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Waardenburg syndrome (WS) is a rare disease characterized by a sensorineural hearing loss and pigment anomalies of the iris, skin and hair due to mutations in PAX3. Housing attributes and serious mental illness: implications for research and practice. The authors developed a percutaneous endoprosthesis for treatment of aortic dissections. Chartered air ambulances for the international repatriation of patients.

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Transition to community-based nursing curriculum: processes and outcomes. Developing intrinsic self-healing polymeric materials is of great interest nowadays to extend material lifetime and/or prevent the replacement of damaged pieces. A chromatographic method for determining diphenylolpropane in the air of a work area Tyrosine levels are abnormally elevated in tissues and physiological fluids of patients with inborn errors of tyrosine catabolism, especially in tyrosinemia type II, which is caused by deficiency of tyrosine aminotransferase and provokes eyes, skin, and central nervous system disturbances.

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In the remaining half, the neutrophils passed rapidly and without pause from arteriole to venule. Eosinophilic gastroenteritis and gluten-sensitive enteropathy in the same patient. Understanding the pathophysiology of lung injury in the extremely low birth weight neonate is essential when caring for these infants, especially during the first hours of life. Our work introduces a computational model that underwent progressive molding and fine-tuning as a result of its synergistic collaboration with numerous in vitro PAMPA permeability assays. We then performed oral challenge tests with Bronco-aseptilex, sulfadiazine, and other compounds of the commercial syrup.

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The increased thickness of all recti muscles may be influenced by growth (primarily during puberty), and the variations in thickness of the extraocular muscles may be attributable to near-vision stimulus of the inferior and medial recti muscles. Because the trapping project depends on village participation (making, setting, and maintaining the traps), village volunteers and their neighbors learned more about the causes and prevention of sleeping sickness and became much more willing to participate in serosurveys and to seek treatment. There is much uncertainty surrounding the benefits and harms of colchicine treatment. Islet amyloid polypeptide (IAPP) is a 37-residue polypeptide hormone that is responsible for islet amyloid formation in type II diabetes.

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Two weeks after lesioning the Morris maze performance is severely impaired. Abluminal application of NE produced graded vasoconstriction in a concentration range of 10(-9)-10(-6) M. Improvement in esophageal abnormalities in scleroderma has not been previously reported.

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The effect of 4,6-benzylidene-D-glucose (BG) on chemically induced primary hepatocellular carcinomas in rats was tested after daily single injections of 85 mg per kg body weight into the aorta through a canula implanted through the right carotid artery. Adrenoceptor blocking and cardiovascular effects of the optical isomers of amosulalol (YM-09538), a combined alpha- and beta-adrenoceptor blocking agent, and the corresponding desoxy derivative (YM-11133) in rats. The aim of the study was to improve understanding of the relationships between contextual socioeconomic characteristics and coronary heart disease (CHD) incidence in France. Several studies have shown that treating hypertension in patients with chronic kidney disease and proteinuria may attenuate the decline in glomerular filtration rate.

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We used this model vertebrate genome to analyse the genomic organisation of vasotocin and isotocin genes, the teleost homologues of vasopressin and oxytocin. Moreover, a health problem linked to age can have a feedback effect on the manner in which a job is performed. The report suggested the wife to have developed ATL by horizontal transmission of HTLV-I from her husband 31 years after their marriage. However, the actual mechanism of oral detection and the effect of tannins on mastication and swallowing have been little investigated. Functional outcome was assessed using validated scoring systems.

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Effect of protein malnutrition on sex organs of metanil yellow exposed male rats. The correlation between frequency of the microorganisms isolation and their susceptibility to antimicrobial agents at different periods was analysed. Many studies have described laparoscopic or thoracoscopic-assisted esophagectomy in adults. Pharmacokinetic and pharmacodynamic properties of controlled release (CR/ZOK) metoprolol in healthy Oriental subjects: a comparison with conventional formulations of metoprolol and atenolol. bovis R 81/536 glucan-negative (biotype II) to adhere to buccal epithelial cells (BEC) by lipoteichoic acid (LTA) was examined.

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However, the mechanism underlying Ras-promoted tumor metastasis remains unclear. Ten avian serotype 3 paramyxoviruses were isolated for the first time in Israel from passerine and psittacine imported caged birds.

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Congenital absence and hypoplasia of pedicles in the thoracic spine. Usefulness of midazolam for premedication before local anesthesia We evaluated the durability and effectiveness of non-nucleoside reverse-transcriptase inhibitor (NNRTI)-based antiretroviral therapy (ART) in this population.

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The disc moved slightly posteriorly on the condylar head and remained in the glenoid fossa during mouth opening. Associations between baseline ultrasound findings (grey scale (GS), power Doppler (PD) and erosions) and (1) progression to IA and (2) development of CS within an individual joint were measured. In the PBL condition back muscle activity was increased before lift-off. We develop a Bayesian framework to allow differences in interpretation to be examined systematically and the need for a confirmatory trial to be assessed.

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The question whether there is an association between handedness and dyslexia has been investigated in many studies spanning more than 50 years. The transferred tendon did not contract during active ulnar deviation. The presence of longitudinal sinus thrombosis was suggested by unenhanced CT scan, confirmed by colour doppler flow imaging and magnetic resonance angiography, with absence of blood flow in the longitudinal sinus.

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A better understanding of the central nervous system pharmacokinetics of commonly used anticancer agents has also resulted in improvements in the treatment of meningeal cancer. Prophylactic sclerotherapy of oesophageal varices: is it justified? Conformational dynamics of the transcriptional regulator CooA protein studied by subpicosecond mid-infrared vibrational spectroscopy.

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Opiate-dependent subjects experience severe depression as one of the subjective symptoms during withdrawal. Upper gastrointestinal cancer burden in Hebei Province, China: A population-based study. NMDA receptor-antagonists were tested in dose ranges that have previously been found to produce anticonvulsant and anticataleptic (antiparkinsonian) effects in rats.

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The most commonly observed scenario is paraesthesia and dysesthesia as a result of toxic effects of chemotherapies on the distal peripheral nerves. The interrelation between circulating serotonin (5-hydroxytyptamine, 5-HT), cigarette smoking and COPD is however largely unknown. A variation in the cerebroside sulfotransferase gene is linked to exercise-modified insulin resistance and to type 2 diabetes. Correlations showed a significant positive relationship between those head nurses exhibiting a transformational leadership style and the job satisfaction of their staff nurses.

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Cell proliferation was not involved in upregulation of organ size. Lack of education and proper environmental sanitation are contributing factors in this apparent deficiency. Dermatologists and dermatopathologists should be aware of this rare and unique variant of porokeratosis, which, in addition to the atypical clinical presentation and the occasional misleading histology, may portend a better prognosis in terms of malignant degeneration.

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An analysis of thymic function and the possible role of the thymus in stem cell production. The value of real-time three-dimensional transesophageal echocardiography in the assessment of paravalvular leak origin following prosthetic mitral valve replacement. The contribution of nurse practitioners to service delivery in family planning. No direct genetic evidence has yet been provided for primary active chloride transport despite numerous reports of cellular Cl(-)-stimulated adenosine triphosphate (ATP)ases coexisting in the same tissue with uphill chloride transport that could not be accounted for by the three common chloride transport processes.

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Demographic information for all individuals identified as having sustained gunshot injuries was obtained and like data was captured for the entire military population serving in the same time-period. Aggressive management of complications of cloth wear by reoperation is likely to prevent disabling or lethal consequences. A truncated variant of the hepatitis C virus core induces a slow but potent immune response in mice following DNA immunization. Local recurrences were detected by physical examination alone in 42 patients, mammography alone in 47 patients, and both modalities in 23 patients.

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HIV retinopathy, a noninfectious microangiopathy, is the most common ocular manifestation of HIV infection. Future prospects for space life sciences from a NASA perspective. Residents in the experimental groups perceived improvements in the ancillary staff, placed a higher value on informal discussion of patient management problems, and were more satisfied with the outpatient experience. We evaluated the role of the selective ROCK inhibitor Y-27632 on hESC colonies and disassociated single hESCs from two different hESC lines.

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The nongrowing group also showed a significant increase in overbite during the posttreatment period. After preceding surgery and percutaneous radiotherapy, repeated local recurrences and locoregional lymph node metastases had occurred. The thrombocytopenia is typically moderate, with a median platelet count nadir of approximately 50 to 60 x 10(9) platelets/L. Mass-spectrometric analysis indicates that palmitoyl residues constitute the predominant but not the only type of S-acyl group coupled to a lipopeptide carrying the myristoylGC- motif, with smaller amounts of S-stearoyl and S-oleoyl substituents also detectable. Its pathogenesis is discussed even if much attention in recent years has centered on genetic causes since the identification of the ob-gene and its protein product leptin.

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Intensive modification of established risk factors has a profound impact on the natural history of atheroma progression. The reduction in leaf-elongation rate (LER) was correlated with the increase in sap pH.

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Within the group of endogenous factors, besides the well-known photo type skin, as well as genes mutations, are added and the sex hormones, with their significant prognostic importance. To this end quantitative conjugation assays were performed and transconjugants were scored for plasmid-borne antibiotic selection markers. He was treated by percutaneous transluminal balloon angioplasty (PTA) and stent implantation in the left subclavian artery and by PTA alone in the right subclavian artery. Carefully selected patients at both extremes of BMI have good mid-term survival after LVAD and should be considered for LVAD implantation relative to overall risk profile.

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The particular measuring technique and the model of acupuncture meridian are discussed. Understanding the molecular nature of this complex mechanism will eventually lead to insight into the pathogenesis of differentiation disorders of the epidermis, e.g.

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Environmental factors as well as intense physical exertion may influence eosinophil-related bronchial hyperreactivity. Serotonin (5-HT) agonists, selective for 5-HT1, 5-HT2 or 5-HT3 receptor subtypes, were tested for their ability to mimic 5-HT in narrowing the tetraethylammonium-induced calcium-dependent plateau of action potentials recorded from frog sensory neurons.

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In the present study, we examined the effects of response priming on the event-related potentials (ERPs) evoked by target stimuli in a go/nogo task. In contrast, no displaced ganglion cells were labeled after injections of horseradish peroxidase into the optic tectum, which labeled only cells in the ganglion cell layer proper. Performed with inhalation anesthesia under radiological guidance, tracheobronchial recanalization with a self-expandable metal stent is a safe and effective palliative treatment for malignant stenosis.

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Plaque morphology does not add to the sensitivity of stenosis in predicting the presence of symptoms. Interestingly, a single mutation at the corresponding positions of Arg339 or Arg342 responded as the wild-type human secretin receptor in all functional assays, indicating that the presence of one Arg at either position within the RLAR motif is sufficient for a normal receptor function. To localize the precise site of infection we evaluated In-111 Biotin SPECT/CT versus planar and SPECT imaging. Evidence-based health care involves the more formal integration of the best research evidence with clinical expertise and explicit acknowledgment of patient values in clinical decision making, as compared with conventional practice.

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Pain scores were measured at 4 to 8-hour intervals using 100 mm visual analog scales. Magnetic resonance imaging in the planning of initial lumpectomy for invasive breast carcinoma: its effect on ipsilateral breast tumor recurrence after breast-conservation therapy.

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Genetic effects of space hadrons on bacteriophage under Alpine conditions. We used a clinical confocal microscope to study corneal changes in three patients wearing a high water content soft contact lens for the first time. Embryonic Id1 messages are detected during gastrulation on the proximal side of the embryonic ectoderm, which is the border between the embryo proper and the extraembryonic tissues, and the expression of Id3 is found throughout the entire embryo proper. Significant increases in the ratios of spermatic veins 17OHP to A-dione and 17OHP to T, and a significant decrease in the ratio of T to E2, was found 24 h following hCG treatment. However, our experiments on retinal ganglion cells indicate that several apoptotic mechanisms apply in this particular in vivo situation: these include an involvement of oxygenated free radicals and glutathione, cell cycle-related events, and probably the synthesis of proteins promoting neuroprotection or cell death.

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Reliability of a method for evaluating porosity in denture base resins. In addition, computed tomography provides precise information concerning the actual size and location of large but partially thrombosed or calcified aneurysm to better advantage than angiography. found from ixodid ticks in Japan: rapid species identification by 16S rRNA gene-targeted PCR analysis. Numerous studies have identified members of the multidrug resistance protein (MRP) family of ABC transporters as ATP-dependent GS-X pumps responsible for export of various xenobiotic conjugates, and the few known glutathione conjugates of endogenous metabolites. Hofbauer cells refer to a heterogeneous population of fetal macrophages that reside within the functional unit of the placenta known as the chorionic villus.

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The effect of coccidiostats on the growth capacity and the survival ability of Salmonella live vaccine agents Induction of islet cell neogenesis in the adult pancreas: the partial duct obstruction model. Efficiencies of four versions of the AMPLICOR HIV-1 MONITOR test for quantification of different subtypes of human immunodeficiency virus type 1. The main conclusion from these studies was that ketoconazole inhibited fusion of L6 myoblasts by affecting the synthesis of dolichol-phosphate required for the synthesis of lipid-oligosaccharides needed for the synthesis of fusogenic cell surface N-linked glycoproteins.

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We mainly focused on the hypothalamic-pituitary axis, which can be considered as the master axis of the endocrine system of vertebrates and regulates a great variety of functions, including reproduction, growth, metabolism, energy homeostasis, stress response, and osmoregulation. In an effort to simulate the drop in urine pH seen in some racing horses, we examined the effects of ammonium chloride, ascorbic acid, lactic acid and methionine on urine pH in research horses.

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The Albert scale of motor development: a new instrument for the evaluation of motor development. Fundus examination showed healed choroidal ruptures in all three eyes. Leptotrichiaceae, Mycoplasma and Pasteurellaceae showed higher relative abundances in post-mortem lymph node samples collected from fatal cases of BRD in dairy calves, compared with clinically healthy calves without lung lesions. Results from a series of interactions also revealed that the effects of deviant behaviors on sexual victimization varied by gender and age. Moderately fast speeds require substantial energy expenditure and result in the generation of a massive metabolic heat load.

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The persistence, extinction and reinstatement of morphine-induced CPP were established.In clobenpropit group three different doses of clobenpropit (2, 5 and 10 microg/rat, i.c.v.) were administered 15 min after morphine (1 mg/kg, i.p.) was injected. Direct demonstration that homotetrameric chaperone SecB undergoes a dynamic dimer-tetramer equilibrium. A review of cases in the New York State Pesticide Poisoning Registry. The iliac crest was vascularized secondarily by a long rectus abdominis muscle flap with its inferior epigastric vessels intact to obtain an ideal anatomic location between the maxillary defect and microvascular anastomosis site. They express opposed ideas: for the Hippocratics multiple births are the result of an ideal conception, for Aristotle they are regarded as anomalies associated with notions of monstrosity and excess.

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Over the past 20 years, the recognition of nitric oxide (NO) as an endothelial-derived vasodilator has led to remarkable advances in vascular biology awareness. Intensity-invariance of fine time structure in basilar-membrane click responses: implications for cochlear mechanics.

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Unsaturation induces chain disordering, which may be interpreted as an increase in area per molecule of lipids toward the center of the bilayer. Carotid-subclavian bypass as reoperation in the vertebro-basilar insufficiency syndrome Viral infections of the respiratory system in children and clinical findings The authors report the successful treatment of a patient with advanced basal cell carcinoma using the combination of vismodegib, itraconazole, and imiquimod, each of which inhibits a different part of the hedgehog pathway.

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Antioxidants and coronary heart disease: weighing the totality of the evidence. The fact that a defined alteration of the cell surface induces many properties often encountered in transformed cells, without affecting control of cell division, strongly suggests that these alterations in properties are not sufficient to account for the loss of growth regulation. Ten consecutive families with 2 or more patients with SLE, in total 27 patients among 66 individuals, were studied. No difference in pressure was noted between OC-CM and MID-CM groups.