ursi, six Trichodectes pinguis and numerous Haemaphysalis megaspinosa were obtained from an Asiatic black bear (Ursus thibetanus) shot in Kyushu, Japan. The biopsy analysis showed fragments of the incisive artery and nerve, which are responsible for the anterior upper-tooth pulp, the periodontium vascularization and the innervation. Three proteins, with monomeric molecular masses of 43, 35 and 31 kDa, were enriched in total or sedimentable fractions of autophagosomes relative to the corresponding fractions of postnuclear supernatant, suggesting an association with the autophagosomal delimiting membrane. Among patients who receive enteral nutrition through a gastric fistula, some are concomitantly administered viscosity modifiers to avoid aspiration pneumonitis caused by gastroesophageal reflux.

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For glass wool of mass density 14 kg/m3 at the frequency 1,000 Hz, the attenuation constant for propagation perpendicular to the glass wool sheets was 75 dB/m, and for propagation parallel with the sheets 57 dB/m. The objective of our study was to compare the standard protocol of anticoagulation to the Hepcon/HMS. Results The prevalence of occupational and leisure physical activity and compliance with recommendations were lower in women.

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One hundred and fifty human vaginal samples containing a diversity of pathogens or nonpathogens (Gardnerella vaginalis, Streptococcus sp., Staphylococcus sp., Candida albicans. Undercarboxylated osteocalcin (ucOC) level should be considered a marker of the risk of hip fracture. A recognized national standard for dosing that can be implemented in computerized physician order entry systems is needed so that evidence-based pediatric dosages can be calculated.