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Retrospective study of patients with severe P falciparum malaria admitted to the medical ICU of a university hospital infectious diseases department. Dynamic contrast-enhanced MR imaging of the water fraction provides additional valuable qualitative information about structural changes of the hematopoietic element. However, two quinazolines and four tetrahydroquinazolines were both potent and selective inhibitors of the P.

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The role of reactive oxygen species in signalling from chloroplasts to the nucleus. However, effect of paclitaxel on HCC has not been adequately addressed. However, the process has mainly been studied by nonspecific bulk degradation assays using radiolabeling. Expression of the anti-apoptotic Bcl-2 protein in human term placenta does not seem to be influenced by parturition.

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Effects of response alteration and different instructions on proactive and retroactive facilitation and interference. Results indicated that the lack of development of a hand preference in children with autism was not a direct function of their cognitive delay, as the children with developmental delays showed a dissimilar pattern of hand preference.

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The data of the National Institute of Public Health and Environmental Protection concerning the prevalence of drug-resistant tuberculosis during the period 1990-1994 were analysed. Isoflurane and sevoflurane impair left ventricular relaxation in dogs with fixed heart rate

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In this work, we characterized the RNAalpha promoter region, and by using promoter fusion and rifampicin experiments we were able to demonstrate that iron regulates RNAalpha synthesis posttranscriptionally by stabilizing RNAalpha half-life rather than enhancing transcription initiation. The method is a promising one although further studies using more suitable isotopes and/or monoclonal antibodies are required to increase its sensitivity.

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Injections of mixtures prepared from crushed tablets contain insoluble particles which can cause embolisms and other complications. To investigate the role of connective tissue growth factor (CTGF) induced TGF-beta 1 in the transdifferentiation of human hypertrophic scar fibroblast (HSFb). Outgrowth of chondrocytes from human articular cartilage explants and expression of alpha-smooth muscle actin.

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Two SH3 domain-containing cytosolic components of the NADPH oxidase, p47phox and p40phox, are shown by analyses of their sequences to contain single copies of a novel class of domain, the PX (phox) domain. Changes in proteinuria have been suggested as a surrogate outcome for kidney disease progression to facilitate the conduct of clinical trials. A series of lysosomal protease-sensitive peptides attached to doxorubicin (DOX) was prepared as model substrates for internalizing anticancer immunoconjugates and potential antimetastasis prodrugs. Distinct mechanisms of neurotransmitter release from PC 12 cells exposed to lead. Cleaning of machines for pharmaceutical production: microbiological investigation to establish validation procedures

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However, EGF strongly inhibited the expression of WDNM1 and SGP-2 genes. This association reflects causality running in both directions: poverty breeds ill-health, and ill-health keeps poor people poor. To examine the relationship between body mass index and 24-hour urine constituents in a population of stone-forming patients. Exploring the competition between localization and delocalization of the neutral soliton defect in polyenyl chains with the orbital optimized second order opposite spin method. The bFGF effect was accompanied by increased TERT protein expression and a rapid but transient increase in TERT mRNA.

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Volume-mediated pulmonary responses in liver transplant candidates. Prevention of AIDS in Sri Lanka: are we doing the best for our people?

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The hidden language of flowering plants: floral odours as a key for understanding angiosperm evolution? Egr-1 mRNA and protein expressions were examined by RT-PCR and Western-blot analyses. A review of physical and psychological factors in vulvar vestibulitis syndrome. Endoscopic retrograde cholangiopancreatography was attempted in 1 patient. The authors maintain that only an overall evaluation of the anamnestic, clinical and laboratory findings will enable the physician to make a correct diagnosis and exclude from the start, via coordinated protocols, any silent ischaemic disease, and also a series of clinical conditions that the ECG can reveal as this disease.

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Evaluation of skin sensitization potential of melatonin and nimesulide by murine local lymph node assay. Urinary bladder invasion had lower ADC values compared with normal urinary bladder wall.

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Ten potential allergens (Bermuda grass, Olive tree, Parietaria, Alternaria, Cat hair dander, Dog hair dander, Mite DPT, Mugwort, Birch tree and Timothy grass) common to the Mediterranean area, were utilized. baumannii is thought to possess a great deal of intrinsic resistance to several antimicrobial agents, including chloramphenicol, although the mechanisms involved in such resistance are not well understood. The purpose of this study was to determine the lifetime incidence of mental disorders in caregivers involved in maltreatment and in their maltreated child.

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The introduction of a reference method, in combination with the NBSB 80/602 human liver reference preparation, is the second important step towards the accurate standardisation of ferritin immunoassays. We have found that azide-resistant mutants of Salmonella typhimurium and of other bacteria studied produce a substance which inactivates the azide. Laser therapy in the treatment of congenital vascular abnormalities. The possibility of a small-cell malignant melanoma should be considered in the assessment of cutaneous and non-cutaneous small-cell neoplasms.

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Subsequent surgery, which was required in both patients (due to failed embolization), was also greatly aided by the demonstration of the exact extent of the AVMs on axial CT images. The aim of this multicentre study was to assess the efficacy, safety and tolerability of tacalcitol (4 microg g(-1)) ointment (Curatoderm, Hermal, Reinbek, Germany) applied once daily over a treatment period of 18 months. Data were obtained from 1014 American and Canadian patients with ALS who died while participating in a large observational registry (the ALS Patient Care Database) during the past four years.

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Previously published reports have attempted to clarify the possible role of fibrin glue in the inhibition of the formation of intrapericardial adhesions following cardiac surgery. Initially, the total urinary proteins were separated by 1-D and 2-D electrophoresis and then subsequently analyzed by Matrix Assisted Laser Desorption Ionization-Time of Flight and Mass Spectrometer (MALDI-TOF/MS). New analytical equations are derived for spectral resolution and SBR of LGI based FTS systems. The factor appears to be a protein or associated with a protein but not an acrosomal protein.

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Is Long-Term Low-Dose Aspirin Therapy Associated with Renal Dysfunction in Patients with Type 2 Diabetes? These results are consistent with the express train model of Polynesian origins. Effect of lateral forces on the movement of myosin-coated beads on actin cables studied using a centrifuge microscope. The campaign against tuberculosis was one of the main health tasks undertaken by the Francoist regime from the beginning of the Civil War. As suggested, endogenous reserpine-like substances participated in the autoregulation of free and bound biogenic amines level.

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Since the detection of PAH genotoxicity requires the presence of S9, and since a higher level of genotoxic activity was noted following sediment extract exposures with no S9 present, this suggests that the extracts contain a complex mix of chemicals, some of which express genotoxic activity. Clinical, virological and serological response of the West African dwarf sheep to experimental infection with different strains of Rift Valley fever virus. As a first step in this direction, we sought to determine the specific gene expression profile of NEC. We also describe the use of a newly developed monoclonal antibody to P.

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Clinical fields, such as posterior neck node (PNN), were compared. Significant complications leading to mortality included cardiac tamponade (five cases) due to left ventricle apical perforation (3/5 cases). Tissues obtained were examined by light and electron microscopy to identify structural components.

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An epidemiological study of hypertension and its determinants in a population in transition: the THUSA study. Influenza A/Port Chalmers/1/73: intrafamilial spread and the effect of antibodies to the surface antigens. Blood coagulation at the site of microvascular injury: effects of low-dose aspirin.

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Those from all six centers tested formed bone, but the quantity formed was highly variable and BMSCs from only three centers supported hematopoiesis. The HbA1C of NSZ mice was slightly increased from 5 to 20 weeks while the HbA1C of KK-Ay mice was markedly increased from 5 to 10 weeks.

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Gene engineering has been shown to have the great potential for improving the resistance to these stresses as well as the nutritional quality of sweetpotato. The interleukin 1 receptor antagonist gene allele 2 predicts pouchitis after ileal pouch-anal anastomosis in ulcerative colitis. polyphenols such as resveratrol, have emerged as promising agents for cancer chemoprevention and therapy, since they interfere with various major signaling cascades that are aberrantly regulated in cancers. The plasmid-associated operons containing genes for the mundticin L precursor, the ATP binding cassette (ABC) transporter, and immunity were cloned and sequenced.

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Biomonitoring the intake of garlic via urinary excretion of allyl mercapturic acid. Escalation of therapy for acute disease relies primarily on H2 receptor antagonists given in conventional dosages. In this study, we analyzed the expression of Met/HGF receptor by Western blotting and immunohistochemistry in frozen samples of 87 primary tumors of bone and soft tissues. The combination of gene-targeting techniques in mouse embryonic stem cells and the Cre/loxP site-specific recombination system has resulted in the emergence of chromosomal-engineering technology in mice.

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