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In this study, we investigated to see whether intrathecal gabapentin produces antihyperalgesic effects on thermal and mechanical hyperalgesia in neuropathic rats and whether its effects are associated with motor impairment. All the significant changes were small and the potential of the investigated blood components as diagnostic markers is therefore minimal. KEGG is an integrated database resource for linking sequences to biological functions from molecular to higher levels.

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Forty-one men and three women infected with HIV and treated with HAART, and 15 healthy hospital staff members were immunized with trivalent influenza subunit vaccine. Numerous types of food products have been implicated in listeriosis infections, but of particular concern are ready to eat products such as lunchmeats, hotdogs, ham/chicken salad, sausages, and roast beef. We investigated these two hypotheses in a chorusing anuran, the hylid Hyla arborea, through a series of phonotaxis experiments conducted within a six-speaker arena in a high background noise situation, by presenting females with male calls containing either single or multiple attractive call components, and by modifying distances between speakers. To prevent further stent migration it is necessary to remove the stent via a guidewire.

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An original experience for the medical faculty in Geneva: the community health certificate The FISH assay detecting EBV copies in unfractionated whole blood is preferable and superior to plasma real-time PCR in its reflection of the absolute viral burden circulating in the patients. Successful LUTS management results in FSD improvement, but the mechanisms are ill understood.

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Volumetric determination of fats in margarine using the indirect complexometry with Mg(II) Montelukast patients had better adherence to their treatment regimen and required fewer beta-agonist prescriptions, which is an indicator of asthma control and possibly therapeutic effectiveness. The aim of this study was to assess the efficacy of double-dose (0.2 mmol/kg cumulative dose) gadopentetate dimeglumine (Gd-DTPA) in patients with intraparenchymal brain metastasis. Presumably, this imbalance between excitatory and inhibitory input into muscles leads to convulsions.

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Their toxicological properties lead among others to disturbances of the central nervous system. Bronchoalveolar lavage was performed in 128 pigs from five fattening units showing acute pneumonia (48 animals), subclinical purulent pneumonia (17 animals), and chronic purulent pneumonia (63 animals). In this study, the preventive effects of these agents were examined on late-phase injury mediated by infiltrating neutrophils, a more severe condition than the initial one.

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Upregulation of CD80 on the leukaemic cells was mandatory for the induction of such a specific T-cell response. Fifty-seven black and 207 white patients completed measures of anxiety, depression, disability, pain, and physical symptoms during their initial visit to a university pain clinic. A low cost thermistor temperature alarm is described which indicates by means of different coloured lights if the temperature falls below 30 degrees C, lies between 30 and 37 degrees C, or if the temperature exceeds 37 degrees C.

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Thus, it can be hypothesized that continued exposure to environmental carcinogens (ie, longstanding history of smoking and drinking), loss of proper cell cycle control (eg, inactivation of p53 or p16 tumor suppressor genes or amplification of the proto-oncongene cyclin D1), and impaired DNA repair capacity (both inherited and acquired) are prerequisites in head and neck carcinogenesis. Germ line mutations have not to be inherited, they can result from a spontaneous mutation occurring during gametogenesis in one patient. Further studies are necessary to better define the pathogenicity and natural history of this distinct new virus, HIV-2/HTLV-4. We firstly identified RCC1 gene hypermethylation in gastric tumor tissues using the differential methylation hybridization (DMH) microarray, but the role of RCC1 in the pathogenesis of gastric carcinoma is largely unknown.

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Patient notes of 39 of these were available for examination for evidence of the day 1 culture report, the accuracy of that report and evidence of clinical interpretation. In the nervous system, extracellular matrix components are believed to influence cell shape, proliferation and migration during development and following injury. Genotyping and association analysis were performed at Cedars-Sinai Medical Center. Enzymatic activity and its interrelationship with sulfhydryl groups in diabetes mellitus Frequency of pulmonary embolism in patients who have iliofemoral deep vein thrombosis and are treated with once- or twice-daily low-molecular-weight heparin.

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Stillbirth, neonatal death and sudden infant death (SIDS): parental reactions. Only a longitudinal study of the physiological situation appears to allow the necessary conditions for detecting overtraining in the early stages of its process for each subject. Hepatitis C virus (HCV) is the major cause of transfusion-acquired non-A, non-B hepatitis. Isolated working guinea pig hearts, perfused with glucose fortified Krebs-Henseleit, were subjected to 60 min global low flow ischaemia followed by 30 min reperfusion.

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The liver biopsies of two normal individuals were also studied in the same conditions. Additionally, epidermal growth factor-stimulated migration of CaCO-2 cells was abolished by DPI and Nox1 siRNAs, indicating the requirement of Nox1 activity for the motogenic effect of epidermal growth factor. Association between global DNA hypomethylation in leukocytes and risk of breast cancer. Sera from patients undergoing chronic intermittent hemodialysis were assayed before and after one hemodialysis session.

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Severe community-acquired pneumonia: current outcomes, epidemiology, etiology, and therapy. The heart specimens were processed for histological examination. Fluorescent acid-fast microscopy for measuring phagocytosis of Mycobacterium avium, Mycobacterium intracellulare, and Mycobacterium scrofulaceum by Tetrahymena pyriformis and their intracellular growth.

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The operating room theatre: programme for today, design for 2001. Long-term effect of epalrestat, an aldose reductase inhibitor, on the development of incipient diabetic nephropathy in Type 2 diabetic patients. Plots of adsorption against the inverse of the area per cholesterol molecule revealed two linear revealed two linear regions, corresponding to penetration at high and low monolayer areas.

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The incidence of cancer in contralateral reduction mammaplasty after mastectomy and reconstruction of the removed breast. A new approach to the determination of human breath acetone with particle-packed sample preparation needle was developed. Higher mobility of labeled tribenuron-methyl in plants with multiple resistance was, however, similar to plants with only 2,4-D resistance, indicating the presence of non-target-site resistance mechanisms (NTSR).

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There was a typical patternless growth of short fascicles and a short storiform arrangement of cells in the stroma with varying degrees of collagenization. A 31-year-old had a five-year history of painless progressive swelling of her right upper eyelid. Investigation of the mechanisms of guided cell migration can contribute to our understanding of many crucial biological processes, such as development and regeneration. The anaerobic decomposition of benzoic acid during methane fermentation.

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Effect of a novel immunosuppressant, FTY720, on allograft survival after renal transplant in rats. Breast cancer patients with type-2 diabetes mellitus were at risk of a poor prognosis. We report a case with a chronologic association between ovarian endometriosis showing foci of atypia and a subsequent large clear-cell carcinoma arising in the same ovary 3 years later. Whereas the plasma and LDL antioxidant status do not appear to be affected by fish oil supplementation, an increased susceptibility of LDL to oxidation was observed in these healthy volunteers. The free sterol mixture of the sponge Psammaplysilla purpurea was shown to contain aplysterol as the major constituent.

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ADP-ribosylated actin had no effect on the rate of polymerization of gelsolin-capped actin filaments which polymerize at the pointed ends. Effects of 5-HT4 receptor antagonists on rat behaviour in the elevated plus-maze test. truncatula transporters in several databases, until now there has been no available systematic database that includes all transporters in M. Using the London Metropolitan Police as a case study, the paper suggests that working conditions in the Victorian and Edwardian police had detrimental effects on the health of officers. Prolonged ambulatory pH monitoring in patients with persistent gastroesophageal reflux disease symptoms: testing while on therapy identifies the need for more aggressive anti-reflux therapy.

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Geometric isomers of a photoactivable general anesthetic delineate a binding site on adenylate kinase. Thirty-one first-episode psychotic patients were assessed via a semistructured interview to determine the presence or absence of the 8 DSM-III prodromal symptoms. Fatty acid content of plasma lipids and erythrocyte phospholipids are altered following burn injury. Awaiting these, the beneficial effect of multidisciplinary care of ALS patients on survival and quality of life has become clear.

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A founder mutation of the BRCA1 gene in Western Sweden associated with a high incidence of breast and ovarian cancer. For the canine and M2(2), upper and lower homologues appear to begin development at different times, but there is no apparent difference in onset times between other upper and lower homologues. This procedure involves enclosing the prosthesis and the vessel while keeping the vascular axis straight without any kinking. Enzymatic preparation of heparin oligosaccharides containing antithrombin III binding sites.

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During the experiment different cardiovascular, fluid-electrolyte and biochemical parameters were recorded. The combination of docetaxel, gemcitabine, and thalidomide might be an active regimen for platinum-resistant ovarian nondysgerminomas and further investigation of this combination is warranted. Knowledge regarding functional ligand-receptor interactions as presented in this study will be important for the design and interpretation of in vivo experiments, e.g., loss-of-function studies in transgenic mice. Screening has the potential to cause harm, and there is an ethical imperative to seek out strategies that provide balanced information on cancer screening.

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Sequence analysis and expression data confirmed the relevance of the RTP801 target gene in rabbits and the utility of this species as a relevant animal model. SUPPORT Tools for evidence-informed health Policymaking (STP) 1: What is evidence-informed policymaking?

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In soybean cells, sustained accumulation of H2O2 from an oxidative burst cues localized host cell death. To construct the eukaryotic expression vector hypoxia-inducible factor 1alpha-pcDNA(3.1) and to investigate its transfective efficiency into mesenchymal stem cells (MSCs) in vitro and the expression of HIF-1alpha gene in MSCs.

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Five human studies reported no significant difference in CBL around implants placed at the test and control sites. This phenomenon is known as the gut origin of sepsis hypothesis. Thymectomy of 3-day-old mice induces organ-specific autoimmune disease, which is characterized by the presence of autoantibodies and T-cell infiltrates in the affected organs. Each subject was symptomatic, and nine also complained of bleeding.

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Effectiveness of limited cone-beam computed tomography in the detection of horizontal root fracture. The standard tangential fields do not entirely include Levels I and II axillary nodes. Six patients developed colonic pseudoobstruction after the use of morphine sulfate administered via a PCA infuser. Heterophyid parasites of man from Idku, Maryut and Manzala lakes areas in Egypt.

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The intravenous administration of the cyclooxigenase blocking indomethacin results in a very rapid and sharp decrease of renal blood flow (RBF) and in a decrease of water and sodium excretion in anesthetized dogs. An aneuploid tumour was defined as one that displayed an additional distinct peak. Overall, men reported significantly higher levels of work-to-family and strain-based, family-to-work conflict. The chymosin-sensitive sequence of bovine k-casein A (kappa-CN A) was investigated as a cleavable linker site between the two domains of a streptavidin-chloramphenicol acetyltransferase fusion protein. The usual course of the lateral femoral cutaneous nerve is deep to the lateral end of the inguinal ligament but superficial to the sartorius muscle.

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This review provides a general understanding of vaginal drug delivery, its challenges, and nanoparticulate delivery systems. Pravastatin reduces steroid-induced osteonecrosis of the femoral head in SHRSP rats.

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Logarithmic transformations of the standardised rates for mortality due to ischaemic heart diseases for both sexes were performed and the regression lines were adjusted. Gallbladder carcinoma (GBCA) is the most common malignancy of the biliary tract and is often found seredipitiously after cholecystectomy. The heart rate, respiratory rate and degree of sedation were recorded before and 30 minutes after administration of the drugs. Successful living placement for adults with disabilities: considerations for social work practice.

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The nonproductive decomposition of both Mn(III) and peroxide is an important finding with implications for proposed in vitro uses of the enzyme and for its role in lignin degradation. The clinical presentation of dogs with amegakaryocytic thrombocytopenia and primary peripheral immune-mediated thrombocytopenia is similar, but dogs with amegakaryocytic thrombocytopenia had a more severe clinical course compared to primary peripheral immune-mediated thrombocytopenia dogs. Genetically engineered livestock for agriculture: a generation after the first transgenic animal research conference. The present method can be used to accommodate larger DNAs in the B.

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Accordingly, the time courses of functional recovery in hibernating and stunned myocardium were compared. Release of macrophage migration inhibitory factor by virus-infected spleen cells. Studies on the metabolism of acetate-1-C in tissues of tumor-bearing rats. The use of lasers in dentistry remains controversial, in spite of their increasing application in medical practice.

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Women were interviewed to elicit sociodemographic characteristics, out-of-pocket expenditures, and CY program details. While the data are too preliminary to elucide the mechanisms for the raised Sm-C, the concurrent increase in Sm-C and human placental lactogen (hPL) raises the possibility that hPL may mediate the increment in Sm-C. The results show that NDST1 and NDST2 are dispensable for mesodermal differentiation into osteoblasts but necessary for induction of adipocytes and neural cells.

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Summary of the results of substantial studies published on this topic. To determine whether ANF is relevant in the regulation of ACTH secretion in the ovine foetus, the present study examines the effect of ANF on CRH-stimulated ACTH release in the mature ovine foetus. Immunological reactivity and passive protective activity of monoclonal antibodies against protective antigen (PAg) of Leptospira interrogans serovar lai.

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The widespread use of DDAVP has been the primary addition to treatment strategies over the past decade. Microleakage in endodontically treated teeth: influence of calcium hydroxide dressing following bleaching. Molecular pathophysiology of psoriasis and molecular targets of antipsoriatic therapy. The juxtamembrane lysine and arginine residues of surfactant protein C precursor influence palmitoylation via effects on trafficking. The peak absorbance and emission of methylene blue as a near-infrared fluorophore occur at 667 nm and 686 nm, respectively.

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Cognitive mechanisms which might account for the observed pattern of lateralisation are discussed. In human macrophage-like U937 cells, carvacrol suppressed lipopolysaccharide-induced COX-2 mRNA and protein expression, suggesting that carvacrol regulates COX-2 expression through its agonistic effect on PPARgamma. Radioactive assay of aryl hydrocarbon monooxygenase and epoxide hydrase. An extensor pollicis longus tendon, ruptured after treatment of a giant cell tumor of the distal radius by packing the cavity with polymethylmethacrylate cement. In the rat sciatic nerve crush injury model, we found that collagen-binding NGF could be retained and concentrated at the nerve injured site to promote nerve repair and enhance function recovery following nerve damage.

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Cells arrested in G1 by the v-Abl tyrosine kinase do not express cyclin A despite the hyperphosphorylation of RB. This paper reports the findings of an interview survey of all 57 health visitors working in Clydebank and the north-west area of Glasgow, concerning their role in child home accident prevention. Our results indicate that EGFR-PLCgamma1 signaling mediates HG-induced PKCbeta1-Akt activation and subsequent collagen I upregulation in MC. Owing to the existing controversy about the role of life-style in the pathogenesis of BPH, the possible associations of LUTS and prostate enlargement with alcohol intake, coffee consumption, smoking, physical activity, body mass index (BMI) and concomitant diseases were studied in the large series of patients of the QUIBUS study. To assess whether recent epidemiologic evidence supports an association between use of estrogen replacement therapy or hormone replacement therapy and risk of breast cancer.

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Although delivery of bleomycin to induce acute lung injury is the most well-studied animal model of pulmonary fibrosis, there is considerable interest to pursue other models to understand the common and/or specific pathological mechanisms. Testicular-associated immune deviation (TAID) has thus far been induced and studied only in the rat and the present study was planned to study if TAID could be induced in mice as well. There was no significant difference between autograft and deep-freeze stored allograft 24 weeks after operation, but there was a significant difference in the fresh allograft 3 weeks after grafting. Multiscale modeling and integration of physiological models carry challenges due to the complex nature of physiological processes. To maximise the FC removal efficiency the polishing pond was constructed with the objective of approaching a plug flow regime.

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Disruption of the permeability of blood-tissue barriers in mechanisms of primary reaction to irradiation A bipolar recording electrode made of stainless steel wire was attached to its wall.(ABSTRACT TRUNCATED AT 250 WORDS) Myocardial stunning, known as stress cardiomyopathy, broken-heart syndrome, transient left ventricular apical ballooning, and Takotsubo cardiomyopathy, has been reported after many extracardiac stressors, but not following chemotherapy. However, small intestinal metastasis from renal cell carcinoma is rare. Basement membrane structure in situ: evidence for lateral associations in the type IV collagen network.

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Relationships between in vivo and in vitro pH and bacterial attachment. One patient was operated on with this technique grafting the left anterior descending artery with the left internal mammary artery and grafting sequentially the first diagonal branch and the first marginal branch with a T-graft of radial artery. However, the cardiorespiratory responses to NTS stimulation have no substantial role in altering ICSS, because vagotomy abolished the heart rate effects of NTS stimulation but caused no change in its reducing effect on ICSS. It is concluded that clonidine produces its hypotensive response by acting on alpha-adrenergic receptors of bulbar CVN.