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Two native glucuronan samples with various degrees of acetylation were sonicated to obtain lower molecular weight samples and with low viscosity suitable for chemical modification and (13)C NMR experiments. Ultrasound-guided fine-needle aspirates of the mesenteric lymph nodes were highly suggestive of lymphoma. Further, addition of ammonium salts to nitrogen-starved cells was sufficient to rapidly reactivate HAC1 splicing.

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Self-assembly of a metal-ion-bound monolayer of trigonal connectors on mercury: an electrochemical Langmuir trough. Costimulation regulates the kinetics of interleukin-2 response to bacterial superantigens. The oxidation of carbohydrates (CHO-ox) was increased in both cases.

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The aim of this work was (i) to determine the thermal resistance of P. Momentum for strong workplace advocacy structure within ANA continues. For the dietician-led group, a standard protocol of six postoperative visits and two to three fluoroscopic adjustments was developed from referral until 2 years after surgery.

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Physicians need to be aware of this potentially fatal drug effect and should monitor EKGs of patients on lithium. Furthermore, both sensitive MCF7/WT and mitoxantrone-resistant MCF7/MX cells contain equal amounts of DNA topoisomerase I protein, and DNA relaxation activities were equal in both cell lines and inhibited to the same extent by topotecan and camptothecin. In the absence of infection or neoplasm, such lesions are then designated as ulcers not otherwise specified. Mouse forces were measured from 16 subjects (8 men, 8 women), on 3 separate days, at their actual workstations while they performed (i) their regular work, (ii) a battery of standardized tasks, and (iii) simulated mouse use. We developed a novel technique for endoscopic aspiration lumpectomy and used it in patients with esophageal leiomyomas derived from the muscularis mucosae.

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This method is useful in assessing biocompatibility of various hollow fibers in a simple and safe manner. These results may have important implications for efficacy considerations when adenoviral vectors are used for clinical cancer gene therapy. Hypothalamic and noradrenergic mechanisms for control of pain sensitivity are discussed. However, conventional magnetic resonance imaging (MRI) cannot differentiate between vasogenic and cytotoxic edema. Physiological factors associated with efficiency in high intensity exercise.

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An axial column (3 x 2.6 cm) and a radial flow column (3.5 x 5 cm) packed with DEAE Sepharose Fast Flow media was evaluated for the separation of human prothrombin from Nitschmann fraction III. Tuberculosis is an uncommon cause of acute respiratory distress syndrome even in high tuberculosis prevalence countries.

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It was also shown that large numbers of dead cells have little effect on growth rate and that these dead cells last as discrete entities for many days. To identify variables associated with mortality in the ICU and 1 year following discharge.

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This study indicates that a substantial number of Black women suffer from significant symptoms of depression and report that they have been diagnosed with depressive disorders in their lifetime. Coronary angiographic studies revealed a linear dissection involving the proximal and mid segments of the right coronary artery. In the control mice the relative inhibition of insulin release and glucose oxidation rate was similar at 4 and 8 weeks. The aims of this study were to evaluate whether the risk allele of TCF7L2 gene polymorphism is associated with dyslipidemia and MetSyn. Plasma clearance of nonradioactive iodine contrast media (i.e., iohexol or iopromide) has been suggested as a reliable alternative to the renal clearance of inulin for estimating glomerular filtration rate (GFR).

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The Italian Multicenter Project for Propranolol in Prevention of Bleeding. In this study we used a rat model of single lung transplantation to show that ischemic preconditioning also occurs in the lung.

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Collateral reinnervation from the uninjured nerve was limited to the border innervation area of the palm and ring finger. Employment Outcome Ten Years after Moderate to Severe Traumatic Brain Injury: A Prospective Cohort Study. In myelinated axons, tubular structures measuring 20-50 nm in diameter contained ACPase reaction products. This finding is consistent with the effects of this drug on social aggression in mammals and birds and supplements previous reports that 5-hydroxytryptamine inhibits aggression in fish.

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The condition arises from paresis of the muscles that control the foot movement during the swing phase of gait. Using promoter-specific IGF-I RNA probes, we detected only promoter 1 transcripts in all fetal tissues examined. Adolescent substance abuse remains a public health problem, and more effective treatment approaches are needed. Synthesis and field evaluation of methyl-branched ketones, sex pheromone components produced by Lithosiinae female moths in the family of Arctiidae. Increased lipid peroxidation and antioxidant activity in methionine-induced hepatitis in rabbits.

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The prevalence of ossification variants of the unaffected femoral condyle in 116 patients (aged 9-14 years) with unicondylar OCD on MRI (magnetic resonance imaging) of the knee was compared to a control group of 579 patients (aged 9-14 years) without OCD. globiformis was present in the hydrocarbon-oxidizing bacteriocenosis throughout the whole period of the succession. T-box genes constitute a conserved multi-gene family with important roles in many developmental processes. With the use of portable equipment and submaximal testing the scope for future research in numerous populations and non-laboratory environments is considerably increased.

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Prolonged hypokinesia caused cardiac deadaptation in rabbits which resulted in diminishing of the left ventricle speed of contraction and relaxation joined later by a decreased vascular resistance. Among rat intestinal glycosidases, only trehalase was potently inhibited by calystegine B4, with an IC50 value of 9.8 microM. The case against the conservative nonresectional management of infected prosthetic grafts. A uniform dosage of 2 mg/kg/day in two divided doses was administered subcutaneously for 10 days during hospitalization and then continued on an out-patient basis. Together these data suggest that other cellular factors likely play a role in overcoming the inhibitory effects of ionizing radiation on p53 in drug-resistant breast cancer cells.

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A surfactant-free synthesis of mesoporous and hollow silica nanoparticles is reported in which boron acts as the templating agent. An experimental study of the vesical circulation during distension and in cystitis. We studied binding of RXR- and RAR-selective ligands to the RXR-RAR heterodimer and subsequent transcription. To find out the exposures with biological material in health care workers in primary health care, registered in the biological accidents database from Preventive Medicine Service in Miguel Servet Universitary Hospital of Zaragoza.

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Thus, CAP1 plays a key role in speeding up the turnover of actin filaments by effectively recycling cofilin and actin and through its effect on both ends of actin filament. These parameters include the filtration fraction, renal blood transit time and urine transit times. Mutant frequency in the lacZ gene of the pUR288 plasmid was determined in DNA isolated from spleen (target) and kidney (nontarget) tissues.

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Risk factors among men who have repeated experience of being the partner of a woman who requests an induced abortion. Verapamil was found in high concentrations in the mucosa, less in the adventitia, and was absent in venous blood. They think there is a recessive gene on an autosome and a gene on the inhibiting chromosome X.

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Symptomatic tachycardia is a common admission diagnosis in the emergency department (ED). The lesion was surgically excised by blunt dissection using a posterior midline approach. The most interesting member of the series, 6-chloro-2(1-piperazinyl)pyrazine (3a), had pharmacological properties characteristic of potent central serotoninmimetic activity and only weak peripheral serotoninmimetic action.

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Comparative study of ureteral anastomosis with or without double-J catheterization in renal transplantation Assumptions about the usefulness of mailed surveys versus telephone interviews may not hold for the urban poor. The adverse drug events associated with LUTS-causing drugs were highly prevalent in elderly patients.

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Effects of amphetamine analogs on neurotensin concentrations in rat brain. Reduction in circulating leukocyte and platelet counts was evident after two weeks of therapy. This finding has important clinical implications in the assessment and treatment of dysphagic individuals. We believe that endoscopic thyroidectomy and parathyroidectomy by the axillary approach will find a role in the treatment of endocrine diseases in the neck.

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NaCl taste thresholds measured in this study did not significantly correlate with NaCl preferences or amiloride sensitivity of chorda tympani nerve responses to NaCl determined in the same strains in other studies. Alternatives include inhibition of DNA topoisomerase II activity, regulation of cell cycle checkpoints, and antiangiogenic and antioxidant activity. The equations that have been used previously to analyse the rate of decay of hnRNA implicitly assume that nascent hnRNAs are degraded stochastically. Tat is unique among transcriptional activators in acting through an RNA target, the TAR element. Early research efforts using patient derived CRC samples led to the discovery of several highly penetrant mutations (e.g., APC, KRAS, MMR genes) in both hereditary and sporadic CRC tumors.

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Anticoccidial drugs: factors affecting pathogenicity of avian coccidia. Zona pellucida 3 (ZP3) is a major glycoprotein of the zona pellucida that possesses the sperm receptor function.

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Selective recall and memory distortion of favorable and unfavorable material. The problems of scattering by both a sphere and a cylinder are canonical problems in optics. To help elucidate this issue, this paper first deals with a quantitative investigation of aluminum-phosphate equilibria under physiological conditions. Randomized trials comparing low-molecular-weight heparin administered at different times relative to surgery with oral anticoagulants in patients undergoing elective hip arthroplasty, evaluated using contrast phlebography, were selected.

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Male differentiation is initiated by fetal testicular androgen synthesis, catalyzed by the enzyme 17alpha-hydroxylase/17,20 lyase cytochrome P450 (P450c17). However, when the injury was repeated, the number of labeled motoneurons was reduced, suggesting that a significant proportion had died. Having rejected other possible causes that can favor the appearance of basal cell carcinoma during childhood (basal cell nevus syndrome, nevus sebaceus, albinism, etc.), we believe that this case should be added to the five previously reported in the literature as basal cell carcinoma developing at an early age in cranial radiation portals with megavoltage radiotherapy. In theory, birds should control the sex ratio of the offspring they produce. The relationship between the occurrence of palsy and different preoperative radiological information is analyzed.

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The purpose of this study was to compare the tube agglutination DAT to gel microcolumn, affinity microcolumn, and flow cytometric DATs on RBCs coated in vitro and on patient RBC samples. Using a sterile technique and real-time Doppler ultrasound guidance, a dilute solution of bovine thrombin (average dose 250 units, range 100-600), was slowly injected directly into the pseudoaneurysm until cessation of flow was seen.

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Loss of fibulin-4 during embryogenesis results in perinatal lethality because of aneurysm rupture, and defective elastic fiber assembly has been proposed as an underlying cause for the aneurysm phenotype. P300 latencies increased, and P300 amplitudes decreased with extended wakefulness. In primary lymphoma, most lesions were in the periventricular areas, appearing as multiple large well-defined margin masses with minimal surrounding edema and dense homogeneous enhancement on both CT and MR studies.

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PTSD was highly comorbid with depressive disorders and associated with post-spinal cord injuries within the previous year. We reviewed urological complications: stenosis, fistula and obstruction. Activities of the pediatric consultants of the National Organization of Maternal and Infant Welfare of the Province of Siena in 1948-52

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The relative contribution of demographic, lifestyle and medication factors to the association between affective disorders and cardiometabolic diseases is poorly understood. Moreover, the healing recovery was evaluated by visual observation of infected dorsal wounds on rats with induction of diabetes by streptozotocin. These nerve conduction parameters may be affected by anthropometric factors like age, sex, height, weight and BMI. Through comparative analysis of morpholino oligonucleotide induced knockdown of dkc1 and a retrovirus insertion induced mutation of GAR1/nola1 in zebrafish, we demonstrate that hematopoietic defects are specifically recapitulated in these models and that these defects are significantly reduced in a p53 null mutant background. Understanding of the regulation machinery is beginning to emerge and promises much excitement in discovery.

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Effective utilization of forms for efficient office communication. In order to test these drugs, an ocular model of adenovirus infection was developed in 10 Hollander rabbits following topical, intrastromal and subconjunctival inoculation with a standard laboratory serotype (Adenovirus type 5 from The American Type Culture Collection). A sensitive and selective high-performance liquid chromatographic method with native detection of fluorescence was developed and validated for the quantitation of ivabradine and its N-demethylated metabolite in plasma (rat, dog, human) and human urine. In this paper we define prospective ergonomics and compare it with corrective ergonomics and ergonomics for design. However, whether other KLK family members play a role in regulating cardiac function remains unknown.

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Sedatives/minor tranquilizers were most often prescribed to DIS-positive women. In this report, we characterized the virulence of strains from which the plasminogen activating protease (pla)-encoding pPCP1 plasmid was cured from either the wild-type (WT) or the Deltalpp mutant strain of Y.