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A simplified PET protocol using 13N-ammonia or 82Rb and simple flow models provide noninvasive measurement of CFR up to six times baseline flow throughout the heart and diagnostic image quality for routine clinical application. Incorporation of an organic phosphate in isolated cell nuclei in vitro We examined this by attaching a small molecule directly to engineered cysteines in an antibody.

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Both the carcinomas and the background mucosa of multiple EGCs have an unstable status, since they more commonly possess the hybrid phenotype of the stomach and the small intestine than does solitary EGC. Chemistry and physiology of metabolic chemically important acids A more sensitive baroreceptor reflex was found in the fetal group in that a given blood pressure response resulted in a significantly larger bradycardia and the calculated gain of the reflex was higher. These findings show that MDMA has obvious addictive potential for reinstating drug-seeking behavior and that METH can be an effective stimulus for reinstating MDMA-seeking behaviors.

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A total of 142 candidate MOR, 52 V2R/OlfC, 32 TAAR and two FPR putative genes were identified. Sixteen rabbits were reconstructed with autografts and the remainder with allografts.

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Deterioration and repair of lead paint on steel structures can result in contamination of the ambient environment but other sources of lead such as from past use of leaded paint and gasoline and industrial activities can also contribute to the contamination. The acceleration of cosmic-ray protons in the supernova remnant RX J1713.7-3946. Immunoreactivity data suggest that heterogeneity among ghilantens is due in part to amino acid substitutions at their carboxyltermini. In order to investigate the differences and similarities between EF-Tu and IF2 we have created point mutations in the G-domain of IF2, Thr445 to Cys, Ile500 to Cys, and the double mutation. Cocaine dependence has also been linked to dysregulation of stress response and the hypothalamic pituitary adrenal (HPA) axis which may differ between genders.

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Every lot of human normal gamma globulin (IMIG or IVIG) having high anti-tetanus activity may be an acceptable alternative to specific tetanus immune globulin. The function and biological role of the secretions released by these glands are discussed. Radiation therapy, surgery and other forms of therapy are only included in special treatment situations, particularly for different local problems. The zen protein exists as a monomer in solution with a molecular weight of about 40,000.

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the new host environment, may lead to mutations in the p53 gene. Migraine with aura (MWA), migraine without aura (MwoA), and hemiplegic migraine patients were studied between attacks by (31)P MRS imaging using a 3-T scanner. CCSP immunoreactivity was found in nonciliated bronchiolar epithelial cells from 12 weeks of gestation onward. A 3-dimensional gait analysis was performed using an optoelectronic system equipped with a force platform.

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In the germinal and supporting cells of the undescended testes, the amount of galactose residues in the complex carbohydrates decreased from the prepubertal to post-pubertal periods. Thus, GOT1 plays an important role in energy metabolism and ROS balance in chronic acidosis stress. DNA probes from the L6 rust resistance gene of flax (Linum usitatissimum) hybridize to resistance genes at the unlinked M locus, indicating sequence similarities between genes at the two loci.

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Expectant management of giant PP is associated with higher morbidity and mortality than small PP suggesting that earlier external drainage, before clinical deterioration, may be beneficial. Localized polyarteritis nodosa: cases involving the lower extremities and the breast. Percent free PSA should be utilized in patients with a total serum PSA value between 3.0 and 10.0 ng/mL.

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Heine-Medin disease: successful investigation of regression of paralysis with ultrasonic therapy HLA-DR expression on lymphocyte subsets as a marker of disease activity in patients with systemic lupus erythematosus.

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Inhibitory effect of alpha-2 adrenoceptor antagonist (DG-5128) on intractable asthma The Lawson system was used successfully in 43 of the 49 successful nephrostomies (88 per cent). The noninvasive calculation requires complicated formulae, which can be, however, easily implemented in computerized algorithms, allowing the adoption of this index in the clinical evaluation of patients.

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The intensity and prevalence of parasitism by Ascogregarina barretti (Vavra) in Aedes triseriatus (Say) did not differ between tires and tree holes in field samples taken in September 1996. A number of modifications to the basic PCR format have been developed in an attempt to increase amplification efficiency and the specificity of the reaction. The incidence rate in the population served by our hospital is approximately 1-2 cases per 100,000 per year. Goals and methods are illustrated by examples from the assessment (Marschak Interaction Method) and by sessions with a 6 year old regressive noncompliant mutistic twin.

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Before the effort of the Future of Pediatric Education II (FOPE II) Project, very little information existed regarding the characteristics of the pediatric subspecialty workforce. In a case-control study, LA was determined in 176 consecutive outpatients who underwent phlebography because of the first episode of clinically suspected DVT of lower limbs. Intrathecal (IT) pumps have become a valuable tool in managing intractable non-cancer pain. Generalization of fear-motivated interference with water intake.

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This review addresses various aspects of parasitic infections in term of clinical, diagnostic and therapeutic challenges associated with HIV-infection. A reversephase high performance liquid chromatography (RP-HPLC) method for the analysis of the drug in rat plasma was developed and validated as per ICH guidelines. No major complications occurred with surgery nor after a follow-up of 1-3 1/2 years. Point of care computer reminders generally achieve small to modest improvements in provider behaviour.

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In this study, we investigated the upstream kinases that mediate the activation of the 42-kDa MAPK p42mapk/erk2 following crosslinking of CD120a in mouse macrophages. A specific increase in temperature is necessary to achieve a temperature-mediated therapeutic impact by ultrasound in rehabilitation.

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In addition, we evaluated the time required to achieve hemostasis using Tisseel and how much it can influence operative time. Influence of ingesting a solution of branched-chain amino acids on plasma and muscle concentrations of amino acids during prolonged submaximal exercise.

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Inhibitors of antibacterial activity and certain secondary aspects of streptomycin in the organism in tuberculosis Chronic morphine treatment reduces the incidence of ventricular arrhythmias in the isolated rat heart induced by dynorphin1-13 or myocardial ischemia and reperfusion.

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Ultradian rhythms in cognitive performance: no evidence for a 1.5-h rhythm. The purpose of this study was to examine the immunologic cross-reactivity between E.

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Effects of halogenated analogues of cortisol and progesterone upon hair growth in castrated mice. No structural mutation in the coding sequence of the Rb gene was detected.

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Equilibrium properties of realistic random heteropolymers and their relevance for globular and naturally unfolded proteins. We looked for influences of the experimental condition on the silent period (SP) from transcranial motor cortex stimulation and analyzed how the instruction given to the subject, as well as the individual reaction time, might affect the duration of the SP in the biceps brachii muscle. Active sites of nitrogen-doped carbon materials for oxygen reduction reaction clarified using model catalysts. Closing ventricular septal defects in the cardiac catheterization laboratory.

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Its operation was CO(2)-neutral and did not require buffers or exogenous electron transfer shuttles. coli MM52 (SecAts) (a conditional lethal mutant defective in protein translocation) allowing only poor growth at the nonpermissive temperature. The expression was evidenced immunologically in whole cells with polyclonal antibodies raised against the purified oxaloacetate decarboxylase. The course of her ailment is interesting because her treatment is mainly symptomatic. Functional health literacy is associated with health status and health-related knowledge in people living with HIV-AIDS.

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In a triage approach, PCH assistants conduct pre-assessments to identify children requiring follow-up assessments by a physician or nurse. Postoperative pyoderma gangrenosum should be taken into consideration if a sterile, painful, chronically progressive, ulcerative and sludgy defect develops after surgery. A six-degree-of-freedom passive arm with dynamic constraints (PADyC) for cardiac surgery application: preliminary experiments.

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Characterization of cytoplasmic binding of dihydrotestosterone by the prostate gland, seminal vesicles, kidney, and liver of the mouse. Physiopathology of cellular abnormality in nocturnal paroxysmal hemoglobinuria The antibodies have been reported to react also with the chromaffin cells of carcinoid tissue. Previous lower abdominal surgery may be a relative contraindication to the total extraperitoneal approach.

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An intervention with high-risk mothers who abuse alcohol and drugs: the Seattle Advocacy Model. Design and synthesis of isoxazole and isoxazoline linkage for replacement of nucleotide phosphodiester. Quantitative EEG correlates of the human frontal lobe dysfunction

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Diagnostic applications have been proposed in cancer, cardiovascular diseases, kidney diseases, neurological diseases and many more. Eysenck and Cattell factor scores were correlated with scores over homogeneous item groups (FHIDs) which define the Comrey test factors.

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Development and characterization of a porcine model to study osteoclast differentiation and activity. The loss of PTP1B and TC-PTP phosphatase activity is associated with an increase in cytokine sensitivity, elevated JAK-STAT signaling, and changes in gene expression. Like insulin, 2 nM visfatin induced GLUT 4 translocation from the cytosolic fraction to the membrane in 3T3-L1 cells. Some studies have shown a low risk of lymph node metastasis and distant failure whereas others have not, possibly due to differences in the definition of tumor size. Fructose is a major dietary component directly related to vascular dysfunction and diseases such as obesity, diabetes, and hypertension.

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Contribution of the pentose cycle to the metabolism of glucose in the isolated, perfused brain of the monkey. Therefore, the exact contribution of bradykinin to the beneficial effects of ACE inhibition on cardiovascular hypertrophy remains to be further explored.

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Recent studies indicate that PA, and its immediate metabolites diacylglycerol and lyso-PA, affect numerous cellular pathways including ligand-mediated secretion, cytoskeletal reorganisations, respiratory burst, prostaglandin release, cell migration, cytokine release, and mitogenesis. The joint inflammation was passively transferred to normal syngeneic recipient mice with lymphoid cells but not with sera from mice immunized with MT followed by treatment with the anti-IL-4 Ab. Dose response of N-butyl-N-(4-hydroxybutyl)nitrosamine on urinary bladder carcinogenesis in mutant ODS rats lacking L-ascorbic acid synthesizing ability.

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Although there has been tremendous progress on the structure and function of the T3SS substrates, there has been comparatively little progress on the much more highly conserved secretion apparatus itself. Obtained expression data were weighted against clinical and pathology parameters of clinical relevance. Literature on consumption/self-administration and reinstatement of drug seeking as outcomes of interest published up to April 2015 was retrieved via PubMed. We propose that lysosomes are maintained within cells by a repeated series of kiss and run, transient fusion and fission processes with the late endosome/prelysosome compartment. Smooth and sparsely-spined stellate cells in the visual cortex of the rat: a study using a combined Golgi-electron microscopic technique.

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We conclude that this presentation represents a separate form of MCL which requires splenectomy. Urinary kallikrein: a marker of blood pressure sensitivity to salt. To achieve the goals of improving quality of care while managing costs, further efforts are required regarding systematic development and evaluation, consistent implementation and compliance metrics, and transparency in implementation outcomes and financial motivators. The degree of inflammation decreased and the maturity of fibrous tissue formed at the enteropexy sites increased for all specimens over time.

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This lack of influence was shown consistently by all tests of the present meta-analysis. CanL was diagnosed using cytology in one case and indirect immunofluorescence assay and conventional polymerase chain reaction in the second. The ongoing growth of defined contribution and individual account plans: issues and implications.

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Optical and FDG mapping of frequency-specific activity in auditory cortex. Measurements of the abundance of common metabolites in cultured embryonic stem (ES) cells revealed an unusual state with respect to one-carbon metabolism. Previously reported cases of uterine leiomyoma in the mare have been of solitary tumors in older mares that were treated successfully by surgical removal. Visual attention mechanisms show a center-surround organization. The role of AVP in hypertension remains controversial, but recent evidence suggests that a discordance between the various central and peripheral cardiovascular actions of AVP, rather than its hormonal vasopressor effects, may contribute to the pathogenesis of hypertension.

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The methods are applied to the paramagnetic High-Potential Iron-Sulfur Protein iso I (HiPIP I) from E. Results suggest that thermal stress increases susceptibility of intestinal epithelial Caco-2 cells to Salmonella adhesion, and increases the cytotoxic effect of Salmonella during infection.

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Long-term outcome of kidneys with initially poor drainage or no drainage following pyeloplasty. The available evidence indicates that phototoxic components of oil are specific 3-5 ring polycyclic aromatic hydrocarbons (PAHs) and heterocycles. Regression analysis, using random effects linear models, showed that only C-reactive protein, alpha 1-acid glycoprotein, iron, and erythrocyte sedimentation rate were significantly, but not independently, associated with 6 month radiographic progression.

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Programmed electrical stimulation, also known as electrophysiologic studies (EPS), is a cardiologic technique used to help guide physicians in their management of selected patients with cardiac arrhythmias. Neoadjuvant chemotherapy combined with regional hyperthermia (RHT) for locally advanced primary or recurrent high-risk adult soft-tissue sarcomas (STS) of adults: long-term results of a phase II study. Healthy adult males (aged 21 to 55 years) were randomly assigned to receive single oral doses of ABT-639, pregabalin, and placebo. Supplementation of human vessels and blood with BH4 ex vivo revealed rapid oxidation of BH4 to BH2 with predominant BH2 uptake by vascular tissue. The purpose of this article is to highlight the significance of the work environment in academic settings in terms of human needs theory and to offer suggestions for creating and maintaining a healthy academic work environment.

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Finding preventative measures could be facilitated by a molecular-level understanding of dimer formation, which is the first step in aggregation. The role of screening for Helicobacter pylori in patients with duodenal ulceration in the primary health care setting. Identification, using cDNA macroarray analysis, of distinct gene expression profiles associated with pathological and virological features of hepatocellular carcinoma. Association of interrupted aortic arch with malformations producing reduced blood flow to the fourth aortic arches. The women were treated in two different cancer treatment programs: complementary treatment, which included anthroposophic therapy, and conventional cancer treatment.

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The activity of the betagamma dimers was compared in two assays: formation of the high affinity agonist binding conformation of the A1 adenosine receptor and receptor-catalyzed exchange of GDP for GTP on the alpha subunit. To characterize more precisely the role of MIF in the host response to infection, we undertook a systematic analysis of MIF expression in various organs of the rat after endotoxin (lipopolysaccharide) administration. No significant change was found for aldehyde reductase activity. A number of observations in vivo and in vitro indicate that inflammatory mediators contribute to this process. The higher-molecular-mass group was found in follicular thyroid cancer tissues which and was not visible in normal thyroid tissues.

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Reduction of household density is an attainable intervention that could reduce the prevalence of skin disease in rural African populations. Androgen receptor gene analysis showed an increased number of tandem CAG repeats in exon 1, thus leading to a diagnosis of Kennedy-Alter-Sung (KAS) syndrome. We have recently generated transgenic mice expressing a chimeric LH beta subunit (LH beta) in gonadotropes. Median survival was 90.3 months, with a range of 14 months to 13 years.

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Carbopol 934 and NaCMC were used as bioadhesive polymers and Methocel K4M, Methocel K15M, and HPC were added as matrix-forming polymers. Amino acid sequences common to rapidly degraded proteins: the PEST hypothesis. The results indicated that Ct MOMP multi-epitope delivered by HBcAg could be an effective vaccine for the prevention of Ct.

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A series of clonal cell lines were derived from rat liver epithelial cells after being infected with a defective retrovirus containing either v-raf (3611-MSV) or v-raf/v-myc(J2) together with a helper virus. The platysma myocutaneous island flap has demonstrated high versatility and reliability when used to close defects in the oral cavity in a series of ten patients. Moreover, we used cDNA expression arrays to evaluate the biological influence of CXCL12alpha. Lack of effect of acupuncture upon signs and symptoms of delayed onset muscle soreness.

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An HPV assay based on PCR amplification of a region of the E6 open reading frame and ELISA detection of PCR products that specifically identify high-oncogenic-risk HPV types (eg, types 16, 18, 31, 33, 35, 39, 45, 56, 58, and 65) was developed. Ribonuclease protection assays reveal that RNAs coding for all three FGF-8 isoforms are present at days 10-12 of gestation. Characterization of the gene for human plasminogen, a key proenzyme in the fibrinolytic system.