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The protracted and progressive clinical course, despite high-dose parenteral corticosteroid therapy, was altered by aggressive plasmapheresis. Diagnosis is based on the association of imaging showing characteristic features (hepatic calcifications) and on positive blood culture and serology. In our case-study (a karstic catchment) the mechanisms which explain changes in water quality, as far as turbidity and nitrate are concerned, result from a strong continuity between surface and underground waters. To further understand the mechanism of MBP-1 mediated apoptosis, we examined whether MBP-1 modulates the Bcl-2 gene family.

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To determine the reinfection rate of Helicobacter pylori and duodenal ulcer relapse rate in a group of patients followed up long term. Purification and characterization of the imidazoleglycerol-phosphate dehydratase of Saccharomyces cerevisiae from recombinant Escherichia coli. When tested with repetitive electrical stimulation of the lumbar sympathetic trunk (LST) or i.v. Synthetic polypeptide derivatives with TRF hypophysiotropic activity.

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Increasing evidence supports the role of heme oxygenase-1 (HO-1) in cytoprotective response and iron homeostasis. Apoptosis was the major cellular pathway mediating the cytotoxicity of BN107. A common promoter variant of the leptin gene is associated with changes in the relationship between serum leptin and fat mass in obese girls. Effects of nutrient intake on growth, insulin-like growth factors, and their binding proteins in a Laron-type dwarf. A corneal-reflectance, PC-based system (Eyegaze Development System, LC Technologies) provided eye movement measures.

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The availability of nonthoracotomy systems has reduced perioperative morbidity and mortality as well as hospital costs. The confidence intervals (CI) for these postulated incidences were calculated using the expected number of recent infections for each postulated incidence, the actual number tested for HIV, and the known number of HIV-1 positives. Developing leaders via experience: the role of developmental challenge, learning orientation, and feedback availability. The change of position of a moving object in each control time step is determined by a motion function which is calculated from the firing activity of the chaotic neural network. Thin-section axial CT and helical CT with MPRs were used to examine the central tracheobronchial tree for the presence of stenosis in 27 patients who underwent lung transplantation and 17 nontransplantation patients.

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It is generally associated to overcrowding and low social-economic level. Preparation and characterization of biocompatible microcapsules of sodium cellulose sulfate/chitosan by means of layer-by-layer self-assembly. Pituitary gonadotrophin function is controlled to a great extent by the central nervous system and by the feedback action (positive and negative) of sex steroids. Cervical cancer represents the third most commonly diagnosed cancer and the fourth leading cause of cancer-related deaths in women worldwide.

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Post-treatment with Nec-1 also significantly attenuated the ERG b-wave reduction compared with ischemic vehicle controls. However, the correlation of the physiological functions of TDP-43 with these diseases remains unknown.

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Treatment is essentially local, symptomatic and must be accompanied by general measures. This prediction was examined in two experiments that measured the effect of alcohol on reaction time (RT) for tasks that differed in visual spatial attention requirements. Nine drug-gene networks were discovered, as well as dozens of gene-gene and drug-drug networks. Effect of biological electric stimulation on free muscle transfer Two hormone regimens, ethinyl estradiol (100 microg) with levonorgestrel (0.5 mg) or high-dose levonorgestrel (0.75 mg), given within 72 hours of intercourse and repeated 12 hours later, are available for this purpose.

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There were also marked fluctuations in the activity of S-adenosyl-L-methionine decarboxylase in the tissues examined. Like phenytoin and nifedipine, the drug is associated with gingival overgrowth. Expression of both GS1 and GS2 genes is regulated by light, but perhaps through different mechanisms. A combination of low-dose chlorpromazine and neutralizing antibodies inhibits the spread of JC virus (JCV) in a tissue culture model: implications for prophylactic and therapeutic treatment of progressive multifocal leukencephalopathy. Differential binding of S-adenosylmethionine S-adenosylhomocysteine and Sinefungin to the adenine-specific DNA methyltransferase M.TaqI.

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These results suggest that the inhibitory effect of nicotine on DA uptake, when coupled with an nACh receptor leading to an indirect action on the transporter, may play a role in regulating extracellular concentrations of DA. beta-Carotene production in sugarcane molasses by a Rhodotorula glutinis mutant. However, all insulator proteins, with the exception of CTCF, which has also been identified in vertebrates and worms, have been exclusively described in Drosophila melanogaster. Impact of renal transplantation on hypertension regression in recipients at different ages.

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It was considered that, in the majority of individual patients with head injuries, accurate clinical diagnosis of radiologically apparent fractures was not possible. The Hutchinson Smoking Prevention Project: a lesson on inaccurate media coverage and the importance of prevention advocacy.

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Double-label immunofluorescence was used to simultaneously localize the products of genes representative of the pair-rule segmentation class (fushi tarazu), the segment polarity class (engrailed), and the homeotic class (Sex combs reduced, Antennapedia, and Ultrabithorax) of pattern-regulating genes. There was no significant difference in rCBF, CVR, or COGNISTAT score when comparing the left and right sided diseases. Relatively little is known about the cellular and molecular responses of the knee joint meniscus to joint injury, despite the functional importance of the tissue. This limit applies to general population as well as occupational exposure and is well below that which has been shown to be hazardous to health.

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Effect of 2,3,7,8-tetrachlorodibenzo-P-dioxin (TCDD) on the hepatic stellate cell population in the rat. The aim of this study was to compare the value of contrast-enhanced ultrasonography (CEUS) with standard B-mode ultrasound (US) for diagnosis of splenic lymphoma involvement. In patients with pancreas divisum, dorsal duct stenting decreases the rate of recurrent acute pancreatitis but the improvement of chronic pain appears less obvious.

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A significant risk of ANLL was also observed with the use of syntomycin, a drug pharmacologically related to chloramphenicol. Mononuclear cells were collected by leukapheresis and enriched for monocytes by either counterflow centrifugal elutriation, or immunomagnetic selection using Isolex, an automated closed-system device. Relationships among stress, pet attitude, social support, and health status were also examined. Thus, mutations that altered the sequence of the inverted repeat resulted in derepression.

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African-American children may be more likely to develop type 2 diabetes due to obesity-independent hyperinsulinemia and insulin resistance, but appear less predisposed to the obesity-related clustering of risk factors associated with syndrome X. Chemotaxins C5a and fMLP induce release of calprotectin (leucocyte L1 protein) from polymorphonuclear cells in vitro. This finding further delineates the distal boundary of the critical region of CES, with ATP6E being the most distal duplicated locus identified.

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The allelic and the genotypic frequencies of 6 single nucleotide polymorphisms were the same in diabetic patients and in control subjects. Interestingly, we identified two female-specific scaffolds that likely represent W-chromosome-specific sequence. It can be used to facilitate minimally-invasive treatment of early endobronchial tumours and also to palliate obstructive and bleeding effects of advanced endobronchial tumours.

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In this report, we present 2 patients who exhibited a similar multisystem disorder associated with gangrenous changes in the lower extremities. Coordination of protein and mRNA abundances of stromal enzymes and mRNA abundances of the Clp protease subunits during senescence of Phaseolus vulgaris (L.) leaves. Sphingosine kinase from Swiss 3T3 fibroblasts: a convenient assay for the measurement of intracellular levels of free sphingoid bases. We also found that serum specimens from healthy individuals contained antibodies cross-reactive with HHV-8 glycoprotein B that can potentially cause false-positive reactions in lytic PEL-based IFAs. We also show that dATP and dGTP insert differently opposite template T/U, and that the basis of selection of dGTP over dATP is a hydrogen bond between the N2 amino group of dGTP and Gln59 of Poliota.

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In Study 1, PNT30-A and PNT30-B were found to be internally consistent, and accuracy scores on these subsets of items were highly correlated with the full PNT. Specificity can be achieved via JA-independent processes and spatio-temporal changes of JA-modulating hormones, including ethylene (ET), salicylic acid (SA), abscisic acid (ABA), auxin, cytokinins (CK), brassinosteroids (BR) and gibberellins (GB).

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Yushan Black pigs were uniformly resistant to F4ab, and Jinhua pigs were predominantly resistant to F4ac. cGMP-dependent protein kinase inhibitors block light-induced phase advances of circadian rhythms in vivo. One patient had progressive renal scarring on scintigraphy after cystoplasty. The data stem mainly from two databases containing about 11 500 cases brought before the Norwegian Board of Health Supervision. In contrast to VPD which is biotransformed to VPA, the aforementioned cyclopropane derivatives were found to be stable to amide-acid biotransformation.

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Brain cancer risk and electromagnetic fields (EMFs): assessing the geomagnetic component. Drug resistance is a major obstacle to successful cancer chemotherapy. In contrast, RNAi of NOXO1 resulted in no significant changes in NO and superoxide levels in response to LSS but significantly reduced superoxide while increasing NO in response to OSS. Drug stimulation of topoisomerase II-mediated DNA cleavage is remarkably attenuated in the aza-bioisosteric derivatives, suggesting that other non-enzyme-mediated cytotoxic mechanism(s), possibly connected with free radical production, are responsible for efficient cell killing. A new approach to investigate the effect of pericapillary gradients, caused by the particulate nature of blood, on oxygen partial pressure (pO2) in tissue is presented.

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Non-invasive ventilation (NIV) reduces the need for intubation and the mortality associated with an exacerbation of chronic obstructive pulmonary disease (COPD). This study assessed prevalence of EMF-related and EMF-nonrelated symptoms, anxiety, depression, somatization, exhaustion, and stress in people with MP-related symptoms or EHS versus a population-based sample and a control sample without EMF-related symptoms. Our results indicate that this model provides constant functional and histopathological lesions according to impact energy. However, pili and fibronectin-binding proteins could be associated with recurrence because FCT-4 isolates which harbour two fibronectin-binding proteins are more frequent among recurrent isolates.

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FTY720 (fingolimod) is an immunomodulatory drug capable of preventing T-cell migration to inflammatory sites by binding to and subsequently downregulating the expression of sphingosine-1 phosphate receptor 1 (S1P(1)) leading in turn to T-cell retention in lymphoid organs. Despite early subsidence, interbody fusion cages successfully distracted and preserved interbody spaces. These findings indicate that alternative isoforms of SNAP-25 may play distinct roles in vesicular fusion events required for membrane addition during axonal outgrowth and for release of neuromodulatory peptides and neurotransmitters. The N terminus of hamster polyomavirus middle T antigen carries a determinant for specific activation of p59c-Fyn. An apparent de novo terminal deletion of chromosome 2 (pter----p24:).

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This is the first report of milk-alkali syndrome not caused iatrogenically, but by recreational usage of oyster shell preparations of betelnuts. We investigated how microglia, the resident macrophages of the brain, stimulate glioblastoma cell invasion. Integrated, automated revenue management for managed care contracts. Root canal filling after apicoectomy, as seen on the scanning electron microscope Use of enzyme activities as indices of maximum rates of fuel utilization.

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The preoperative tumor histology was compared with the final pathological findings. Data from approximately three hundred cases are summarized in this review.

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Experimental creation of fusiform carotid artery aneurysms using vein grafts in rats. The present study showed subclinical restrictive type of pulmonary dysfunction in SCA, and possible presence of upper airway obstruction. Because the release of eIF4E from its binding protein as a result of phosphorylation is followed by formation of a messenger RNA cap-binding complex that includes the initiation factor eIF4G, we evaluated the association of eIF4G with released eIF4E and showed that it was increased by CCK. The biological role of these cells and the antigens that they recognize are not clearly understood, although recent findings indicate that gamma delta T cells in general influence both innate and antigen-specific adaptive host responses. Alkaline hydrolysis of the esters released two water-soluble phenolics separable by C(18) HPLC.

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No antigenic similarities in the LPS of strains 1536 and 7317 were revealed. A total of 41 PR patients (11 males, 30 females) were enrolled in this study from April 1999 to March 2000. Marker molecules were used to estimate absorption from each colostrum feeding. The combination of PE and corticoid therapy in severe forms of HSP was associated with fast improvement and good long-term outcome. Oxidative stress contributes substantially to the pathophysiology of diabetic nephropathy (DN).

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Treponema denticola is an oral spirochete associated with periodontal diseases. Demographic and serological data were used to address risk factors for HIV infection.

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These displays were compared with a traditional display that showed pressure and flow values in five separate graphs. Low infectious complications in segmental living related small bowel transplantation in adults.

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KEYnet is a database where gene and protein names are hierarchically structured. At an average followup of 37 months, there were 15 good, 4 fair, and 2 poor results. The number of genetic disorders detectable antenatally by the use of DNA probes has risen rapidly. First, we looked at the effects of a secondary cleft lip repair in three individuals.

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Interventions included oral nutrition supplementation, food modification, dysphagia management, eating assistance and supporting the social element of eating and drinking. Identification of the heat-shock sigma factor RpoH and a second RpoH-like protein in Sinorhizobium meliloti.

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According to social learning theory, stronger relationships between parenting style and self-regulatory processes would be expected from the parent who is the same sex as the respondent. The effect of sodium deoxycholate given by gavage with heparin on the histology of the intestinal mucosa of the rat.

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Testicular function in boys affected by cryptorchidism was similar to the testicular function in normal controls. Use of Prescription Drug Samples in the USA: A Descriptive Study with Considerations for Pharmacoepidemiology.

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Several factors involved in regulation of bone mineral metabolism were compared in male and female Fischer 344 rats of different ages (1, 2.5, 6, and 18 months). In other neural cell types of the CNS, GLAST expression was not detectable. High-resolution transmission electron microscopy is used to observe the intermediate state of pearl-necklace-like aggregates that form a chain-like configuration of Cu(2)O nanoparticles intertwined into nanowires. Chromoblastomycosis caused by Rhinocladiella similis: Case report.

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The present study examines the effect of the EBV replicon vector system and its application to a suicide gene therapy for melanoma in mice. Growth and development: congenital adrenal hyperplasia-glucocorticoids and height. It also describes the recent consolidation of providers in the Twin Cities, as well as the activities of large purchasing coalitions.

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The primary outcome measure, defining cardiac injury, will be high-sensitivity troponin-T over 6 cycles of chemotherapy and 12 months follow-up. In combination with other strategies, hyperosmolarity and desiccation are frequently used by the food processing industry as a means to prevent bacterial proliferation, and particularly that of foodborne pathogens, in food products. High-performance liquid chromatography of porphyrin methyl esters.

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This brief review considers recent information on the role of focal adhesion-associated protein tyrosine kinases in integrin-regulated cell signalling. Concomitant combination therapy for HIV infection preferable over sequential therapy with 3TC and non-nucleoside reverse transcriptase inhibitors.

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The changes were specific for these four enzymes and occurred to the same degree in tumor mucosa and the polyp mucosa. Differences in environmental temperature, ethanol and sucrose associated with enzyme activity and weight changes in Drosophila melanogaster. Epistemologic constraints to the development of a theory of nursing.

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This knowledge is the background for the development of combined strategies with biomaterials. Myth, misunderstanding and misbelief can perpetuate the notion that it is inappropriate for a female nurse to catheterize a male patient. Participants were recruited through a newspaper advertisement and flyers posted in public places in Minneapolis and St.

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Normal values for 2,3-diphosphoglycerate (2,3-DPG) did not change after ascent at 16 and 42 hours. An auxin-binding protein is localized to the plasma membrane of maize coleoptile cells: identification by photoaffinity labeling and purification of a 23-kda polypeptide. Programmed cell death 1 gene polymorphisms is associated with ankylosing spondylitis in Chinese Han population. A complex of methodical devices, which observance will ensure reliable CSD of the genus mentioned, is proposed. Despite its inadequate sensitivity and specificity for myocardial injury, creatine kinase-MB remains an essential component in assessing re-infarction or infarct extension, as well as in monitoring reperfusion after thrombolytic therapy when combined with myoglobin.

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There is also a comparison of the results obtained from similar studies over a period of four decades to those in our study, which reveals that the post-rhinoplasty deformities noted in these studies occur with a similar frequency to those in our paper. Neuropsychological performance was assessed by using a standard battery of eight tests (NPZ-8 test battery).