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Comorbid subjects had a tendency to belong to multiply affected families and show high rates of chromosomal variants on routine karyotypic testing. The high affinity streptavidin (or avidin)/biotin system is being investigated for imaging and radiotherapy procedures. Up to now, azathioprine had been held responsible for peliosis hepatis only in renal transplant recipients. Expression of alpha-bungarotoxin receptor subtypes in chick central nervous system during development. HIV-2-specific antisera recognized both the chimeric and parental virus but not HIV-1MN.

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The p53 mutation status was analyzed by direct sequencing of the PCR product in highly conserved exons 5-8. Reflex gastric relaxation in response to distention of the duodenum. The iterative two-stage population approach to IVGTT minimal modeling: improved precision with reduced sampling.

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To obtain larger amounts of protein free from possible unknown plasma contaminants, human alpha 1-PI has been produced by recombinant DNA. To compile curves for growth in weight and height for Italian children and adolescents. At the Department of Radiotherapy, University College Hospital (UCH), Ibadan, Nigeria, intracavitary brachytherapy (ICBT) was delivered by a GyneSource high-dose-rate (HDR) unit with (60)Co. Isolated bilateral neurofibromas of the brachial plexus in neurofibromatosis type 1. This represented an annual rate 220 times the North American average.

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The effect of hetastarch on serum colloid oncotic pressure in hypoalbuminemic dogs. Preimaginal body cultures may be maintained for 2 to 8 months or longer and hemocyte cultures for 1 to 9 months.

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We demonstrate that the physiological cytokines, macrophage colony-stimulating factor and granulocyte colony-stimulating factor, can instruct hematopoietic lineage choice. Here, using in vitro binding assays, we examined the relationship between the number of repeats in a TALE and its affinity, for both target and non-target DNA. Cone beam CT (CBCT) is an emerging X-ray technology applied in dentomaxillofacial imaging. A report on the 11th Annual Congress of the German Society for Implantology in Dentistry, Oral Medicine and Orthodontics, Inc. Severe infections in children with sickle cell disease: clinical aspects and prevention

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These findings strengthen the evidence for involvement of the Notch, Hedgehog, NF-KB, and PIK3CA pathways in breast cancer development, and point to novel processes that likely are involved. In clinical applications, such as PhotoDynamic Therapy, direct singlet-oxygen detection through its luminescence in the near-infrared range (1270 nm) has been a challenging task due to its low emission probability and the lack of suitable single-photon detectors. This information is valuable for early detection of osteoporosis on low-dose chest CT. Tumor necrosis factor (TNF)-alpha dosage was made on culture supernatants.

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The diagnosis of louse-borne relapsing fever is commonly made on the basis of the detection of Borrelia spirochetes on Giemsa-stained thin blood films. Some physicochemical properties of native isozymes and of similar isozymes generated in vitro. Prognostic significance of microvascular invasion in localized renal cell carcinoma. Post-insult failure of regeneration leads to various incurable lung diseases including chronic obstructive pulmonary disease (COPD) and idiopathic pulmonary fibrosis.

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Parasitic infections--molecular diagnosis and rational drug design. Furthermore, ATC application rescues osteogenic differentiation of hMSCs in culture conditions that are intrinsically repressive for hMSC osteogenesis (e.g., soft cell culture surfaces). Isolation guidelines for patients with severe GAS infection may need to be reviewed. These may form the basis of an alert to hypoglycaemic levels or ultimately be connected directly to continuous insulin infusion, particularly with rapid-acting insulin analogues, to maintain glucose within normal physiological limits. Entry of bovine viral diarrhea virus into ovine cells occurs through clathrin-dependent endocytosis and low pH-dependent fusion.

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Astrocytes were isolated from cerebral cortex of SD rats born in 24 hours, and then cultured and purified. This work contributes to our understanding of GSLE activation and function during germination. This technique is simple and quick, and can produce progressive thrombosis in these high-flow vascular fistulas.

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We suggest that spatial autocorrelation must be studied to explore the spatial structure underlying morphological variation and incorporated in regression models to provide more accurate statistical estimates of the relationships between morphological and ecological variables. Splenic artery aneurysms are uncommon even though they are second only to those of the aorto-iliac system. How long does the protective effect on eccentric exercise-induced muscle damage last?

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The palinopsia was dose related and disappeared with reduction or cessation of therapy. The percutaneous approach to the subclavian vein or internal jugular vein was considered a last resort to implant a catheter.

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Auricular defects occur from a variety of different causes and a wide array of reconstructive options are often necessary. The magnitude of this effect was greatest when combined with the low-difficulty problems. Coagulation factor concentrates and point-of-care coagulation monitoring: both might be essential for optimal treatment of trauma-induced coagulopathy.

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The perilymph space of the guinea pigs cochlea was perfused with artificial perilymph solution containing 1 microgram/microliter SP receptor antagonist (D-Arg1, D-Pro2, D-Trp7,9, Leu11)-SP (1-11) at a rate of 2.5 microliters/min for 10 min while monitoring cochlear potentials evoked by 4 kHz tone burst. Results of a questionnaire regarding the practice of radiotherapy for carcinoma of the cervix in the UK.

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Effector areas for specific thermoregulatory responses are located throughout the brain stem and spinal cord. The pi- and mu-classes were both identified by their respective specific substrates, and after reverse-phase HPLC, by N-terminal analysis of 19-35 of the amino acids. Doxorubicin reduces the iron(III) complexes of the hydrolysis products of the antioxidant cardioprotective agent dexrazoxane (ICRF-187) and produces hydroxyl radicals. Study of the LCR at the brainstem level could provide insights into normal maturation of respiratory centers and eventually the pathophysiology of these disorders. This case report highlights the cytological features that can be useful in clinching the diagnosis of sarcoidosis in conjunction with clinicoradiological and laboratory findings in a clinically unusual case.

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The transgenic plants exhibited a short-hypocotyl phenotype under blue, UV-A, and green light, whereas they showed no difference from the wild-type plant under red/far-red light or in the dark. Inhibition of caspase-mediated cleavage of these proteins protected against detachment but not opening of the paracellular pathway. Here, we define two novel translation products from the SIV env mRNA that are targeted by the T-cell response in SIV-infected rhesus macaques.

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Potentially mortal, sometimes can be entirely removed by surgery, with complete recovery. Certain situational factors may be used to predict the risk of encountering violence. The pathological interaction between quartz and interstitial macrophages may lead to quartz particles being sequestered in silicotic nodules, and also cleared to the efferent lymph nodes. This reappraisal is now possible due to the conditional acceptance of harmonised guidelines on toxicokinetics at ICH2 in Orlando in 1993, the results from which can provide much of the information that is required to design and validate safety studies and to extrapolate exposure or safety margins to man. The resulting proportions of cases identified, demographic characteristics, service use, and perceived need for services were compared.

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On the contrary, transcatheter atherectomy achieves atherosclerotic plaque clearance by means of directional plaque excision or rotational plaque removal or laser plaque ablation. The carbohydrate-recognition domain of RHL-2/3 has been prepared by limited proteolysis of the liver receptor so that its properties can be compared with those of the corresponding domain of RHL-1 previously produced in a bacterial expression system.

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In view of the high percentage of patients with vascular injury, first rib fracture in a pediatric patient should prompt a search for major vascular injury. A Tropherine-added regimen can be effective in hyperopic children, with less associated discomfort than the instillation of cyclopentolate. Recombinant interferon alfa in the treatment of chronic hepatitis C The control group was applied with distilled water that is equal in quantity.

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Oppositely, the addition of acetone in the inhalation protocol using o-xylene lead to a lower ethoxyresorufin deethylation activity as that in rat livers from rats pretreated with xylene alone. These findings suggest that mortality rates are sensitive to even minor differences in social and cultural factors across countries and over short time periods.

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Knockdown of PFTK1 inhibits tumor cell proliferation, invasion and epithelial-to-mesenchymal transition in pancreatic cancer. Isolated human islets require hyperoxia to maintain islet mass, metabolism, and function.

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Effects of different concentrations of sevoflurane and desflurane on subcortical somatosensory evoked responses in anaesthetized, non-stimulated patients. Interestingly, hypsodonty-related changes influenced the tooth row in artiodactyls and perissodactyls significantly but in the opposite directions, which is ultimately related to their different digestive strategies. Accuracies provided by the manufacturers usually overestimate the accuracy provided by academia.

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These data indicate that generation of O(2)(-) in BPASMCs in response to 5-HT is followed by an increase in intracellular H(2)O(2) that mediates 5-HT-induced mitogenesis through activation of ERK1/ERK2 but not of p38 MAP kinase. In the first phase we identified the number of shared care schemes for chronic disease, which were followed up in the second phase. A serum- and feeder-free technique of culturing human corneal epithelial stem cells on amniotic membrane. Analysis of the dynamics of fungal communities in soil via fungal-specific PCR of soil DNA followed by denaturing gradient gel electrophoresis.

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These included fixation with a combination of glutaraldehyde and paraformaldehyde, followed by postfixation with osmium tetroxide and lead citrate and embedding in Epon. Collateral status using relative filling time delay (rFTD) determined by time delay of collateral-derived contrast opacification within the Sylvian fissure, from 0 seconds to unlimited count. Echo cardiography and cineangiography revealed the truncal valve to be bicuspid, and the regurgitation severe, especially through the prolapsed left sided cusp. Merkel cell carcinoma: value of sentinel lymph-node status and adjuvant radiation therapy. A plea is made to publicise this in health education programmes and in media as a measure for early detection of breast cancer.

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TE7 ms matched with CT for demonstrating the extent of bronchiectasis whereas TE30 ms scans were inferior to CT. Complex multiple interactions between cells and the extracellular matrix occur during acinar morphogenesis and changes in these might indicate carcinogenesis of cells from a normal to a malignant, invasive phenotype. The scores of the SDS and Apathy Scale showed significant negative correlations with the scores of most of subscales of the SF36.

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Data on resource use cover the 6-month period prior to this time point. Persistent mullerian duct syndrome with an irreducible inguinal hernia. Ultra acidic strong cation exchange enabling the efficient enrichment of basic phosphopeptides. The binding of freshly isolated monocytes from patients with NIDDM, IDDM, and healthy control subjects to a monolayer of endothelial cells obtained from human umbilical vein was investigated.

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In addition, when tyrosine phosphorylation induced by HHV-6 infection was inhibited by the tyrosine kinase inhibitor biochanin A, the infection of HSB-2 cells was also coordinately reduced, as judged by inhibition of cytopathic effect and by inhibition of early and late viral antigen expression. Assessment of a low-cost home monitoring spirometer for children. Cocoa polyphenols attenuate hydrogen peroxide-induced inhibition of gap-junction intercellular communication by blocking phosphorylation of connexin 43 via the MEK/ERK signaling pathway. Understanding how non-viral vectors initiate gene expression could lead to the development of new future vectors with enhanced efficacy.

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These synthetic peptides are selected to correspond to fragments of the protein that can be obtained by proteolytic treatment of the protein by trypsin. The aim of this study was to assess and compare the dietary intake, leisure-time physical activity (LTPA), and biochemical measurements (glucose, A1C, and plasma lipids) in women with FPLD2 and without (control group, CG) and to examine the associations between dietary intake and biochemical measurements (BM). Objective To determine whether a tilting system located in the seat of a chair allows for performing voluntary macro-repositioning movements of the pelvis in order to reduce the perception of pain after a prolonged period in the sitting posture. Precisely where these tumors originate remains a topic of controversy.

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In situ labeling studies revealed a significant increase in the number of apoptotic cells within GALT from macaques with acute SIVsmmPBj14 infection, compared to (i) other tissues from the same animals, (ii) GALT from virus-negative animals, or (iii) GALT from macaques that were sacrificed soon after infection with SIVmac239, which does not cause acutely lethal enteropathy. During the past decade, rates of severe complications after PPV remained stable, but rates of less severe complications and subsequent operations increased.

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Serotonin transporter overexpression is responsible for pulmonary artery smooth muscle hyperplasia in primary pulmonary hypertension. Ultrasonography of the specimen showed a nodule with mixed echogenicity surrounded by a hypoechoic rim. Posttranslational modifications, such as glycosylation, acetylation, S-nitrosylation, and phosphorylation, are known to induce protein conformational changes.

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Power frequency magnetic field exposures among nurses in a neonatal intensive care unit and a normal newborn nursery. The results indicated that incubation of cholesterol and LPS showed less synaptic connections, neurite outgrowth and cell shrinkage as compared to normal cerebellar cells. Electron microscopy demonstrates that axons from about 115 neurosecretory cell bodies in the Xo form the Xo-sg tract. Progressive renal interstitial fibrosis occurs following tissue injury, resulting in chronic renal failure. The R(t) function oscillates with the same cycle length as the birth function, but it is not sinusoidal and its asymmetry increase as the amplitude of birth function increases.

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The purpose of this study was to evaluate the safety and efficacy of endoscopic axillary lymphadenectomy using needlescopic instruments in patients with breast cancer. Detection, prevention and treatment of postpartum depression: a controlled study of 859 patients This study suggests that the sporulation process is mediated by a regulatory protein which is altered in the thermosensitive mutant when grown at the restrictive temperature. Acute, subchronic, and chronic toxicity studies with felbamate, 2-phenyl-1,3-propanediol dicarbamate.

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The consumption of nutrients by rodents is markedly influenced by the number of containers of each nutrient provided. IgE antibodies to Fel d 1 and albumin do not fully account for IgE responses to cat and there is good immunochemical evidence that cats produce other allergens. Gruppo Italiano per la Valutazione degli interventi in Terapia Intensiva.

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Bioequivalence of a generic preparation of oral zidovudine in healthy Thai volunteers. Interobserver reliability was highest between plastic surgeons for the subitem and overall scores and ranged between 0.56 and 0.82. GFP-fused SpPdi2p and SpPdi3p were found to localize to the endoplasmic reticulum. Isolation-reared rats showed an increased frequency and decreased duration of contact behavior. Transcatheter microcoil embolotherapy for ruptured pseudoaneurysm following pancreatic and biliary surgery.

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In the two other patients splenectomy was performed in the recompensated stage, one month and five years, respectively, after the primary induction had been concluded. We selected sertraline as a model SSRI for a 28-d study with adult male fathead minnows. Selective quantitative analysis of the intensity of immunohistochemical reactions. Long-term results of Taiwan Pediatric Oncology Group studies 1997 and 2002 for childhood acute lymphoblastic leukemia.

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3-MT levels were markedly reduced by both, implying that DI does not alter the portion of dopamine release mediated by neuronal impulse flow. The hazard of vacuuming spilled mercury and appropriate clean-up procedures are described. We conclude that tautomerism is essential to the comprehension of the chemical behavior of tetracycline as determined by the semiempirical method AM1 as well as by the self-consistent reaction field method, which estimates the effects of the solvent on the tautomers. Here, we show that hydroxymethylcytosine preferentially marks polyadenylated RNAs and is deposited by Tet in Drosophila. Indicators of socioeconomic status, including education and white/blue collar occupation based on lifetime occupations were analysed as indicators of risk factors for lung cancer development, after adjustment for tobacco smoking and exposure to occupational carcinogens.

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Benign mesothelial tumors of the urinary bladder: review of literature and a report of a case of leiomyoma. While the mRNAs of prostatic proteins became almost completely absent in the VP, the reductions in the other lobes were limited. Scanning electron microscopy of intervillous connections in the mature human placenta. Enhanced adrenergic constriction of iliac artery with removal of endothelium in conscious dogs. The use of various metabolic inhibitors indicated that ferrous iron transport at pH 5 at both high and low iron concentrations was mediated by transport-type ATPase.

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Neutralizing effect of gamma globulin against Poliomyelitis virus type 2 Toward better compliance with iron-folic acid supplements: understanding the behavior of poor urban pregnant women through ethnographic decision models in Vadodara, India. Cytoxicity experiments demonstrated that ME was not cytotoxic for L929 and HepG2 cells at concentrations less than or equal to of 15 mg/mL.