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Kenazol (Ketoconazole)
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Ketoconazole

Kenazol is the world’s first oral azole antifungal. First launched by Janssen Pharmaceutica (Belgium) in 1985, it transformed the treatment of oral and oesophageal candidiasis and some endemic mycoses such as coccidioidomycosis. This week, the FDA restricted its use to the occasional patient with endemic mycoses, as a last resort. The FDA cites “severe liver injuries and adrenal gland problems, and advising that it can lead to harmful drug interactions with other medications”, as the reason for it shift in position. Early after launch, Kenazol was extensively used for skin fungal infections, and was very effective for many and convenient. Unfortunately about 1 in 10,000-15,000 developed severe hepatic reactions, which were either fatal, or more recently required transplantation. Adrenal dysfunction is also a significant issue. Kenazol tablets are used throughout the world, as it is less expensive than other antifungals, but its use should be curtailed for all but the shortest courses. Fluconazole is a much safer alternative. Kenazol (Kenazol) shampoo carries no risk.

Other names for this medication:
Ketoconazole, Nizoral, Akorazol, Arcolan, Arcolane, Asquam, Biogel, Clarazole, Conazol, Daktagold, Daktarin, Dezor, Diazon, Dikoven, Eumicel, Extina, Funginoc, Fungoral, Ilgem, Kenazol, Kenazole, Ketazol, Ketokonazol, Ketolef, Ketovid, Ketozal, Liondox, Lizovag, Micoral, Micosin, Muzoral, Mycoderm, Noell, Orifungal, Oronazol, Panfungol, Perative, Phytoral, Pristinex, Tiniazol, Tinuvin, Xolegel, Yucomy, Zoloral,

Similar Products:
Clindacne, Azel, Neomox, Pantosec, Allopurinol, Gabiton, Omel, Epzicom, Solox, Viepax, Disulfiram, Ultop, Monast, Lopraxer, Spironolattone, Asquam, Harnalidge, Candazol, Abbotic, Lapikot, Ciprofloxacin, Stomex, Omestad, Klindan, Extina, Motivan, Cilamox, Asiviral, Criogel, Emeproton, Omezzol, Efexor, Tamsulosin, Cyclovir, Flavix, Clopes, Pradif, Duracan, Aspra, Vilitra, Ranclav, Sawacillin,

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An L-shaped incision combining an upper half mid-sternotomy and a left antero-lateral thoracotomy at the fourth intercostal space has been proposed by several authors for extensive aneurysms involving the aortic arch and the proximal thoracic descending aorta. We compared Hybrid Capture, a new technique for detection of human papillomaviruses (HPV), with a PCR assay based on L1 consensus primers. Coronary Artery Disease (CAD) remains the major cause of mortality and morbidity in the Western World. However, binding of only approximately 0.1 mol of ATP or ADP per mol of beta-subunit was detected using centrifuge columns. We performed linear regression analysis of joint angles at heel strike, midswing, and toe-off as a function of days into the study for each patient.

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Fruits underwent physiological disorders at 3 degrees C, evidenced by the appearance of surface injuries at the third day of storage, and, after moving the fruits to 20 degrees C, by increased respiratory activity and more intense ethylene production. A 71-year-old woman with hemodialysis underwent the edge to edge repair combined with ring-annuloplasty for mitral regurgitation caused by the anterior leaflet prolapse without any torn chordae. Chromaffin cell heterogeneity of process formation and neuropeptide content under control and nerve growth factor-altered conditions in cultures of chick embryonic adrenal gland.

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We also demonstrate that the widely used HEK293 cells have an unexpected relationship to neurons, a finding that may require reinterpretation of many previous studies in which it was assumed that HEK293 cells resembled more typical kidney epithelial cells. Cyclosporine-resistant allospecific cytotoxic cell precursors were demonstrated in human umbilical cord blood using a quantitative assay. Self-completion questionnaires were administered to 13- to 18-year-olds attending school in Zhejiang Province, eastern China.

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A sulfatide-reactive human monoclonal antibody obtained from a multiple sclerosis patient selectively binds to the surface of oligodendrocytes. Physical characteristics and radiological, mechanical and environmental performance were tested according to IEC-61526 Standard requirements. The authors believe that this report represents, to date, the most conclusive documentation of primary origin of a sarcoma in the seminal vesicle.

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In addition, the detection of parasite DNA by the polymerase chain reaction (PCR) was performed in all cases. These results suggest that women with epilepsy are not receiving adequate counseling and that care practices may not conform to those recommended. The Global Image Database (GID) is a web-based (http://www.gwer.ch/qv/gid/gid.ht m ) structured central repository for scientific annotated images.

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Functional analysis of the human cytochrome P4501A1 (CYP1A1) gene enhancer. Effects of St-587 and prazosin on water maze and passive avoidance performance of scopolamine-treated rats.

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In a 41-year-old hirsute woman, severe hypercalcemia led to the discovery of hyperparathyroidism related to the involvement (hyperplasia/or adenoma) of the 4 parathyroid glands. Here we present additional evidence in support of the hypothesis that the induction of Hsp27 and Hsp72 during acquired thermotolerance in Jurkat T-lymphocytes prevents apoptosis. Previous studies have established that aflatoxin production is induced by high levels of glucose (or other compatible carbohydrates). Cellular proteins were extracted and subjected to SDS-PAGE followed by Western blot detection and densitometric analysis.

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All statistical analyses demand uncertain inputs or assumptions. Using gel retardation and DNase I protection assays we identified maize proteins which bind to seven subterminal sites in both ends of Ac.

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The presence of the reflex was positively related to postoperative continence in patients older than 4 years but not in younger patients. In this study, plasma, urine, and blister fluid endothelin-1 concentrations were determined in burn patients and changes in vasoactive substances derived from endothelial cells secondary to burns were investigated. Steroid potentiation of beta-adrenergic-sensitive adenylate cyclase in rabbit ciliary processes. Comparative evaluation of a commercial enzyme immunoassay for the detection of human antibody to Rickettsia typhi.

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Although fluorescein angiography permits visualization of the retinal microcirculation in exquisite detail, visualization of the choroidal circulation is more limited. In the present study, experimental exposures to hyperbaric oxygen (HBO2) were performed (30-min exposure to 2.8 bar (280 kPa) pure oxygen).

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The aim of the present study was to evaluate the impact of canting correction in occlusal plane (OP) on the change of lip cant (LC) using three-dimensional (3D) photogrammetry in combination with cone-beam computed tomographic (CBCT) scans in class III asymmetric patients. To study the factors predictive for seizure control in non-ketotic hyperglycemic induced seizures (NKHS). Two of the 155 seropositive patients developed gastroduodenal malignancies. The most important interactions affecting carbamazepine pharmacokinetics are those resulting in induction or inhibition of its metabolism.

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Treatment of isolated pancreatic acini with high concentrations of cholecystokinin (CCK) is known to induce rapid changes in the cellular morphology. Rhythmical 7 Hz, 9 Hz electrical stimulation of the septum accelerated the conditioning.

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After extraction into ethyl acetate and separation by reversed-phase chromatography, EGCG, EGC, and EC were identified on the basis of their retention times and electrochemical characteristics. Moreover, the classification performances of neural and rule-based system are compared for each class of chromosome. Autocrine or paracrine stimulation of cell growth caused by the effect of PDGF on cells with induced receptors may be important in the formation of the proliferative lesions found in atherosclerosis and in certain forms of chronic inflammation. While awaiting rescue from a disabled submarine, survivors will likely endure an atmosphere of rising CO2 that will result in CO2 toxicity once the available emergency CO2 scrubbing materials are exhausted.

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Affective illness in children and adolescents: patterns of presentation in relation to pubertal maturation and family history. PMMA intraocular lenses with or without a heparin monolayer were exposed to Nd:YAG laser.

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Japanese Creutzfeldt-Jakob disease patients exhibiting high incidence of the E200K PRNP mutation and located in the basin of a river. Causes of sexual dysfunction: the role of anxiety and cognitive interference. A new nuclear gene for insect phylogenetics: dopa decarboxylase is informative of relationships within Heliothinae (Lepidoptera: Noctuidae). The study shows that relief of volume load on the left ventricle immediately leads to normalization of left ventricular function, especially if the myocardium was intact preoperatively. In part 2, involving 33 consecutive patients, CT was performed only when no solitary adenoma was identified with US or for road map information.

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The current treatment concept of ovarian cancer consists of radical surgery with subsequent chemotherapy. Single oral doses of desloratadine 5mg and fexofenadine 60mg taken without and with grapefruit juice (pretreatment with 240ml of double-strength juice three times daily for 2 days prior to administration of study drug, plus the same amount simultaneously with, and 2 hours after, the drug dose).

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Patients also showed less slowing of reaction time after error commission. Control of severe intra-abdominal hemorrhage with an infusible platelet-derived hemostatic agent in a nonhuman primate (rhesus macaque) model. What is the optimal surgical therapeutic target in functional ischemic mitral regurgitation: annulus, chord, ventricle, or papillary muscle? Numerous studies indicate that a wide variety of compounds, including the serotonin precursor, tryptophan, the serotonin receptor stimulant, fenfluramine, and the serotonin reuptake inhibitor, fluoxetine, are all capable of decreasing carbohydrate hunger, reducing consumption of carbohydrate-rich foods, and inhibiting weight gain in humans and animals. The role of physical assumptions in the microcrack representations and the different macroscopic internal variable representations of microcracks are discussed.

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While the mechanism that links the length of the leading Wnt system to that of the primordium remains unclear, we discuss how it might be determined by access to factors produced in the leading Wnt active zone that are required for collective migration of trailing cells. To highlight sociocultural factors reported to influence and strategies to promote breast and cervical cancer screening and early detection behaviors of racial and ethnic minority women. The pharmacokinetics (PK) of the photosensitizer tetra(m-hydroxyphenyl)chlorin (mTHPC) was measured by optical fiber-based light-induced fluorescence spectroscopy (LIFS) in the normal and tumoral cheek pouch mucosa of 29 Golden Syrian hamsters with chemically induced squamous cell carcinoma.

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For the follow-up period, however, there were no significant differences between these two groups. There continues to be debate about the actual definition of quality of life, and a concept that is difficult to define will naturally pose challenges to measurement.

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The use TNF-alpha as immunomodulator made it possible to decrease the dose of the preparation of F.tularensis OM introduced as immunogenic agent without essential changes in the number of splenic APC and in the level of tularemia antibodies. Neuroleptic drugs in the treatment of acute psychosis: how much do we really know?

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This difference was due to a subgroup of 4 children in the dyslexia group who had particular difficulty with the ART. The biology of hydatid disease, including the complex interaction between primary and secondary hosts, is reviewed. In order to evaluate the relevance of in vitro methods for immunotoxicity assessment, the effects of pharmaceutical drugs on lymphoproliferative and cytotoxic functions of mouse splenocytes and human peripheral blood mononuclear cells (hPBMC) were studied.

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Arbuscular mycorrhizal fungi (AMF) are members of the phylum Glomeromycota, an early divergent fungal lineage that forms symbiotic associations with the large majority of land plants. Furthermore, they participate in a variety of other (patho)biological processes such as embryonic development, reproduction, wound healing, cancer and brain function. The data are available for archiving, distributing and for post-acquisition manipulations. Cartilage degeneration was induced in the hind knees of guinea-pigs by surgery.

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In-vivo studies with the opioid antagonist, 16-methylcyprenorphine. This paper describes with two patients with pulmonary disease due to Mycobacterium szulgai. This study utilized two age groups of mice, the younger mice at 1-2.5 months of age, and the older mice at 11-12 months of age. The treating physician should realize that victims of abuse, after the passage of time, will eventually fall sick and consult a doctor for physical or/and psychological symptoms which are the result of the past abuse. Hepatic extraction of amino acids, galactose, and ammonia in cirrhosis.

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European courses of neurosurgery and other training and postgraduate education activities of the European Association of Neurosurgical Societies. Reproductive and sexual physiology, changes in body composition and mental performance in the aging male cannot simply be reduced to presumptive hypogonadism defined by low androgen serum levels or by decreasing levels of growth hormone (GH) and melatonin. This procedure incorporates correction of chordee, mobilization of the urethrocutaneous flap, and advancement of the flap through a tunnel until it reaches the tip of the glans.

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We have examined the opposing influences of the protein-protein (PP) energy, which favors the native state, and the protein-solvent (PS) energy, which favors unfolding, in the formation of the beta-hairpin structure. Palladium-catalyzed alpha-arylation of esters and protected amino acids. Depending on the primary site of injury the fibrosis may be present in the hepatic parenchyma as seen in chronic hepatitis or may be restricted to the portal areas as in most biliary diseases.

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In all cases the endoscopic fenestration was the unique treatment and allowed to avoid the definitive ventriculoperitoneal shunt. Finally, the post-synaptic consequences of prolonged and supranormal dopaminergic activation need to be investigated in order to understand what persistent neuroadaptations result from chronic activation of this neuromodulatory system (e.g.

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This article presents Bullard laryngoscopy and submandibular intubation techniques as innovative alternative methods of airway management during surgery. This article reviews available rodent models to study obesity and attempts to highlight the greatest utility for each model.

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During the second evaluation the female subjects had significantly higher metabolism only in the cerebellum. We questioned whether the AA-genotype interferes with weight stabilization after weight loss. Additionally, in mouse macrophages, LPS increased the mRNA for smTLR4.

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The possible mechanisms that may impair growth in the different forms of anemias are addressed with special attention to their effect on the growth hormone (GH) - insulin like growth factor -I (IGF-I). Biophysical studies demonstrated a complex behavior in terms of membrane perturbation, which can range from pore formation to micellization (carpet model). Several clinical study groups in the world have studied prognostic factors and it has been shown that the chromosomal abnormality of AML cells is closely related to the response to the chemotherapy. Single-chain antibody-mediated gene delivery into ErbB2-positive human breast cancer cells. In this study, we compared the 1975 Japanese diet, which has been found to have high health benefits, with the 2010 Italian diet, which contributes to the longest life expectancy in Mediterranean countries.

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Axon outgrowth, synapse formation, and synapse function, among other physiological processes, require active transport of these cargos between the neuronal soma and axon terminals. Urinary chorionic gonadotropin excretion in the monkey (Macaca mulatta)--early phase. Because the displaced strand is cleaved when GGH is placed on either PNA strand, the D-loop must be close to the backbone of the bis-PNA-DNA triplex. This methodology was successfully applied to the synthesis of the racemic form of the marketed antidepressant sertraline. At 37 degrees C, p-nitrophenol glucuronidation was equivalent in catfish and rat microsomes.

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Self-medication for malaria is widely practised around the world, and although many home treatment episodes are successful, the risk of under or over-dosing is always present. The peripheral muscles, one long and one short, lie on each border of the foot and reach the proximal phalanges of the digits only.

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vaccination with PspA and IL-12 provided increased protection against nasopharyngeal carriage. The 140-kDa RR1 protein from both herpes simplex virus type 1 and type 2 (HSV-1 and HSV-2) functions as the large subunit of viral ribonucleotide reductase (RR) and contains an intrinsic serine/threonine protein kinase (PK) activity at the unique NH2-terminal domain.

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A novel, double mutation in DNA gyrase A of Escherichia coli conferring resistance to quinolone antibiotics. CD4 positive Leu-8 negative helper-inducer T cells predominate in the human intestinal lamina propria. Prospective evaluation of pain, swelling, and disability from copperhead envenomation. Physical exercise can counteract this tendency by influencing such factors.

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MRI revealed an acute infarction in the left lateral pons of anterior inferior cerebellar artery (AICA) territory. The ability of DA to act at the pituitary and thereby inhibit the secretion of these three hormones suggests that other regulatory factors must provide the specificity needed for the differential secretion of the individual hormones during varying physiological states.

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EPR and electron microscopy experiments show that the aggregates spontaneously formed by these surfactants are a mixture of multilamellar vescicles. hu-PBL-SCID mice immunized with CVP-pulsed autologous dendritic cells were able to mount a specific human primary antibody response against the gp41-derived epitope. The realistic model has provided an additional condition for the application of this method to invert nerve fiber recruitment, i.e., real or virtual anodes should be close to the cathode.

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Basic Training Program in Medical Pedagogy: a 1-year program for medical faculty. Owing to the increasing numbers of patients with end-stage congestive heart failure awaiting heart transplant and the limited number of suitable donor organs, a decrease in stringency of donor criteria has become widely accepted over the last decade. We investigated the effect of plant lectins, carbohydrates and inhibitors of the cytoskeleton on proMMP-2 activation in normal (HLF1) and malignant fibroblast (HT1080) cells.

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Dispersed cultures of DRG collected from rat fetuses at gestational day 15 also contained epitopes for VDR and calbindin-D(28k) in neurons, but not in glial cells. In vitro efficacy of several antimicrobial combinations against Brucella canis and Brucella melitensis strains isolated from dogs. Endometriosis predominantly affects the pelvic reproductive organs but can also affect the urinary tract.

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Invertebrate smooth muscle differs from that of vertebrates principally in the higher proportion and larger diameter of thick myofilaments. Hyperleukocytosis: pseudohyperkalaemia and other biochemical abnormalities in hyperleukocytosis. Algae as nutritional and functional food sources: revisiting our understanding. The clinical and radiological evolution was satisfactory, without postoperative complications and the most important, avoided an amputation with a better quality of life. Vitreous levels of VEGF are significantly elevated in eyes with non-age-related subretinal neovascularisation compared with eyes with FTMH but not as elevated as in PDR.

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Confocal immunofluorescence revealed EBP50 was concentrated at the apical domain of both cell types. Normal myocardial function in severe right ventricular volume overload hypertrophy. The putative dalsan 20 mg adderall catalytic domain of MAPKKK5 shows significant sequence homology to the kinase domains of the MAPKKK/MEKK level protein kinases from mouse MEKK2 and -3, Drosophila melanogaster PK92B, Saccharomyces cerevisiae STE11, and Schizosaccharomyces pombe BYR2.

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The MAP kinase pathway is required chemical pleurodesis with tetracycline uses for RNT-1 stabilization, and RNT-1 was phosphorylated by SEK-1/PMK-1 in vitro. Polymorphism and peculiar clinical manifestations in blind-and-deaf children with oligophrenia were demonstrated.

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Nigeria has a high population density but a weak health-care system. In Spain there are experiences since 1995 and an important development and this paper is to investigate the actions pantoprazole magnesium nursing implications for albuterol required for a more widespread use in trials. Internalization of 125I-GRP, assessed using an acid wash, was maximal after 10-20 min, and was clathrin-mediated since it was inhibited by hyperosmolar sucrose and phenylarsine oxide. Assessment of laminin-mediated glioma invasion in vitro and by glioma tumors engrafted within rat spinal cord.

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Effect of changes in scrotal temperature on food intake in pigs. The purpose of this study was to test a model of adult drinking that incorporated the potentially important risk factor of partner drinking and in which proximal risk factors (peer drinking, alcohol expectancies) were hypothesized to be strongly associated with adult alcohol use and to mediate relationships between more tamsulosin hcl 0.4mg cap natural substitute distal risk factors and drinking.

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Several important signal transduction pathways have been implicated in the regulation of the physiological processes of CR leading to increased lifespan. Community care workers were more satisfied with various facets of job satisfaction including work on their present job, supervision, people in their present job and the job in general. Both norepinephrine release and upregulation of cardiac losita bhattacharya australia beta-adrenoceptors lead to an adrenergic overstimulation of ischemic myocardium. Using a retrospective chart audit of a 237-bed acute care hospital, the author examined 150 diagnostic statements written by registered nurses.

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Changes in relationship satisfaction across the transition to parenthood: a meta-analysis. In the treatment of endometrial cancer, surgical treatment, radiotherapy, chemotherapy, and hormonal therapy are available. The attentrol vs adderall medication possibility of congener production in blood during storage was studied. The porphyrias are a group of disorders caused by deficiencies in the activities of the enzymes of the heme biosynthetic pathway. In vivo RAGE expression was examined in models of hepatic fibrosis induced by bile duct ligation or thioacetamide.

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In the first experiment, the degraded images were perceptually combined by being separately presented to each eye in a dichoptic viewing situation. Because ROIs, through activation of NF kappa B, can also induce expression of cellular genes involved in immune and inflammatory responses, the ROI response to CMV infection may also represent a parallel survival mechanism that has evolved in the host cell to protect against viral infection. Several studies have demonstrated that non-selective opioid receptor antagonists effectively reduce alcohol consumption in both animal models and at the clinical level. group manager vs pexeva Gender schema and gender role discrepancy as correlates of body image.

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