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Endoxana (Cyclophosphamide)

Endoxana belongs to a group of drugs called alkylating agents. It works by sticking to one of the cancer cell’s DNA strands. DNA is the genetic code that is in the heart of all animal and plant cells. It controls everything the cell does. The cell cannot then divide into 2 new cells. You have Endoxana into your bloodstream (intravenously) or as tablets that you swallow whole, with a glass of water. Don't chew or break the tablets and, if possible, take the tablets in the morning.

Other names for this medication:
Cyclophosphamide, Cytoxan, Ciclofosfamida, Cryofaxol, Cycloblastin, Cycloxan, Cycram, Endoxan, Endoxana, Genoxal, Neosar, Procytox, Sendoxan,

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Endometrial epithelial and stromal cells were obtained by enzymic dissociation of tissue, and epithelium was separated from stromal cells by sieving. Hypertrophic cardiomyopathy: is a left ventricular outflow tract gradient a major prognostic determinant? We retrospectively studied 267 consecutively enrolled patients with intra-abdominal infections.

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Based on evidence obtained through measurements of enzyme activity, Western blotting, and RNA determinations, the absence of one or both of the constitutive nitrate reductase isoforms has no effect on the metabolite regulation of the inducible nitrate reductase isoform. The ytterbium trifluoride filler in Tetric has a very low water solubility, and it is therefore suggested that the increases in fluoride release from Tetric after exposure to fluoride were most probably due to release of surface-retained fluoride.

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They also indicate that the TH-insulin cells of postnatal and adult mice are not stem cells but are postmitotic cells that appear in the islets after birth. Bursting on the intermediate time scale is generated without need for a slow process having an intermediate time constant, hence phantom bursting.

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In 25 patients, considered high surgical risks according to clinical criteria, systemic and pulmonary hemodynamic parameters were monitored using a flow-directed pulmonary arterial thermodilution catheter before, during and after major vascular surgery. The study was designed to investigate the association between perceived neighborhood safety and LTPA in a nationally representative sample of older adults, and to evaluate SES characteristics as potential effect modifiers in the association between perceived neighborhood safety and LTPA. Hence, if undesired circulatory responses are to be avoided in abdominal surgery, mesenteric anaesthesia appears to be just as important as a careful surgical technique which should be tissue-sawing. In dark-adapted photoreceptor cells of the locust Schistocerca gregaria, prominent sacs of smooth endoplasmic reticulum (ER) oppose the bases of the photoreceptive microvilli. Delayed progression of cytotoxic oedema in focal cerebral ischemia after treatment with a torasemide derivative: a diffusion-weighted magnetic resonance imaging study.

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Mercury distribution and speciation in water and fish from abandoned Hg mines in Wanshan, Guizhou province, China. In all combinations there were no differences between homotypic and heterotypic couples in mating latency. Cardioselectivity is similar to that of metoprolol, and the ability to titrate the effect of esmolol may provide additional assurance that beta-adrenergic blockade will remain within the cardioselective range. Electron-microscopic analysis revealed that both types of gp130 immunoreactivity were primarily associated with the cytoplasmic membrane and were not localized exactly at synaptic sites. EDHs were localized in the temporal region in all five patients who subsequently required the surgical intervention.

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Data were collected in Amazon S3 with no manual data entry, and access to all data was maximally restrictive, logged, and auditable. The biotechnological control of pitch in paper pulp manufacturing. Seven divers performed six dives on consecutive days using compressed gas mixture of oxygen, helium, and nitrogen (trimix), with diving depths ranging from 55 to 80 m. The CBF increase was maximal in frontal, central and parietal regions.

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However, no studies speaking directly to the origins of the relationship, i.e. Long-term effects of exercise on blood pressure and lipids in healthy women aged 40-65 years: The Sedentary Women Exercise Adherence Trial (SWEAT). Calcium salts and/or calcitriol had been taken prior to onset in three patients. This information, based on the latest research, is presented in this article along with the types of hormones available, prescription regimens, side effects, management issues, and possible alternatives to hormone therapy.

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Rudolph Matas--how I remember him: an interview with Dr Michael E. Transport of acidic amino acids by human jejunal brush-border membrane vesicles.

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Treatment of mandibular first molar teeth with endodontic-periodontal lesions in a dog. The versatile source construction suggests that pulse synthesis from sliced supercontinuum may be a useful technique across the 1000 - 2000 nm wavelength range. Propeptide processing of oncostatin M may be important for regulating in vivo activities of this cytokine. Assignment of S100A11 and SELE to porcine chromosome 4 by in situ hybridization.

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The recombinant F proteins were found to be localized at the surface of transfected cells. The centrally active beta adrenergic receptor agonist clenbuterol is currently being evaluated clinically as an antidepressant.

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Experimental principles for interpretation of alveolo-pulmonary reactions We observed that most cell types react to p38 MAPK inhibition with diminished cytokine release, but that this treatment induced increased cytokine release in macrophages.

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The general and functional prognosis of femoral shaft fractures in the elderly is the same as for proximal fractures. In this article, the last 80 consecutive patients are reported after their follow-up visits. We showed previously that Lyn is a substrate for caspases, a family of cysteine proteases, involved in the regulation of apoptosis and inflammation.

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These results implicate O(2)-alkylthymine as a likely candidate for transversion mutagenesis induced by ENU. Fifty-eight subjects including controls, patients with duodenal ulcer, non-operated or treated with a superselective vagotomy underwent endoscopic fundic and antral biopsies. Massive thymic haemorrhage should be added to the reported causes of lethal non-immunological hydrops. The in vitro cytotoxicity of the synthetic lipidic compounds was tested against two different cell lines (P388 and NSCLCN6).

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Chromosomal DNA fingerprinting analysis using the insertion sequence IS6110 and the repetitive element DR as strain-specific markers for epidemiological study of tuberculosis in French Polynesia. The aim of this study was to determine the genetic diversity among isolates of Burkholderia andropogonis from various host plant species and geographic locations. Examples of these new problems include increased Toxoplasma gondii infections in pigs and high dioxin levels in eggs from free-range hens. Likewise, mean eye velocity during steady-state pursuit was reduced by structured visual backgrounds.

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Although the age of 11 years the majority of boys and girls were free of CVD risk factors, at age 17 years more than three-quarters were exposed to at least one risk factor. An imbalance in nucleotide pools can exert a two-pronged attack on both DNA and membranes. This implied that PCDDs/PCDFs in the urban soils originate from the deposition of combustion emissions and that all congeners within each homologue behave identically in air and soil.

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Protein F2, a novel fibronectin-binding protein from Streptococcus pyogenes, possesses two binding domains. Neurological complications of anti-rabies vaccination with the Semple vaccine

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Between 1984 and 1995, CUD using the Kock pouch method was performed on 102 patients, and on 61 patients using the Indiana pouch method, with a mean follow-up period of 83 and 50 months, respectively. The second stage is the evaluation of the degree of probability of physical overload. The patients subjectively ranked the intensity of any pain they experienced for each group of lesions.

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Have the impacts on resource use been valued appropriately in terms of their true costs? The results are explained by postulating that retinoscopic light is reflected from the internal limiting membrane in young eyes and from a layer posterior to the photoreceptors in older eyes. Cleavage within, or removal of, lanthionine ring C essentially abolishes the activity of nisin. A fiber-optic wavelength division multiplexer was employed in the integrated platform to combine the low coherence OCT light source and the femtosecond two-photon excitation laser into the same optical path.

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In contrast to standard donor retention strategies (e.g., mailings, phone calls, text messages), we developed a brief telephone interview, based on motivational interviewing principles, that encourages blood donors to reflect upon their unique motivators and barriers for giving. High-field NMR (13C and 1H) studies of phenindamine are reported which establish structures of the free base and some of its salts in the solute condition.

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Ataxia telangiectasia mutated (ATM) plays a critical role in the cellular response to DNA damage. Complex descriptive, physiologic and hygienic studies covered various occupational groups of physical and mental work and revealed that health disorders probability depends on intensity of occupational factors. The cellular fatty acid, sphingolipid, and isoprenoid quinone compositions of Flavobacterium odoratum, Flavobacterium breve, and Flavobacterium-like groups IIe, IIh, and IIf were determined, using thin-layer, gas-liquid, and reverse-phase high-performance liquid chromatography.

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Family planning initiatives in Africa may be remarkably cost-effective interventions in the development of a nation and be associated with well spaced and healthy children. The expression of SMemb was also increased in epithelial cells in this model.

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The causes of inflammatory dysregulation are not clear in most cases and control of the inflammatory response will be improved, when the timing of and the relations between the mediators are clarified. Since macrophages are a primary source of NO, we compared splenic adherent macrophages from virus-free and virus-exposed chickens. Moreover we obtained the operativity of the glyoxylate cycle in the lipid-rich cells or cells developped on neutral detergents or anionics similar to the fatty acids. The regenerated epithelium gradually exhibited normal immunolocalization of the proteins. Right cerebral hemisphere damage: incidence of language problems.

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Cells of origin of cortical projections to dorsal column nuclei, spinal cord and bulbar medial reticular formation in the rhesus monkey. A study of the blue-light-dependent phosphorylation, degradation, and photobody formation of Arabidopsis CRY2. Method for recording rapid changes of pressure in the human gut. Distributions of transition matrix elements in classically mixed quantum systems. General therapeutic options for patients with acute myelogenous leukemia (AML) are reviewed and specific new therapies are described.

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This study aimed to revisit the etiology and pattern of PHLF and its role in posthepatectomy morbidity and mortality. Among non-injectors, crack users were more likely to have multiple partners and receive money or drugs for sex. Determination of blood brain distribution using octanol-water partition coefficients. Thus, the position of the guanidinium group at Arg-13 of GIIIA must be located in a certain range for its strong interaction with the channel protein.

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Immunopositive neurones were found throughout the central nervous system in the ventral and dorsal nerve cords and the circumpharyngeal and perianal nerve rings. Intrauterine devices are safe and effective contraceptives for type I diabetic women. Fibrous structure of connective tissue of normal human lamina cribrosa

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Are young adults with asthma treated sufficiently with inhaled steroids? The unidentified inhibitor is destroyed by shaking the conditioned medium, by bubbling gas through the medium, or by heating or storing the medium in the absence of cells. Effect of somatostatin on nonesterified fatty acid levels modifies glucose homeostasis during fasting. To study the organization of cells, routine staining was performed.

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Localization by peroxidase-labeled antibodies of bovine chymotrypsinogen. Renal fibrosis is the final common pathway of chronic kidney disease, and its progression predicts the degree of renal dysfunction. In vivo, the drugs were tested for suppression of the PFC response against SRBC.

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Given the heterogeneity in terms of treatment and results, we did not find a univocal trend over the years regarding MCL management (conservative or surgical). We previously reported (1) the neuroprotective effect against the cerebral ischemia under normothermic condition, and (2) the hypothermic effect of the novel compound of 5-HT 1 A agonist, SUN N4057.

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In 5 patients pathological fractures of the irradiated bones occurred, none of them was associated with local recurrence. The diagnostic efficiency of colonoscopy in defining the site and cause of severe hematochezia in the Oriental population is comparable to most Western series. Mutational analysis of this domain indicates that proper subcellular localization and cycling of gpI depend on two different determinants, a tyrosine-containing tetrapeptide related to endocytosis sorting signals and a cluster of acidic amino acids containing casein kinase II phosphorylatable residues. Preliminary results suggest the power of this design to stimulate improvements in guideline implementation while retaining the power to evaluate rigorously effects on patient care. The crucial role of cigarette smoking in the development of pneumothorax is unclear because nonsmokers can also develop primary spontaneous pneumothorax.

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Both NaOCl and CHx were cytotoxic to human PDL cells in a concentration- and contact time-dependent manner. A case of intravascular malignant lymphomatosis presenting as cerebral infarction

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This feature, which is shared by other bacterial pathogens with low sequence diversity, such as Yersinia pestis and Bordetella pertussis renders M. Hemiarthroplasty versus angle-stable locking compression plate osteosynthesis in the treatment of three- and four-part fractures of the proximal humerus in the elderly: design of a randomized controlled trial. Experiments on Bosphorus, CurtinFaces, Eurecom, and Kiwi databases demonstrate that the additional depth information has improved the performance of face recognition with large pose variations and under even more challenging conditions.

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HIV type 1 glycoprotein 120 amplifies tumor necrosis factor-induced NF-kappa B activation in Jurkat cells. Therefore, there is a need to develop novel, nontoxic topoisomerase inhibitors that have the ability to spare normal cells. There were no significant changes in the active renin and aldosterone in patients with primary aldosteronism after treatment. We invoked a language and social psychology lens to investigate how different health professional groups discussed the communication problems and strengths they experienced in handovers.

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We report a case of bladder leiomyosarcoma treated at our department. Secondary lymphedema (LE) resulting from breast cancer surgery has continued to be an ignored medical diagnosis in U.S.

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Mismatch in elastic properties around anastomoses of interposition grafts for hemodialysis access. Phenytoin-induced lingual tonsil hyperplasia causing laryngeal obstruction. IL-1 beta produced a rapid (within 1 h) concentration-dependent increase in O2-, as detected by ferricytochrome c reduction and lucigenin-enhanced chemiluminescence.

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Over the past 2 1/2 years we have managed four patients with this problem by mobilization of the fixated cricoarytenoid joint, arytenoid-pharyngeal mucosal advancement flap, brief splinting of the arytenoids in the fully abducted position, and early speech therapy. In vitro DNA binding assays reveal that CpG-binding protein contains a single DNA binding domain comprised of the CXXC domain and a short carboxyl extension. Oxidative stress involves the adverse effects of oxygen and other free radicals on living tissue.

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In a selective screening for antifungal metabolites, six new clavam antibiotics, clavamycins A, B, C, D, E and F, have been detected from two variants of Streptomyces hygroscopicus NRRL 15846 and NRRL 15879. Interaction-induced dipoles of hydrogen molecules colliding with helium atoms: a new ab initio dipole surface for high-temperature applications. Induction of specific transplantation immunity by oral immunization with allogeneic cells. Endophytic bacteria reside within plant hosts without causing disease symptoms.

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As computer hardware becomes less expensive and computer software more sophisticated and easy to use, more physicians are using computers to take notes and keep records. Following an inflammatory stimulus, Th2-derived cytokines drive the maturation process of these MCps, leading to the mature mucosal MC hyperplasia associated with events such as an intestinal helminth infection and possibly human allergy such as asthma and rhinitis. (2009) find that intrinsic protein disorder and promiscuous molecular interactions are strong determinants of dosage sensitivity, explaining in part the toxicity of spiroctan 25 mg promethazine dosage-sensitive oncogenes in mice and humans. In the United States, competent patients have the right to refuse medical care, including artificially administered nutrition and hydration, and courts also have extended this right to incompetent patients. Polymyositis is a rarely reported complication of chronic graft-versus-host disease (GVHD) with only 8 cases described in the literature.

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A significant difference has been reported between rates of morbidity and mortality for elective esophagectomy performed at low-volume centers versus high-volume centers. Apart from retention, recovery and stabilisation, other advantages to enzyme immobilisation have emerged, such as enhanced enzyme activity, modification of substrate selectivity and enantioselectivity, and multi-enzyme reactions. An orthodenticle-related protein from Strongylocentrotus purpuratus. However, cells sensitized either with 0.1 or 0.05 mg of antigen per ml and reacted with antisera absorbed with 10 or 1 mug/ml showed the presence of a specific antigen in each metronidazole gel 0 75 strain of S.

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In vitro, expression of CS-CRYP-alpha enhanced neurite outgrowth, while CS-PTP-delta inhibited neurite outgrowth in bimoxyl la bimeda ireland a substrate-dependent manner. In addition, a coding of local topological constraints associated with each secondary and tertiary structural motif is introduced. TS develops as a result of a mutation of one of two genes, TSC1 or TSC2, which encode for hamartin and tuberin, respectively.

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No significant difference in the changes in serum MDA-LDL was observed between patients with acute myocardial infarction and stable angina pectoris treated by PTCA. Repetitive transpositions of mitochondrial DNA sequences to the nucleus during the radiation of horseshoe bats (Rhinolophus, Chiroptera). Our data suggest that the higher prevalence of the acute subtype of ILD in patients with CADM results in a higher mortality rate for patients with CADM-ILD. A total of 80 patients was treated using a short-time high-dosage schedule of cytostatic therapy with cyclophosphamide, 5-FU, vincristin and methotrexate. Although magnetic resonance imaging has become the modality of choice for the diagnostic evaluation ketoconazole shampoo ultrafarma rio of cerebral vascular malformations, cerebral angiography remains indispensable for the evaluation of cerebral arteriovenous malformations.

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In their natural hosts these conditions are characterised by prolonged incubation times prior to the onset of clinical signs of terminal disease. LPS increased total glutathione (tGSH) levels after 2 h treatment but decreased oxidized usa olympics gymnastics 2012 alternatives to coumadin glutathione (GSSG) content which lead to a marked decrease in GSSG/tGSH index. We also studied the relation between gait and falling in institutionalized patients with Alzheimer-type dementia. This study reports the first records of an underwater acoustic repertoire in an aquatic chelonian.

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For a period of 400 min the epithelium of one of the corneas was exposed to one of seven test osmolalities (200-425 mOsm/kg), whereas womenra uk the other cornea was used as a control (305 mOsm/kg). The majority of the sheep showed no preference for an alternative, uncontaminated source of water.

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Into dangerous and complex systems with high degree of interactivity between its components, the variability is present at all time, demanding a high degree of control of its operation. An evaluation of community-based HIV services for women in New York State. Nuclear run-on studies suggest that a change in the rate of transcription cannot explain the increase in steady-state mRNA levels. Most metabolic disorders of genetically obese Zucker rats are reversed by adrenalectomy and are restored by corticosterone treatment, thus suggesting that a functional hypercorticosteronemic state is involved in risperidone actavis 2 mg the pathogenesis of the obesity syndrome in fa/fa rats.

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A case is presented in which, following the failure of several surgical and non-surgical procedures to control the increasingly severe pain in an amputation thumb stump, a toe transfer metronidazole alcohol 48 hours after hitting was carried out, successfully relieving the symptoms without transfer of the pain to the donor site. The emulsion-inactivated vaccine has high immunological activity and induces reliable increases in the level of secretory immunoglobulin A to influenza viruses A and B in protective titers in nasal secretions and saliva of volunteers after one oral administration. This variable receptor subunit expression provides an explanation for the diversity of pharmacological and single-channel responses we have observed in individual neurons. The stimulatory effect of testosterone was insensitive to the action of actinomycin D both in vivo and in vitro.

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Therapeutic Efficacy Comparison of 5 Major EGFR-TKIs in Advanced EGFR-positive Non-Small-cell Lung Cancer: A Network Meta-analysis Based on Head-to-Head Trials. Both the physical examination and laboratory data of these pantoprazole and omeprazole in the treatment of reflux oesophagitis cases were normal. For the female subjects, the values were 2356 times and 419 seconds.

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However, diagnosis of appendicitis is not always straightforward. Regulation of the activity of M-phase promoting factor through protein kinase A-mediated pathway in LP1-1 cells. Obstructive sleep apnea is associated with left ventricular nortriptilina 50 mg efeitos colaterais (LV) dysfunction, oxidant stress, and chronic intermittent hypoxia (CIH). There have been some recent reports of patients with abundant NFT with the predominant involvement of the allocortex but no or very little senile plaque. Prolonged epidural blockade with subnarcotic doses of morphine was included in the complex of postoperative measures in 53 patients.

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Synergistic decrease of clonal proliferation, induction of differentiation, and apoptosis of acute promyelocytic leukemia cells after combined treatment with novel 20-epi vitamin D3 analogs and 9-cis retinoic acid. Avoidance personal goals and the personality-illness relationship. Microtubule stabilization hydroxyzine hydrochloride pamoate and potentiation of taxol activity by the creatine analog cyclocreatine. Promising stool-based screening tests for colorectal carcinoma (CRC) rely on detection of exfoliated colonocytes or their contents. The CSF/serum albumin ratios, CSF/serum IgG ratios and the CSF-total protein concentrations were higher in men than in women among the patients.

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Emergency treatment of migraine attacks metronidazole gel patient reviews with particular reference to agonists of 5-HT1B/1D receptor Recently, we have shown that keratinocyte cell line A431 can function as an antigen presenting cell (APC) and hence can be used as a model to differentiate between an allergen and irritant molecule. Quality of life measurements in patients with malignant disease: a review. Prevalence of obstructive sleep apnea-hypopnea syndrome in adults aged over 20 years in Fuzhou city