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To compare neoadjuvant chemoradiotherapy and surgery with surgery alone for resectable esophageal carcinoma. When patients had more than one complication, only the seminal one was counted, or the most serious one if complications occurred contemporaneously. Sibling involvement in childhood chronic heart disease through a bead program.

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The binding affinities to tartaric acid and binding thermodynamics in different media were investigated by variable temperature (1)H NMR and ITC experiments, the two methods giving consistent results. Data were collected with a demographic data form, that is, the Nausea and Vomiting in Pregnancy Instrument and Pregnancy Unique Quantification of Emesis and Nausea. With a water fluoride content of 2.75 mg F/l a very mild fluorosis is difficult to avoid also with normal water consumption during the 1st year of life. Repeated lower mesentericography in the evaluation of the effectiveness of radiotherapy of rectal cancer Finally, our results do not support a role of M(1)/M(4) receptors in mediating antipsychotic-like effects of clozapine.

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Biochemical correlates were pH, bicarbonate, base excess (BE), chloride, potassium, and sodium. The function of the rod photoreceptors, as well as the inner retina, is altered in infant rats with a history of oxygen exposure. Double survival despite cord intertwining in monoamniotic twins. Efficacy and safety of pazopanib in patients with metastatic renal cell carcinoma. Cancer of pleura in pulmonary asbestosis determined morphologically in vivo

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Approximately one third of humans, depending on colonization of the gut by methanogenic archaea, are considered methane producers based on the classification terminology of high and low emitters. The human saphenous vein in pharmacology: effect of a new micronized flavonoidic fraction (Daflon 500 mg) on norepinephrine induced contraction. A spinal ventral root response was measured following the activation of peripheral fibres by noxious (heat at 48 degrees C, capsaicin, bradykinin) and innocuous (brush) stimuli in a preparation of the neonatal rat spinal cord-tail maintained in vitro.

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T lymphocytes play a central role in the regulation of airway inflammation in asthma, and T cell activation appears to be a characteristic feature of acute asthma. Follow-up data extending to 4 years indicate that the survival benefit persists in long-term therapy without cumulative toxic effects. Throughout the trialing of functions, involvement and feedback from patient care area managers and staff is crucial for successful automation.

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Fiber type is predominately fast compared to normal muscle as evidenced by contractile gene isoforms and decrease in oxidative metabolic gene transcription, despite a paradoxical increased transcription of slow fiber pathway genes. The status of each form, from when it is expected by the coordinating center to when it is accepted for statistical analysis, can be summarized by a single variable, maintained by the data manager.

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The SptAI and SbaI genes lie between an equivalent pair of bacteriophage P4-related open reading frames, one of which is a putative integrase gene, while the PvuII genes are adjacent to a mob operon and a XerCD recombination (cer) site. The congenitally helpless rat, selectively bred to model behavioral features of depression, has shown metabolic activity patterns in frontal and cingulate cortex similar to those detected in human imaging studies of depression and sadness. Histological modifications in carcinoma of the prostate during treatment with medroxyprogesterone acetate The present studies suggest that Asp104Lys mutant beta(1)-ARs triggers unconventional homologous internalization induced by G protein independent signals, where GRK2 and beta-arrestin1 play an important role for beta(1)-AR internalization. He received several awards but the most important was a Nobel Prize in Physiology or Medicine (1950).

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Component characteristics of thigh muscle volume in young and older healthy men. In vivo efficacy of antimicrobial-coated fabric from prosthetic heart valve sewing rings. Echocardiographic and clinicopathologic characterization of pericardial effusion in dogs: 107 cases (1985-2006). Inheritance patterns and gender of offspring were studied in relevant subsets of participants. The pharmaceutical industry urgently needs reliable pre-clinical models to evaluate the efficacy and safety of new chemical entities before they enter the clinical trials.

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Chromosome abnormalities in malignant melanoma: clinical significance of nonrandom chromosome abnormalities in 206 cases. Superoxide plays a crucial role in innate immunity to various pathogens.

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To investigate the potential role of protein-tyrosine phosphatases (PTPs) in regulated secretion, cellular PTP activity was measured in pancreatic beta cell lines after exposure to insulin secretagogues. In the present study, we tested the hypothesis that N-methyl-D-aspartate (NMDA) receptors on neurones of the caudal pontine reticular nucleus are involved in the mediation of fear-potentiated startle. Chronic radiation damage in the rat rectum: an analysis of the influences of fractionation, time and volume. Inertial load can affect the control of a dynamic system whenever parts of the system are accelerated or decelerated. The study was conducted for the 18-month period between 1 January 1999 and 30 June 2000.

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Since earlier studies have demonstrated the persistence of a stimulation effect after discontinuation of the stimulation train, we evaluated the clinical efficacy of VNS both in the programmed intermittent stimulation mode and magnet stimulation mode. Because noninvasive methods like ultrasound scanning or computed tomography cannot detect small-volume residual tumor, second-look laparotomy has been recommended for evaluation of treatment response in ovarian cancer. The plasmid pOV13 is a multicopy plasmid optimal in replication capacity (23kb). The polymerase chain reaction (PCR) amplification showed that several tested strains were negative for some primers.

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A third mutant, Undulated short tail, harbors a deletion of at least 48.3 kb, eliminating the Pax-1 locus as well as 38 kb of flanking sequences. To fully implement the concept of health promotion in Fiji, more attention needs to be given to the processes and structures that direct and support health promotion action. Accuracy and reproducibility of the IDS rapID STR system for species identification of streptococci.

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These findings show that the olfactory and visual representations of food, as well as the taste representation of food, in the primate orbitofrontal cortex are modulated by hunger. Neutral endopeptidase inhibition potentiates the effects of natriuretic peptides in renin transgenic rats. The optic neuritis often was bilateral and accompanied by papilledema.

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Mechanism of constitutive activation of FLT3 with internal tandem duplication in the juxtamembrane domain. Specimens were collected at surface level between November 2005 and May 2006.

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Electrostatic coupling between retinal isomerization and the ionization state of Glu-204: a general mechanism for proton release in bacteriorhodopsin. The effects of the convulsants L-allylglycine and bicuculline on the distribution of gamma-amino-butyric acid (GABA), glutamate and aspartate in rat brains were assessed immunocytochemically, using antisera raised against glutaraldehyde-protein conjugates of the respective amino acids. Quantitative analyses of transsynaptic granule cell death subsequent to the genetically determined degeneration of Purkinje cells in the cerebellum of pcd/pcd mutant mice show that granule neuron fallout follows a typical mathematical pattern of elemental decay. Our data indicate that SOX-13 represents a minor target of autoantibodies in patients with autoimmune diabetes.

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Comparison of three different methods for measuring classical pathway complement activity. A sperm midpiece defect in a Hereford bull with variable semen quality and freezability. The precise etiology of this serious complication remains unclear, but its occurrence argues against the application of intrapericardial defibrillator patches in this orientation. Unfortunately, high salt (hypertonicity) causes DNA damage and cell death.

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To define the relation between cigarette smoking and the risk of development of symptomatic adult onset coeliac disease. Drug overdose causes approximately 183,000 deaths worldwide annually and 50,000 deaths in Canada and the United States combined. Tyrosines 303/343/353 within the Sprouty-related domain of Spred2 are essential for its interaction with p85 and inhibitory effect on Ras/ERK activation. Thus, even though this was not a controlled study, our present results may be taken to indicate that long-term acyclovir or ganciclovir for all organ transplant recipients might be no longer totally justified.

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Half-Metallicity in One-Dimensional Metal Trihydride Molecular Nanowires. The tissue uptake of aminopropyron was almost constant at any temperature in the ileal non-everted sac experiments, while a decreased transfer of aminopropyron was observed with a decrease in temperature. Previous results had shown that the human leprosy bacilli possess a phenoloxidase, which, when compared with the enzyme from mammalian and plant sources, seemed unique in the range of substrates utilized and in the nature of the products formed.

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No hard data exist to indicate whether estrogen could be used as adjunct therapy for other depressive disorders during the menopausal transition or postmenopausal period, but newer findings suggest that estrogens may improve the effect of serotonin reuptake inhibitors. The results presented here show the prevalence and outcome of abdominal vascular injuries in a large collective within the TR DGU for the first time. Cows grazing the High nitrate pasture had significantly higher milk and plasma urea concentrations than cows grazing the Control pasture, while cows which were fed less concentrate had a notably higher plasma ammonia. Since January 1975, the start of the screening programme for breast cancer in the city of Nijmegen, The Netherlands, over 14 years have elapsed.

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