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The parotid gland dysfunctions leading to xerostomia observed in a mouse model of cGVHD may be of clinical importance. Maintaining vertical divergence of about 2 diopters for 6, 8, or 10 min was shown to yield an induced vertical phoria (IVP). Social skills training for drug prevention in high-risk female adolescents. Unilateral kidney blood flow measurement using the 81Rb/81mKr ratio.

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Isomerization of DNA-bound distilbazolium ligand induced by electron transfer from photoexcited tris(1,10-phenanthroline)Ru(II). TraG-like proteins also function as essential components of type IV secretion systems of several bacterial pathogens such as Helicobacter pylori. Induction of islet cell protection against inflammation could therefore be postulated to be a powerful means to improve overall graft fate. histolytica (strain HM-1: IMSS) were cloned in the plasmid vector pTZ18R. Clonal dissemination and colony morphotype variation of vancomycin-resistant Enterococcus faecium isolates in metropolitan Detroit, Michigan.

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Initial system design method for non-rotationally symmetric systems based on Gaussian brackets and Nodal aberration theory. Positive tumoral FOXP3 expression was significantly related with smaller tumor size, tubular tumor type, lower histological grade, lower T stage, lower recurrence rate, less lymphatic invasion, and less neural invasion. Expression strategies for the candidate antigens have focused increasingly on producing more natural antigenic structures, for example, virus-like particles.

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Unclear orders, both written and verbal, need to be clarified: Never make assumptions about the drug, dose, route, or frequency. Randomly selected CHWs were observed managing sick outpatient and inpatient children at a hospital, and their management was compared with that of an expert clinician who used the algorithm. A new mouse model of H-2 haploidentical peripheral blood stem cell transplantation from double donors (DHSCT) has been successfully established by reducing conditioning intensity and increasing graft cell numbers from double haploidentical donors without GVHD prophylaxis.

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Experimental formation of goiter in exencephalic fetal rats subjected to maternal hypervitaminosis A. Further investigation will be required to determine molecular specializations of the apical membrane of M cells which may facilitate interactions with antigenic material. Higher mortality associated with reduced GFR after AMI is not accounted for by differences in treatment factors, underscoring the need for novel therapies specifically targeting the pathophysiological abnormalities associated with kidney dysfunction to improve survival.

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Both angiotensin II and vascular endothelial growth factor are angiogenic agents that have recently been implicated in the pathogenesis of proliferative diabetic retinopathy. Radiotherapy must be planed on the basis of considering the therapeutic ratio with a 3-dimensional treatment planning technique which is an important role in radiotherapy because they are essential in target localization. Docetaxel (Taxotere), an analogue of paclitaxel, was tested in a phase II study in advanced renal cell carcinoma.

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Oral hygiene habits and periodontal knowledge in a group of Canadian adults--a pilot study. The patient with dyspnea: specific expectations of nursing assistance. In this setting, NVP-BEZ235 selectively induced cell death in cell lines presenting either HER2 amplification and/or PIK3CA mutation, but not in cell lines with PTEN loss of function or KRAS mutations, for which resistance could be attributed, in part to ERK pathway activity. The results of the 25 study patients showed small and not significant improvements in all functional index scores (BASFI -0.5 points, DFI -1.1, and HAQ-S 0.17), whereas improvements were significant in BAS-DAI, BAS-G, and stiffness-VAS (-13 mm, 13 mm, and -11 mm, respectively) after the 3-week inpatient course.

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Acrokeratosis paraneoplastica (Bazex syndrome) associated with metastatic cutaneous squamous cell carcinoma. Apoliprotein E (apoE) is a potent suppressor of interleukin 2- (IL2-) dependent T lymphocyte proliferation. The human genome sequence and the analysis of multifactorial traits. Cells with argyrophil granules were searched for in 131 consecutive specimens obtained from endometrial curettage.

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Strong differences between nemesia roots growing in agar or in paper-pulp substrates were evidenced through scanning electron microscopy. PTP-SL and STEP protein tyrosine phosphatases regulate the activation of the extracellular signal-regulated kinases ERK1 and ERK2 by association through a kinase interaction motif. Plasma glucose, prolactin, cortisol, ACTH, CRH and AVP were measured at intervals over a 3-hour period.

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The brains of the surviving 30 mg/kg rats were severely hydrocephalic, with little cortex remaining. Pyruvate can be replaced with alpha-ketoglutarate or oxaloacetate, or with amino acids capable to transaminate to these three metabolites in the presence of exogenous alpha-ketoacid acceptors. The furan has previously been reported from the Basidiomycete Irpex lacteus, while dermatolactone is a new compound the structure of which was determined by spectrosocpic methods.

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The effect of molecular charges on renal accumulation of 111In-DTPA-labeled low molecular weight (LMW) peptides was investigated using 111In-DTPA-octreotide derivatives as models to design radiolabeled peptides that are taken up less by renal cells. A major practical contribution came from the Kempner rice diet, an effective antihypertensive dietary treatment which included a severe restriction of salt intake.

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To determine the incidence of self-reported significant hip pain using a nationally representative sample of older adults in the United States. To elucidate its state (during depression only) and trait (during depression and recovery) related neural bases, we investigated medication free depressed, recovered, and healthy individuals with functional MRI while they memorized and recognized happy and neutral face stimuli. Consecutive men undergoing Roux-en-Y gastric bypass (RYGB) participated in a prospective, longitudinal study. Five cases of amebiasis of the genital tract involving the cervix, vulva and penis are described. Since the nursing staff may be responsible for maintaining cerebral perfusion and normal ICP with barbiturates, mannitol, fluids, and pressor agents, it was thought that a detailed description such as presented might be useful.

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The resulting images provided excellent anatomic detail of the structures of the central nervous system and associated formations. Total medical costs of treating femoral neck fracture patients with hemi- or total hip arthroplasty: a cost analysis of a multicenter prospective study. These different patterns of morphology and cell death in the embryos of ZnD dams were associated with different patterns of maternal food intake.(ABSTRACT TRUNCATED AT 250 WORDS) Over eighty cases have been reported, many of which had a hematologic malignancy including neutropenia.

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SFL production by carcinoma cells induces the aggressive properties of nonproducing cells in vivo via a community effect. Contrast discrimination, non-uniform patterns and change blindness. Randomized studies are needed to objectively evaluate the impact of process-of-care markers on CAP outcomes. Clinical downstaging of uterine cervix by paramedical personnel. The discussion is based on the assumption that more effective participation by family physicians in the treatment of chronic psychiatric illness requires active attention throughout the continuum of medical education.

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Self-perceived health is related to functional status, morbidity and mortality and is an important measure in determining health status and health-related quality of life (HRQOL) scales. The six STR loci included in this study were found to be highly polymorphic, and may provide useful markers for genetic analysis.

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This model can contribute to inform clinical decision-making and optimise clinical trial design. Because ADHD is heterogeneous with respect to psychiatric comorbidity, familiality, and learning disabilities, it was hypothesized that such features might influence the severity and pattern of neuropsychological function in ADHD. Pregnancy is associated with increased levels of soluble (s) human leukocyte antigen (HLA)-G molecules, while during abortion these molecules are decreased. High (2-10 microM) but not low (0.01-1 microM) concentrations of heme-hemopexin increase, albeit transiently, the protein carbonyl content of mouse hepatoma (Hepa) cells.

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Hierarchies according to the level of evidence of source data, before their integration in the synthesis, in the matter of therapeutic efficacy Purification and sequence determination of a yellow protein from sexually mature males of the desert locust, Schistocerca gregaria.

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We report our experience with urate-oxidase in three heart transplant recipients with severe polyarticular and tophaceous gout, a history of leukopenia under allopurinol and unresponsiveness or contraindications to uricosuric agents. A relationship between gene expression and protein interactions on the proteome scale: analysis of the bacteriophage T7 and the yeast Saccharomyces cerevisiae. Dapoxetine: an evidence-based review of its effectiveness in treatment of premature ejaculation. Although Dissociative Identity Disorder presents with polysymptomatology, much treatment progress can be achieved during pre-integration and dramatic improvement follows integration. Different patterns of TGF alpha and TGF beta expression were seen, however, within the epithelium of rats with acute intestinal injury compared with untreated controls, while the expression of these peptides within the lamina propria was not changed.

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Rotavirus persistence in malabsorption syndrome: virus assessment by immunofluorescence in small intestine biopsies in relation to antibody titres. The Oswaldo Cruz Institute and its importance in the Brazilian society.

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Full thickness biopsies of affected skin and fascia from one patient with diffuse fasciitis and eosinophilia (DF), two patients with generalized morphea (GM), and five patients with progressive systemic sclerosis (PSS) of recent onset were examined for the expression of transforming growth factor beta 1 (TGF beta 1) and type I procollagen genes by in situ hybridization with human sequence-specific cDNA. Due to its high sensitivity, reproducibility and its ability to quantify mRNA transcripts, the RPA is a useful tool for investigating expression of low abundant receptor genes and their regulation when only very small amounts of tissue are available. Primary varicella-zoster infection is very common during childhood and few patients develop complications. To compare the diagnostic value of endoscopic ultrasound (EUS) and endoscopic retrograde cholangiopancreatography (ERCP) in the differentiation of malignant from benign masses in the pancreatic head.

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Two-minute ethanol treatment resulted in complete destruction of microvilli and significant separation of intercellular junction. Other limiting factors include mutation class, genetic profile, drug interactions, adverse effects, and cost. The present study shows that the personal costs and difficulties incurred by rural and remote residents when accessing specialist treatment can be reduced if a visiting specialist service is available.

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Significant differences in transcriptional activity of Cg-GnRH encoding gene were recorded in the ganglia along the reproductive cycle and according to trophic conditions with a higher level in fed animals compared to starved animals. Hypocretin-1 levels were measured in CSF samples, obtained from 284 preterm (25-37 gestational weeks) and full-term infants in the first 4 months of life and 35 older children (ages 0.5-13 years), in a tertiary hospital.

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Brief alcohol harm reduction effort demonstrated a significant effect on sexual violence and engagement in sex trading. Many studies confirm the relationship between attachment disturbances and (the severity of) eating disorders, however among them only one Hungarian study can be found. The utility of this system was further demonstrated by transformation of H. Radiographs show no signs of implant loosening, osteolysis, or wear of the bearing surface.

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Aneuploidy is a hallmark of most human cancers that arises as a consequence of chromosomal instability and it is frequently associated with centrosome amplification. Skin smear values indicated contamination by direct contact with dust from fertilizers and this may contribute to skin cancer induction in this risk population. At present, recombinant activated factor VII cannot be recommended for routine use, although BP lowering should generally follow conservative guidelines.

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Twenty-four-hour esophageal pH monitoring is a valuable tool for preoperative cough-reflux correlation. This retrospective cross-sectional study compared the distress level of YAs (18-39 years old) with that of middle-aged (40-64 years old) and senior adults (65-90 years old) using the Distress Thermometer (DT) and associated Problem List (PL). This article specifically addresses the current status of drug development in the area of hormonal and biologic therapies for SLE. The FM patients were assessed using the following self-reported questionnaires: the Medical Outcomes Study Short-Form Health Survey, the Fibromyalgia Impact Questionnaire, the Brief Fatigue Inventory, the Beck Depression Inventory, the State-Trait Anxiety Inventory, the Self-Efficacy Scale, and the Social Support Scale. Cytoskeletal modulators and pleiotropic strategies for Alzheimer drug discovery.

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Proton MRS with TE of 30 ms may safely be used in combined contrast-enhanced MRI/MRS protocols. This study was also the first to estimate the percentage of EMS professionals who self reported the utilization of hearing protection.

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Finally, using recent studies from our laboratory, we will demonstrate the importance of both tumor cell and host stromal cell production of MMP-9 in tumor progression. Whether intestinal transplantation will become an alternative for the stable patient on total parenteral nutrition rather than a salvage procedure for when total parenteral nutrition fails remains to be seen. Conformational properties and stability of tyrosine hydroxylase studied by infrared spectroscopy. Transport of iron from the mother to the fetus is essential for the normal development of the fetus and abnormalities in the transferrin receptor (TFR) on the placental trophoblasts might have some crucial effects on the fetal iron metabolism. In contrast, the level of EGF-dependent EGF-R-tyrosine phosphorylation was not decreased, compared with non-irradiated cells.

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Cross-modal tasks generated greater activation in posterior heteromodal regions including the supramarginal and angular gyri (BA 40, 39). This paper opens with a description of the different computer services used in radiology and how they relate one to another. The characteristic distance and mechanism of energy transfer are reported. Ammonium ions and glutamine inhibit sporulation of Coprinus cinereus basidia assayed in vitro. Cholera toxin (Ctx) and its close relative, Escherichia coli heat-labile enterotoxin (Etx) have long been established as potent mucosal and systemic adjuvants.

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Its objective is to provide a unified definition of IVF and to outline the investigations necessary to make this diagnosis. The crystal structure of one of these with bound ligand has been determined at 1.2 A resolution. After laparoscopic enucleation of intramural myomas in eight women, the uterine wall defect was reconstructed with a single continuous spiraling suture.

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A validated self-administered questionnaire on Rome III criteria for diagnosing FC and its predisposing factors was filled by each participant in a classroom setting. One population was normal and the other population contained alpha 2(I) chains which had a basic charge shift localized to a peptide from the carboxyl-terminal end of the triple-helical domain. The potential cellular and molecular mechanisms underlying memory formation mediated by NA are discussed.

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Rapid intermolecular dipole-dipole interactions are required to account for theestimated dipolar contribution to T1. Determination of cardiac output and other reference physiology parameters in lightly anesthetized dogs. The effects of regulatory agents on TGFbeta expression by the bovine OSE were examined. Framingham functions were developed to calculate overall coronary heart disease risk.

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TH induces a normal physiological phenotype by binding to nuclear TH receptors that regulate expression of specific genes which promote cell survival and enhance contractile function. American Indian and Alaska Natives youth and adults experience higher rates of type 2 diabetes and mental health problems than the general United States population.

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These binding proteins are based on antibody single-chain variable fragments and activate fluorogenic dyes, which only become fluorescent upon activation and do not fluoresce when free in solution. A protein reacted with anti-vitronectin antibody accumulates in tumors derived from B16F10 melanoma cells. Enzymatic activity and its activation energy were determined as a function of temperature and pH. Towards a novel classification of human malignancies based on gene expression patterns. three times a week for five weeks, then 30 mg kg-1 for three weeks) did not lower blood pressure in 17 and 33 weeks-old spontaneously hypertensive rats (SHR).

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Due to the cost and time benefits associated with patients and physicians, outpatient surgeries continue to become more and more popular over time. Myotonic dystrophy with a variable symptomatology and favorable clinical prognosis in a large family Different patterns of association existed between acculturation and physical and mental health among Arab Americans.

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Some VTs associated with cardiac sarcoidosis are due to reentry, and inducibility of VT is not associated with the activity of cardiac sarcoidosis. The frequent mixing of d and other estimates of d in past meta-analyses, therefore, may have led to biased effect size estimates and inaccurate significance tests.

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LY 83583 interferes with the release of endothelium-derived relaxing factor and inhibits soluble guanylate cyclase. Measurement of organic vapors at sub-TLV concentrations using fast gas chromatography. The potencies of DMG-doxycycline and DMG-6-demethyl-6-deoxytetracycline were unaffected by the ribosomal tetracycline resistance factors Tet(M) and Tet(O) in cell-free translation assays and whole-cell bioassays with a conditional Tet(M)-producing E. Studies on L-arginase in developing rat small intestine, brain, and kidney. Therapy of long tubular bone sarcomas using the 25 MeV betatron longitudinal irradiation technic

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The NCLs result in premature death due to the absence of curative therapies. Neuroimaging studies show modest evidence of macrostructural, microstructural, functional and neurochemical changes in some athletes. Previous studies in this stream have revealed that cytochrome P4501A activity, liver somatic indices, macrophage aggregates, and parasitic liver lesions are significantly elevated in sunfish with the degree of impact decreasing with distance from the contaminant source. Such expression is consistent with theories that CD43 plays an anti-adhesional role, and that cleavage occurs during cellular activation. Furthermore, we wanted to study which role the EGFR and the laminin receptor integrin subunits alpha3 and beta1 play during glioma cell invasion.

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Among the host strains tested, the crude violacein production by the recombinant C. This pressure dependence of the PMF is caused by the growing nonpolar contribution at higher pressures.

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Baseline patient characteristics were compared with outcome parameters during the first 6 posttransplant months (i.e., plasma C-peptide, glycemic variability, and gain of insulin independence). Egg phosphatidylcholine decreases the lymphatic absorption of cholesterol in rats. Therefore, this analogue associated to standard insulin replacement could be useful in the control of unstable diabetes.

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The purpose of this study was to evaluate the construct validity of the Continuous Attention Test for Children (the CAT), a clinical measure of vigilance. It is observed that the situation in f levels is more complicated than the d levels because the characteristics of the crystal field splitting for f levels does not only depend on the the local point symmetry of the compounds. The problem of sporadic spotted fever in Central and Western Europe Low serum cholesterol is correlated to suicidality in a Korean sample. The technique is cost-effective and quick, making bilateral repairs possible under the same anaesthetic.