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Molecular genetic truncation analysis of filament assembly and phosphorylation domains of Dictyostelium myosin heavy chain. In patients with PAOD stage II considerable effects on functional capacity and important dimensions of quality of life can be achieved by a short exercise and education program. Blonanserin Augmentation for Treatment-Resistant Somatic Symptom Disorder: A Case Series. In this study, there appeared to be a decrease in FDG uptake in prostate cancer after endocrine therapy not only in primary prostate cancer lesions but also at metastatic sites, suggesting that the glucose utilization by tumours was suppressed by androgen ablation. This study finds further evidence for a contribution of the ADH2 polymorphism to skin reactions after either local or systemic ethanol exposure in Asian people.

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CD8-positive lymphomas are rare, unclassifiable tumours with variable prognosis. Microsatellite markers were developed in Fosterella christophii (Bromeliaceae) to investigate the genetic diversity and population structure within the F. Adhesion molecules, therefore, are modulator molecules which alter the biological behavior of normal or leukemic hematopoietic cells, primarily in terms of migration and localization properties, although they also participate in many other cell functions such as cytotoxicity, antigen presentation and binding of viruses or cancer cells. High-frequency ventilation stabilized the infant, permitting distal occlusion of the esophagus with a Silastic band. In the present report of 160 consecutive renal transplant patients, we used a diagnostic assay for CMV antigenemia (detection of CMV antigen in peripheral blood leukocytes) and treated with ganciclovir only those patients who had a positive test.

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Magnetic resonance spectroscopy (MRS) remains the technique of choice for observing tumour metabolism non-invasively. In our experiments we used HPC in free (micellar) or liposomal form in different primer/trigger combinations with lipopolysaccharide (LPS).

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Expertise is required for the preparation of diagnostic antigens and in the interpretation of tests. Central performance drop in texture segmentation: the role of spatial and temporal factors. To examine the mechanism of the effect of calcitriol on EGFR expression, confluent cultures of UMR 106-01 cells were exposed to calcitriol and levels of EGFR mRNA were determined by reverse transcription-polymerase chain reaction (RT-PCR). Regulation in work and decision-making in the activity of public prosecutors in Santa Catarina, Brazil. discoideum cells has been the suggestion of a developmental path the cells follow (Lauzeral and coworkers).

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Systemic and regional hemodynamics in low, normal and high cardiac output borderline hypertension. In addition, the NT-induced catalepsy was dose-dependently reduced by antihistamines, such as diphenhydramine (0.8-10 mg/kg, IP) and tripelennamine (0.4-5.0 mg/kg, IP) and was potentiated after treatment with histidine (250, 500 mg/kg, IP), a precursor of brain histamine. However, only men were included in the present study, and the present findings cannot be extrapolated to women. Mechanisms underlying the relationship between divergent selection for immune responsiveness and body weight are discussed.

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Effect of oral cadmium exposure during pregnancy on maternal and fetal zinc metabolism in the rat. The pathogenesis of exanthema in spotted fever and typhoid diseases

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Theoretical and practical considerations concerning the use of eye movement data are also discussed. Thirteen years later she presented with 3 months of profuse watery diarrhea, hypokalemia, hypercalcemia, hyperchloremic metabolic acidosis, and a normal anion gap. Most previous studies have focused on demineralization and bonding to normal dentin, although many bonding procedures involve altered dentin substrates, such as those modified by caries.

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Phylogenetic analyses using probabilistic methods recovered three major lineages, whose divergence coincided in time with sea level and ocean current changes as well as temperature fluctuations during the Messinian salinity crisis and the Plio-Pleistocene transition. Multiple restriction site polymorphism at the human somatostatin locus: a population study in Italy. Similarly, neither treatment caused any significant changes in total median eminence or posterior pituitary AVP and OT contents relative to controls, although dexamethasone-treated rats had a significantly lower posterior pituitary OT content than adrenalectomized rats. Compound Muniziqi granule (MNZQ), a traditional Uighur medicinal preparation, comprises 13 species of medicinal plants.

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However, for patients who were intoxicated at the time of injury, there were uniformly low S100B levels across all clinical groups. We determined field rates of growth, reproduction, and senescence in four cohorts of B.

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Thirty-two extracted human teeth were perforated in the middle third of the root and embedded in alginate. Interactions of alcohol with drugs are numerous, varied sometimes with an inverse effect according to acute or chronic consumption. The Harmonic scalpel (HS) and LigaSure (LS) are the most commonly used devices in laparoscopic surgery. The relationship between essential fatty acid (EFA) deficiency and disturbance of prostaglandin (PG) biosynthesis was studied in children after radical operation for extrahepatic biliary atresia (EBA). Purified rat-liver acetyl-CoA carboxylase was found to be phosphorylated and activated by protein kinase C, thus providing a possible mechanism for the metabolic action of PMA in intact hepatocytes.

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(3) Dimensional analyses showed that while subjects with low CSF 5-HIAA exhibited high rates of aggression, high CSF testosterone further augmented rates and intensity of aggression in subjects with low CSF 5-HIAA. Antioxidant changes in juvenile visceral steatosis (JVS) mice, a model of heart hypertrophy due to disorder of fatty-acid oxidation, were examined at 4 weeks (developing hypertrophy stage) and 8 weeks of age (established hypertrophy stage). The importance of capillary permeability in the physiopathology of intestinal obstruction Effect of peripheral vasodilators on thrombocyte aggregation in chronic circulatory insufficiency Furthermore, using the Tunel method, no stained nuclei were observed in the two groups of animals.

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After roughly one decade of use in clinical practice it is considered valuable for breast cancer therapy monitoring and, in the follow up, for early detection of metastatic disease. Tibial agenesis: a new rationale in management of type II--report of three cases with long-term follow-up. Infantile experience and mature aggressive behavior of mice: some maternal influences. The basic improvement of the item is the use of highly transparent glass fibres which provide excellent transmission at 200 nm and the use of a special fibre arrangement for plate illumination and detection. Costs may be reduced due to decreased monitoring and administration.

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The two flagellins have deletions at Ala-204 to Lys-292 and Thr-183 to Lys-279, respectively. Progressive frontal fibrosing alopecia is a clinically distinct variant of lichen planopilaris that affects in particular elderly women and frequently involves the eyebrows. The cellular microenvironment plays a critical role in shaping and directing the process of communication between the cells. A genome-wide screen in Saccharomyces cerevisiae reveals a critical role for the mitochondria in the toxicity of a trichothecene mycotoxin.

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In 27 LARC patients receiving neoadjuvant chemotherapy (NACT) before chemoradiotherapy (CRT), T2W- and DW MRI were obtained before and after NACT. Indeed, homozygous deletion of Xrcc1 does not impair A-EJ of I-SceI-induced DSBs in XRCC4-deficient pro-B-cell lines.

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Neonates presenting with temperature symptoms: role in the diagnosis of early onset sepsis. We propose that these accumulations perturb the process of myelination and impair the viability of oligodendrocytes. Southern blot analysis was used to compare sheep and goat restriction-endonuclease maps of the DNA region containing the alpha-globin genes. Grass specific IgE reactivity of the mix grass modified extract (allergoid) was diminished in comparison with the mix grass native extract.

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In eosinophilic pulmonary inflammation, its therapeutic mechanism has not been established. The complex health issues facing urban areas require effective public policy responses. At risk in two worlds: injury mortality among indigenous people in the US and Australia, 1990-92. Two weeks after irradiation, the nerve velocity of the common peroneal nerve and the toe expanding test were investigated. The recombinant protein was expressed in Escherichia coli system, in insoluble form, recovered by urea solubilization and further refolded by decreasing the denaturing agent concentration during the purification procedure.

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The present study uses the novel technique of Fourier transform infrared microspectroscopy equipped with differential scanning calorimetry (FT-IR/DSC microscopic system) to accelerate and determine simultaneously the thermal-dependent impurity formation of solid-state APM. An approach to reduce the number of skin samples in testing the transdermal permeation of drugs.

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For unequal effects, disruptive selection can be observed for weaker competition and in the absence of a stable polymorphism. Hyperthermia is a common secondary insult in traumatic brain injury (TBI). Urea was a better chaotropic solvent than guanidine HCl, and physiological salt concentrations and pH were needed for optimal recovery of enzymatic activity.

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Treatment results and the work capacity status of patients with fracture-dislocations of the talocrural joint We compared these outcomes in patients with MNFS or nonmodular femoral stem (NFS) THA. Occupational health nurses contribute a critical component to the respiratory protection program. Energy substrates and the completion of spontaneous meiotic maturation. Although reports of successful pregnancy after liver transplantation continue to increase, these pregnancies are considered of high-risk because they are associated with increase maternofetal morbidity.

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This finding validates the use of transition state theory underlying all phi-value analyses. Acute renal failure after radiofrequency liver ablation of metastatic carcinoid tumor. The transcription factor peroxisome proliferator-activated receptor (PPAR)-gamma plays an important role in controlling cell differentiation.

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Head-mounted field-effect transistors are frequently used for electrophysiological recording of brain potentials in freely moving animals. Bone mechanical properties after exercise training in young and old rats. Acute ischemia followed by hemorrhagic gastric necrosis after injection sclerotherapy for ulcer. The study showed that all three methods to determine occupational exposure can yield representative time-weighted exposure patterns.

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In this paper, a design and a prototype for a decision-support system in the field of urinary tract infections using techniques and methods developed in the GALEN projects is presented. Improving the performance of interferometric imaging through the use of disturbance feedforward. Several clinical trials investigating myopic excimer laser photorefractive keratectomy (PRK) report an initial change in refraction from myopia to hyperopia, followed by a gradual regression toward emmetropia and occasionally to recurrent myopia. Lumican (LUM) is one of the major extracellular matrix components of the sclera. Examples of focal hair matrix differentiation in a follicular cyst, a cutaneous mixed tumor, and an adnexal carcinoma are presented.

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Nitric oxide induced cervical ripening in the human: Involvement of cyclic guanosine monophosphate, prostaglandin F(2 alpha), and prostaglandin E(2). Advances in the design of special cryosurgical apparatus in China. When the levels of 16 alpha OH-P5 and 16 alpha OH-P4 were taken into account, 14 of 17 cases of IUGR were discriminated from normal subjects.

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Plasma intact parathyroid hormone, serum calcium, and phosphorus concentrations were measured for PD evaluation. Four homecare nurses assisted in the distribution and collection of questionnaires. Evaluation of a Live Attenuated Human Metapneumovirus Vaccine in Adults and Children. and Rhodococcus erythropolis were minor components of the hydrocarbon-oxidizing bacteriocenosis under the conditions of sulfate reduction. Using chromosomal lacIQ1 to control expression of genes on high-copy-number plasmids in Escherichia coli.

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After solid-phase extraction, the reconstituted samples were divided into aliquots for analysis by HPLC and GC-MS. Monocyte chemoattractant protein 1 is a prognostic marker in ANCA-associated small vessel vasculitis. Asymmetry of interhemispheric responses evoked in the prefrontal cortex of the rat. Blood compatibility of these surfaces was greatly improved with draw ratio in terms of a change in cytoplasmic calcium levels in platelets contacting these surfaces.

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Prevalence of disability in three birth cohorts at old age over time spans of 10 and 20 years. The main purpose of this study has been to research the prevalence of AP in patients with diabetes mellitus (DM) and to underline the importance of hypertriglyceridemia (HTG) as a risk factor in triggering AP. Strong electrostatic coupling among catalytic residues His108, Asp144, and substrate GAR was observed, which is extremely sensitive to the initial protonation and imidazole ring flip state of His108 and small structural changes.

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The dry-weight and volume of the neurohypophysis increased significantly with age but the quantity of vasopressin in the gland remained constant. Detection of species A, B, and D EVs infecting wild chimpanzees demonstrates their potential widespread circulation in primates.

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Vehicle-treated rats became progressively more resistant to afterdischarges and convulsions with successive stimulations but L-No-Arg-treated rats failed to do so. Mobility upon gel-filtration chromatography gives much higher apparent molecular masses for both species, whereas the mobility of FliI is normal. Three patients demonstrated generalized lung involvement by both radiologic techniques. In contrast, overexpression of a well-known cell death-inhibiting protein such as Bcl-2 or Bcl-XL did not attenuate 6-OHDA-induced cell death.

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Direct complementation of Chlamydomonas mutants with amplified YAC DNA. We present experimental measurements, obtained by a quasielastic neutron scattering experiment, of the self-diffusion coefficient of water confined in the dense structure of lecithin-based gels. However, there was a slight decrease in the network after bilateral single-level resection or unilateral multisegmental resection. Currently, the cover of the femoral head was mainly assessed using conventional plain films after Chiari pelvic osteotomy in most studies.

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The design of potential antidiabetic drugs: experimental investigation of a number of beta-D-glucose analogue inhibitors of glycogen phosphorylase. The conjunctival melanoma was completely resected microsurgically in one piece without disrupting the tumor. Damage to some contractile and cytoskeleton proteins of the sarcomere in rat neonatal cardiomyocytes after exposure to pavetamine. The work was motivated by a recent draft from the American Food and Drug Administration (FDA) on the treatment of high blood pressure (FDA, 1990, Draft of the Proposed Guidelines for the Clinical Evaluation of Antihypertensive Drugs). The sec-independent twin-arginine translocation system can transport both tightly folded and malfolded proteins across the thylakoid membrane.

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These results indicate that medullary TRH plays a role in the vagally mediated adaptive gastric protection induced by mild acid. This achieves stability which is likely to improve results and reduce complications. Luc gene expression driven by baculovirus regulatory elements was detected by enzyme and photometric assays. Our purpose was to explore the importance persons place on various features of skin lesions when looking for early signs of melanoma. While tissue stiffness was greater when a scalpel was used compared to electrocuting to incise the midline abdominal fascia in rats, there was no difference in the bursting force required to disrupt the wound.

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Although absolute RNA and DNA contents increased with age, their relative concentrations decreased. To run a phase II clinical trial of cytarabine in men with docetaxel-refractory, castration-resistant prostate cancer (CRPC), based on evidence that cytarabine might be effective in men with abnormalities of ERG oncogenes.

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Effect of hydrophobization of basic pancreatic proteinase inhibitor on the inhibition of bovine trypsin and human leukocyte elastase. Enhanced MRI T 2 Relaxivity in Contrast-Probed Anchor-Free PEGylated Iron Oxide Nanoparticles. Perivascular epithelioid cell neoplasms: a systematic review of prognostic factors. Neither the two PAF antagonists nor ketotifen had any effect on bronchoalveolar lavage (BAL) eosinophil numbers. To avoid confusion, it is important to clarify the many dimensions of outcome terminology.

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The accuracy of proxy ratings of life-style activities using the Adelaide Activities Profile. Western analysis revealed cross-regulation between the alpha and beta isoforms, because induction of overexpression of one up-regulated the other. Our study compares clinical and therapeutic courses (corticosteroid response, corticosteroid amount, complications) in people with giant cell arteritis before and over 75 years, during the first year of treatment. We investigated the prevalence of RLS in patients suffering from unpleasant sensations in the legs. Without pre-enrichment, this approach could detect 10(4) CFU/g of ground poultry meats.

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Therefore, there is the need to develop alternative strategies to deliver Ag in order to induce immunoprotection. 115 patients with colorectal diseases underwent MS-CT with varying, rectal contrast agents in a prospective study. These results allow to plan a medical action for women with ovarian hypofunction and genital infantilism associated with chronic inflammatory processes of the sexual organs. In a series of cell microinjection studies we found that normal chemotactic responses were restored in WASp macrophages transfected with a full-length human WAS construct. The bricks were either placed around the outer walls (open enclosures), lined up across the middle (wall enclosures) or scattered separately across the floor (complex enclosures).

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We show that homozygosity of the B allele of the proteasome subunit LMP2 increases susceptibility to certain subgroups of JRA, and influences the phenotype of disease, predisposing to more progressive and severe articular disease. In a previous study, the transport of amino acids across the plasma membrane was investigated with fibroblasts from patients with schizophrenia and controls. Each A locus contains several genes separated into two functionally independent complexes termed A alpha and A beta, and the multiple alleles of these genes generate an estimated 160 A mating specificities. Tri13 and Tri7 determine deoxynivalenol- and nivalenol-producing chemotypes of Gibberella zeae. LAA and RAA flow velocities were measured by pulsed-wave Doppler and wall motion velocities with tissue Doppler imaging (TDI) in transesophageal echocardiography.

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Aerosol deposition can be imaged and quantified by the addition of a radiolabel to the aerosol formulation. The orientation of fragments can be described in terms of an induced dipole moment with a small contribution of a permanent dipole. Although the relatively benign side effects of these medications on cardiac conduction and blood pressure allow for more liberal use in the medically ill, these drugs nevertheless have different capacities for adverse drug interactions that must be considered. The mechanisms of resistance to anti-human epidermal growth factor receptor 2 (HER 2) therapies are unclear but may include the tyrosine-protein kinase Met (c-Met), vascular endothelial growth factor (VEGF) and AXL pathways.