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We describe five patients with a suspected defect in the beta-oxidation of fatty acids characterized by a massive excretion of 3-hydroxydicarboxylic acids in the urine and accumulation of 3-hydroxy fatty acids in serum during acute illness. A) The Mannich-reaction of ketone 2 yields the bases 4-HCl and 5-HCl. Increased acceptance of the International Normalized Ratio (INR) as a monitoring parameter of oral anticoagulation therapy in Germany.

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The derived sequence is composed of 532 amino acids and represents a protein having a molecular weight of 58,952. The SH-3BP-2 mutation may participate in the differentiation and maturation of osteoclast-like cells in the lesion of cherubism.

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The smaller particles of size of 3-5 nm showed frequent fluctuation, while the nanoparticles of more than 10 nm in size showed relatively slower fluctuation. An osteochondral plug from the non-weight-bearing articular surface of the knee is transferred and press-fit to resurface a focal metacarpal head defect. No interocular differences were noted with respect to the amplitudes of responses to the light bars and gratings. Economic models based on measures of resource utilization derived from RCTs have provided FN risk threshold estimates for the cost-saving use of prophylactic CSF.

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In extending this work to rats, we used three different ER antibodies to determine if this decrease in ER-IR is likely to be due to down-regulation of the receptor by estradiol or a decrease in the ability of some antibodies to bind to their particular epitopes on the receptor. Therefore, early removal of white cells should prevent reactions. As a result, it is possible to use in-situ gamma-ray spectrometry to obtain the total 137Cs activity per unit area also for sites where the vertical distribution of this radionuclide in the soil is no longer exponential.

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The study population consisted of 178 adult patients who had undergone groin hernia repair surgery in the previous year. Results of conservative and operative treatment of distal intra-articular tibial fractures

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Involvement of family and community medicine professionals in community projects. Physiological reactions during acute adaptation to reduced gravity. Nitric oxide (NO) has antithrombotic properties by regulating platelet function, whereas direct effects on plasmatic coagulation are rarely described. The clinical picture varies markedly, unmistakable symptoms are followed by a period of impaired health in a number of cases.

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Recombinant or native proteins representing the sequence of PfMSP1 from the Wellcome strain of P. For a pre- and postoperative comparison we divided the patients in two groups. mRNA levels for N-cadherin and alpha-catenin were significantly higher in glioblastomas than in low-grade astrocytomas or normal brain, while the levels of intact N-cadherin protein were similar in glioblastomas, low-grade astrocytomas and brain.

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A total of 1,295 individuals from 300 families were studied in a community-based cross-sectional study in Chennai, India. The schedule consisted of one choice trial between the intake of normal food and drug-admixed food followed by two consecutive forced trials, in which the rats were forced to take the drug-admixed food only. Effects of step aerobics and aerobic dancing on serum lipids and lipoproteins. Molecular analysis of the Rhodobacter capsulatus chaperonin (groESL) operon: purification and characterization of Cpn60. Using the low-frequency Raman spectroscopy to analyze the crystallization of amorphous indomethacin.

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Noise-amplitude dependence of the invariant density for noisy, fully chaotic one-dimensional maps. Cerebral palsy had been misdiagnosed in both of these patients at another hospital.

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This paper describes the evolution of efforts to prevent cardiovascular disease, from individual health education approaches to broader community education efforts and, finally, to comprehensive and integrated programs addressing environmental, policy, and individual behavior change. Lemon extract was the active compound that received a better score, thus suggesting using 2,000 ppm of citrus extract in the last step.

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Analysis of the results of a prevention program in France (1989-1991). We conclude that this network is a characteristic structure of spindle cell thymomas and is related to the invasiveness of the tumor. Binding of Ru(II) polyazaaromatic complexes to DNA: A 23Na NMR spin-lattice relaxation study.

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Primary cardiac tumors causing sudden death: a review of the literature. Moreover, the level of expression correlated with the extent of mucosal damage in gluten-sensitive individuals. Prevalence of psychiatric diagnoses, physical, cognitive, and emotional symptoms, and course of PTSD across time. A meta-analysis of three, large-scale, prospective studies in men, and the first study to examine the correlation of LDL particle size distribution and vascular changes measured by B-mode ultrasound, add to growing evidence that small, dense LDL is atherogenic. The series included 22 cases of intraductal hyperplasia without atypia, 6 cases of intraductal hyperplasia with atypia, and 23 cases of pure intraductal carcinoma.

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Acral pseudolymphomatous angiokeratoma of children: a pseudolymphoma rather than an angiokeratoma. At present the most common combination of antidotes against soman, consisting of obidoxime and atropine, as well as a prospective combination containing oxime HI-6 and atropine should be supplemented with diazepam not only to prevent centrally induced seizures and tonic-clonic convulsions but also to increase the ability of such antidotal therapy to eliminate acute lethal toxicity of soman.

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The findings of these initial studies are now being evaluated in large multi-institution chemoprevention trials. Our approach made use of several key experimental attributes of the developing mouse lens, namely its strong dependence on pRb in maintenance of the postmitotic state, the down-regulation of cyclins D and E and up-regulation of the p57(KIP2) inhibitor in the postmitotic lens fiber cell compartment, and the ability to target transgene expression to this compartment.

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Phase II trial of infusional fluorouracil, irinotecan, and bevacizumab for metastatic colorectal cancer: efficacy and circulating angiogenic biomarkers associated with therapeutic resistance. Lack of M-PFK enzyme activity was caused by a nonsense mutation in the penultimate exon of the M-PFK gene, leading to rapid degradation of a truncated (40 amino acids) and therefore unstable M-PFK protein. The prevalences of helminth parasites found on red foxes collected in two different habitats of the Ebro Valley, in north-eastern Spain were compared.

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We also found an increased collagen content and decreased ER receptor protein level in aged, smoke-exposed female mice. Those in a second modification treatment received the information and practice but were not exposed to the model. Her symptoms required multiple procedures and hospital admissions for what appeared to be anatomical problems. Metabolism of red blood cells and estrogen hormones in the course of gestation complicated by Rh isoimmunization

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In our opinion, the same basic principles used for treatment of cancers of the orthotopic breast should be applied in ectopic breast carcinoma. Possible implications of these results with regard to neuroprotective role of FGF are discussed. parahaemolyticus elicited at least one Hsp 60 (GroEL)-like protein with apparent molecular weight of about 58,000 (58 kDa) when submitted to a heat shift from 30 to 42 degrees C. The aim of this study was to assess the effects of follow-up counselling on the duration and severity of nausea and vomiting in pregnant women. In addition, in an 80-week relapse prevention trial, sertraline was found to reduce severity and frequency of panic attacks, baseline anxiety and to confer protection from relapse for up to 36 weeks following withdrawal from medication Data on sertraline as an alternative to tricyclic antidepressants and paroxetine in terms of tolerability is presented here.

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Long-term course of surgically induced astigmatism after a 5.0 mm sclerocorneal valve incision. Diagnosis of either healed or relapsed DU was on an endoscopic basis. In a second study, 15 pigs underwent off-pump bypass surgery (LIMA to LAD grafting) and the catheter was used to provide myocardial perfusion and prevent bleeding at the site of the coronary anastomosis. The efficacy of preoperative localization was evaluated in terms of procedure time, VATS success rate and associated complications of localization.

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In this study, using this immunoblot assay, we investigated sera obtained from 26 patients who showed atypical clinical features. In a second step the optimized technique was implemented on 10 healthy Beagle dogs, included in the study. By contrast, an increase in the capacity to store blood volume was found in the venous anastomoses.(ABSTRACT TRUNCATED AT 250 WORDS) Immunoglobulins with hapten-binding activity: structure-function correlations and genetic implications. In the present study, we reported studies on the effect of conditioned medium obtained from cultures of rabbit craniofacial chondrocytes on GAG and DNA syntheses in the same chondrocyte cultures.

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Whereas, SK derivative, devoid of its first 13 N-terminal aa residues, could not do so. The experiment, where 12 healthy subjects participated, involved one motor sequence with a single limb and three kinds of motor sequences with two or three limbs. We propose that TGF beta has a bifunctional role in carcinogenesis, retarding carcinoma development but enhancing progression once neoplastic transformation has occurred and the growth inhibitory response to TGF beta has been lost. While there is plenty of evidence for deceptive communication in humans the possibility of deception is not yet incorporated into models of indirect reciprocity. Female tammar wallabies were treated with the dopamine agonist bromocriptine at the end of pregnancy to suppress the peripartum pulse of plasma prolactin.

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SPOP (Speckle-type POZ Protein) was one of the most frequently mutated genes in primary prostate cancer, suggesting SPOP is a potential driver of prostate cancer development and progression. thermocellum is hindered due to the incomplete description of its metabolic repertoire and regulation within a predictive metabolic model. AGEs have been implicated previously in the pathogenesis of the end-organ complications of diabetes and ageing, including cataract, atherosclerosis and renal insufficiency. Zinc is an essential ion that is crucial for maintenance of normal physiology, and zinc deficiency has many manifestations ranging from delayed wound healing to immune dysfunction and impairment of multiple sensory systems. Biodegradable materials used for drug delivery are of great demand due to their ability to degrade into low molecular weight species and further excrete from the body by metabolism.

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No decision has yet been made as to future changes to the funding policy of WA public hospitals. The hypothesis that endothelial dysfunction is a systemic process is explored, and new noninvasive methods of assessing endothelial function are discussed. Critical analysis about solutions and models of solar shades in non-residential buildings from tropical regions. Mechanisms of action and targets of nitric oxide in the oculomotor system. This study aimed to explore the prevalence of carnitine deficiency in pediatric cancer patients and its relationship with fatigue and other potential contributing factors.

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This was a retrospective analysis of ultrasound volume data obtained in 110 women after undergoing the Monarc suburethral sling procedure. In addition, the time constant of vertical OKAN with slow phase up was larger than on the ground. Microbial intestinal disturbances in children with frequent acute complicated pneumonia

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The built environment and health: introducing individual space-time behavior. While VanA phenotypes were efficiently detected, problems were experienced in detecting VanB and VanC phenotypes. Some Preventive Measures to Diminish the Number of Abortions and Still-Births. Simultaneous determination of evodiamine and rutecarpine in rabbit plasma by LC-ESI-MS and its application to pharmacokinetics. A retrospective review was made of 45 consecutive patients who underwent a pars plana vitrectomy procedure for repair of ocular trauma.

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The influence of surface area on the in vitro cytotoxicity of a range of dental materials. Tissue reaction of bioabsorbable ultra high strength poly (L-lactide) rod. Malignant spiradenomas (spiradenocarcinomas) are exceedingly rare tumours of cutaneous adnexal origin, consisting of two components: benign--the pre-existent adenoma, and malignant--developing from the former part. Considerations were made regarding the intriguing expression of CK 14, the heterogeneous expression of CKs in the modified myoepithelial cells and the immunoprofile of the polymorphous low-grade adenocarcinoma.

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Effects of sulphonylureas on spontaneous motility and induced contractions in rat isolated uterus. Beta-thalassaemia in Campania: DNA polymorphism analysis in beta A and beta thal chromosomes and its usefulness in prenatal diagnosis. Findings indicated that the scientific method was used with varied levels of sophistication.

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Full sensory and motor evaluations were performed and physical contraindications to stimulation were catalogued. We conclude that cell death has a major role in the destruction of tail structures and the concurrent loss of the human tail. The modified Total Neuropathy Scale, the NeuroCom SMART Balance Master system computerized dynamic posturography (CDP) that includes the Sensory Organization Test (SOT) and the limits of stability (LOS), and the Activities-specific Balance and Confidence (ABC) scale.

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This isoform arises by alternative splicing of the first exon of the FHF-2 gene and is predicted to encode a polypeptide with a distinct amino-terminus. Protection by albumin against ischaemia- and hypoxia-induced hepatic injury. Brain tumors in patients with medically intractable epilepsy are almost always benign and located in the temporal lobe. Human mtDNA and Y-chromosome variation is correlated with matrilocal versus patrilocal residence.

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This study was conducted in order to determine the effects of high levels of right- and left-handedness on epicondyle of the humerus. MRI including diffusion-weighted sequences (DW-MRI) has demonstrated its high sensitivity for acute supratentorial ischemic lesions. RAD51 mRNA was significantly downregulated in individuals with CMM resulting from the degradation of the mutated mRNA by nonsense-mediated decay.

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These were adequately covered by two of the scales, the Brief Psychiatric Rating Scale (BPRS) and the Psychotic Inpatient Profile (PIP), which together took 7 1/2 minutes to complete. The few studies performed with the different cell types available in the nervous system of fish allow us to hypothesize few functional relationships among those cells. In rotation experiments, 5-carboxyamidotryptamine and methysergide had effective agonist activity in dose ranges similar to that of serotonin (1 to 100 microM). The Smad proteins and the c-Jun N-terminal kinase (JNK) have been shown to be involved in TGF-beta signaling pathways. Single axons of tectospinal (TS) and reticulospinal (RS) neurons were stained with intraaxonal injection of HRP after electrophysiological identification, and their axonal trajectory was reconstructed at C1-C3 of the cat.

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On-line sample preconcentration is an essential tool in the development of microfluidic-based separation platforms. After operation, ambulation and rearing of aged rats increased more slowly as compared to that of young animals. We purified and fully sequenced 30 novel adenoviruses from apes and 3 novel adenoviruses from macaques. This report describes the method of removal of a pedicle screw that had been misplaced through the thecal sac and the cauda equina instead of its proper location within the pedicle.

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Saturated fatty aldehydes have not been reported previously as body surface components of hard ticks. In a study designed to examine the short-term immunological effects of thought suppression, participants wrote about either emotional or nonemotional topics with or without thought suppression. Samples were analyzed on a FACScan flow cytometer using the software MODFIT. The patient underwent testing for spinal cord stimulation and spinal drug delivery.

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On the basis of the clinical assessment and the additional studies the necessity for a coronary angiography can be decided on in most instances. Socioeconomic analysis of nursing service--socioeconomic changes surrounding nursing The size of the mitral orifice was determined according to oximetry blood analyses and hemodynamic parameters.

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An improved bromide assay for the estimation of extracellular water volume by capillary gas chromatography. Acute obstruction of the renal collecting system: the intrarenal resistive index is a useful yet time-dependent parameter for diagnosis. We derive a formally simple approximate analytical solution to the Poisson-Boltzmann equation for the spherical system via a geometric mapping. Recent improvements in microsurgical techniques on lymphatic vessels facilitated the treatment of lymphoedema.

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The Internet offers many possibilities to increase access to evidence-based psychological treatments of depression. However, both the roles of these proteins in the plant physiology, and the mechanisms involved in the regulation of their expression are largely unknown. Multiple independent transpositions of mitochondrial DNA control region sequences to the nucleus. Measurement of acidic aerosol species in eastern Europe: implications for air pollution epidemiology.

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Single-stage combined anterior-posterior stabilization and fusion for superior and distant cervical spine fractures This reaction is catalyzed by methionine adenosyltransferase (MAT). Analysis of forward scatter of the granulosa cells, which is correlated to cell size, shows a wide size range throughout the whole population rather than two distinct populations as previously suggested.

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The fibrinolytic activity of plasma was determined by measuring the plasmin activity of the euglobulin fraction and was increased to two-folds of the control at a dose of 0.5 g/kg/day and five times with 1 g/kg/day after 4-day administration. From a toxicological standpoint, posttranscriptional regulation of these genes aids in the sequestration, control, and hence prevention of cytotoxic effects from free-floating nontransferrin-bound iron. Isoforms of cytoskeletal actin and actin-associated proteins (non-muscle myosins, cytoskeletal tropomyosins, and cytoskeletal alpha-actinins) have been detected in a number of regions of striated muscle: the sub-sarcolemmal costamere, the Z-disc and the T-tubule/sarcoplasmic reticulum membranes. A single-element spherically focused transducer of 5 cm diameter, focusing at 10 cm and operating at 1 MHz was used.

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Antibiotic-impregnated heart valve sewing rings for treatment and prophylaxis of bacterial endocarditis. The experiment was discontinued on day 21, and total oxidant system (TOS), total antioxidant system (TAS), oxidative stress index (OSI), and malondialdehyde (MDA) were measured in order to evaluate oxidative damage to the heart tissue.

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A variety of lectins were tested in vitro for inhibitory action against the activities of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase and the N-glycohydrolases (alpha-glucosidase, beta-glucosidase and beta-glucuronidase). These results indicate that telomerase activation may be a critical step in the pathogenesis of intracranial tumors. Application to Aspergillus niger and Phanerochaete chrysosporium. Methanosarcina-like microorganisms were predominant in the PVC and the polyurethane foam matrices. Recent advances in use of silver nanoparticles as antimalarial agents.

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We decreased the false-positive rate of 5-aminolevulinic acid induced fluorescence endoscopy by incorporating protoporphyrin IX fluorescence quantification into the standard cystoscopy procedure. Thirty-seven male cocaine dependent (CD) and 52 normal control subjects between ages 19 and 47 were evaluated with MRI. We assessed this at ages 1-2 yrs and 6-8 yrs in 3,062 Dutch children from a pooled data set of three birth cohorts: PIAMA (Prevention and Incidence Asthma and Mite Allergy), PREVASC (Prevention of Asthma in Children) and KOALA (Child, parents and health: lifestyle and genetic constitution). Growth hormone and seawater adaptation in coho salmon, Oncorhynchus kisutch. Residents were recruited from 9 randomly selected urban clusters and 4 randomly selected rural clusters in Victoria, Australia.