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The synthesis of cationic glycerolipid acetals containing aliphatic and heterocyclic bases Plasmid constructs carrying up to 3.4 kb of DNA used to transform gln- strains gave transformants which showed a wide range of GS activity, in some cases 100 times the wild-type level.

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Atenolol, a cardioselective beta-blocker that does not cross the blood-brain barrier, was then initiated for the infantile hemangiomas and displayed no adverse effect on the thermoregulation of the infant. Radioactive human serum albumin (RHSA) and urea were injected into the pleural cavity of patients with pleural effusions. Production of transforming growth factor-beta 1 (TGF-beta1) by blood monocytes from patients with different clinical forms of leprosy. Blood samples were collected from 10 farmers within seven days before exposure, one to 12 days after exposure, and again 50 to 70 days after exposure. The authors compare the effects of Tween-20, Brij-35, Triton X-100 and X-305 on the development of stain for two methods: (1) with phosphoric molybdenic acid forming a complex with malachite blue and (2) with photometry of nonreduced phosphoric molybdenic complex.

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N-Acetylglucosaminyltransferase-IV (GnT-IV) has two isoenzymes, GnT-IVa and GnT-IVb, which initiate the GlcNAcbeta1-4 branch synthesis on the Manalpha1-3 arm of the N-glycan core thereby increasing N-glycan branch complexity and conferring endogenous lectin binding epitopes. This is consistent with previous reports that a number of peroxisome proliferator-regulated genes contain PPRE-like elements as part of their regulatory sequences, which may be recognized by several receptor combinations. Presence of a group II intron in a multiresistant Serratia marcescens strain that harbors three integrons and a novel gene fusion. Through induction of juxtaposition and tyrosine kinase activity of Jak1, X-gene product of hepatitis B virus stimulates Ras and the transcriptional activation through AP-1, NF-kappaB, and SRE enhancers.

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Plastic responses of neonatal 5-hydroxytryptamine1B receptors to 5,7-dihydroxytryptamine lesions mapped by quantitative autoradiography. In addition, the use of different negative-strand RNA viruses as vectors to efficiently express foreign polypeptides has also become feasible, and these novel vectors have potential applications in disease prevention as well as in gene therapy. Hypoxic-ischaemic encephalopathy (HIE) remains one of the most important neurological complications in full and near full term newborns. This study describes two mechanisms by which progesterone inhibits metastatic spread of endometrial cancer: by stimulating T-cell infiltration and by inhibiting epithelial-to-mesenchymal cell transition (EMT). Raised creatinine levels and impaired renal function may be found in patients with TTC.

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There has been an increase in cholecystectomy and malabsorptive operations during the last 15 years. 3,4,5,6,16,17-Hexadehydro-16-(methoxycarbonyl)-19 alpha-methyl-20 alpha-oxayohimbanium (Alstonine) is a fluorescent alcaloid which has been known to stain tumour cells more efficiently than normal ones.

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Size of Cryptosporidium oocysts excreted by symptomatic children of Santiago, Chile. Compression spinal cord injury was produced by inflating an extradural 2F-Fogarty balloon catheter (L4-L5) for 60 sec. Clinical specimens are, in particular, cerebrospinal fluid, anti-coagulated blood or serum and, exceptionally, post-mortem specimens. The authors present a case of reno-colonic and renocutaneous fistula in a patient with calculous pyonephrosis.

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The intestinal uptake of particles and the implications for drug and antigen delivery. Changes in TCR and CT number in heated tumors were useful and important indicators of tumor response to hyperthermia. For this purpose a simple model of a spherical cavity in an infinite isotropic medium has been used. Cytoplasmic control over the nuclear events of cell reproduction. SAPHO Syndrome Diagnosis and Treatment: Report of Five Cases and Review of the Literature.

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The Interregional New Technologies Committee (INTC) is one evaluation route for new medical technologies or technologies with expanded indications within Kaiser Permanente (KP). When applied to appropriately selected solutes, the model can account for the difference in clinical targets and can explain the failure of other indices, such as middle molecule clearance, eKt/V, and EKR, to account for the differences.

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Glycine and GABAA receptor-mediated chloride fluxes in synaptoneurosomes from different parts of the rat brain. Pathological lability of venous fasting blood sugar regulation in psychotic disease

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To evaluate the efficacy of a monocular drug trial in eyes with normal-tension glaucoma (NTG). Platelet-associated factor XIII provides a means by which to promote clot stabilization and platelet interaction with proteins of the coagulation and fibrinolytic pathways. Finally, a comparison between the hyu gene clusters in several Agrobacterium strains provides insight into the function of D-: selective hydantoin-hydrolyzing enzyme systems in Agrobacterium species. Corticosteroid pulse therapy is the parenteral administration of suprapharmacologic doses of methylprednisolone sodium succinate for short periods.

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We attempted to investigate early elective versus late elective laparoscopic surgery in acute recurrent diverticulitis in a retrospective study. In other words, REM sleep occurs in response to NREM-sleep expression and compensates for some process that takes place during NREM sleep. Synthesis of rigidified flavin-guanidinium ion conjugates and investigation of their photocatalytic properties. Osteomas are benign lesions that may cause life-threatening complications. Type II collagen-induced inner ear disease: critical evaluation of the guinea pig model.

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There are no trials comparing the relative value of medical versus surgical therapy. There was no detectable transport of HRP to cells in pre- and parasubiculum following similar injections in the LEC.

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It could be a method of choice when fewer variables are involved and/or justification of the results is desired. Age estimation by chest plate radiographs in a Thai male population. Age of onset of depression, chronicity, recurrence, subtype of depression, self-harm history and prior treatment history were assessed with structured clinical interviews. After studying this article, the participant should be able to: 1.

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Decompressive colonoscopy with intracolonic vancomycin administration for the treatment of severe pseudomembranous colitis. We describe a sensitive thyrotropin (TSH) assay in the evaluation of thyroxine replacement therapy. Further studies are needed to establish whether GH-RH antagonists produce telomerase inhibition in other tumors. Hospital social workers were asked to describe their roles and functions, with particular emphasis on the amount of time spent doing traditional advocacy on behalf of patients.

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Ten pieces of colon mucosal biopsy specimens were obtained from 31 cases with UC, 17 of which received sulphasalazine (SASP) or SASP plus glucocorticoid and 14 of which received no medication. The PFI process is reviewed and the advantages and disadvantages of a managed service detailed. We developed a protocol to generate DCs from hESCs in vitro in the absence of serum and feeder cells. Link entropy analysis of dense network activation graphs suggests that the majority of connections between electrodes are reciprocal in nature. In order to enhance the robustness to the number of neighbors, in the paper we presented a novel distance to measure the distance between the samples for the purpose of reducing-the influence of distribution of samples.

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edodes has attracted a lot of attention owing to its antifungal activity, antibacterial activity, antiviral activity, hepatoprotective effect, antitumor activities, and immunomodulatory and cytotoxic effects. Ingestion experiments with these cells showed that eosinophils would phagocytose latex beads coated with a mixture of allergen and corresponding allergic human serum.

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Correlations of each LSAS-SR index with its LSAS-CA counterpart were all highly significant. An important breakthrough for exploiting the potential size and diversity of these libraries has been the development of systems for the surface display of antibodies that are physically linked to their own genes.

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Predictors of mortality and end-stage diabetic complications in patients with Type 1 diabetes mellitus on intensified insulin therapy. Emphysematous gastritis (EG) is a rare and often fatal disorder involving infection of the gastric wall by gas-forming organisms. The Hierarchic Dementia Scale is an instrument for measuring the severity of mental impairment based on Piagetian concepts, neuropsychological findings, and the hierarchic nature of decline in mental function. This treatment resulted in initial improvement of diffusion capacity and exercise tolerance, however, 1 year after diagnosis the patient died of progressive pulmonary hypertension. We investigated AVP synthesis and release by the neurohypophyseal system in 9 patients who died from septic shock and 10 controls, and in 20 rats with fecal peritonitis-induced sepsis and 8 sham-operation controls.

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It seems that every type of unit response to serotonin is associated with a definite type of serotonin receptors. Relative radiation dose exposure to vital organs in the thorax could influence clinical outcomes in esophageal cancer (EC). Cefixime is ineffective in treating shigellosis in adults when used in the standard recommended dosage.

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Stereotactic Radiosurgery for Dural Carotid Cavernous Sinus Fistulas. The development of transplants of human embryonic neocortex in the anterior chamber of the rat eye The purB gene controls rhizosphere colonization by Pantoea agglomerans.

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The optimal pH of the proteinase activity of hemorrhagins, BHRa and BHRb, isolated from the venom of Bitis arietans (puff adder) is pH 9. Both cathelicidins were expressed constitutively in the bone marrow of all pigs at all of the ages tested. However, a minority of laboratories utilize only an immediate spin crossmatch as their routine major crossmatch, possibly because contemporary antibody screening tests occasionally miss detecting some unexpected antibodies, and these missed antibodies are more often detected by the anti-human globulin crossmatch than by the immediate spin crossmatch.

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There is some evidence to support the use of acupuncture as an alternative therapy for asthma. They transferred kanamycin, carbenicillin and cephaloridine resistance determinants to recipient strain E.coli K-12 3110.

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Predictor variables measured at baseline included height, weight, and cardiorespiratory fitness. The analysis was further extended to simulate the blood pressure responses to alternative fixed dosage regimens. We demonstrate that normal livers from humans, rats, and mice express substantial levels of SPARC messenger RNA (mRNA).

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Alcohol administered alone disrupted DSST performance, increased ratings of drunkenness, heart rate and skin temperature, and decreased blood pressure. The cost effectiveness of stratified care in the management of migraine. Development of an enzyme-linked immunosorbent assay (ELISA) for quantification of skeletal muscle calpastatin.

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And the operative findings--pericholecystic adhesion, color of GB, and thickness of the GB wall--were evaluated simultaneously. The overall aim of the present study was to investigate retrospectively the feasibility and utility of model-based clinical trial simulation as applied to the clinical development of naratriptan with effect measured on a categorical scale. Cerebral metabolic changes in neurologically presymptomatic patients undergoing haemodialysis: in vivo proton MR spectroscopic findings.

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The content of adenine nucleotides as an index of the energy support for transport Recent attempts to identify cardiovascular risk factors affecting early-stage carotid atherosclerosis, measured by ultrasonographically assessed intima-media thickness, have been inconclusive. For neuropathic pain, the three medications to use are gabapentinoids, tricyclic antidepressants and serotonin norepinephrine reuptake inhibitors plus topical anesthetics. This was supported by the observation that similar interactions were not observed in the case of hindered alpha-carboxyphosphinate homologous derivatives.

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The effects of somatostatin (SRIF) are mediated through five distinct G-protein-coupled receptors (SSTR1-5). In Exp II, proestrous rats and rats given Pb and killed the next day had a peak in cytoplasmic mRNA levels at 1500 h, which was blocked in rats given Pb and killed the same day. Management of intestinal atresia in patients with gastroschisis. The formation of a polymer cluster through the intermolecular hydrogen bonds was also revealed by X-ray crystal structure analysis for the first time in all known 3-hydroxy-4-pyridinone crystal structures. Dopamine turnover rates in hypox rats were significantly reduced in the hypothalamus and the striatum, whereas they increased in the medial septum and medial preoptic area in comparison with sham rats.

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Although an early and accurate prediction of GDM is needed to allow intervention and improve perinatal outcome, no single protein biomarker has yet proven useful for this purpose. This paper presents an integrated non-model and model-based approach to detecting when process behavior varies from a proposed model.

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History and Current Status of Cardiovascular Surgery at the University of Pennsylvania. This article presents a comprehensive review of the literature on the metabolomic studies on BC, highlighting metabolic pathways perturbed in this disease and the altered metabolites as potential biomarkers for BC detection. Sewage sludge spiked or not with organic pollutants had a generally positive effect on the relative diversity of AM fungal populations in planta, whereas after spreading of the sludge spiked with metallic pollutants, no variation was observed in the abundance of different species. Solubilization and identification of essential functional groups of Candida albicans oxidosqualene cyclase.

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Structure of the MDM2 oncoprotein bound to the p53 tumor suppressor transactivation domain. Regional CMRO2 in the frontal cortex, temporal cortex, parietal cortex, white matter as well as brain stem correlated inversely with plasma phenylalanine levels, and rCMRO2 in the occipital cortex correlated inversely with plasma tyrosine levels. Various Gram positive and Gram negative bacteria were shown to bind to glass-adherent mouse peritoneal exudate cells under these conditions, Str. However, complex formation of N-ethyl-, N-heptyl-, N-diethylaminoethyl- and N-diethylamino-propyl-acridines were different. This case appears to be the first reported case in the literature of adrenal failure due to bilateral adrenal infiltration caused by retroperitoneal malignant mesothelioma.

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A luciferase assay using IL-8 promoter genes showed that nuclear factor (NF)-kappaB is absolutely required and activator protein-1 (AP-1) is partly required for the maximum induction of IL-8 by gastrin. Our results show that p21WAF1, but not 14-3-3sigma, imposes a significant G2 delay after DNA damage. The reaction of 2-nitro-benzaldehyde with ammonia gives different products (1a-c) depending on the reaction conditions. A remarkable feature of this device is that while using the pendant drop method, it employs a centrifugal force to deform the liquid droplet. Since these have been shown to stimulate vascular smooth muscle cell growth (VSMCG), we investigated peroxide levels in patients with PAD during PTA and related these results to late clinical outcome.

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The viral and cellular factors contributing to HHV-6A/B integration remain largely unknown, mostly due to the lack of efficient and reproducible cell culture models to study HHV-6A/B integration. The basement membrane and its involvement in carcinoma cell invasion. The number of post-operative haemorrhages and the time interval from operation to post-operative bleeding were registered, along with the need for re-operation. Water acquisition and partitioning in Drosophila melanogaster: effects of selection for desiccation-resistance.

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The findings of increased muscle coactivation, reduced range of motion, and increased loading rate in the operated compared with the contralateral leg support the hypothesis that meniscectomized patients demonstrate modulations in kinetics, kinematics, and neuromuscular activity, which may represent early changes in neuromuscular function that precede and affect development of knee osteoarthritis. All aneurysmal bone cysts showed involvement of chromosome segments 17p11-13 and/or 16q22. Subsequent lumbar commissurotomy or left thoracic cord hemisection abolished the locomotor recovery. These hormonal changes are associated with changes in body composition, visceral obesity, muscle weakness, osteoporosis, urinary incontinence, loss of cognitive functioning, reduction in well being, depression, as well as sexual dysfunction.

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Transcatheter closure of atrial septal defect guided by on-line transesophageal echocardiography. These results suggest that differences in the care received by privately insured, Medicaid insured, and uninsured low-birthweight babies may stem from differences in the resources available to the hospitals that treat these patients. Influence of the temperature and oxygen exposure in red Port wine: A kinetic approach.

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Trust across borders: responding to 2009 H1N1 influenza in the Middle East. Inhibition of renal sympathetic nervous activity by area postrema stimulation in rabbits.