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However, oxytocin immunopositive neurosecretory terminals were distributed more heavily in that part of the lobus nervosus bordering the pars intermedia than in the center of the lobe. Buried, absorbable, subcuticular sutures do not significantly increase the degree of inflammation in noncontaminated wounds. Seven female patients with a median age of 6 years old underwent delayed end-to-end anastomosis. Intravenous tissue plasminogen activator and flow improvement in acute ischemic stroke patients with internal carotid artery occlusion. Other than the oral route, which is the preferred one, alternative modalities to administer opioids may be helpful in different clinical circumstances.

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Within 1 wk after helminth infection of the mice, increased numbers of MC appeared in the crypts at the base of the villi, and by wk 2 the number of MC throughout the villi increased by approximately 25-fold. This work prompted us to study oligodendrocyte influences on neuronal survival and death in vitro. Utility of stress perfusion-cardiac magnetic resonance in follow-up of patients undergoing percutaneous coronary interventions of the left main coronary artery. These results suggest that dinucleotide microsatellites represent an under-appreciated source of genetic variation for regulatory evolution.

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Multidrug-resistant tuberculosis in children: two cases and a review of the literature. Usefulness of M-mode, 2-dimensional, and Doppler echocardiography in the diagnosis, prognosis, and management of valvular aortic stenosis, aortic regurgitation, and mitral annular calcium in older patients. Cloning and characterization of a new soluble murine J-domain protein that stimulates BiP, Hsc70 and DnaK ATPase activity with different efficiencies. Comparison of somatic versus psychological scores between Asian and white mothers showed no significant difference across the range of total SRQ scores. PstI fragment polymorphism in the gene of the human ATP synthase beta subunit.

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At the same time, they question the clinical utility of stress testing as a prognostic device. Targeted radiotherapy with 90Y-DOTATOC is a novel, well-tolerated treatment for neuroendocrine tumours with a remarkable objective response rate, survival time, and symptomatic response. Bovine viral diarrhea virus should be considered as a cause of death in young and old New World camelids. Several variables emerged as predictors of contraceptive method used within casual relationships, including method used at first coital experience, age, and frequency of intercourse.

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To obtain normative data for nasalance scores in Middle Eastern English-speaking adult population. To review the literature on communication technologies in rehabilitation for people with a traumatic brain injury (TBI), and: (a) determine its application to cognitive-communicative rehabilitation, and b) develop a model to guide communication technology use with people after TBI.

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Chimeric Mouse model to track the migration of bone marrow derived cells in glioblastoma following anti-angiogenic treatments. Similar behaviour has also been observed from other diffraction techniques in typical ionic melts such as NaCl. Control of autoreactive T cell activation by immunoregulatory T cells (ART). Purification and partial characterization of alpha-N-acylpeptide hydrolase from bovine liver.

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Development of a community-based diabetes and hypertension preventive program. The bottleneck in the cancer biomarker pipeline and protein quantification through mass spectrometry-based approaches: current strategies for candidate verification. To characterize a biomarker for epileptogenesis based on cardiac interbeat interval characteristics.

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Performance improvement system and postoperative corneal injuries: incidence and risk factors. Present status of hepatitis virus-associated hepatocellular carcinoma in Nagasaki Prefecture, Japan: a cross-sectional study of 1019 patients.

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A role for CART in photoperiodic regulation of growth is suggested, because the changes in CART gene expression preceded significant divergence of growth trajectories in the opposite photoperiods. Mitosis-specific phosphorylation and subcellular redistribution of the RIIalpha regulatory subunit of cAMP-dependent protein kinase.

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Telomerase RNA mutants that cause unusually long telomeres with deregulated structure led to severely defective meiosis. A method for determining human mitochondrial aldehyde dehydrogenase (ALDH2) genotypes was developed.

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Factor analysis when used in studies of organization, is not assumed to produce factors that represent unidimensional scales. The neurological symptoms that characterize this form of malarial disease are accompanied by the adhesion of infected erythrocytes to the vasculature of the brain. As this and other clinically relevant targets are discovered, elaborated and refined via the activity of their cognate agents (as was the case for the phosphatase calcineurin via the activity of cyclosporin), a critical opportunity should ensue for structural biology to exert a profound effect on the future development of these therapies. In vivo performances were compared to those of a nonoptimized SR matrix tablet and a reference instant release (IR) capsule, in terms of the observed plasma pharmacokinetic profiles for the parent drug (ucb 11056) and its primary metabolite (ucb 26201), the bioavailability results, and the drug tolerance data.

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Biliary cystadenocarcinoma is a rare, usually intrahepatic neoplasm. The function of Rap1 appears to be evolutionarily plastic, especially in the budding yeast lineages.

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The doses were escalated to 10 and 15 mg/kg/day, resulting in successful eradication of the mucormycosis. Here we have investigated the role of the checkpoint kinases ATM (ataxia telangiectasia mutated) and ATR (ATM- and Rad3-related) in DNA damage-induced inhibition of Plk1. GABAA receptor-mediated responses in the ventromedial nucleus of the hypothalamus of female and male neonatal rats.

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While few would argue with the treatment of acute complications such as superficial venous thrombosis and variceal haemorrhage, the role of interventional treatment in the management of lifestyle limiting symptoms and the prevention of disease progression may be debatable. Treatment of allergic rhinitis with a new long-acting H1 receptor antagonist: astemizole. Preoperative evaluation revealed a mass in the right lower quadrant of the abdomen, possibly originating from the terminal ileum, 1-2cm from the caecum. This study was designed to evaluate recurrence and functional outcome of three surgical techniques for rectopexy: open (OR), laparoscopic (LR), and robot-assisted (RR). We reviewed 29 patients who were treated for advanced mandibular ORN by radical resection and reconstruction with free flaps at our institution.

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Motor function quickly recovered in 11 and speech function in 3 patients. Results of mechanical ventricular assistance for the treatment of post cardiotomy cardiogenic shock.

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A process control run with the UV lamp off resulted in 95 percent infection at a dose of 10(3) oocysts per inoculum. Clients (age range 5-18) see a CMO at the first visit and thereafter a school nurse. Children with cancer or Langerhans cell histiocytosis who were receiving treatment or had completed therapy were eligible. To describe the results obtained from conducting non-hospital mouth surgery in a buccal-dental health unit, to evaluate the quality of care and to monitor its evolution over two years. In contrast, T helper 2 cells neither induce SPI-6 nor convey protection, despite the fact that they trigger DC maturation with comparable efficiency.

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Serum prolactin levels reflected central dopaminergic activity, since both the endocrinologic regulation of prolactinomas and the pathophysiology of acute psychosis have been linked to alterations in dopaminergic activity. When the specimen is charged with an electric current under fixed temperature, the current attains several microAmp in darkness but is usually less than that under illumination by about one order of magnitude.

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Role of surgery for otitis media in the era of resistant bacteria. She developed thrombosis at the left common femoral artery with serum antiphospholipid antibodies. The diagnosis of RSV infection was facilitated by bronchoalveolar lavage. Dimethyl sulfoxide decreases interleukin-8-mediated neutrophil recruitment in the airways. The enzyme S-adenosylmethionine synthetase is involved in the synthesis of S-adenosylmethionine, a methyl group donor and also, after decarboxylation, a propylamino group donor in the bio-synthesis of polyamines.

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In vivo model of cartilage degradation--effects of a matrix metalloproteinase inhibitor. One hundred nine patients were enrolled, and 103 received at least one dose of alemtuzumab. DNA associated with hyperacetylated histone is preferentially digested by DNase I. Investigational drugs discussed include XL-139 (Bristol-Myers Squibb Co/Exelixis Inc), SPC-3042 (Enzon Pharmaceuticals Inc/ Santaris Pharma A/S), CH-5137291 (Chugai Pharmaceutical Co Ltd), SN-29966/SN-29926/SN-3000 (Proacta Inc), withaferin-A (University of Kansas), Reolysin (Oncolytics Biotech Inc), EZN-3889 and EZN-3892 (Enzon Pharmaceuticals/Santaris Pharma), and CBP-501 (CanBas Co Ltd/Takeda Pharmaceutical Co Ltd). Wild-type Praja1, but not its RING finger mutant, promoted ubiquitination of Dlxin-1 in vivo.

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Glucocorticoid synthesis is regulated by ACTH, which acts by accelerating the transport of the precursor cholesterol to the mitochondria where steroidogenesis begins. Our previous study has shown that angiotensin II (Ang II)-NADPH oxidase-superoxide signaling is associated with the reduced cell excitability in the aortic baroreceptor neurons (a primary afferent limb of the arterial baroreflex) from diabetic rats. All in one with chAMPion: a generic luminescence assay platform for any GPCR signaling type. We prepared S130A thiamin phosphate synthase with the intent of characterizing the enzyme-substrate complex.

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Self-healing polymers can significantly extend the service life of materials and structures by autonomously repairing damage. Two pancreatic cancer cell lines, the highly invasive and metastatic cell line PC-1.0 and the weakly invasive and rarely metastatic cell line PC-1, were established from a pancreatic ductal carcinoma induced by N-nitrosobis (2-oxopropyl) amine in a Syrian golden hamster. An association of cervical inflammation with high-grade cervical neoplasia in women infected with oncogenic human papillomavirus (HPV).

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Determination of the glomerular filtration rate in the rat by an undisturbed technique without the collection of urine. ROFA exposure produced an increase in bronchoalveolar lavage fluid (BALF) neutrophils in both SD and F-344 rats.

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Adherence stimulates the inflammatory response by activation of cytokines such as interleukin-1, -6, and -8. The six-day air pouch model of synovitis in rats was used to study the effects of non-steroidal and anti-rheumatic drugs on cell accumulation and exudate formation. All published placebo-controlled trials of naltrexone or acamprosate for alcohol dependence were examined, and, when suitable, data were extracted for calculation of a mean effect size. Late treatment with imatinib mesylate ameliorates radiation-induced lung fibrosis in a mouse model. Eliminating the density-dependent phase shift represents a promising potential application for multicomponent condensates in atom interferometry and precision measurements.

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Outcome of newly diagnosed glioblastoma patients treated by radiotherapy plus concomitant and adjuvant temozolomide: a long-term analysis. In general, rapid and complete formation of ferrihemochrome occurred with arylhydrazines that induced severe anemia. The approach was tested on case and control groups matched for osteoporosis risk factors. A cDNA and two genomic clones comprising highly similar genes that encode a protein with a Myb-related DNA-binding domain were isolated from the resurrection plant Craterostigma plantagineum. In SE-positive subjects, many single-nucleotide polymorphisms were significant, including some on chromosome 6.

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The key to all aspects of the experiment is the accurate characterization of the test material in terms of fiber length, diameter, particulate content, and chemistry. There was no operative mortality and the patients survived 2 to 14 months (mean 5.7 months). Trans-signaling via the soluble IL6R (sIL6R) was linked to chronic inflammation and cancer. Predicting VO2peak from Submaximal- and Peak Exercise Models: The HUNT 3 Fitness Study, Norway. Immunohistochemical analysis of cryosections of brains/pituitaries from juvenile transgenic frogs revealed the nearly exclusive expression of GFP in the intermediate pituitary.

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Effect of streptomycin following exposure to a thermal burn and irradiation. In a fruit fly odor-electric shock associative memory paradigm, we found that learned avoidance lost its specificity for the trained odor and became general to novel odors within a day of training. One therapeutic approach to improving hemodynamics is to increase oxygen delivery in an attempt to overcome tissue oxygen debt.

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