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Endothelial cells produce a factor that directly stimulates the enzymatic activity of soluble guanylate cyclase. To examine the association of unresolved and unclassifiable attachment with dissociative symptomatology in a sample of 133 adolescents in psychiatric treatment. The relation between duration of breastfeeding and lead levels was assessed with Pearson product-moment or partial correlation coefficients. The 11 profiles predicted differentials in nursing home length of stay, and service use by various classes of caregivers. It seems likely therefore that conclusions derived from British studies can be applied to helminth communities of eels on the continent.

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The effects of a benzodiazepine receptor antagonist beta-carboline ZK-93426 on scopolamine-induced impairment on attention, memory and psychomotor skills. Consnesus for diagnostic pathology in biopsies of chronic gastritis and epithelial neoplasms We consider an active cell motility process in which internal polarity is governed by a positive feedback from cell displacements, a mechanism that can result in highly persistent motion when constrained by an oriented ECM structure. Good efficacy of the drug was observed in the treatment of acute dysentery evident from the disease rapid favourable time course: by the 2nd day the body temperature lowered and the abdominal pains alleviated and by the 4th to the 6th days the stool came to the normal. Maximal expiratory flow-volume curves and diffusing capacity were measured in each subject.

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The consideration of sample size and power during the planning stages of clinical research is crucial to the subsequent interpretation of study results, especially if the study is negative, and yet this point is often neglected in the medical literature. Both endoscopic measurements of bile acids and BIDA scintigraphy appear to be useful methods for determining duodenogastric reflux, but neither may be accurate enough to quantify minor degrees of reflux. Mitogen stimulation and addition of IL-4, IL-6, IL-10, IL-13 and TGF-beta significantly increased both autologous anti-RBC binding and antibody secretion in AIHA patients compared with controls.

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Late identification of disease, lack of prior treatment such as laser or cryo, and higher incidence of narrow-narrow funnel configuration were responsible for the poor surgical results noted in this series. Group A (the treatment group) included nine patients who were to have a transtibial amputation, one patient who was to have a disarticulation at the knee, and one patient who was to have a transfemoral amputation.

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Re-insertion of SEMS for a second obstruction due to colorectal cancer after SEMS treatment is useful for terminal treatment for maintaining QOL. Apart from previously reported Trf4p and Trf5p target RNAs, this analysis along with in vivo cross-linking and RNA immunopurification-chip experiments revealed that both the TRAMP4 and the TRAMP5 complexes stimulate the degradation of spliced-out introns via a mechanism that is independent of the polyadenylation activity of Trf4p. There was no evidence for a short-term beneficial effect of (poly)phenol intervention on microcutaneous vascular response or pulse wave velocity, and no evidence for a benefit on established or novel risk factors in overweight or obese subjects. Yet, when a narrow stripe of fluorescence is bleached across a beta3 integrin-labeled focal contact, recovery is complete within 16 min.

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The high incidence of hypertension after renal transplantation contributes to the risk of cardiovascular morbidity and mortality in renal transplant recipients. No difference between types of feedback was found in either patient group.

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mRNA was extracted from small (0.09 g) samples of growth cartilage from the proximal tibiotarsus of three-week-old broiler chicks. The isolation and analysis of human ocular RNA is problematic due to variables such as rapid degradation, tissue composition, and melanin contamination. Hepatic bipolar radio-frequency ablation between separated multiprong electrodes. The presence of spectroscopic abnormalities in a stable metabolic condition, in particular the rise in glutamine/ glutamate, indicates that the metabolic balance on cerebral parenchymal level is less optimal than estimated from biochemical analysis of urine, plasma, or cerebrospinal fluid. Renal dysfunction was not found to increase exposure of liraglutide, and patients with Type 2 diabetes and renal impairment should use standard treatment regimens of liraglutide.

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Survival rate was modeled as function of AgNOR expression by Cox regression models controlled for staging, histologic grade, age, and sex. The hypothesis of the present study was that titanium renders the stent surface biologically inert, with reduced platelet and fibrinogen binding.

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In most patients, HTL frequencies dropped immediately after transplantation, but returned to pre-HTX values later after transplantation. New data demonstrating the involvement of pertussis toxin-sensitive inhibitory G-proteins in induction of oocyte maturation by the maturation-inducing steroid (MIS) in teleosts is also presented.

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Blood-flow of liver tissue and systemic arterial blood pressure did not show any severe decrease under the continuous endotoxemia. Pharmacological modulations of adrenergic phenotype in medullary C2 and C3 cell groups of adult rat.

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Studies of tissue bioenergetics are very important to gain insight into the effects of weightlessness on the animal and human body. The current investigators suggest further investigations, to include Tanner staging in order to understand the extent to which increases in maturity influence alterations in laxity.

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Toward an artificial Golgi: redesigning the biological activities of heparan sulfate on a digital microfluidic chip. On the contrary, this stream was accompanied by less side effects than the ECT only stream in this study. CYP3A4 expression variability is not influenced much by genetic polymorphism. The prodrug behaviour of 3-MNM and nicomorphine for morphine and 6-MNM, respectively, is discussed. The objective of this article is to emphasize that there are definite principles by which the muscles respond to occlusal contacts.

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The yeast-based two hybrid has been used to identify a novel protein that binds to the intracellular domain of the type 1 receptor for tumor necrosis factor (TNFR-1IC). With a modern therapeutic strategy limb salvage with an adequate function after reconstruction of lower extremity fractures with soft tissue defects can be achieved in the majority of patients. Serum osteocalcin (BGP) levels in normal men: a longitudinal evaluation reveals an age-associated increase. The effect of hydrostatic pressure treatment on the induction of mitogynogenesis in the eggs of Japanese flounder Paralichthys olivaceus (Temminck et Schlegel) by using heterospecific sperm were studied.

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To avoid methodological constraints of clearance measurement with precise urine recollection, the index proposed by Cockcroft and Gault is highly reliable and widely used. A simple surgical procedure to improve drainage and ventilation in the treatment of chronic otitis externa in dogs.

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To investigate potential mechanisms responsible for growth enhancement by calcium, the rat BMSC cell cycle progression was analyzed by fluorescence-activated cell sorting (FACS), and induction of apoptosis confirmed by cytofluorimetric analysis using propidium iodide and Annexin V-FITC double staining. Glycerophospholipid synthesis: improved general method and new analogs containing photoactivable groups. Sequence heterogeneity of PsaA, a 37-kilodalton putative adhesin essential for virulence of Streptococcus pneumoniae. Internal amino acid sequences were used to construct degenerate primers for polymerase chain reaction-mediated cloning of cDNA for the enzyme.

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Postal survey to doctors and nurses at all sexual health, family planning, student and youth health centres, and randomly selected general practitioners. Immunomodulatory effects of stem cells: Therapeutic option for neurodegenerative disorders. Efficacy of an analysis of lymphocyte subsets in predicting the clinical response to alpha-interferon therapy in thalassaemia patients with chronic infection by hepatitis C virus: a pilot study.

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G972R polymorphism of IRS-1 in women with polycystic ovary syndrome. Adrenal-posterior pituitary imbalance in digestive cancer patients

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Concordantly, hypoxic tumor cells show an impaired p53 Ser46 phosphorylation in response to treatment with the chemotherapeutic Adriamycin. The incidence and aetiology of failure, and its clinical presentation, are reviewed. A series of experiments were designed to examine the potential induction of apoptosis by nitric oxide (NO) donors on cortical neuronal cell culture. Chondrogenesis in a hyaluronic acid scaffold: comparison between chondrocytes and MSC from bone marrow and adipose tissue. However, Sal A decreased climbing and swimming time and increased time spent immobile in the forced swim test.

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Cost analysis of fentanyl and remifentanil in coronary artery bypass graft surgery without cardiopulmonary bypass. Eleven patients with pancreatic metastases, 4 women and 7 men with a mean age of 62.45 years, were examined in a period of 5 years.

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An increasing number of surgeons perform sentinel node biopsy to identify melanoma patients with early lymphatic dissemination who may benefit from regional node dissection or adjuvant therapy. A young man with diabetic ketoacidosis developed the clinical features of cerebral oedema. Disruption of KV2.1 somato-dendritic clusters prevents the apoptogenic increase of potassium currents. Mutation of A677 in histone methyltransferase EZH2 in human B-cell lymphoma promotes hypertrimethylation of histone H3 on lysine 27 (H3K27). The microorganisms passed through the dentinoenamel junction and invaded dentin, which was characterized by calcospherites and large amounts of interglobular dentin.

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Involvement of prolactin-releasing peptide in the preovulatory luteinizing hormone and prolactin surges in the rat. The bioassay-guided fractionation of the MeOH extract of the plant led to the isolation of an alkaloid, lycaconitine, as an active principle.

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Detailed are methods whereby the activity of fluorine-18 can be measured. This paper is a case report on the results of an ovarian stimulation performed in the days following an induced abortion.

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Incubation with AluI was performed beforehand to increase DNA breaks near telomere sequence areas. This review of the literature on the epidemiology of achalasia lends support to the idea that pooling of resources and collaboration at an international level is required, if any significant progress in the cause, treatment, and prevention of the disease is to be made. Chronic myelogenous leukemia (CML) is characterized by the presence of a specific chromosomal translocation between the long arms of chromosomes 9 and 22 that results in the fusion of BCR encoded sequences upstream of exon 2 of c-ABL. Gatekeepers with limited time and resources can benefit from the accessibility, simplicity, and flexibility of Web-based training. Specific recommendations can be made for remediation of language and perception after left and right hemisphere stroke, respectively, and for the remediation of attention, memory, functional communication, and executive functioning after TBI.

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Although the individual transcription factors that comprise this AP-1 DNA binding complex had not been identified, we discovered that these proteins were immunoreactive to the cAMP responsive element binding protein (CREB) and also recognized the CRE element. The sentinel lymph node (SLN) mapping technique has been used in breast cancer and melanoma, and was recently described for colon cancer.

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The present study aimed at accessing the natural history of untreated asymptomatic bacteriuria in diabetic patients observed for 14 years. The purpose of this study is to analyze the seasonality of the psychiatric emergencies visited in a casualty department, prospectively, during twelve consecutive months.

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Re: Postoperative ventilatory dependency following thymectomy for myasthenia gravis. Graphene possesses great potential for cholesterol extraction from cell membranes due to its distinct porous structure and outstanding surface adhesion. Gliomas have been classified according to their histological properties. The implications of these findings for assessing depression in the medically ill are discussed. Pulsing direct current-induced repair of articular cartilage in rabbit osteochondral defects.

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European neurology from its beginnings until the 15th century: an overview. Indications and complications of therapeutic disposable Acuvue contact lenses. The dose required is usually lower than in the non neurological patients. We studied which, age of the patient or density of the breast accounts for the sensitivity of mammography and ultrasonography (US).

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To investigate the impact of in utero exposure to di-n-butyl phthalate (DBP) on the apoptosis of testicular cells in the pubertal male rat offspring. Both control and myopathic muscles exhibited potentiation of peak isometric force during the postextrasystolic contraction which was associated with an increase in the peak intracellular calcium transient. Evaluation of Subclinical Left Ventricular Systolic Dysfunction in Chronic Asymptomatic Alcoholics by Speckle Tracking Echocardiography. Effective pharmacological treatment exists to reduce nystagmus, particularly in acquired nystagmus and, more recently, infantile nystagmus. Alteration of product specificity of Rhodobacter sphaeroides phytoene desaturase by directed evolution.

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Bernard Fox, phd: The Promise of Immunotherapy in Curing Cancer. Given the paucity of epidemiological data on the natural history of suicidal behaviors among youths, more epidemiological studies of the antecedents and consequences of the range of suicidal behaviors among children and adolescents are needed. Plasma prostaglandin E(2) metabolite levels during labor induction with a sustained-release prostaglandin E(2) vaginal insert. Peculiarities in wall structure of the arteries in the trabecula septomarginalis are interpreted as adaptive processes of the vascular wall to the extraordinary stress on those vessels. A sample of 129 consecutive clients out of those 256 who self-referred to the DCF during the 13-month observation period (i.e., from November 2002 to December 2003) was interviewed both at baseline and at 1-, 2-, 3-, and 6-month follow-ups.

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Like in BaF3 cells, a TPO-induced signaling complex containing p85PI3K is detectable in MKs expressing T61Mpl and is probably responsible for PI3K activation. Recent work has shown that CD22 specifically recognizes sialic acid linked alpha2,6 to terminal N-linked oligosaccharides on selected cell surface glycoproteins. Use of the patch was associated with plasma nicotine concentrations that were comparable to smoking or to the use of other smoking-cessation devices. Intracellular levels of cysteine (CSH) and reduced glutathione (GSH) in the kidney and liver of rats from the newborn to the adult period have been determined using a sensitive high performance liquid chromatography method. These results are consistent with an autoregulatory response of the retinal circulation to increased inner retinal oxygen tension after PRP.

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Differential display comparing nontransfected human NB NBL-S cells to three AS MYCN-expressing cell lines (NBAS-4, -5, and -6) yielded nine differentially expressed cDNAs designated NDDE:1-9, for MYCN-dependent differential expression genes. Glucosamine-6P-deaminase (EC 3.5.99.6, formerly glucosamine-6-phosphate isomerase, EC 5.3.1.10) from Escherichia coli is an attractive experimental model for the study of allosteric transitions because it is both kinetically and structurally well-known, and follows rapid equilibrium random kinetics, so that the kinetic K(m) values are true thermodynamic equilibrium constants.

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Our findings show a change in clinical presentation of shigellosis in this setting, as the disease may be now more pronounced, this is concurrent with a change in antimicrobial resistance profile. Cdc6 and Cdc28 can be coimmunoprecipitated from extracts, Cdc6 is retained on the Cdc28-binding matrix p13-agarose, and Cdc28 is retained on an affinity column charged with bacterially produced Cdc6. Electron microscopy of neuronal cells showed immunoreactivity localized in the cytoplasm and nucleus. The frequency and amplitude of GnRH pulses determine gonadotropin subunit gene expression and secretion of pituitary LH and FSH. The diagnostic significance of the 3D-reconstructed MRI in vestibular schwannoma surgery: prediction of tumor origin.

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Effects of the teratogenic folic acid antagonist, 9-methyl pteroylglutamic acid on uronic acid levels in fetal rat limbs. In the interface region a direct bone formation between the hydroxyapatite graft and the adjected cancellous bone was visible in all cases during follow-up. Although, the presence of LVI in node-negative patients is an adverse prognostic factor on univariate analysis of disease-specific survival, it is not an independent prognostic factor on multivariate analysis. VEGFA, VEGFB and PlGF bind to VEGFR1, which is a negative regulator of endothelial cell function at least during embryogenesis. Tuning the electronic structure of heterogeneous metal catalysts has emerged as an effective strategy to optimize their catalytic activities.

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Renal replacement therapies in the elderly: renal transplantation and continuous ambulatory peritoneal dialysis. The characterization results indicated the Pt-Fe alloy was formed in the Pt(3)Fe/C catalyst prepared using a citric-acid-assisted NaBH(4) reduction method (CA-NaBH(4)). A threshold plasma level for patients who will respond to this medication is suggested.

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Laparoscopic surgery usually requires a pneumoperitoneum by insufflating the abdominal cavity with carbon dioxide (CO2). The vital statistics collected by the national and international registries and organizations include information on oral cancer.

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Susceptibility of nude mice carrying the Fv-4 gene to Friend murine leukemia virus infection. Kinetic study on the photostability of solid vesnarinone and the equivalent relationship between daylight and lamplight. The purpose of this study was to determine the significance of mechanical energy generation and transfer in the upper limb in generating the racket speed during table tennis topspin forehands. TGF-beta stimulation does, however, lead to the striking down-regulation of p27Kip1 expression during G1 in a manner consistent with the timing of cyclin E-cdk2 activation. Irreversible EGFR-TKIs are expected to overcome the reversible EGFR-TKI resistance of lung cancer harboring T790M mutation in EGFR.

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According the European Working Group on Legionella Infections the disease continues to occur sporadically or in small outbreaks, usually in connections with the survival of legionellae in hot water supply systems. The model was utilized to explore the potential mechanisms of NOB suppression associated with intermittent aeration, considering DO limitation, direct pH effects on enzymatic activities, and indirect pH effects on activity via substrate speciation. Dried Plum Ingestion Increases the Osteoblastogenic Capacity of Human Serum. Rapamycin significantly potentiates agonist-induced platelet aggregation in a time- and dose-dependent manner. Vascular access procedures for haemodialysis--potential hazard of regional anaesthesia.

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Several pregnancies resulted from in vitro- and in vivo-derived blastocysts, and two pregnancies were carried to term resulting in one live birth. By contrast, (co)products are not involved in the behaviours exhibited by younger children on these tasks, or simplified versions that are within their ability. The effect of MCP-1 on proliferation of HRPE cells was examined by MTT assay.

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The intraperitoneal doses of cisplatin tested were 5.0, 7.5 and 10.0 mg/kg. The ability of iron utilizing by means of siderophores produced by donor strains--the members of the genus Acinetobacter (8 strains) by 24 staphylococcal strains was investigated. Reclassification of Desulfotomaculum auripigmentum as Desulfosporosinus auripigmenti corrig., comb. It contains a putative signal sequence as well as a transmembrane domain that divides the molecule into an extracellular domain at the N-terminal side and a cytoplasmic domain at the C-terminal side. Mini-implants were used to establish a setup for computerized tomographic imaging and a surgical template.