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It is localized within 2.05 Mb of region q21 on human chromosome 1. We present the case of a 2-year-old boy with progressive left-sided weakness and a cranial magnetic resonance imaging (MRI) scan showing a lesion with a cystic component in the right thalamus and basal ganglia. An immunohistochemical analysis of medulloblastoma and PNET with emphasis on N-myc protein expression.

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Although a number of studies have evaluated the effectiveness of computerized decision-support systems (CDSS), there is lack of data on user perspectives, barriers, and facilitators to the implementation of CDSSs in real-life surroundings. We examined 13 patients with HCC (29 extrahepatic metastases and 3 benign bone lesions) and 5 patients with other cancers (15 extrahepatic metastases). This prospective study aimed to determine the extent to which cancer patients experience loss of dignity during primary cancer care (baseline) and at 3-month follow-up and the contribution of positive social support and detrimental social interactions on loss of dignity at follow-up. Only occasionally we could see few Fos-immunoreactive (Fos-IR) neurons in the medial and superior lateral PB subnuclei. Plasma levels of inflammatory markers (neopterin, kynurenine:tryptophan ratio, and C-reactive protein), anthranilic acid, and 3-hydroxykynurenine were positively associated with all-cause mortality, and tryptophan and xanthurenic acid were inversely associated.

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The present study has demonstrated, however, that intraperitoneal (i.p.) injection of p-chloroamphetamine (PCA), an indirect serotonin (5-HT) agonist, elicited simultaneously both penile erection and ejaculation in anesthetized rats. Confocal laser scanning microscopy demonstrated that the fragmented DNA in the CA1 pyramidal layer was phagocytosed by microglial cells. Arthroscopic BIFT for the LHB showed better improvement in EFSI than arthroscopic STT. Corneal inflammatory LG and HG were induced in two most commonly used mouse strains, BALB/c and C57BL/6 (6-8 weeks of age), by a standardized two-suture placement model.

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Correlation of placental pathology and perinatal outcomes with Hemoglobin A1c in early pregnancy in gravidas with pregestational diabetes mellitus. Measuring and managing user attitudes toward various aspects of computer systems is an important part of making those systems effective.

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Locally produced eicosanoids and endothelium-derived factors are believed to be the mediators of vascular tone of various vascular beds including the mesentery. P/CAF-mediated acetylation regulates the function of the basic helix-loop-helix transcription factor TAL1/SCL.

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Approximately sixty thousand people were enrolled for fever surveillance for 19 months prior to, and 24 months following, Vi vaccination of one third of the study population (May 2003-December 2006, vaccinations given December 2004). Do street food vendors sell a sufficient variety of foods for a healthful diet?

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The short chain fatty acid (SCFA) butyrate provides energy for colonocytes, stimulates colonic fluid and electrolyte absorption and is recognised as an effective treatment for multiple types of colitis. We searched the Cochrane Library, MEDLINE, EMBASE, and Chinese Biomedical Literature Database.

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Structural basis for activation of human lymphocyte kinase Lck upon tyrosine phosphorylation. Furthermore, the points of action of BFA and low temperature appear to overlap since their sequential application reversibly prevents Pr86 processing. Although the effect of the intervention on sexual risk behavior was significantly reduced when the variables were controlled statistically, supporting the hypothesis of their mediation of the intervention effect, most of the effect remained unexplained, indicating the influence of unmeasured factors on outcome.

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Lithium is the most widely recommended drug for this purpose, having been shown in controlled clinical trials to be more effective than placebo in reducing the likelihood of relapse. A total of 37 patients (aged 7-72 months, mean 17.5 months) underwent repair by three pediatric urologists at two institutions. alpha-MSH, i.e., an acute rise in cellular fluorescence intensity as determined by microfluorimetry, was not yet detected at day 4 but present at day 8. To evaluate school entry immunization certificates and document the immunization status of children enrolled during 1994 in kindergartens on the NSW Central Coast. Cigarette smoking is a risk factor for stroke, but the mechanisms by which smoking contributes to stroke are not well understood.

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No significant difference was observed in the cumulative mortality rates from neuroblastoma in children younger than 5 years of age between the screened children and the unscreened children. Use of 123I-IMP brain SPET to predict outcome following STA-MCA bypass surgery: cerebral blood flow but not vasoreactivity is a predictive parameter.

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Mistakes and traps in radiodiagnosis of intestinal obstruction caused by colic stenosis The pathophysiology and optimal treatment of postamputation pain states are unclear. The 2005 Lebanon GHPSS includes nationally representative estimates of third-year students in all dental, medical, nursing, and pharmacy schools in Lebanon. We also aimed to determine the production level of various hematopoietic growth factors in treated patients. We anticipate that publicly available web applications, such as ImmunoMembrane, will accelerate the adoption of automated image analysis in clinical diagnostics of HER2 IHC.

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Both had a profound loss of proprioception and generalized areflexia. This study supports the contention that sedation is unlikely to be the mechanism by which anticholinergic drugs exert their amnestic effect. Influence of sex steroid hormones on rat growth hormone-releasing factor and somatostatin in dispersed pituitary cells. Insulin mitigates the effect of free fatty acid to cause endothelial dysfunction in rat aortic rings Expression of the transgene was associated with marked suppression of the normal pattern of mammary ductal tree development in female transgenics from all three lines.

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Entrapping efficiency of an oil-in-water emulsion containing isocarbacyclin methyl ester (TEI-9090) in dog and human sera. In this moving environment, attention has been placed on a better understanding of the conditions of human reproduction. These substitutions can lead to a null phenotype and enhanced susceptibility to infection by poorly pathogenic mycobacteria, a disorder known as Mendelian Susceptibility to Mycobacterial Disease (MSMD).

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In some cases, increased phase errors may occur only in the postcompression signal due to changes in the tissue structure with the applied compression. We found that purified Wnt2 induces the phosphorylation of both Lrp5/6 and Dvl-2/3, and activates beta-catenin in SN4741 dopaminergic cells. Pediatric patients usually have a good voice or cry and a poor airway. Histochemically, gamma-GTP activity was detected intensively in epithelial cells of epididymides and seminal vesicles and weakly in those of anterior prostates, but not in testes under the present conditions. Peak systolic velocities (PSV), end-diastolic velocities (EDV) and resistive indices (RI) in the right ophthalmic arteries (OA), central retinal arteries (CRA) and posterior ciliary arteries (PCA) were measured at baseline by using color Doppler imaging on a masked basis.

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Extensive loss of cytoplasmic and cell nuclear ER-IR was seen when an antiserum against the hinge region of the receptor was used. As no fibroblasts were demonstrable within these regions, the smooth muscle cells were the likely source of the extracellular matrix. These results of in vitro tests and GPC measurements indicated that while bulk modification of the scaffold was processed, its handling was stable during in vitro cell culture for up to 4 weeks. Here, we show that FOXO1 and FOXO3a have an essential function in promoting cell detachment-induced anoikis, resistance to which is implicated in cancer development and metastasis.

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Allergic asthma is caused by inhaled allergens and is characterized by airway eosinophilia, as well as mucus hypersecretion, which can lead to airflow obstruction. Adenylate cyclase in a fibroblast mutant defective in glycolipid and glycoprotein synthesis. The pol gene of 349 HIV-1 patients belonging to the Italian Cohort Naive for Antiretrovirals (ICONA) were genotypically analyzed to study the prevalence of antiretroviral-associated resistance mutations. From the outer medullary collecting duct (OMCD) to the initial portion of inner medullary collecting duct (i-IMCD), the labyrinth became less complicated due to the mingling of wide flattened ruffles.

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To negate the excess risk of endometrial hyperstimulation, an adequate progestin dose must be given in a continuous combined regimen or for an appropriate number of days in sequential regimens (10 days or more for some progestogens or 12 days or more for other progestogens). Rosuvastatin in the prevention of stroke among men and women with elevated levels of C-reactive protein: justification for the Use of Statins in Prevention: an Intervention Trial Evaluating Rosuvastatin (JUPITER).

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Growth is one of the fundamental aspects in the development of an organism. Although dsp28 is induced by cold in addition to desiccation stress, it does not contribute to the freezing point depression (thermal hysteresis) observed in Tenebrio hemolymph. Macroscopic and microscopic examinations were performed on 39 and 4 cadavers, respectively.

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Angiogenesis, the sprouting of capillaries from existing blood vessels, is central to tumour growth and progression, however the molecular regulation of this process remains to be fully elucidated. Blood samples were obtained from cattle and buffaloes over extended periods of time by remote controlled methods at 4-hourly intervals.

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Crocin (20 microM) alone did not affect the potentiation induced by weak tetanic stimulation (11 pulses at 100 Hz). Inhaled efficacious dose translation from rodent to human: A retrospective analysis of clinical standards for respiratory diseases.

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Bovine myoblast cell production in a microcarriers-based system. Recombinant retroviral genomes encoding a chromosomal human beta-globin gene have been used to transduce murine haematopoietic stem cells in vitro.

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Significance of gastric antrum contraction in liquid meal emptying. Consecutive events triggering medical emergency team activation in adult patients admitted to the gastroenterology wards of the Asan Medical Center were reviewed. Earlier recognition of this fungal infection improves the prognosis.

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Patterns of failure after stereotactic radiotherapy of intracranial meningioma. The Danish contribution to evaluation and treatment of bleeding oesophageal varices. Parents were informed about the nature of the disease, prognosis, and advised for further medical care in a more advanced kidney transplantation centre.

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Synthesis of benzanilide derivatives which have dual alpha 1-adrenoceptor antagonistic action and steroid 5 alpha-reductase inhibitory activity and their structure-activity relationships is described. Patients with hepatobiliary pathology showed an augmentation of peroxide oxidation of lipids (LP), its degree dependent upon the severity of the clinical course of the medical condition in question, being the highest in those patients with viral hepatitis, carcinoma of the head of pancreas, and portal cirrhosis of the liver.

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Ankrd 13 proteins were anchored, via the central region and UIMs, to the plasma membrane, where they colocalized with EGFR. In this population there is a high incidence of cognitive decline and dementia, which has a negative influence on personal life and family functioning, as well as economic and healthcare repercussions. Similarly, platelets from control rats suspended in plasma from endotoxemic rats showed hyporesponsiveness to ADP and collagen.

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Epidemiology of bronchial asthma in children in Olomouc district. Effect of human growth hormone-releasing hormone on the release of dynorphin-like immunoreactivity, luteinizing hormone, and follicle-stimulating hormone from rat adenohypophysis in vitro. Equine surgical facility for hire: practical answer to a costly problem.

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Pseudomonas aeruginosa has emerged as a potential pathogen in the immunocompromised patients and in those who have nasal tubes or catheters. A basic experiment concerning body temperature regulation in various growth stages

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Null mutant mice were found to be more sensitive to supraspinal (i.c.v.) injection of the micro-opioid receptor-selective agonists, morphine and D-Ala(2)-MePhe(4)-Gly-ol(5) enkephalin. Splenocytes were isolated 1, 5, and 8 days postburn (PBD) and cultured with lipopolysaccharide for 5 days.

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A total of 28,500 cases of head injury were reviewed in Taipei City and Hualien County from 1988 to 1992. Fibronectin and laminin binding of urogenital and oral prevotella species. To compare results of medium to longterm sulfasalazine and auranofin treatment in active rheumatoid arthritis (RA). The change of levels of antisperm antibody before and after treatment, pregnant rate, and the number of implantation were investigated in tested mice.

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Feeding on a marsh-living herbaceous plant by black howler monkeys (Alouatta caraya) in central Brazil. One dust and two air samples (one during the day and one during the night) were collected in each center. Breath sounds in the clinical assessment of airflow obstruction. Down-regulation of the receptor for parathyroid hormone (PTH) and PTH-related peptide by PTH in primary fetal rat osteoblasts.

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Efficacy of triclabendazole against Fasciola hepatica in the donkey (Equus asinus). Furthermore, the consistent size of the intrinsic and associational stripes (approximately 275 by 1,800 microns) suggests that they may represent basic functional units in the primate prefrontal cortex. Avoiding the chopping block in curricular reform: reimagining physiology laboratories in the era of integrated medical curricula. To study the association between osteoporosis and emphysema in a model that includes these potentially confounding factors.

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Consequently, the transport of metabolites, ions and water from mother to fetus could take place primarily via transcellular routes. We studied the effect of forskolin on cochlear potentials and found that its perfusion of the scala vestibuli (SV) to a concentration more than 10(-5) M and the scala tympani (ST) to more than 10(-4) M produced a reversible elevation of the endocochlear potential (EP) in a dose-dependent manner.

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A mechanistic approach potentially useful for conducting dose, scenario, species, and route extrapolations of toxic interactions is physiological modeling. Patients often present with urgent conditions that can be handled quickly and easily in the office setting. Samples for assay were available from 69 normal post-menopausal control women, 12 patients with mucinous tumours of the ovary, 26 with serous tumours, 7 with granulosa cell tumours and 8 with various other ovarian tumours. Plasma endothelin did not differ among mixed venous, pulmonary capillary and systemic arterial blood. A noncontact co-culture system of PDLSCs and preosteoblastic cell line MC3T3-E1 or osteoclast precursor cell line RAW264.7 was established, and osteoblastic differentiation of MC3T3-E1 and osteoclastic differentiation of RAW264.7 were evaluated.

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Concentration-related increase in DNA damage was induced after 2h and 7 days exposure to CuSO4 dissolved in culture water. The changes in the cytokine production with age were analyzed transectionally and longitudinally. The da Vinci surgical system (Intuitive Surgical, Sunnyvale, CA, USA) provides the advantages of simplification and precision of exposure and suturing because of allowing movements of the robotic arm in real time with increased degree of freedom and magnified 3-dimensional view. An approach to scoring cursorial limb proportions in carnivorous dinosaurs and an attempt to account for allometry. Choice of a screening strategy depends on financial resources and desired effectiveness.

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Managing hepatitis B reactivation in renal transplant recipients: a 12-year review with emphasis on early detection and early use of lamivudine. However, evidences are still lacking on the superiority of eptifibatide over tirofiban or vice versa in patients with acute coronary syndrome.